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Associations of accelerometry-measured and self-reported physical activity and sedentary behavior with skeletal muscle energetics:The study of Muscle,Mobility and Aging(sOMMA)

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Journal of sport and Health science 2024年第5期13卷 621-630页

作者： Yujia(susanna)Qiao Terri L.blackwell Peggy M.Cawthon Paul M.Coen steven R.Cummings Giovanna Distefano samaneh Farsijani Daniel E.Forman bret H.Goodpaster stephen b.Kritchevsky Theresa Mau Frederico G.s.Toledo Anne b.Newman Nancy W.Glynn Department of Epidemiology School of Public HealthUniversity of PittsburghPittsburghPA 15261USA san Francisco Coordinating Center California Pacific Medical Center Research InstituteSan FranciscoCA 94143USA Department of Epidemiology and biostatistics University of CaliforniaSan FranciscoCA 94143USA Translational Research Institute AdventHealthOrlandoFL 32804USA Department of Medicine(Geriatrics and Cardiology) University of Pittsburghand GeriatricsResearchEducationand Clinical Center(GRECC)VA Pittsburgh Healthcare SystemPittsburghPA 15261USA Department of Internal Medicine Section on Gerontology and Geriatric MedicineWake Forest School of MedicineWinston-SalemNC 27109USA Division of Endocrinology and Metabolism Department of MedicineUniversity of PittsburghPittsburghPA 15261USA

background:skeletal muscle energetics decline with age,and physical activity(PA)has been shown to offset these declines in older ***,many studies reporting these effects were based on self-reported PA or structured exercise ***,we examined the associations of accelerometry-measured and self-reported PA and sedentary behavior(sb)with skeletal muscle energetics and explored the extent to which PA and sedentary behavior would attenuate the associations of age with muscle ***:As part of the study of Muscle,Mobility and Aging,enrolled older adults(n=879),810(age=76.4±5.0 years old,mean±sD;58%women)had maximal muscle oxidative capacity measured ex vivo via high-resolution re spirometry of permeabilized myofibers(maximal oxidative phosphorylation(maxOXPHOs))and in vivo by ^(31)phosphorus magnetic resonance spectroscopy(maximal adenosine triphosphate(ATP_(max))).Accelerometry-measured sedentary behavior,light activity,and moderate-to-vigorous PA(MVPA)were assessed using a wrist-worn ActiGraph GT9X over 7 ***-reported sedentary behavior,MVPA,and all PA were assessed with the Community Healthy Activities Model Program for seniors(CHAMPs)*** regression models with progressive covariate adjustments evaluated the associations of sedentary behavior and PA with muscle energetics,as well as the attenuation of the age/muscle energetics association by MVP A and sedentary *** a sensitivity analysis,we also examined activPAL-measured daily step count and time spent in sedentary behavior and their associations with muscle ***:Every 30 min/day more of ActiGraph-measured MVPA was associated with 0.65 pmol/(s×mg)higher maxOXPHOs and 0.012 mM/s higher ATP_(max)after adjusting for age,site/technician,and sex(ps not associated with maxOXPHOs or ATP_(max).Meanwhile,every 30 min/day spent in ActiGraph-measured sedentary behavior was associated with 0.39 pmol/s×mg lower maxOXPHOs and0.

关键词： Aging Exercise Mitochondria

A novel diurnal and seasonal variation analysis of bTEX in bengaluru urban area

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Research in Cold and Arid Regions 2024年第1期16卷 14-19页

作者： H.N.sowmya M.Dinamani G.P.shivashankara H.K.Ramaraju b.s.surendra Vijaya V.shanbhag R.Prajwal Department of Civil Engineering Dayananda Sagar College of EngineeringBangalore 560078India Department of Chemistry Dayananda Sagar College of EngineeringBangalore 560078India Department of Physics GFGCVijayanagarBengaluru 560040India

In the urban atmosphere of bengaluru, various volatile organic compounds(VOCs), particularly benzene,Toluene, Ethylbenzene, and Xylene(bTEX), have shown an increasing trend in concentration. The present research was conducted during summer and monsoon seasons, focusing on Kadubeesanahalli, a high-traffic area within the bengaluru Metropolitan City. Hourly sample data was collected using a bTEX analyzer(Model GC955-600) and subsequently transformed into daily, monthly, and seasonal values. The study revealed distinct patterns in benzene concentrations. benzene levels were lowest during the early morning hours, specifically from 1:00 *** 7:00 a.m.. Concentrations then increased from 7:00 a.m. to 9:00 a.m. and again from 4:00 p.m. to 11:00 p.m.,corresponding to the morning and evening peak traffic hours. However, between 10:00 a.m. and 4:00 p.m., the concentration decreased due to reduced traffic levels. These diurnal variations in benzene concentration are influenced by meteorological parameters. Comparing the two seasons, higher concentrations of benzene, Ethylbenzene, and MP-xylene were observed during the summer season. This increase is attributed to the elevated temperatures during summer, which promote the vaporization of bTEX compounds. Conversely, lower bTEX concentrations were recorded during the monsoon season due to the wet deposition process. The observed positive correlation(r > 0.5) among bTEX parameters strongly suggests a common source, most likely originating from vehicular emissions.

关键词： bTEX summer variation Meteorological parameters Correlation

Embracing different languages and local differences:Coconstructive patient simulation strengthens host countries’clinical training in psychiatry

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World Journal of Psychiatry 2024年第1期14卷 111-118页

作者： Şafak ErayÇamlı büşra Ece Yavuz Meliha Feyza Gök Idil Yazgan Yanki Yazgan Ayelet brand-Gothelf Doron Gothelf Doron Amsalem Andrés Martin Department of Child and Adolescent Psychiatry Bursa UludağUniversity Faculty of MedicineBursa 16059 Turkey Yale University school of Medicine New HavenCT 06510United States Güzel Günler Clinic Beşiktaş/İstanbul 34335 Turkey Child study Center Yale School of MedicineNew HavenCT 06520United States The Feinberg Child study Center Schneider Children's Medical Center of IsraelTel Aviv UniversityPetach Tikvah 4920235Israel The Child Psychiatry Division Edmond and Lily Safra Children’s HospitalSheba Medical CenterTel HashomerRamat Gan 52561Israel Faculty of Medicine and sagol school of Neuroscience Tel Aviv UniversityTel Aviv 6997801Israel Department of Psychiatry Columbia University Vagelos College of Physicians and SurgeonsNew YorkNY 10032United States

bACKGROUND Global education in psychiatry is heavily influenced by knowledge from Western,high-income countries,which obscures local voices and *** To adapt a human simulation model to psychiatric education in a context that is specific to local languages and *** We conducted an observational study consisting of six human simulation sessions with standardized patients from two host countries,speaking their native languages,and following an adaptation of the co-constructive patient simulation(CCPs)*** local faculty became increasingly familiar with the CCPs approach,they took on the role of facilitators—in their country’s native *** Fifty-three learners participated:19 child and adolescent psychiatry trainees and 3 faculty members in Türkiye(as a group that met online during 3 consecutive months);and 24 trainees and 7 faculty in Israel(divided into 3 groups,in parallel in-person sessions during a single training day).Each of the six cases reflected local realities and clinical challenges,and was associated with specific learning goals identified by each case-writing *** Human simulation has not been fully incorporated into psychiatric education:The creation of immersive clinical experiences and the strengthening of reflective practice are two areas ripe for *** adaptations of CCPs can also strengthen local and regional networks and psychiatric communities of ***,the model can help question and press against hegemonies in psychiatric training that overshadow local expertise.

关键词： Human simulation standardized patients Medical education Psychiatric education Capacity building Local languages

Analyzing the Impact of scene Transitions on Indoor Camera Localization through scene Change Detection in Real-Time

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Intelligent Automation & soft Computing 2024年第3期39卷 417-436页

作者： Muhammad s.Alam Farhan b.Mohamed Ali selamat Faruk Ahmed AKM b.Hossain Department of Emergent Computing School of ComputingUniversiti Teknologi MalaysiaJohor Bahru81310Malaysia Malaysia-Japan International Institute of Technology(MJIIT) Universiti Teknologi MalaysiaKuala Lumpur54100Malaysia Media and Game Innovation Centre of Excellence(MaGICX) Universiti Teknologi MalaysiaJohor Bahru81310Malaysia Department of Engineering Technology University of MemphisMemphisTN38152USA Department of Computer science and Artificial Intelligence College of Computing and Information TechnologyUniversity of BishaBisha61922Saudi Arabia school of Computing Faculty of EngineeringUniversiti Teknologi MalaysiaJohor Bahru81310Malaysia Department of Information system and Cyber security College of Computing and Information TechnologyUniversity of BishaBisha61922Saudi Arabia

Real-time indoor camera localization is a significant problem in indoor robot navigation and surveillance *** scene can change during the image sequence and plays a vital role in the localization performance of robotic applications in terms of accuracy and *** research proposed a real-time indoor camera localization system based on a recurrent neural network that detects scene change during the image *** annotated image dataset trains the proposed system and predicts the camera pose in *** system mainly improved the localization performance of indoor cameras by more accurately predicting the camera *** also recognizes the scene changes during the sequence and evaluates the effects of these *** system achieved high accuracy and real-time *** scene change detection process was performed using visual rhythm and the proposed recurrent deep architecture,which performed camera pose prediction and scene change impact ***,this study proposed a novel real-time localization system for indoor cameras that detects scene changes and shows how they affect localization performance.

关键词： Camera pose estimation indoor camera localization real-time localization scene change detection simultaneous localization and mapping(sLAM)

semi-analytical investigation of heat transfer in a porous convective radiative moving longitudinal fin exposed to magnetic field in the presence of a shape-dependent trihybrid nanofluid

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Applied Mathematics and Mechanics(English Edition) 2024年第1期45卷 197-216页

作者： C.G.PAVITHRA b.J.GIREEsHA M.L.KEERTHI Department of PG studies and Research in Mathematics Kuvempu UniversityShankaraghatta 577451India Department of Mathematics and statistics M.S.Ramaiah University of Applied SciencesBengaluru 560058India

The thermal examination of a non-integer-ordered mobile fin with a magnetism in the presence of a trihybrid nanofluid(Fe_3O_4-Au-Zn-blood) is carried out. Three types of nanoparticles, each having a different shape, are considered. These shapes include spherical(Fe_3O_4), cylindrical(Au), and platelet(Zn) configurations. The combination approach is utilized to evaluate the physical and thermal characteristics of the trihybrid and hybrid nanofluids, excluding the thermal conductivity and dynamic viscosity. These two properties are inferred by means of the interpolation method based on the volume fraction of nanoparticles. The governing equation is transformed into a dimensionless form, and the Adomian decomposition sumudu transform method(ADsTM) is adopted to solve the conundrum of a moving fin immersed in a trihybrid nanofluid. The obtained results agree well with those numerical simulation results, indicating that this research is reliable. The influence of diverse factors on the thermal overview for varying noninteger values of γ is analyzed and presented in graphical representations. Furthermore, the fluctuations in the heat transfer concerning the pertinent parameters are studied. The results show that the heat flux in the presence of the combination of spherical, cylindrical, and platelet nanoparticles is higher than that in the presence of the combination of only spherical and cylindrical nanoparticles. The temperature at the fin tip increases by 0.705 759% when the value of the Peclet number increases by 400%, while decreases by 11.825 13% when the value of the Hartman number increases by 400%.

关键词： convection radiation moving longitudinal fin Adomian decomposition sumudu transform method(ADsTM) trihybrid nanofluid magnetic field

A facile strategy for tuning the density of surface-grafted biomolecules for melt extrusion-based additive manufacturing applications

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bio-Design and Manufacturing 2024年第3期7卷 277-291页

作者： I.A.O.beeren G.Dos santos P.J.Dijkstra C.Mota J.bauer H.Ferreira Rui L.Reis N.Neves s.Camarero-Espinosa M.b.baker L.Moroni Department of Complex Tissue Regeneration MERLN Institute for Technology-Inspired Regenerative MedicineMaastricht University6229 ER MaastrichtThe Netherlands 3b’s Research Group I3Bs–Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal ICVs/3b’s-PT Government Associate Laboratory 4806-909 Braga/GuimarãesPortugal POLYMAT University of the Basque Country UPV/EHU20018 Donostia/San SebastiánSpain IKERbAsQUE Basque Foundation for Science48009 BilbaoSpain

Melt extrusion-based additive manufacturing(ME-AM)is a promising technique to fabricate porous scaffolds for tissue engi-neering ***,most synthetic semicrystalline polymers do not possess the intrinsic biological activity required to control cell *** of biomolecules on polymeric surfaces of AM scaffolds enhances the bioactivity of a construct;however,there are limited strategies available to control the surface ***,we report a strategy to tune the surface density of bioactive groups by blending a low molecular weight poly(ε-caprolactone)5k(PCL5k)containing orthogonally reactive azide groups with an unfunctionalized high molecular weight PCL75k at different *** porous three-dimensional(3D)scaf-folds were then fabricated using a high weight percentage(75 wt.%)of the low molecular weight PCL *** a proof-of-concept test,we prepared films of three different mass ratios of low and high molecular weight polymers with a thermopress and reacted with an alkynated fluorescent model compound on the surface,yielding a density of 201-561 pmol/cm^(2).subsequently,a bone morphogenetic protein 2(bMP-2)-derived peptide was grafted onto the films comprising different blend compositions,and the effect of peptide surface density on the osteogenic differentiation of human mesenchymal stromal cells(hMsCs)was *** two weeks of culturing in a basic medium,cells expressed higher levels of bMP receptor II(bMPRII)on films with the conjugated *** addition,we found that alkaline phosphatase activity was only significantly enhanced on films contain-ing the highest peptide density(i.e.,561 pmol/cm^(2)),indicating the importance of the surface *** together,these results emphasize that the density of surface peptides on cell differentiation must be considered at the cell-material ***,we have presented a viable strategy for ME-AM community that desires to tune the bulk and surface functionality via blending of(m

关键词： Additive manufacturing blending surface functionalization surface density Click chemistry Human

Plasma electrolytic formation and characterization of MnWO_(4)/WO_(3) film heterostructures

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ChemPhysMater

ChemPhysMater 2024年第3期3卷 293-302页

作者： M.s.Vasilyeva I.V.Lukiyanchuk Yu.b.budnikova V.G.Kuryavyi D.H.shlyk G.A.Zverev Department of Chemistry and Materials of Institute of High Technology and Advanced Materials Far Eastern Federal UniversityFEFU CampusVladivostok 690922Russia Institute of Chemistry Far Eastern BranchRussian Academy of SciencesVladivostok 690022Russia

MnWO_(4)/WO_(3) p-n heterojunction films were fabricated using a one-step method consisting of the plasma electrolytic oxidation(PEO)of titanium in homogeneous electrolytes containing paratungstate ions and stable watersoluble EDTA-chelated *** influences of the formation current density and W:Mn molar ratio of the electrolyte,which was varied from 1:2 to 2:1,on the composition,morphology,and optical and photocatalytic properties of the resulting coatings were studied.X-ray diffraction analysis,scanning electron microscopy,energy dispersive X-ray analysis,Raman spectroscopy,and ultraviolet diffuse reflectance spectroscopy were used to characterize the formed *** of the W:Mn ratio of the electrolyte,the coatings contained crystalline t-WO_(3) and m-MnWO_(4).Depending on the formation conditions,the optical band gap energies of the composites varied from 2.63 to 3.01 *** largest absorption red shift and lowest band gap energy were observed in the film composite formed in an electrolyte with W:Mn=2:1,at a current density of 0.2 A cm^(−2).Composites obtained in electrolytes with W:Mn ratios of 2:1 and 1:1 exhibited photocatalytic activity in the degradation of rhodamine C and methyl orange dyes in the presence of 10 mmol L^(–1) H2O_(2) under ultraviolet and visible light *** role of hydrogen peroxide in this dye degradation on PEO-coated composites under light irradiation is discussed.

关键词： Plasma electrolytic oxidation Manganese tungstate Tungsten oxide Titanium Optical properties p-n heterojunction

Fireworks Optimization with Deep Learning-based Arabic Handwritten Characters RecognitionModel

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Computer systems science & Engineering 2024年第5期48卷 1387-1403页

作者： Abdelwahed Motwakel badriyya b.Al-onazi Jaber s.Alzahrani Ayman Yafoz Mahmoud Othman Abu sarwar Zamani Ishfaq Yaseen Amgad Atta Abdelmageed Department of Computer and self Development Prince Sattam bin Abdulaziz UniversityAlKharj16278Saudi Arabia Department of Language Preparation Arabic Language Teaching InstitutePrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Industrial Engineering College of Engineering at AlqunfudahUmm Al-Qura UniversityMakkah24211Saudi Arabia Department of Information systems Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Computer science Faculty of Computers and Information TechnologyFuture University in EgyptNew Cairo11835Egypt

Handwritten character recognition becomes one of the challenging research *** studies were presented for recognizing letters of various *** availability of Arabic handwritten characters databases was *** a quarter of a billion people worldwide write and speak *** historical books and files indicate a vital data set for many Arab nationswritten in ***,Arabic handwritten character recognition(AHCR)has grabbed the attention and has become a difficult topic for pattern recognition and computer vision(CV).Therefore,this study develops fireworks optimizationwith the deep learning-based AHCR(FWODL-AHCR)*** intention of the FWODL-AHCR technique is to recognize the distinct handwritten characters in the Arabic *** initially pre-processes the handwritten images to improve their quality of ***,the RetinaNet-based deep convolutional neural network is applied as a feature extractor to produce feature ***,the deep echo state network(DEsN)model is utilized to classify handwritten ***,the FWO algorithm is exploited as a hyperparameter tuning strategy to boost recognition *** simulations in series were performed to exhibit the enhanced performance of the FWODL-AHCR *** comparison study portrayed the supremacy of the FWODL-AHCR technique over other approaches,with 99.91%and 98.94%on Hijja and AHCD datasets,respectively.

关键词： Arabic language handwritten character recognition deep learning classification parameter tuning

Quasi-static, Poiseuille Flow of Analgesics from an Elastomeric Pump: Theoretical Determination of Infusion Times and Toxicity Conditions

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Journal of biosciences and Medicines 2024年第9期12卷 251-265页

作者： Clare b. Lipscombe Trevor C. Lipscombe Don s. Lemons Division of General surgery Vanderbilt University Medical Center Nashville TN USA Catholic University of America Press Washington DC USA Department of Physics Bethel College North Newton KS USA

background: Elastomeric pumps (elastic balls into which analgesics or antibiotics can be inserted) push medicines through a catheter to a nerve or blood vessel. since elastomeric pumps are small and need no power source, they fit easily into a pocket during infusion, allowing patient mobility. Elastomeric pumps are widely used and widely studied experimentally, but they have well-known problems, such as maintaining reliable flow rates and avoiding toxicity or other peak-and-trough effects. Objectives: Our research objective is to develop a realistic theoretical model of an elastomeric pump, analyze its flow rates, determine its toxicity conditions, and otherwise improve its operation. We believe this is the first such theoretical model of an elastomeric pump consisting of an elastic, medicine-filled ball attached to a horizontal catheter. Method: Our method is to model the system as a quasi-Poiseuille flow driven by the pressure drop generated by the elastic sphere. We construct an engineering model of the pressure exerted by an elastic sphere and match it to a solution of the one-dimensional radial Navier-stokes equation that describes flow through a horizontal, cylindrical tube. Results: Our results are that the model accurately reproduces flow rates obtained in clinical studies. We also discover that the flow rate has an unavoidable maximum, which we call the “toxicity bump”, when the radius of the sphere approaches its terminal, unstretched value—an effect that has been observed experimentally. Conclusions: We conclude that by choosing the properties of an elastomeric pump, the toxicity bump can be restricted to less than 10% of the earlier, relatively constant flow rate. Our model also produces a relation between the length of time that the analgesic fluid infuses and the physical properties of the fluid, of the elastomeric sphere and the tube, and of the blood vessel into which the analgesic infuses. From these, we conclude that elastomeric pumps can be design

关键词： Elastomeric Pump Infusion Therapy bio-Fluids Medical Devices Antibiotic Delivery Analgesic Delivery