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Philippine retinoblastoma initiative multi-eye center study 2010-2020

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International Journal of Ophthalmology(English edition) 2024年第1期17卷 144-156页

作者： Roland Joseph d.Tan Gary John V.mercado Patricia E.Cabrera Paulita Pamela P.Astudillo Rolando Enrique d.domingo Josept mari s.Poblete Charmaine Grace m.Cabebe Adriel Vincent R.Te melissa Anne s.Gonzales Jocelyn G.sy Beltran Alexis A.Aclan Jayson T.so Fatima G.Regala Kimberley Amanda K.Comia Josemaria m.Castro mara Augustine s.Galang Aldous dominic C.Cabanlas Benedicto Juan E.Aguilar Gabrielle s.Evangelista Jo michael maniwan Andrei P.martin Calvin Y.martinez John Alfred H.Lim Rena Ivy Bascuna Rachel m.Ng Kevin B.Agsaoay Kris Zanna A.Acluba-Arao Ellaine Rose V.Apostol Beatriz m.Prieto department of Ophthalmology and Visual sciences Philippine General HospitalManila 1000Philippines department of Ophthalmology Baguio General Hospital and Medical CenterBaguio City 2600Philippines department of Ophthalmology Manila Doctors HospitalManila 1000Philippines department of Ophthalmology Rizal Medical CenterPasig City 1600Philippines department of Ophthalmology Jose B.Lingad Memorial Regional HospitalPampanga 2000Philippines department of Ophthalmology Southern Philippines Medical CenterDavao City 8000Philippines department of Ophthalmology East Avenue Medical CenterQuezon City 1100Philippines department of Ophthalmology Northern Mindanao Medical CenterCagayan de Oro City 9000Philippines department of Ophthalmology Cebu Velez General HospitalCebu City 6000Philippines Legazpi Eye Center Legazpi City 4500Philippines department of Ophthalmology Cagayan Valley Medical CenterTuguegarao City 3500Philippines

AIm:To provide a comprehensive and more representative national data on the disease,especially on treatment options and outcomes,and to determine access of retinoblastoma patients from Luzon,Visayas and mindanao to eye care,and determine if access is associated with delay in consultation,staging and ***:Cohort study of retinoblastoma patients seen in eleven institutions located in the three major areas of the Philippines namely Luzon,Vizayas and mindanao from ***:Totally 636 patients,involving 821 eyes,were ***(57%)were from Luzon and were seen in institutions in Luzon(72%).Annually,58±10 new cases were seen with 71%having unilateral *** delay of consultation remained long at 9(3,17)mo,longest in patients with unilateral disease(Pd those from the Visayas(Psed on the International Retinoblastoma staging system,only 35%of patients had stage 1 while 47%already had extraocular *** was the most common treatment received by 484 patients while intravenous chemotherapy was received by *** were 250(39%)patients alive,195(31%)dead,85(13%)abandoned,17(3%)refused and 89(14%)with no ***:This study presents the largest cohort of retinoblastoma patients in the Philippines in terms of patients’and participating institutions’number and geographical location and type of institution(private and public).It also presents more comprehensive data on the treatments used and outcomes(survival,globe salvage,and vision retention rates).delay in consultation was still long among patients leading to advanced disease stage and lower survival *** increasing capacity to diagnose and manage retinoblastoma in the country,the delay of consultation remains long primarily due to accessibility issues to eye care institutions especially in the Visayas and financial *** delay was still significant that overall survival rate remain low.

关键词： retinoblastoma Philippines clinical profile

自主机器人使能技术在制造业中的应用（英文）

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Transactions of Nanjing University of Aeronautics and Astronautics 2024年第4期 403-431页

作者： ERd?s Gábor ABAI Kristóf BEREGI Richárd CsEmPEsZ János CsERTEG Tamás GOdó Gábor HAJós mátyás HáY Borbála HORVáTH dániel HORVáTH Gergely JUNIKI ádám KEméNY Zsolt KOVáCs András NACsA János PANITI Imre PEdONE Gianfranco TAKáCs Emma TIPARY Bence ZAHORáN László VáNCZA József 匈牙利研究网络计算机科学与控制研究所布达佩斯经济与技术大学制造科学与技术系 EPIC非盈利创新实验室厄特沃什·罗兰大学

自主制造系统的研究既受益于信息物理融合系统这一新技术的推动，也响应工业实际需求的号召。目前，先进的传感器技术、数字孪生、人工智能和新型通信技术可以支持半结构化工业环境中的自主操作，可实现对生产过程的实时监控、情况识别... 详细信息

自主制造系统的研究既受益于信息物理融合系统这一新技术的推动，也响应工业实际需求的号召。目前，先进的传感器技术、数字孪生、人工智能和新型通信技术可以支持半结构化工业环境中的自主操作，可实现对生产过程的实时监控、情况识别和预测、自动和自适应（重新）规划、团队合作，以及通过学习提高性能。本文总结了实现自主工业机器人技术的主要需求，提出了实现此类系统的通用工作流程，并介绍了HUN-REN sZTAKI最近在装配、焊接、打磨、拾取和放置以及机械加工等多个应用领域的广泛实践。这些解决方案的共同点是以通用的数字孪生概念为核心。最后，本文提出实现工业自主机器人解决方案的一般建议，并讨论了未来要研究的一些开放性问题。

关键词：工业机器人自动化数字孪生使能技术

Advancing towards accurate phenotyping based on metabolic and fibrosis risk in metabolic-dysfunction associated steatotic liver disease:one step closer to personalized care

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Hepatobiliary surgery and Nutrition 2024年第1期13卷 128-131页

作者： sergio muñoz-martínez Alba Jiménez-masip Juan m.Pericàs Liver Unit Vall d’Hebron Hospital UniversitariVall d’Hebron Institut de Recerca(VHIR)Vall d’Hebron Barcelona Hospital CampusBarcelonaSpain Universitat de Barcelona BarcelonaSpain Universitat Autònoma de Barcelona BellaterraBarcelonaSpain Centros de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas(CIBERehd)MadridSpain

Relevance of liver fibrosis amongst diabetic patients with metabolic-dysfunction associated steatotic liver disease(mAsLd)and knowledge gaps Insulin resistance is paramount in the crosstalk between intrahepatic and extrahepatic pathophysiological mechanisms leading to mAsLd(1),hence gaining special relevance in patients diagnosed with type 2 diabetes(T2d).mAsLd is the term that was recently endorsed by an international multidisciplinary consensus panel to replace non-alcoholic fatty liver disease[as non-alcoholic steatohepatitis(NAsH)was replaced by metabolic dysfunction-associated steatohepatitis(mAsH)](2).

关键词： metabolic-dysfunction associated steatotic liver disease(mAsLd) advanced fibrosis type 2 diabetes(T2d) non-invasive tests(NITs)

BaTiO_(3)solid solutions co-doped with Gd^(3+)and Eu^(3+):synthesis,structural evolution and dielectric properties

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Journal of Rare Earths 2024年第10期42卷 1920-1926页

作者： R.martínez-López m.Pérez-labra J.A.Romero-serrano F.R.Barrientos-Hernández m.Reyes-Pérez m.I.Valenzuela-Carrillo G.Urbano-Reyes V.E.Reyes-Cruz G.I.dávila-Pulido Academic Area of Earth sciences and materials Autonomous University of Hidalgo StateRoad Pachuca-Tulancingo Km 4.5 Mineral de La Reforma.Hidalgo42184Mexico metallurgy and materials department ESIQIE-IPNUPALMZacatencoCiudad de Mexico07738Mexico Autonomous University of Coahuila Boulevard Adolfo López Mateos S/nNueva RositaCoahuila26800Mexico

In this paper,the synthesis,structural evolution,and dielectric properties of BaTiO_(3)solid solutions codoped with rare earth elements(Gd^(3+)and Eu^(3+))prepared using the solid-state reaction method are *** pure precursor powders of BaCl_3,TiO_(2),Gd_(2)O_(3),and Eu_(2)O_(3)were mixed in stoichiometric proportions,ground in an agate mortar before being uniaxially pressed at 250 mPa and sintered at 1300℃in air atmosphere for 6 h to obtain Ba_(1-3x)Gd_(2x)Ti_(1-3x)Eu_(4x)O_(3)(x=0,0.0015,0.01 and0.1).X-ray diffraction(XRd)and Rietveld's refinement results reveal the crystal phase ferroelectric tetragonal BaTiO_(3)for the samples with x=0,0.0015 and 0.01,as well as a consistent increment in the lattice parameters caused by the *** solubility limit of Gd^(3+)and Eu^(3+)in the BaTiO_(3)structure is reached for the sample with x>0.01,and the orthorhombic Eu_2TiO_(5)and monoclinic BaTi_(2)O_(5)secondary phases were *** Raman results show the characteristic peaks of ferroelectric tetragonal BaTiO_(3)around 716 cm^(-1)(LO of A1 symmetry),515 cm^(-1)(TO of A1 symmetry),and 305 cm^(-1)(B1).The maximum relative permittivity measured at 1 kHz was recorded to be 6151.8 for the sample with x=0.0015,and a decrease in the Curie temperature to 105℃with respect to the undoped sample was *** punctual microanalysis for the samples with x=0.0015,0.01,and 0.1 reveals grains composed of Ba,Ti,O,Gd,and Eu homogeneously distributed in the BaTiO_(3)*** Ba/Ti ratios for samples with x=0.0015,0.01 and 0.1 are 2.86,2.91,and 0.68,respectively,indicating substitution at the Ti site for samples with x=0.0015 and 0.01 and a substitution at the Ba site for the sample with x=0.1.

关键词： BaTiO_(3) doping Gadolinium Europium synthesis Rare earths

Impact of sex on the outcomes of deceased donor liver transplantation

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World Journal of Transplantation 2024年第1期14卷 120-129页

作者： Oya m Andacoglu Isabel s dennahy Nicole C mountz Luisa Wilschrey Arzu Oezcelik division of Transplantation and Advanced Hepatobiliary surgery University of UtahSalt Lake CityUT 84112United States department of surgery University of EssenEssen D-45122Germany department of surgery The University of Oklahoma Health Sciences CenterOklahoma CityOK 73117United States department of surgery University of Oklahoma College of MedicineOklahoma CityOK 73117United States

BACKGROUNd data examining the impact of sex on liver transplant(LT)outcomes are *** is clear that further research into sex-related differences in transplant patients is necessary to identify areas for *** of these differences may help to identify specific areas of focus to improve on the organ matching process,as well as the peri-and post-operative care of these *** To utilize data from a high-volume Eurotransplant center to compare characteristics of male and female patients undergoing liver transplant and assess association between sex-specific variables with short-and long-term post-transplant *** A retrospective review of the University of Essen’s transplant database was performed with collection of baseline patient characteristics,transplant-related data,and short-term *** of these data were made with shapiro-Wilk,mann-Whitney U,χ2 and Bonferroni tests applied where appropriate.A P value ofs accepted as statistically *** Of the total 779 LT recipients,261(33.5%)were *** patients suffered higher incidences of acute liver failure and lower incidences of alcohol-related or viremic liver disease(P=0.001).Female patients were more likely to have received an organ from a female donor with a higher donor risk index score,and as a high urgency offer(all Pseline characteristics of male and female recipients were also significantly *** multivariate hazard regression analysis,recipient lab-model for End-stage Liver disease score and donor cause of death were associated with long-term outcomes in ***-operative diagnosis of hepatocellular carcinoma,age at time of listing,duration of surgery,and units transfused during surgery,were associated with long-term outcomes in *** of complications was associated with long-term outcomes in both *** survival was similar in both males and females;however,when stratified by age,females<50 y

关键词： Liver transplant Outcomes survival Peri-and post-operative care

synthesis and applications of lanthanoid complexes of pentadentate and hexadentate N_(5) and N_(6) macrocycles:A review

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Journal of Rare Earths 2024年第1期42卷 1-15,I0001页

作者： Julio Corredoira-Vázquez Cristina González-Barreira Paula Oreiro-martínez Ana m.García-deibe Jesús sanmartín-matalobos matilde Fondo departamento de Química Inorganica Facultade de QuímicaUniversidade de Santiago de CompostelaCampus Vida15782Santiago de CompostelaSpain Phantom-g CICECO-Aveiro Institute of MaterialsDepartment of PhysicsUniversity of Aveiro3810-193AveiroPortugal Institute of materials(imATUs) Universidade de Santiago de Compostela15782Santiago de CompostelaSpain

In this paper,the lanthanoid complexes of N_(5) and N_(6) macrocycle ligands,without pendant arms or additional heteroatoms,are *** review covers the period from 2015 to the current date,since in 2014 schiff base macrocyclic ligands incorporating the pyridine moiety,and their complexes,were revised,and in 2015 the chemistry of pentaaza macrocycle ligands with rare earth metals was also *** and phthalocyanine ligands are not included in this review,which primarily focuses on complexes with schiff bases and amines without pendant arms or any additional donor other than *** synthetic methods,structural characterization,based on single X-ray crystal data,and properties of the lanthanoid complexes,with special attention to magneto-structural correlations,are presented herein.

关键词： lanthanoid N_(5),N_(6)macrocycle Coordination chemistry Chirality Biological activity molecule magnet

Reactions induced by 30 meV 3He beam on 9Be:cluster transfer reactions

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Chinese Physics C 2024年第1期48卷 61-70页

作者： B.A.Urazbekov T.Issatayev s.m.Lukyanov A.Azhibekov A.s.denikin K.mendibayev d.m.Janseitov Yu E.Penionzhkevich K.A.Kuterbekov T.K.Zholdybayev Gumiliyev Eurasian National University 2 Satpayev StrAstanaKazakhstan Institute of Nuclear Physics 1 Ibragimov StrAlmatyKazakhstan Bogolubov laboratory of Theoretical Physics JINR20 Joliot Curie StrDubnaRussia Flerov laboratory of Nuclear Reactions JINR20 Joliot Curie StrDubnaRussia Korkyt-ata state University 29A Aiteke-Byi StrKyzylordaKazakhstan dubna state University 19 Universitetskaya StrDubnaRussia Al-Farabi Kazakh National University AlmatyKazakhstan

An experiment was conducted for studying the cluster structure of Be induced by He ions at an energy of 30 *** results of the nuclear reaction^(3)He+^(9)Be,the differential cross sections for the exit channels–elastic,inelastic,α+^(8)Be,^(6)He+^(6)Be,^(6)Li+^(6)Li,and^(7)Be+^(5)He–were *** and inelastic scattering data were treated within both the optical model and coupled channel method.A new set of optical potentials was considered for the elastic *** deformation parameter was established for the transition 3/2→5/*** transfer reactions were analyzed via the coupled reaction channel *** nuclear reactions with the exit channels^(6)He+^(6)Be,^(6)Li+^(6)Li,and^(7)Be+^(5)He were complemented by two-step transfer *** contribution of each reaction mechanism were shown and compared with the findings of other authors.

关键词： cluster transfer reaction mechanisms coupled equations

magnetic Topological dirac semimetal Transition driven by sOC in Eumg_(2)Bi_(2)

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Chinese Physics Letters 2024年第1期41卷 63-67页

作者：王佳萌钱浩吉姜琦乔山叶茂 state Key laboratory of Functional materials for Informatics Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai 200050China Center of materials science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China Research Center for Intelligent Chips and devices Zhejiang LabHangzhou 311121China Center for Transformative science ShanghaiTech UniversityShanghai 201210China school of Physical science and Technology ShanghaiTech UniversityShanghai 201210China shanghai synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China

magnetic topological semimetals have been at the forefront of condensed matter physics due to their ability to exhibit exotic transport *** the interplay between magnetic and topological orders in systems with broken time-reversal symmetry is crucial for realizing non-trivial quantum *** delve into the electronic structure of the rare-earth-based antiferromagnetic dirac semimetal Eumg_(2)Bi_(2) using first-principles calculations and angle-resolved photoemission *** calculations reveal that the spin-orbit coupling(sOC)in Eumg_(2)Bi_(2) prompts an insulator to topological semimetal transition,with the dirac bands protected by crystal *** linearly dispersive states near the Fermi level,primarily originating from Bi 6p orbitals,are observed on both the(001)and(100)surfaces,confirming that Eumg_(2)Bi_(2) is a three-dimensional topological dirac *** research offers pivotal insights into the interplay between magnetism,sOC and topological phase transitions in spintronics applications.

关键词： spectroscopy topological dirac

Audits of death in HIV-Infected Children and Adolescents Followed up in the Pediatric department of the Regional Teaching Hospital of Borgou/Alibori from 2005 to 2020

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Open Journal of Pediatrics 2024年第2期14卷 285-296页

作者： Alphonse Noudamadjo mohamed Falilatou Agbeille dénagan Kévin Amoussou médétinmè Gérard Kpanidja lahanatou séidou Chantal Chabi Réckya Kilaya Julien didier Adédémy Agossou Joseph mother and Child department Faculty of Medicine University of Parakou Parakou Benin Pediatric department Regional Teaching Hospital of Borgou/Alibori Parakou Benin

Introduction: Human immunodeficiency virus (HIV) is a major public health problem with high morbidity and mortality among children. The objective of this work was to audit the deaths of children and adolescents with HIV infection followed up in the pediatric department of the Regional Teaching Hospital of Borgou/Alibori (CHUdB/A) the from 2005 to 2020. Patients and method: This was a retrospective and descriptive study conducted in the pediatric department of CHUd/B-A in Parakou. All children with HIV infection who died from January 1, 2005 to August 31, 2020 were included. data collection was carried out in three stages: a phase of medical records processing, a phase of community survey and a phase of death audits. The variables studied were sociodemographic, clinical, biological, therapeutic and evolutionary. Results: Over the study period, the data of 464 infected children were recorded, including 92 deaths, representing a case fatality rate of 19.83%. severe acute malnutrition (69.23%), gastro-intestinal tract infections (43.58%) and serious opportunistic pulmonary infections (24.36% pulmonary tuberculosis and 19.23% pneumocystis) were the main causes of death. The main dysfunctions found were: the delayed diagnosis of HIV infection (79.35%), the absence or delay in consultation when the child’s clinical condition deteriorates (32.61% and 47.83%), delayed initiation of antiretroviral treatment (42.39%) and non-adherence to treatment (38.04%). Non-adherence to treatment was predominant in adolescents (90.49%). Conclusion: specific interventions for early detection, adequate nutritional care, psychosocial support for adolescents and mothers of children are necessary to reduce mortality due to HIV among children and adolescents.

关键词： HIV death Children Adolescents dysfunctions Benin