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Free vibration and transient response of double curved beams connected by intermediate straight beams

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 37-62页

作者： R.A.JAFARI-TALOOKOLAEI h.GhANDVAR E.JUMAEV s.KhATIR T.CUONG-LE school of Mechanical Engineering Babol Noshirvani University of Technology Department of Mechanical Engineering Faculty of Engineering New Uzbekistan University University of Business and science Center for Engineering Application and Technology solutions Ho Chi Minh City Open University

This paper investigates the free vibration and transient response of interconnected structures including double curved beams and intermediate straight beams,which are all constructed from functionally graded porous(FGP) materials. The strain potential and kinetic energies of each beam along with the work done by the external force are calculated. Additionally, a higher-order beam element is introduced to derive stiffness and mass matrices, along with the force vector. The curved and straight beams are discretized, and their assembled stiffness, mass matrices, and force vectors, are *** conditions at the joints are used to derive the total matrices of the entire structure. subsequently, the natural frequencies and transient response of the system are determined. The accuracy of the mathematical model and the self-developed computer program is validated through the comparison of the obtained results with those of the existing literature and commercial software ANsYs, demonstrating excellent ***, a comprehensive study is conducted to investigate the effects of various parameters on the free vibration and transient response of the considered structure.

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Neuroinflammation as a therapeutic target in huntington's disease

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Neural Regeneration Research 2025年第3期20卷 817-818页

作者： Andrea Kwakowsky Thulani h.Palpagama Center for Brain Research and Department of Anatomy and Medical Imaging Faculty of Medical and Health SciencesUniversity of AucklandAucklandNew Zealand Pharmacology and Therapeutics School of MedicineGalway Neuroscience CentreUniversity of GalwayGalwayIreland

In 1872, George huntington presented his essay “On Chorea” to the Meigs and Mason Academy of Medicine and, in doing so, detailed a disease that would later bear his name. huntington's disease(hD) is a genetic, neurodegenerative disease that manifests as the loss of motor control,cognitive impairment,and mood and psychiatric changes in paents.

关键词： huntington inflammation Medicine

Glial response in the midcingulate cortex in huntington’s disease

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Neural Regeneration Research 2025年第1期20卷 207-208页

作者： Thulani h.Palpagama Andrea Kwakowsky Center for Brain Research and Department of Anatomy and Medical Imaging Faculty of Medical and Health SciencesUniversity of AucklandAucklandNew Zealand Pharmacology and Therapeutics School of MedicineGalway Neuroscience CenterUniversity of GalwayGalwayIreland

huntington’s disease(hD)is a genetic disease characterized by the progressive degeneration of the striatum and *** can present with a variety of symptoms that can broadly be classified into motor symptoms,inclusive of choreatic movements and rigidity,mood and psychiatric symptoms,such as depression and apathy,and cognitive symptoms,such as cognitive *** causal mutation underlying hD results from an expansion of a CAG repeat sequence on the IT15 gene,resulting in the formation and accumulation of a mutant huntingtin protein.

关键词： huntington degeneration cortex

Comparative chemical sensor for detection of chromium(Ⅵ) in aqueous solution

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Optoelectronics Letters 2025年第1期21卷 21-27页

作者： sura h.AL-REKABI A.A.ALWAhIB Electrical Technique Department Al Suwayrah Technical Institute Middle Technical University Laser and Optoelectronics Department University of Technology-Iraq

A process for purifying aqueous solutions containing heavy and toxic metals such as chromium（Cr） has been investigated. One of the extremely harmful pollutants in rivers and seawater is the heavy metal ions due to their direct impacts on human, animals and plants are hexavalent Cr（Ⅵ）. Consequently, highly sensitive sensor to detect Cr is essential. surface plasmon resonance（sPR） technique has attracted huge research interest in detecting heavy metals specifically. In this study, three types of prism-based sPR sensor, gold（Au）/silver（Ag）, Au/polyaniline（PANI） and Au/titanium dioxide（TiO2） nanostructured films, are investigated as potential sensing material to detect the presence of Cr（Ⅵ） ions in water. The base Au layer with thickness of 48.3 nm is deposited on a glass slide for all sensors. For Au/Ag, Au/PANI nanofibers and Au/TiO2sensor films, the Cr（Ⅵ） concentration is varied from 1 ppm to 15 ppm with sensitivity of 0.270 °ppm-1, 0.082 °ppm-1and 0.039 °ppm-1, respectively. Based on these results, the Au/PANI nanofibers are the most sensitive to Cr（Ⅵ） among the tested sensing materials.

关键词： Titanium dioxide

Does mesenchymal stem cell’s secretome affect spinal sensory circuits?Implication for pain therapies

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Neural Regeneration Research 2025年第1期20卷 181-183页

作者： Francesco Ferrini Esri h.Juárez Adalberto Merighi Department of Veterinary sciences University of TurinGrugliascoTOItaly Department of Psychiatry and Neuroscience UniversitéLavalQuébec CityQCCanada

Mesenchymal stem cells(MsCs)are multipotent adult stem cells of mesodermal origin that can be isolated from various tissues,including bone marrow,tooth pulp,adipose tissue,and umbilical *** have gained significant attention in regenerative medicine due to their ability to modulate the immune system and favor tissue *** enrich the medium in which they are cultivated with a broad range of bioactive molecules,including growth factors,cytokines,chemokines,enzymes,nucleic acids,and extracellular vesicles that collectively compose the MsC *** increasing number of pre-clinical studies suggest that delivering in vivo an MsC-conditioned medium(i.e.,the medium collected from MsC cultures after at least 3 days of exposure)exerts neuroprotective and anti-inflammatory effects in a variety of neurological conditions.

关键词： protective clinical collective

Dynamic stress concentration in an infinitely long cylindrical cavity due to a point spherical source embedded within a fluid-saturated poroelastic formation of infinite extent

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 139-156页

作者： h.hOssEINI O.BALILAshAKI Department of Mechanical Engineering Faculty of EngineeringGolestan University

The effects of a harmonically exciting monopole source on an infinitely long cylindrical cavity embedded entirely within a fluid-saturated poroelastic formation of infinite extent are examined theoretically. It is assumed that the source is located outside the cavity at a specified distance from the borehole axis. The magnitudes of the hoop and radial stresses beside the pore pressures exerted on the interface and inside the porous medium surrounding the borehole are calculated and discussed. Biot's poroelastic modeling along with three types of boundary conditions for the cylindrical interface including the ideal fluid, empty borehole, and rigid inclusion with a hard boundary is employed for the analysis. Utilizing a proper translational addition theorem for expressing the incident spherical wave in terms of cylindrical wave expansions, the proposed boundary conditions at the interface are satisfied. stresses are formulated by means of wave potential functions in a three-dimensional(3D) manner. The effects of the frequency and the radial distance between the source and borehole on the induced stresses are examined for the first cylindrical modes over frequency spectra. Two permeability conditions for the interface and three types of soils for the porous formation are considered throughout the analysis. To give an overall outline of the study, a numerical example is presented. The results clearly indicate that the distance is a key parameter and has considerable effects on the induced stress values. In addition, the interface permeability condition and soil characteristics play an important role in determining the dynamic response of the borehole. Finally,the obtained results are compared with the relevant analyses existing in the literature for some limit cases, and good agreement is achieved.

关键词： point source cylindrical cavity porous medium wave-field transformation stress concentration O353.4

shrinkage of magnetosphere observed by TC-1 satellite during the high-speed solar wind stream

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science China(Technological sciences) 2008年第10期51卷 1695-1703页

作者： h. RME I. DANDOURAs C. M. carr Centre d'Etude spatiale des Rayonnements BP 4346 31028 Toulouse cedex 4 France The Blackett Laboratory Imperial College London SW7 2BZ UK

During the interval 06:14―07:30 UT on August 24, 2005, since the Earth’s magneto- pause was suddenly compressed by the persistent high-speed solar wind stream with the southward component of the interplanetary magnetic field (IMF), the magnetopause moved inward for about 3.1 RE. Meanwhile, TC-1 satellite shifted from northern plasma sheet to the northern lobe/mantle region, although it kept inward flying during the interval 06:00―07:30UT. The shift of TC-1 from the plasma sheet to the lobe/mantle is caused by the simultaneous inward displacements of the plasma sheet and near-Earth lobe/mantle region, and their inward movement velocity is larger than the inward motion velocity of TC-1. The joint inward dis-placements of the magnetopause, the lobe/mantle region and the plasma sheet indicate that the whole magnetosphere shrinks inward due to the magnetospheric compression by the high-speed solar wind stream, and the magnetospheric ions are attached to the magnetic field lines (i.e. ‘frozen’ in magnetic field) and move inward in the shrinking process of magnetosphere. The large shrinkage of magne-tosphere indicates that the near-Earth magnetotail compression caused by the strong solar wind dynamic pressure is much larger than its thickening caused by the southward component of the IMF, and the locations of magnetospheric regions with different plasmas vary remarkably with the variation of the solar wind dynamic pressure.

关键词： solar wind dynamic pressure shrinkage of magnetosphere storm sudden commencement substorm

The management of telecommunications : business solutions to business problems / 2nd ed.

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The management of telecommunications : business solutions to...

Near-Earth bursty bulk flows and AE index

1000年

作者： carr houston h.

来源：畅想之星图书光盘版（南... 评论

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science China(Technological sciences) 2008年第10期51卷 1704-1712页

作者： W BAUMJOhANN M. W. DUNLOP C. carr h. RME space Research Institute Austrian Academy of Sciences Graz Austria space sciences Division Rutherford Appleton Laboratory Chilton Didcot UK Imperial College London United Kingdom Centre d'Etude spatiale des Rayonnements Toulouse France

With the 4-s resolution data of the magnetometer and the ion plasma analyzer on TC-1 from June to November of each year during the period of 2004―2006, we statistically analyzed the occurrence rate of both convective and field-aligned bursty flows (FABFs). A near-Earth bursty bulk flow (NEBBF) occurred during both the quiet time and substorm process. In general, the magnetic field and the plasma density began oscillating with the appearance of the NEBBF associated with a distinct increase of the AE index. The increase of AE index during the NEBBF was more than 100 nT in both quiet time and substorm process. The statistical analysis indicated that the occurrence rates of the FABFs were nearly the same in the dif-ferent stages of the AE index, but the occurrence rate of the NEBBFs was much higher in the growth stage of the AE index, indicating that the NEBBFs were di-rectly related to the growth and expansion phases of the substorm. The observa-tions suggested that the quite large number of BBFs from the mid magnetotail could enter into the near-Earth tail and play important role in triggering the sub-storm onset.

关键词： BBF near-Earth AE index substorm onset