检索结果-南通市图书馆

Unlocking hypoglycemia–associated brain microvascular dysfunction:critical insights from proteomic analysis

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1707-1708页

作者： siva s.V.P.sakamuri Anil sakamuri Department of Chemistry Auburn University at MontgomeryMontgomeryALUSA Vascular Biology Center and Department of Medicine Medical College of Georgia at Augusta UniversityAugustaGAUSA

hypoglycemia-a critical complication linked to worsened brain function in diabetic subjects:hypoglycemia is characterized by a decline in circulatory glucose levels below sta nda rd physiological *** hypoglycemia,classified as level 1 hypoglycemia,is defined by blood glucose levels below 70 mg/dL and can be effectively addressed through carbohydrate *** hypoglycemia,denoted by blood glucose levels less than 54 mg/dL,poses a life-threatening risk if left *** with type 1 and type 2 diabetes undergoing insulin treatment are particularly susceptible to hypoglycemia due to impaired counterregulatory mechanisms.

关键词： impaired intake critical

Influence of soaking time in deep cryogenic treatment on the microstructure and mechanical properties of low-alloy medium-carbon hY-TUF steel

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2016年第6期23卷 658-666页

作者： Ahmad Zare s.R.hosseini Department of Materials Engineering Maleke-ashtar University of Technology

The influence of soaking time in deep cryogenic treatment on the tensile and impact properties of low-alloy medium-carbon hY-TUF steel was investigated in this study. Microstructural studies based on phase distribution mapping by electron backscatter diffraction show that the deep cryogenic process causes a decrease in the content of retained austenite and an increase in the volume fraction of η-carbide with increasing soaking time up to 48 h. The decrease in the content of retained austenite from ~1.23vol% to 0.48vol% suggests an isothermal martensitic transformation at 77 K. The η-type precipitates formed in deep cryogenic-treated martensite over 48 h have the hirotsu and Nagakura orientation relation with the martensitic matrix. Furthermore, a high coherency between η-carbide and the martensitic matrix is observed by high-resolution transmission electron microscopy. The variations in macrohardness, yield strength, ultimate tensile strength, and ductility with soaking time in the deep cryogenic process show a peak/plateau trend.

关键词： low alloy steel medium carbon steel cryogenic treatment microstructure mechanical properties fractography

Regulator of G protein signaling 6 mediates exercise-induced recovery of hippocampal neurogenesis,learning,and memory in a mouse model of Alzheimer’s disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2969-2981页

作者： Mackenzie M.spicer Jianqi Yang Daniel Fu Alison N.DeVore Marisol Lauffer Nilufer s.Atasoy Deniz Atasoy Rory A.Fisher Department of Neuroscience and Pharmacology University of Iowa Carver College of MedicineIowa CityIAUSA Iowa Neuroscience Institute University of Iowa Carver College of MedicineIowa CityIAUSA Interdisciplinary Graduate Program in Molecular Medicine University of Iowa Carver College of MedicineIowa CityIAUSA Neural Circuits and Behavior Core University of Iowa Carver College of MedicineIowa CityIAUSA

hippocampal neuronal loss causes cognitive dysfunction in Alzheimer’s *** hippocampal neurogenesis is reduced in patients with Alzheimer’s *** stimulates adult hippocampal neurogenesis in rodents and improves memory and slows cognitive decline in patients with Alzheimer’s ***,the molecular pathways for exercise-induced adult hippocampal neurogenesis and improved cognition in Alzheimer’s disease are poorly ***,regulator of G protein signaling 6(RGs6)was identified as the mediator of voluntary running-induced adult hippocampal neurogenesis in ***,we generated novel RGs6fl/fl;APP_(sWE) mice and used retroviral approaches to examine the impact of RGs6 deletion from dentate gyrus neuronal progenitor cells on voluntary running-induced adult hippocampal neurogenesis and cognition in an amyloid-based Alzheimer’s disease mouse *** found that voluntary running in APP_(sWE) mice restored their hippocampal cognitive impairments to that of control *** cognitive rescue was abolished by RGs6 deletion in dentate gyrus neuronal progenitor cells,which also abolished running-mediated increases in adult hippocampal *** hippocampal neurogenesis was reduced in sedentary APP_(sWE) mice versus control mice,with basal adult hippocampal neurogenesis reduced by RGs6 deletion in dentate gyrus neural precursor ***6 was expressed in neurons within the dentate gyrus of patients with Alzheimer’s disease with significant loss of these RGs6-expressing ***,RGs6 mediated voluntary running-induced rescue of impaired cognition and adult hippocampal neurogenesis in APP_(sWE) mice,identifying RGs6 in dentate gyrus neural precursor cells as a possible therapeutic target in Alzheimer’s disease.

关键词： adult hippocampal neurogenesis Alzheimer’s disease dentate gyrus exercise learning/memory neural precursor cells regulator of G protein signaling 6(RGs6)

A glance on the effects of temperature on axisymmetric dynamic behavior of multiwall carbon nanotubes

在线全文

学校读者我要写书评

暂无评论

Acta Mechanica sinica 2012年第3期28卷 720-728页

作者： s.T.Talebian M.Tahani M.h.Abolbashari s.M.hosseini Department of Mechanical Engineering Faculty of EngineeringFerdowsi University of Mashhad Department of Mechanical Engineering Lean Production Engineering Research CenterFerdowsi University of Mashhad Department of Industrial Engineering Faculty of EngineeringFerdowsi University of Mashhad

In this paper the effects of temperature on the radial breathing modes （RBMs） and radial wave propaga- tion in multiwall carbon nanotubes （MWCNTs） are inves- tigated using a continuum model of multiple elastic isotropic shells. The van der Waals forces between tubes are simulated as a nonlinear function of interlayer spacing of MWCNTs. The governing equations are solved using a finite element method. A wide range of innermost radius-to-thickness ratio of MWCNTs is considered to enhance the investigation. The presented solution is verified by comparing the results with those reported in the literature. The effects of temperature on the van der Waals interaction coefficient between layers of MWCNTs are examined. It is found that the variation of the van der Waals interaction coefficient at high temperature is sensible. subsequently, variations of RBM frequencies and radial wave propagation in MWCNTs with temperatures up to 1 600 K are illustrated. It is shown that the thick MWC- NTs are more sensible to temperature than the thin ones.

关键词： Multiwall carbon nanotube Radial wave propa-gation. Radial breathing modes - van der Waals force. Ther-mal effects

A mild, configurable, flexible CoNi-LDh（v）/Zn battery based on h-vacancy-induced reversible Zn2+ intercalation

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 498-508页

作者： Xinyue Cheng Dingsheng Wu hao Gao Qingqing Wang Pengfei Lv sam s.Yoon Qufu Wei Key Laboratory of Eco-textiles Ministry of Education Jiangnan University school of Mechanical Engineering Korea University

Flexible Zn-based batteries have attracted increasing research interest as essential components of wearable energy storage ***,the advancement of flexible aqueous Zn-based batteries based on Co-Ni layered double hydroxide （CoNi-LDh） as the cathode material is hampered by their poor cycling stability and the corrosiveness of alkaline ***,CoNi-LDh nanosheets enriched with h vacancies (CoNi-LDh（v）) were constructed on a flexible carbon cloth （CC） substrate via electrochemical deposition and *** Zn-based battery comprising CoNi-LDh（v）@CC as the cathode exhibited highly reversible conversion reactions and stable operation in 3 M ZnsO4electrolyte （ph=4）.The battery delivered an excellent specific capacity (225 mA h g-1,0.26 mA h cm-2),acceptable cycling stability（53.9%,900 cycles）,and high discharging *** abundant h vacancies served as active sites for the reversible intercalation of Zn2+and the extravasation of NO3-generated channels and space for Zn2+transport and storage,together enabling an excellent Zn2+storage ***,a sandwich-structured solid-state CoNi-LDh（v）@CC//Zn@CC battery was fabricated and was found to exhibit a noteworthy electrochemical performance and mechanical *** a proof of concept,the unencapsulated battery powered a digital watch under various deformation conditions and operated stably for 80 ***,the flexible battery displayed outstanding customizability,maintaining an open-circuit voltage of 1.42 V even after being cut *** proposed engineering strategy contributes to the realization of textiles with truly wearable energy-storage devices.

关键词： CoNi/Zn battery h vacancies Mild aqueous electrolyte Tailorable battery Wearable energy storage device

smart computing approach for design and scale-up of conical spouted beds with open-sided draft tubes

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Particuology 2021年第2期19卷 179-190页

作者： M.Karimia B.Vaferi s.h.hosseini M.Olazar s.Rashidi Laboratory of separation and Reaction Engineering(LsRE) Associate Laboratory(LSRE/LCM)Department of Chemical EngineeringFaculty of EngineeringUniversity of PortoRua Dr.Roberto FriasS/N4099-002 PortoPortugal Department of Advanced Calculations ChemicalPetroleumand Polymer Engineering Research CenterShiraz BranchIslamic Azad UniversityShirazIran Department of Chemical Engineering Ilam UniversityIlam 69315-516Iran Department of Chemical Engineering University of the Basque Country UPV/EHUP.O.Box 644E48080 BilbaoSpain Department of Petroleum Engineering Omidiyeh BranchIslamic Azad UniversityOmidiyehIran

Open-sided draft tubes provide an optimal gas distribution through a cross flow pattern between the spout and the annulus in conical spouted *** design,optimization,control,and scale-up of the spouted beds require precise information on operating and peak pressure *** this study,a multi-layer perceptron(MLP)neural network was employed for accurate prediction of these hydrodynamic characteristics.A relatively huge number of experiments were accomplished and the most influential dimensionless groups were extracted using the Buckingham-pi ***,the dimensionless groups were used for developing the MLP model for simultaneous estimation of operating and peak pressure *** iterative constructive technique confirmed that 4-14-2 is the best structure for the MLP model in terms of absolute average relative deviation(AARD%),mean square error(MsE),and regression coefficient(R^(2)).The developed MLP approach has an excellent capacity to predict the transformed operating(MsE=0.00039,AARD%=1.30,and R^(2)=0.76099)and peak(MsE=0.22933,AARD%=11.88,and R2=0.89867)pressure drops.

关键词： Conical spouted beds Open-sided draft tubes Operating pressure drops Peak pressure drop smart modeling Design guidelines

Cu-（B4C）p metal matrix composites processed by accumulative rollbonding

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Progress in Natural science:Materials International 2016年第6期26卷 613-620页

作者： s.Mansourzadeh M.hosseini E.salahinejad A.h.Yaghtin Department of Materials science and Engineering College of Chemical and Metallurgical EngineeringShiraz BranchIslamic Azad University Department of Materials science and Engineering School of EngineeringShiraz University Faculty of Materials science and Engineering K.N.Toosi University of Technology

In this study, Cu/B4C metal matrix composites were prepared by accumulative roll-bonding（ARB）. The microstructure of the processed samples was characterized by TEM, sEM and optical microscopy. The microhardness, uniaxial tensile and four-point probe tests were carried out to evaluate the mechanical properties and electrical resistivity of the ARBed monolithic and composite samples. The results showed that the reinforcement distribution was improved by increasing ARB cycles, which was quantitatively confirmed by some models. Based on TEM observations, the formation of an ultrafine grained structure in the composite matrix was also approved. It was shown that with increasing ARB cycles, the microhardness and tensile strength of the monolithic Cu samples were enhanced up to the 3rd cycle and then saturated, but the microhardness and tensile strength of the composites showed an increasing trend to the last cycle. Apart from a substantial improvement in the mechanical properties of the Cu/B4C composites, a minor decrement in electrical conductivity was detected after six ARB cycles.

关键词： Electron microscopy Mechanical characterization Composites

Impact of Zika virus non-structural protein mutations on hippocampal damage

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2307-2308页

作者： Larissa M.G.Cassiano Roney s.Coimbra Neurogenômica/Imunopatologia Instituto RenéRachouFiocruzBelo HorizonteBrazil Departamento de Bioquímica e Imunologia Instituto de Ciências BiológicasUniversidade Federal de Minas GeraisBelo HorizonteBrazil

The Zika virus(ZIKV),a member of the Flaviviridae family,attracted worldwide attention for its connection to severe neurological effects,notably microcephaly in newborns,first reported during the 2015 epidemic in ***,its impact goes beyond fetal and neonatal abnormalities,also affecting the central nervous system(CNs)in both children and adults,leading to enduring cognitive and behavioral impairments.

关键词： damage fetal neonatal

Comparative analysis of different static mixers performance by CFD technique:An innovative mixer

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2020年第3期28卷 672-684页

作者： M.M.haddadi s.h.hosseini D.Rashtchian Martin Olazar Chemical and Petroleum Engineering Department Sharif University of TechnologyTehranIran Department of Chemical Engineering.Ilam University llam 69315-516Iran Department of Chemical Engineering University of the Basque Country(UPV/EHU)Sarriena s/nLeioaSpain

The flow and mixing behavior of two miscible liquids has been studied in an innovative static mixer by using CFD,with Reynolds numbers ranging from 20 to *** performance of the new mixer is compared with those of Kenics,sMX,and Komax static *** pressure drop ratio(Z-factor),coefficient of variation(CoV),and extensional efficiency(α)features have been used to evaluate power consumption,distributive mixing,and dispersive mixing performances,respectively,in all *** model is firstly validated based on experimental data measured for the pressure drop ratio and the coefficient of *** results are consistent with measured data and those obtained by available correlations in the *** new mixer shows a superior mixing performance compared to the other mixers.

关键词： CFD New static mixer Coefficient of variation Pressure drop ratio