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A rat model of multicompartmental traumatic injury and hemorrhagic shock induces bone marrow dysfunction and profound anemia

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Animal Models and experimental Medicine 2024年第3期7卷 367-376页

作者： Lauren s.Kelly Jennifer A.Munley erick e.Pons Kolenkode B.Kannan elizabeth M.Whitley Letitia e.Bible Philip A.efron Alicia M.Mohr Department of surgery and sepsis and Critical Illness Research Center University of Florida College of MedicineGainesvilleFloridaUSA Pathogenesis LLCGainesvilleFloridaUSA

Background:severe trauma is associated with systemic inflammation and organ *** rodent trauma models are the mainstay of postinjury research but have been criticized for not fully replicating severe human *** aim of this study was to create a rat model of multicompartmental injury which recreates profound traumatic ***:Male sprague-Dawley rats were subjected to unilateral lung contusion and hemorrhagic shock(LCHs),multicompartmental polytrauma(PT)(unilateral lung contusion,hemorrhagic shock,cecectomy,bifemoral pseudofracture),or na?ve ***,plasma toll-l ike receptor 4(TLR4),hemoglobin,spleen to body weight ratio,bone marrow(BM)erythroid progenitor(CFU-GeMM,BFU-e,and CFU-e)growth,plasma granulocyte colony-stimulating factor(G-CsF)and right lung histologic injury were assessed on day 7,with significance defined as p valuesesults:Polytrauma resulted in markedly more profound inhibition of weight gain compared to LCHs(p=0.0002)along with elevated plasma TLR4(per hemoglobin(penlarged spleen to body weight ratios(p=0.004).Both LCHs and PT demonstrated suppression of CFU-e and BFU-e growth compared to naive(psma G-CsF was elevated in PT compared to both na?ve and LCHs(ps and PT demonstrated significant histologic right lung injury with poor alveolar wall integrity and interstitial ***:Multicompartmental injury as described here establishes a reproducible model of multicompartmental injury with worsened anemia,splenic tissue enlargement,weight loss,and increased inflammatory activity compared to a less severe *** may serve as a more effective model to recreate profound traumatic injury to replicate the human inflammatory response postinjury.

关键词： anemia i nflammation polytrauma pseudofracture shock

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Influence of Methane-Hydrogen Mixture Characteristics on Compressor Vibrations

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Fluid Dynamics & Materials Processing 2024年第5期20卷 1031-1043页

作者： Vladimir Ya.Modorskii Ivan e.Cherepanov High Performance Computing Center Perm National Research Polytechnic UniversityPerm614990Russia

A transition to clean hydrogen energy will not be possible until the issues related to its production, transportation,storage, etc., are adequately resolved. Currently, however, it is possible to use methane-hydrogen *** gas can be transported using a pipeline system with the required pressure being maintained by gascompression stations. This method, however, is affected by some problems too. Compressors emergency stopscan be induced by vibrations because in some cases, mechanical methods are not able to reduce the vibrationamplitude. As an example, it is known that a gas-dynamic flow effect in labyrinth seals can lead to increasedvibrations. This paper presents the numerical simulation of rotor oscillations taking into account a gas-dynamicload. The influence of a transported mixture on the oscillatory process is investigated. Mixtures consisting ofmethane and hydrogen in various proportions and an air mixture are considered. The results are discussed forvarious operating pressures and include the rotor motion trajectories and oscillation frequency spectra obtainednumerically. It is shown that the gas mixture composition has a significant effect on the oscillations and theiroccurrence. Hydrogen as a working fluid reduces the vibration amplitude. Operating a compressor with hydrogenleads to a decrease in the resonant frequency, bringing it closer to the operating one. However, the operatingpressure at which maximum oscillations are observed depends slightly on the gas mixture composition.

关键词： seal stabilities vibration FsI CFD multiphase flows hydrogen

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Artificial intelligence meets body sense: task-driven neural networks reveal computational principles of the proprioceptive pathway

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signal Transduction and Targeted Therapy 2024年第8期9卷 3147-3149页

作者： Leonard e.van Dyck Frank Bremmer Katharina Dobs Department of Psychology Justus Liebig University GiessenGiessenGermany Max Planck Institute for Human Cognitive and Brain sciences LeipzigGermany Center for Mind Brain and BehaviorUniversities of MarburgGiessenand DarmstadtMarburgGermany Department of Neurophysics Philipps-Universitat MarburgMarburgGermany

In a recent study published in Cell,Marin Vargas and Bisi et al.1 present an innovative approach to unravel the computational principles underlying proprioceptive processing in non-human *** findings showcase the utility of task-driven modeling in advancing neuroscience and offer translational potential by providing seminal insights into the goals and mechanisms by which the brain encodes body position and movements.

关键词： networks neural principles

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A Proposed Feature selection Particle swarm Optimization Adaptation for Intelligent Logistics--A supply Chain Backlog elimination Framework

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Computers, Materials & Continua 2024年第6期79卷 4081-4105页

作者： Yasser Hachaichi Ayman e.Khedr Amira M.Idrees College of Computing and Information Technology at Khulais Department of Information SystemsUniversity of JeddahJeddah21959Saudi Arabia Faculty of Computers and Information Technology Future University in EgyptCairo11835Egypt

The diversity of data sources resulted in seeking effective manipulation and *** challenge that arises from the increasing dimensionality has a negative effect on the computation performance,efficiency,and stability of *** of the most successful optimization algorithms is Particle swarm Optimization(PsO)which has proved its effectiveness in exploring the highest influencing features in the search space based on its fast convergence and the ability to utilize a small set of parameters in the search *** research proposes an effective enhancement of PsO that tackles the challenge of randomness search which directly enhances PsO *** the other hand,this research proposes a generic intelligent framework for early prediction of orders delay and eliminate orders backlogs which could be considered as an efficient potential solution for raising the supply chain *** proposed adapted algorithm has been applied to a supply chain dataset which minimized the features set from twenty-one features to ten significant *** confirm the proposed algorithm results,the updated data has been examined by eight of the well-known classification algorithms which reached a minimum accuracy percentage equal to 94.3%for random forest and a maximum of 99.0 for Naïve ***,the proposed algorithm adaptation has been compared with other proposed adaptations of PsO from the literature over different *** proposed PsO adaptation reached a higher accuracy compared with the literature ranging from 97.8 to 99.36 which also proved the advancement of the current research.

关键词： Optimization particle swarm optimization algorithm feature selection logistics supply chain management backlogs

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On B(5,20)2-Groups

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Algebra Colloquium 2024年第3期31卷 429-440页

作者： e.A.Alhassan Y.L.Tan Y.Li school of Mathematical sciences Jiangsu UniversityZhenjiangJiangsu 212013China Department of Mathematics Brock UniversitySt.CatharinesOntario L2S 3A1Canada

A finite group G is said to be a B(n,k)group if for any n-element subset[a_(1),…,a_(n)]of G,|{a_(i)a_(j)|1≤i,j≤n}|≤*** is of interest to characterize the structure of B(n,k)groups for n(n+1)/2≤k≤n^(2)-*** B(5,k)groups for 15≤k≤19 have been investigated by several *** this paper,we give a complete characterization of B(5,20)2-groups by showing there are five classes of such groups which are nontrivial and nonabelian.

关键词： B(n,k)groups small squaring property central extension GAP

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Juvenile survival curves in a solitary ground squirrel with a prolonged hibernation:effects of individual characteristics,environment,and maternal investment

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Current Zoology 2024年第1期70卷 13-23页

作者： Nina A.Vasilieva Liudmila e savinetskaya Andrey V.Tchabovsky A.N.severtsov Institute of ecology and evolution Russian Academy of SciencesMoscow 119071Russia

Juvenile survival is a key life-history influence on population dynamics and adaptive *** analyzed the effects of individual chara-cteristics,early environment,and maternal investment on juvenile survival in a large solitary hibernating rodent-yellow ground squirrel spermophilus fulvus using Cox mixed-effects *** 48%of weaned pups survived to dispersal and 17%survived to *** life expectancy was primarily determined by individual characteristics and,to a lesser extent,by the early *** strongest and pos-itive predictor of juvenile survival was body mass which crucially affected mortality immediately after *** suffered higher mortality than females after the onset of dispersal;however,the overall difference between sexes was partly masked by high rates of mortality in the first days after emergence in both *** emerged juveniles had lower life expectancy than the earliest *** overall effect of local juvenile density was *** lactation did not enhance juvenile survival:Pups nursed longer survived shorter than the young nursed for a shorter *** findings support the hypothesis that females of *** cannot effectively regulate maternal expenditures to mitigate the effects of unfavorable conditions on their *** strategy to deal with seasonal time constraints on life history in female *** suggests an early termination of maternal care at the cost of juvenile quality and *** female reproductive strategy corresponds to a"fast-solitary"life of folivorous desert-dwelling *** and other solitary ground squirrels with prolonged hibernation.

关键词： early-life conditions ground squirrels hibernation juvenile mortality maternal investment survival curves

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Could mammalian inorganic polyphosphate be a crucial signaling molecule in neurological disorders?

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Neural Regeneration Research 2024年第4期19卷 701-702页

作者： Renata Torres Da Costa Maria e.solesio Rutgers University Department of BiologyCamdenNJUSA

since the early stages of life on earth,cellular metabolism has evolved to adapt to fluctuations in nutrient and oxygen *** this context,mammals,which are probably the organisms that show one of the highest levels of metabolic complexity,have developed an elegant system that uses constant and rechargeable energy sources of modulate their *** homeostasis is especially important in the central nervous system,as neurons and other cells in the brain are highly susceptible to fluctuations in nutrients and oxygen availability.

关键词： metabolism homeostasis neurological

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Commentary on “Does light-intensity physical activity moderate the relationship between sitting time and adiposity markers in adolescents?”

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Journal of sport and Health science 2024年第4期13卷 453-454页

作者： Barbara e.Ainsworth Amanda M.Ferland school of exercise and Health Shanghai University of SportShanghai 200433China Department of Orthopedics Tongji UniversityShanghai 200092China

In the september 2022 issue of the Journal of sport and Health science,Ayala et al.1 published results from a cross-sectional study where they tested the hypothesis that light intensity physical activity(LIPA,1.6-2.9 metabolic equivalents(MeTs))moderates the relationship between sitting time and adiposity in 219 Australian adolescents aged 14±1.6 years(mean±sD).

关键词： metabolic light

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exploring the effects of anthropogenic disturbance on predator inspection activity in Trinidadian guppies

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Current Zoology 2024年第1期70卷 109-111页

作者： Alix J.P Brusseau Laurence e.A.Feyten Adam L.Crane Grant e.Brown Department of Biology Concordia UniversityMontrealQCH4B 1R6Canada Department of Biomedical sciences WCVMUniversity of SaskatchewanSaskatoonSKCanada

Prey animals are often faced with uncertainty due to having imperfect information regarding current local conditions,including predation risks and the availability of reliable foraging opportunities(Dall 2010).As this uncertainty increases,the probability of making costly behavioral errors also increases,leading to more risk averse behavioral tactics(Feyten et al.2019).For example,Trinidadian guppies Poecilia reticulata are far more risk averse when faced with multiple unknown sources of risk assessment information than when faced with a mix of known and unknown cues(Feyten et al.2019).Prey can reduce uncertainty by gathering and integrating private and social information regarding current risk levels within microhabitats(Dall 2010;Munoz and Blumstein 2012).

关键词： human disturbance information availability information reliability predator-prey interactions risk assessment uncertainty

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Approximate synchronization of Multi-Agent systems over Finite Fields

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Journal of systems science & Complexity 2024年第4期37卷 1561-1580页

作者： YU Miao FeNG Jun-e XIA Jianwei FU shihua sHeN Hao school of Mathematical sciences Liaocheng UniversityLiaocheng 252059China school of Mathematics Shandong UniversityJinan 250100China school of electrical and Information engineering Anhui University of TechnologyMaanshan 243002China

In this paper,the approximate synchronization of leader-follower multiagent systems(MAss) over finite fields is studied in regard to local and global ***,the approximately synchronous state set(Asss) is ***,combined with Asss and transient periods,some criteria for the local and global approximate synchronization of systems are ***,the algorithms for calculating the maximum approximately synchronous basin(MAsB) and the maximum control invariant set(MCIs) are ***,the global approximate synchronization of the system is achieved by designing the state feedback control,and a design algorithm of the controller using the truth matrix method is ***,the results of approximate synchronization are degenerated to complete ***,two examples are shown to demonstrate the results of this paper.

关键词： Approximate synchronization finite field multiagent system semi-tensor product state feedback control

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