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Insecticide resistance in phlebotomine sandflies in southeast Asia with emphasis on the Indian subcontinent

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Infectious Diseases of Poverty 2016年第1期5卷 972-981页

作者： Ramesh C.Dhiman Rajpal s.yadav Author details 1 National Institute of Malaria Research(ICMR) Delhi 110077India Department of Control of Neglected Tropical Diseases World Health OrganizationGenevaSwitzerland

Background:Visceral leishmaniasis,commonly known as kala-azar in India,is a global public health *** southeast Asia,Bangladesh,Bhutan,India,Nepal,sri Lanka and Thailand are endemic for visceral *** role of sandflies as the vector of kala-azar was first confirmed in 1942 in *** resistance in Phlebotomus argentipes Annandale and Brunetti,the vector of kala-azar in the Indian subcontinent,was first reported in 1987 in Bihar,*** article provides a scoping review of the studies undertaken from 1959 to 2015 on insecticide resistance in *** and ***(scopoli),the vectors of visceral and cutaneous leishmaniasis respectively,in southeast Asia,mainly in Bangladesh,India,Nepal and sri ***:studies undertaken in areas of Bihar and West Bengal in India where kala-azar is endemic have reported resistance of *** to DDT,while in non-endemic areas it has been reported to be *** areas of Nepal bordering India,there are indications of resistance to DDT;biochemical resistance has been reported in sri *** laboratory studies have been undertaken in Bangladesh;however,the sandfly vector is reported to be still susceptible to pyrethroids in all kala-azar endemic areas in the aforementioned ***:studies are needed to determine the resistance of sandfly vectors to all available classes of potential insecticides in kala-azar endemic *** is a need to assess the impact of indoor residual spraying with DDT and pyrethroids on the incidence of kala-azar in India where 54 districts remain endemic for the disease,strengthen entomological surveillance capacity,and develop and implement an insecticide management ***-cypermethrin indoor residual spraying has been introduced in 33 kala-azar endemic districts in Bihar state of India in a pilot trial;the outcomes should be used to inform decisions on expanding coverage with alpha-cypermethrin in all remaining endemic districts to achie

关键词： DDT Alpha-cypermethrin Indoor residual spraying Indian subcontinent Insecticide resistance Phlebotomus argentipes Phlebotomus papatasi sandflies Visceral leishmaniasis

Traffic Engineering and Quality of service in Hybrid software Defined Networks

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China Communications 2024年第2期21卷 96-121页

作者： samiullah Mehraban Rajesh Kumar yadav IOT Lab Department of Computer Science&EngineeringDelhi Technological UniversityDelhi 110042India

For Future networks, many research projects have proposed different architectures around the globe;software Defined Network(sDN) architectures, through separating Data and Control Layers, offer a crucial structure for it. With a worldwide view and centralized Control, the sDN network provides flexible and reliable network management that improves network throughput and increases link utilization. In addition, it supports an innovative flow scheduling system to help advance Traffic Engineering(TE). For Medium and large-scale networks migrating directly from a legacy network to an sDN Network seems more complicated & even impossible, as there are High potential challenges, including technical, financial, security, shortage of standards, and quality of service degradation challenges. These challenges cause the birth and pave the ground for Hybrid sDN networks, where sDN devices coexist with traditional network devices. This study explores a Hybrid sDN network’s Traffic Engineering and Quality of services Issues. Quality of service is described by network characteristics such as latency, jitter, loss, bandwidth,and network link utilization, using industry standards and mechanisms in a Hybrid sDN Network. We have organized the related studies in a way that the Quality of service may gain the most benefit from the concept of Hybrid sDN networks using different algorithms and mechanisms: Deep Reinforcement Learning(DRL), Heuristic algorithm, K path partition algorithm, Genetic algorithm, sOTE algorithm, ROAR method, and Routing Optimization with different optimization mechanisms that help to ensure high-quality performance in a Hybrid sDN Network.

关键词： DRL hsDN QoE Qos sDN TE

Gas hydrate saturation from NGHP 02 LWD data in the Mahanadi Basin

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Energy Geoscience

Energy Geoscience 2024年第2期5卷 279-289页

作者： Uma shankar Pradeep Kumar yadav sneha Devi Udham singh yadav Department of Geophysics Institute of ScienceBHUVaranasi221005India Oil and Natural Gas Corporation Ltd. Gas Hydrate Research&Technology Centre(GHRTC)Panvel410221Navi MumbaiIndia

During the Indian National Gas Hydrate Program(NGHP)Expedition 02,Logging-while-drilling(LWD)logs were acquired at three sites(NGHP-02-11,NGHP-02-12,and NGHP-02-13)across the Mahanadi Basin in area *** applied rock physics theory to available sonic velocity logs to know the distribution of gas hydrate at site NGHP-02-11 and *** physics modeling using sonic velocity at well location shows that gas hydrate is distributed mainly within the depth intervals of 150-265 m and 100 -215 mbsf at site NGHP-02-11 and NGHP-02-13,respectively,with an average saturation of about 4%of the pore space and the maximum concentration of about 40%of the pore space at 250 m depth at site NGHP-02-11,and at site NGHP-02-13 an average saturation of about 2%of the pore space and the maximum concentration of about 20%of the pore space at 246 m depth,as gas hydrate is distributed mainly within 100-246 mbsf at this *** of gas hydrate estimated from the electrical resistivity method using density derived porosity and electrical resistivity logs from Archie's empirical formula shows high saturation compared to that from the sonic ***,estimates of hydrate saturation based on sonic P-wave velocity may differ significantly from that based on resistivity,because gas and hydrate have higher resistivity than conductive pore fluid and sonic P-wave velocity shows strong effect on gas hydrate as a small amount of gas reduces the velocity significantly while increasing velocity due to the presence of *** site NGHP-02-11,gas hydrate saturation is in the range of 15%e30%,in two zones between 150-180 and 245-265 *** NGHP-02-012 shows a gas hydrate saturation of 20%e30%in the zone between 100 and 207 *** NGHP-02-13 shows a gas hydrate saturation up to 30%in the zone between 215 and 246 *** observations from rock physics modeling and Archie’s approximation show the gas hydrate concentrations are relatively low(space)at the sites of the

关键词： Mahanadi Basin Gas hydrate sonic log Effective medium modeling Electrical resistivity log Archie’s analysis Gas hydrate saturation

Automated Time Based Multi-Criteria Bug Triage Approach:Developer Working Efficiency and social Network Based Developer Recommendation

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Journal of shanghai Jiaotong university(science) 2024年第3期29卷 566-578页

作者： yadav Asmita sINGH Kumar sandeep Krishna Engineering College Ghaziabad 201007India JIIT Noida 201309India

In software development projects,bugs are common *** report bugs in open source *** is a need to develop high quality developer prediction model that considers developer work satisfaction,keep within limited development cost,and improve bug resolution *** address and resolve bug report as soon as possible is the main focus of triager when a new bug is ***,developer work efficiency is an important factor in *** address these issues,a proposed approach recommends a set of developers that could potentially share their knowledge with each other to fix new bug *** proposed approach is called developer working efficiency and social network based developer recommendation(Dwesn).It is a composite model that builds developers'profile by using developer average bug fixing time,work efficiency to fix variety of bugs,as well as the developer's social interactions with other developers.A similarity measure is applied between new bug and bugs in corpus to extract the list of capable developers from the *** proposed approach only selects those developers who are active and less loaded with *** developer with the highest profile score is assigned the *** evaluated our approach on the subset of five large open-source projects including Mozilla,Netbeans,Eclipse,Firefox and OpenOffice,and compared it with the *** results demonstrate that combination of developers'efficiency with their average bug fixing time and interactions in their social network gives good accuracy and efficiently reduces bug tossing *** approach shows an improvement in prediction accuracy,precision,recall,F-score and reduced bug tossing length up to 93.89%,93.12%,93.46%,93.27%and 93.25%,*** proposed approach achieved a 93%hit ratio and 93.34%mean reciprocal rank,indicating that our proposed triager is able to efficiently assign bugs to correct developers.

关键词： open-source repository bug report bug assignment tossing length bug triager developer social network developer recommendation

Modulatory role of plant-derived metabolites on host-microbiota interactions:personalized therapeutics outlook

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BIOCELL 2024年第8期48卷 1127-1143页

作者： POOJA yadav NAR sINGH CHAUHAN Department of Biochemistry Maharshi Dayanand University RohtakRohtakHaryanaIndia

A diverse array of microbes in and on the human body constitute the *** micro-residents continuously interact with the human host through the language of metabolites to dictate the host’s physiology in health and *** biotic and abiotic component ensuring a balanced host-microbiota interaction are potential microbiome therapeutic agents to overcome human *** metabolites are continually being used to treat various *** metabolites target the host’s metabolic machinery and host-gut microbiota interactions to overcome human *** the paramount therapeutic significance of the factors affecting host-microbiota interactions,a comprehensive overview of the modulatory role of plant-derived metabolites in host-microbiota interactions is *** current review puts an effort into comprehending the role of medicinal plants in gut microbiota modulation to mitigate various human *** would develop a holistic understanding of hostmicrobiota interactions and the role of effectors in health and diseases.

关键词： Microbiome therapeutics Human gut microbiota Host-microbiota interactions Personalized therapeutics Plant metabolites Human health and diseases

Progress in metal oxide-based electrocatalysts for sustainable water splitting

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Materials Reports(Energy) 2024年第3期4卷 19-34页

作者： Aasiya s.Jamadar Rohit sutar susmita Patil Reshma Khandekar Jyotiprakash B.yadav Vacuum Techniques and Thin Film Laboratory USICShivaji UniversityKolhapur416004MaharashtraIndia

Metal oxide-based electrocatalysts are promising alternatives to platinum group metals for water splitting due to their low cost,abundant raw materials,and impressive *** review covers recent progress in various metal oxides tailored for hydrogen and oxygen evolution reactions,discussing their crystal structure,composition,and surface modification influence on *** like surface engineering,doping,and nanostructuring are evaluated for enhancing catalytic activity and *** key considerations for commercialization are highlighted,emphasizing ongoing research,innovation,and future scope to drive widespread adoption of water-splitting technology for a cleaner and sustainable future.

关键词： Metal oxide HER OER Electrocatalyst Overall water spilling

Novel succinoylated carboxymethyl guar gum nanocarriers of glimepiride for controlling type-2 diabetes

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Medicine in Novel Technology and Devices 2024年第2期22卷 133-139页

作者： Harsh yadav Biswajit Maji sabyasachi Maiti Department of Pharmacy Indira Gandhi National Tribal UniversityAmarkantakMadhya PradeshIndia Department of Chemistry Indira Gandhi National Tribal UniversityAmarkantakMadhya PradeshIndia

In this study,guar gum(GG)was chemically modified to its carboxymethyl derivative,which was then esterified with octenyl succinic anhydride(OsA)using a nucleophilic catalyst 4-dimethylaminopyridine(DMAP)to render the derivative amphiphilic *** carboxymethyl guar gum(CMGG)and succinoylated CMGG was characterized using Fourier transform infrared spectroscopy(FTIR)*** amphiphilic CMGG synthesized using DMAP/OsA ratio of 0.5:1(CMGGOsA-I),was found to be *** amphiphilic guar gum self-assembled in water to form nanocarriers with mean diameter of 430 nm and zeta potential of19.0 *** electron microscope(TEM)image showed spherical nature of the developed CMGGOsA-I nano*** presence of amphiphilic CMGG,the aqueous solubility of glimepiride was enhanced by about *** nanocarriers released glimepiride in simulated gastrointestinal fluids for a period of more than 24 h,following Higuchi's ***-Peppas modeling of the drug release data revealed that a combination of swelling and diffusion mechanism was operative in the event of drug *** streptozotocin-induced diabetic rat model,the nanocarriers outperformed pure drug suspensions in terms of anti-diabetic activity,which lasted up to 24 ***;the newly synthesized amphiphilic CMGG nanocarriers demonstrated controlled drug release properties and showed promise for controlling type-2 diabetes.

关键词： Guar gum Glimepiride Octenyl succinic anhydride Anti-diabetic efficacy

New insights into nitric oxide biosynthesis underpin lateral root development

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Molecular Plant 2024年第5期17卷 691-693页

作者： Kapuganti Jagadis Gupta Nidhi yadav Aprajita Kumari Gary J.Loake National Institute for Plant Genome Research Aruna Asaf Ali MargNew Delhi 110070India Institute of Molecular Plant sciences School of Biological SciencesUniversity of EdinburghEH93BF EdinburghUK Centre for Engineering Biology School of Biological SciencesUniversity of EdinburghEH93BF EdinburghUK

In recent years,nitric oxide(NO)has emerged as a key redox signaling molecule in plants functioning in the regulation of key developmental programs and the orchestration of responses to a plethora of environmental cues(Kolbert et al.,2019).The predominant route for the transfer of NO bioactivity is through s-nitrosylation,the addition of an NO moiety to a protein cysteine thiol to form an s-nitrosothiol(Yun et al.,2011).specificity for this process is established by the structural constraints imposed by tertiary protein structure in gating access to given cysteine redox switches and associated proteins that can either facilitate the addition or removal of the NO moiety at these residues(Umbreen et al.,2018).

关键词： moiety addition redox

Layer chicken microbiota:a comprehensive analysis of spatial and temporal dynamics across all major gut sections

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Journal of Animal science and Biotechnology 2024年第3期15卷 1056-1070页

作者： yadav sharma Bajagai Thi Thu Hao Van Nitish Joat Kapil Chousalkar Robert J.Moore Dragana stanley Institute for Future Farming systems Central Queensland UniversityRockhamptonQLD 4701Australia school of science RMIT UniversityBundooraVIC 3083Australia school of Animal and Veterinary sciences The University of AdelaideRoseworthySouth Australia 5371Australia

Background The gut microbiota influences chicken health,welfare,and productivity.A diverse and balanced microbiota has been associated with improved growth,efficient feed utilisation,a well-developed immune system,disease resistance,and stress tolerance in *** studies on chicken gut microbiota have predominantly focused on broiler chickens and have usually been limited to one or two sections of the digestive system,under con-trolled research environments,and often sampled at a single time *** extend these studies,this investigation examined the microbiota of commercially raised layer chickens across all major gut sections of the digestive system and with regular sampling from rearing to the end of production at 80 *** aim was to build a detailed picture of microbiota development across the entire digestive system of layer chickens and study spatial and temporal *** The taxonomic composition of gut microbiota differed significantly between birds in the rearing and pro-duction stages,indicating a shift after laying *** microbiota compositions were observed between proven-triculus and gizzard,as well as between jejunum and ileum,likely due to their anatomical ***-lus dominated the upper gut in pullets and the lower gut in older *** oesophagus had a high proportion of Proteobacteria,including opportunistic pathogens such as *** abundance of Gallibacterium increased after peak production in multiple gut *** was enriched in the late-lay phase compared to younger birds in multiple gut *** influenced microbial richness and diversity in different *** upper gut showed decreased diversity over time,possibly influenced by dietary changes,while the lower gut,specifi-cally cecum and colon,displayed increased richness as birds ***,age-related changes were inconsist-ent across all organs,suggesting the influence of organ-specific factors in micro

关键词： Chicken microbiota Gut microbiota Layers spatial variation Temporal variation