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Detection of diabetic retinopathy in its early stages using textural features of optical coherence tomography angiography

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Journal of Innovative Optical Health sciences 2022年第1期15卷 156-165页

作者： W.Gao B.Li s.chen Y.shi P.Lin O.O.Myakinin V.P.Zakharov school of safety Engineering Ningbo University of Technology Ningbo P.R.China Department of Ophthalmology Ningbo First Hospital NingboP.R.China Department of Laser and Biotechnical systems samara University SamaraRussian Federation

The aim of this study is to detect whether the quantitative textural features of optical coherencetomography angiography (OCTA) images can be used to detect the eyes in the early stage ofdiabetic retinopathy (DR) from eyes with diabetes and no DR (NDR). Textural features includingfractal dimension, contrast, correlation, entropy, energy, and homogeneity were calculatedfrom the OCTA images. The student's t-test was performed to identify the textural featuresthat can be able to detect DR in the early stage. The area under the receiver operating characteristic(AUROC) curves, sensitivity, and specicity were calculated between the study groups.Our results indicated that the fractal dimension in ICP and sVP and the correlation in sVCshowed the statistical signicance between mild NPDR patients and NDR patients. The ROCanalysis results showed that the AUROC of the fractal dimension in ICP was 0.736 with 0.773sensitivity and 0.700 specicity. The cuto® point in ICP was 2.616. The OCTA-based fractaldimension was able to discriminate diabetic eyes with early retinopathy from healthy and NDRwith higher sensitivity and specicity. The OCTA-based correlation showed the power to differentiatethe mild NPDR eyes from the normal healthy and diabetic eyes. These results suggestthat texture-based features of OCTA have the potential to assist in the assessment of therapeuticinterventions to prevent early DR in diabetic subjects.

关键词： Optical coherence tomography angiography texture fractal dimension diabetic retinopathy

Dynamic mechanical properties,deformation and damage mechanisms of eutectic high-entropy alloy AlCoCrFeNi_(2.1)under plate impact

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Journal of Materials science & Technology 2023年第3期134卷 178-188页

作者： s.P.Zhao Z.D.Feng L.X.Li X.J.Zhao L.Lu s.chen N.B.Zhang Y.Cai s.N.Luo The Peac Institute of Multiscale sciences ChengduChina Key Laboratory of Advanced Technologies of Materials Ministry of EducationSouthwest Jiaotong UniversityChengduChina

shock compression and spallation of a eutectic high-entropy alloy(HEA)AlCoCrFeNi_(2.1)with lamellar structure are investigated via plate impact loading with free-surface velocity measurements.The as-cast and postmortem samples are characterized with transmission electron microscopy,electron back-scatter diffraction and scanning electron microscopy.An accurate Hugoniot equation of state is determined.Af-ter shock compression to∼12 GPa,both the L1_(2)and B_(2)phases retain their ordered structures.Dense dislocations in the{111}slip planes,stacking faults and deformation twins are found in the L1_(2)phase,along with fewer dislocations in the{110}slip bands in the B(2)phase.shock-induced deformation twin-ning within the L1_(2)phase of this HEA is observed as a new deformation mechanism under various load-ing conditions.For spallation,both ductile and brittle damage modes are observed.The micro voids and cracks prefer to nucleate at the phase boundaries chiefly,then in the B(2)phase.Under similar shock stress,the spall strength of AlCoCrFeNi_(2.1)HEA is about 40%higher than those of other reported dual-phase HEAs due to the high stability of its semi-coherent phase boundaries.

关键词： High-entropy alloy Hugoniot spall damage Microstructure

shock compression and spallation damage of high-entropy alloy Al_(0.1)CoCrFeNi

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Journal of Materials science & Technology 2022年第33期128卷 1-9页

作者： N.B.Zhang J.Xu Z.D.Feng Y.F.sun J.Y.Huang X.J.Zhao X.H.Yao s.chen L.Lu s.N.Luo Key Laboratory of Advanced Technologies of Materials Ministry of EducationSouthwest Jiaotong UniversityChengdu 610031China The Peac Institute of Multiscale sciences Chengdu 610031China Department of Engineering Mechanics South China University of TechnologyGuangzhou 510641China

shock compression and spallation damage of a face-center cubic phase high-entropy alloy(HEA)Al_(0.1)CoCrFeNi were investigated via plate impact experiments along with free surface velocity measurements.Postmortem samples were characterized with transmission electron microscopy and electron backscatter diffraction.The Hugoniot equation of state and spall strength at different impact strengths were determined.There exists a power-law relation between spall strength and strain rate.The spall strength of Al_(0.1)CoCrFeNi HEA is about 50%higher than those of previously studied HEAs and comparable to those widely applied structural stainless steels at the same shock stress.Dislocation glide and stacking faults are the important deformation mechanisms in the Al_(0.1)CoCrFeNi HEA.Nanotwins are only observed at high shock stress.Damage in the Al_(0.1)CoCrFeNi HEA is ductile in nature.Voids are nucleated preferentially in grain interiors,and the intragranular voids show a strong dependence on grain boundary misorientation and peak stress.

关键词： Al_(0.1)CoCrFeNi High-entropy alloy Hugoniot spall damage Microstructure

Antiplane sH-deformations near a surface rigid foundation above a subsurface rigid circular tunnel

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Earthquake Engineering and Engineering Vibration 2002年第1期1卷 27-35页

作者： V.W.Lee M.E.Manoogian s.chen Civil & Envir.Eng.Dept. Univ.of Southern CaliforniaLos AngelesCaliforniaU.S.A.Associate Professor Civil Eng.& Envir:sci.Dept. Loyola Marymount Univ.Los AngelesCaliforniaU.S.A.Associate Professor Civil & Envir.Eng.Dept. Univ.of Southern CaliforniaLos AngelesCaliforniaU.S.A. Research Associate

The problem on the dynamic response of a rigid embedded foundation in the presence of an underground rigid tunnel and subjected to excitation of incident anti-plane sH waves is analyzed.By using the exact analytical solution for the two-dimensional sH-wave propagation in and around both the surface rigid foundation and subsurface rigid tunnel,those aspects of the resulting ground motions that are of special interest and importance for seismic resistant design in earthquake analyses have been examined.The computed amplitudes of the resulting periodic ground motions display a very complicated wave-interference between the surface foundation and underground tunnel that lead to observed standing wave patterns, together with abrupt changes in the wave amplitudes and large amplification of the incident motions.

关键词： sH waves wave-interference embedded foundation underground tunnel analytical solution

sTCF conceptual design report (Volume 1): Physics & detector

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Frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov X.C.Ai L.P.An R.Aliberti Q.An X.Z.Bai Y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomyagkov A.Bondar I.Boyko Z.H.Bu F.M.Cai H.Cai J.J.Cao Q.H.Cao X.Cao Z.Cao Q.Chang K.T.Chao D.Y.chen H.chen H.X.chen J.F.chen K.chen L.L.chen P.chen s.L.chen s.M.chen s.chen s.P.chen W.chen X.chen X.F.chen X.R.chen Y.chen Y.Q.chen H.Y.cheng J.cheng s.cheng T.G.cheng J.P.Dai L.Y.Dai X.C.Dai D.Dedovich A.Denig I.Denisenko J.M.Dias D.Z.Ding L.Y.Dong W.H.Dong V.Druzhinin D.s.Du Y.J.Du Z.G.Du L.M.Duan D.Epifanov Y.L.Fan s.s.Fang Z.J.Fang G.Fedotovich C.Q.Feng X.Feng Y.T.Feng J.L.Fu J.Gao Y.N.Gao P.s.Ge C.Q.Geng L.s.Geng A.Gilman L.Gong T.Gong B.Gou W.Gradl J.L.Gu A.Guevara L.C.Gui A.Q.Guo F.K.Guo J.C.Guo J.Guo Y.P.Guo Z.H.Guo A.Guskov K.L.Han L.Han M.Han X.Q.Hao J.B.He s.Q.He X.G.He Y.L.He Z.B.He Z.X.Heng B.L.Hou T.J.Hou Y.R.Hou C.Y.Hu H.M.Hu K.Hu R.J.Hu W.H.Hu X.H.Hu Y.C.Hu J.Hua G.s.Huang J.s.Huang M.Huang Q.Y.Huang W.Q.Huang X.T.Huang X.J.Huang Y.B.Huang Y.s.Huang N.Hüsken V.Ivanov Q.P.Ji J.J.Jia s.Jia Z.K.Jia H.B.Jiang J.Jiang s.Z.Jiang J.B.Jiao Z.Jiao H.J.Jing X.L.Kang X.s.Kang B.C.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin Y.Lei E.Levichev C.H.Li C.Li D.Y.Li F.Li G.Li G.Li H.B.Li H.Li H.N.Li H.J.Li H.L.Li J.M.Li J.Li L.Li L.Li L.Y.Li N.Li P.R.Li R.H.Li s.Li T.Li W.J.Li X.Li X.H.Li X.Q.Li X.H.Li Y.Li Y.Y.Li Z.J.Li H.Liang J.H.Liang Y.T.Liang G.R.Liao L.Z.Liao Y.Liao C.X.Lin D.X.Lin X.s.Lin B.J.Liu C.W.Liu D.Liu F.Liu G.M.Liu H.B.Liu J.Liu J.J.Liu J.B.Liu K.Liu K.Y.Liu K.Liu L.Liu Q.Liu s.B.Liu T.Liu X.Liu Y.W.Liu Y.Liu Y.L.Liu Z.Q.Liu Z.Y.Liu Z.W.Liu I.Logashenko Y.Long C.G.Lu J.X.Lu N.Lu Q.F.Lü Y.Lu Y.Lu Z.Lu P.Lukin F.J.Luo T.Luo X.F.Luo Y.H.Luo H.J.Lyu X.R.Lyu J.P.Ma P.Ma Y.Ma Y.M.Ma F.Maas s.Malde D.Matvienko Z.X.Meng R.Mitchell A.Nefediev Y.Nefedov s.L.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan E.Passemar Y.P.Pei H.P.Peng L.Peng X.Y.Peng X.J.Peng K.Peters s.Pivovarov E.Pyata B.B.Qi Y.Q.Qi W.B.Qian Y.Qian C.F.Qiao J.J.Qin J.J.Qin L.Q.Qin X.s.Qin T.L.Qiu J.Rademacker C.F.Redmer H.Y.sang Anhui University Hefei 230039China Beihang University Beijing 100191China Budker Institute of Nuclear Physics Novosibirsk 630090Russia CAs Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Cavendish Laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom Central China Normal University Wuhan 430079China Central south University Changsha 410083China China University of Geosciences Wuhan 430074China China University of Mining and Technology Xuzhou 221116China École Polytechnique Fédérale de Lausanne(EPFL) LausanneSwitzerland Fudan University Shanghai 200433China Goethe University Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou Institute for Advanced study UCASHangzhou 310024China Hebei Normal University Shijiazhuang 050024China Hebei University Baoding 071002China Hefei University of Technology Hefei 230601China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China High Energy Physics Center Chung-Ang UniversitySeoul 06974Korea Higher school of Economy 11 Pokrovsky Bulvar Moscow 109028Russia Huangshan University Huangshan 245000China Hubei University of Automotive Technology Shiyan 442002China Hunan Normal University Changsha 410081China Hunan University of science and Technology Xiangtan 411201China Hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China Institute of Advanced science Facilities Shenzhen 518107China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China Jilin University Changch

The superτ-charm facility(sTCF)is an electron–positron collider proposed by the Chinese particle physics community.It is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or higher.The sTCF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the BEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the standard Model.The sTCF project in China is under development with an extensive R&D program.This document presents the physics opportunities at the sTCF,describes conceptual designs of the sTCF detector system,and discusses future plans for detector R&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity sTCF detector conceptual design

Office-based facial plastics procedures:Neuromodulators

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World Journal of Otorhinolaryngology-Head and Neck surgery 2023年第3期9卷 220-226页

作者： Andrew J.Johnson David s.chen Department of Otolaryngology-Head&Neck surgery University of Arizona College of MedicineTucsonArizonaUSA

Botulinum toxin is a potent neuromodulator commonly used for cosmetic applications in the clinic.In this article,we reviewed the various formulations of botulinum toxin type A commercially available in the United states,as well as clinical pearls for preprocedural planning,common in-office injections,and management of complications.

关键词： botulinum toxin facial plastics facial wrinkles

Digital Circuits Using sOI Four-Gate Transistor

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Digital Circuits Using SOI Four-Gate Transistor

交叉传播相对论强激光脉冲在等离子体中相互作用及其对电子加热和加速的作用

2006 8th International Conference on solid-state and Integrated Circuit Technology

作者： K.Akarvardar B.Blalock s.chen s.Cristoloveanu P.Gentil M.M.Mojarradi IMEP Minatec 3 Parvis Louis Neel 38016 GrenobleFrance ECE Department The University of TennesseeKnoxvilleTN 37996USA JPL California Institute of TechnologyPasadenaCA 91109USA

Novel G-FET based logic-circuits(adjustable-threshold inverter,real-time reconfigurable logic gates and DRAM cell) are experimentally demonstrated.The independent action of the four gates helps minimize the required t... 详细信息

ISBN: (纸本)1424401607

关键词： digital circuits Logic functions Transistor Device Component silicon-on-insulator gates styrene oxide isomerase Reconfigurable logic

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物理 2004年第6期33卷 400-403页

作者：盛政明 P.Zhang N.saleh s.chen D.Umstadter 中国科学院物理研究所 FOCUs Center

文章介绍了相干交叉传播的相对论强激光在与等离子体相互作用中产生的能量交换、瞬态电子密度调制和激光加速电子 .这些被加速的电子先在交叉光场中被捕获 ,随后又注入到等离子体波中 ,获得进一步的加速 .

关键词：交叉传播相对论强激光瞬态电子密度调制电子加热电子加速能量交换惯性约束聚变

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阿科马盆地低渗透干气藏的特征

国外油气勘探 1993年第2期 143-150页

作者： s.chen R.E.Robbins 刘舒杰

勘探开发策略随着对储层特征的进一步了解而完善。为此目的,本文通过分析七个县域内的75口井,考察了阿科马盆地低渗透气藏的特征。研究区包括阿肯色州的克劳福德县、富兰免林县、洛根县和锡巴斯琴县,以及俄克拉何马州的拉蒂默县、勒弗... 详细信息

勘探开发策略随着对储层特征的进一步了解而完善。为此目的,本文通过分析七个县域内的75口井,考察了阿科马盆地低渗透气藏的特征。研究区包括阿肯色州的克劳福德县、富兰免林县、洛根县和锡巴斯琴县,以及俄克拉何马州的拉蒂默县、勒弗洛尔县和哈斯克尔县。考察的储层特征包括地质背景、储层流体和岩性、地层评价以及开采动态。本文划分了三类储层,即(Ⅰ)较高孔隙度/高渗透率;(Ⅱ)较低孔隙度/低渗透率;(Ⅲ)较高孔隙度/低渗透卑。Ⅲ类储层因砂岩骨架中的双孔隙度系统而最难描述其特征。骨架孔隙系统主要由变化的粒间孔隙度和溶蚀孔隙度组成。如何表示这类储层的特征是本文的主要努力方向。

关键词：低渗透油气藏气藏油藏描述地层评价油气开采动态