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Endotoxins in the prostatic secretions of chronic prostatitis patients:a need for further biomarkers through the use of proteomics

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Asian Journal of Andrology 2006年第1期8卷 123-124页

作者： sashi s.Kommu stewart Reiss The Royal Marsden NHs Foundation Trust Fulham RoadLondon SW3 6JJUK Brighton and sussex Medical school University of SussexBrighton BN1 9PXUK

Dear sir,Dai et al.[1] must be commended on their useful investigation of the clinical significance of endotoxins in the expressed prostatic secretions （EPs） of chronic prostatitis （CP） patients. However, we take issue with their conclusion. The conclusion that EPs endotoxin determination is helpful in diagnostic confirmation is plausible,

关键词： Proteomics Bacterial Infections Biological Markers Chronic Disease Endotoxins Humans Male Prostate Prostatitis

Bulk heterojunction thin film formation by single and dual feed ultrasonic spray method for application in organic solar cells

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Journal of semiconductors 2016年第9期37卷 47-50页

作者： D.M.Marathe H.s.Tarkas M.s.Mahajan G.s.Lonkar s.R.Tak J.V.sali Organic Photovoltaic Laboratory North Maharashtra UniversityJalgaon(MS)425001India

We here present a way of preparing the polymer： fullerene BHJ using dual feed method which can lead to formation of pure phases. In this report, we present results of our initial experiments in this *** effect of process parameters on the thickness and surface roughness of the active layer has been *** structural and optical properties have been studied using the optical microscope, UV–visible spectroscopy and photoluminescence spectroscopy. significant PL quenching indicates efficient charge separation in the BHJ formed using this technique. We have also compared the BHJ thin films prepared with this dual feed ultrasonic technique with the single feed spray method. The BHJ formed using this technique has been used as an active layer in OsC.

关键词： P3HT PCBM dual feed ultrasonic spray method organic solar cell

Influence of carbon nano tubes on mechanical, metallurgical and tribological behavior of magnesium nanocomposites

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Journal of Magnesium and Alloys 2017年第3期5卷 326-335页

作者： s.T.selvamani s.Premkumar M.Vigneshwar P.Hariprasath K.Palanikumar Department of Mechanical Engineering Vel Tech Multi Tech Engineering CollegeChennai 600062TamilnaduIndia Department of Mechanical Engineering Vel Tech Dr.RR Dr.SR UniversityChennai 600062TamilnaduIndia Department of Manufacturing Engineering Annamalai UniversityChidambaram 608002TamilnaduIndia Department of Mechanical Engineering Sai Ram Institute of TechnologyChennai 600044TamilnaduIndia

In this research work,three different reinforcements of Carbon Nano Tubes(in weight%)such as 2%,3%and 4%were added to the magnesium AZ91D grade magnesium alloy to fabricate the Nanocomposites through stir casting *** effects of volume percentage on the mechanical,metallurgical and wear behavior were *** composites with 4%reinforcement show high hardness while the composites with 3%reinforcement show better tensile and yield strength and also an improved wear resistance compared to ***,the characterization of the Nanocomposites were made using Optical Microscopy,scanning Electron Microscopy,Finite Element-scanning Electron Microscopy and Transmission Electron Microscopy to understand its nature.

关键词： CNT Magnesium alloy stir casting Wear behavior

EUs for pancreatic cystic neoplasms: The roadmap to the future is much more than just a few shades of gray

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Asian Pacific Journal of Tropical Medicine 2016年第12期9卷 1193-1196页

作者： Tejas Kirtane Manoop s.Bhutani Department of Gastroenterology Hepatology and NutritionUniversity of Texas MD Anderson Cancer Center

Pancreatic cystic and neoplasms are being diagnosed with increasing frequency. Accurate diagnosis and determination of benign versus malignant lesions is crucial for determining need for surveillance versus surgery or endoscopic therapy as well as avoiding unnecessary surgery in cysts with no malignant potential. Tumor markers such as KRAs and GNAs hold promise, but which molecular marker or a combination of markers is most useful and cost effective remains to be seen. Advanced imaging with confocal laser endomicroscopy can serve as an optical biopsy and play a part in the diagnostic algorithm. Microforceps aided biopsy of pancreatic cyst wall and tumor contents hold great promise as they allow direct tissue acquisition. Much progress has been made in the role of EUs guided evaluation of pancreatic cystic neoplasms over the last several years, and with the advances enumerated above, the future is more than just a few shades of grey. Future studies should include prospective multiarm trials of microforceps biopsy versus conventional EUs-FNA and use of biochemical and molecular markers, confocal laser endomicroscopy or a combination thereof to determine best approach to pancreatic cystic neoplasms. In Osler's words, ‘Medicine is a science of uncertainty and an art of probability'. Incorporation of advanced imaging and molecular markers into a new diagnostic algorithm with subsequent validation through retrospective and prospective studies has the potential to increase diagnostic accuracy and guide optimal management of patients and improve outcomes.

关键词： EUs-FNA Endoscopic ultrasound Pancreatic cystic neoplasms Radiofrequency ablation nCLE Molecular markers

Local recurrence of a parosteal osteosarcoma 21 years after incomplete resection

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Chinese Journal of Cancer 2011年第12期30卷 861-866页

作者： Andrés Combalia Ernesto Muoz-Mahamud Antonio Palacín Jaume Pomés Vicente López Department of Orthopaedic surgery and Traumatology Orthopaedic Oncology Unit Hospital Clinic Faculty of Medicine University of Barcelona Barcelona 08036 Spain Department of Pathology Hospital Clinic Faculty of Medicine University of Barcelona Barcelona 08036 Spain Department of Radiology Hospital Clinic Faculty of Medicine University of Barcelona Barcelona 08036Spain

Parosteal osteosarcoma (POs) is the most common form of surface osteosarcoma. Its symptoms are insidious and its duration prior to diagnosis is considerably longer than that of other types of osteosarcoma. We report a case of POs with a growing mass but no evidence of metastasis. This tumor, which was diagnosed as calcified hematoma with benign characteristics, was incompletely resected in our hospital 21 years before the diagnosis of recurrence. The patient underwent a wide en bloc resection in our hospital and was free of symptoms, with no signs of tumor recurrence or metastasis during a 53-month follow-up.

关键词：骨肉瘤复发持续时间 POs 不完全诊断症状肿瘤

The second pluri-genus of smoothable Gorenstein surface singularities

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science China Mathematics 2010年第3期53卷 635-639页

作者： YAU stephen s. T. Department of Mathematics Statistics and Computer Science University of Illinois at Chicago

For complete intersection isolated surface singularities, Okuma gave a formula for the second plurigenus relating geometry genus, Milnor number and Tjurina number. We generalize Okuma’s theorem to Gorenstein smoothab... 详细信息

关键词： second pluri-genus smoothable Gorenstein Milnor number Tjurina number

Magnetotelluric sounding in western Tibet

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Chinese science Bulletin 1997年第8期42卷 678-681页

作者： Ma, XB Kong, XR Yu, s Institute of Geophysics Chinese Academy of Sciences Beijing China

THE magnetotelluric sounding(MT)profile from Gyirong to sangehu in western Tibet indi-cates that the surveyed region is divided into four tectonic units by Yarlung Zangbo sutureZone(s.Z.),Bangongco-Nujiang *** Lugu **... 详细信息

关键词： magnetotelluric sounding conductivity structure of lithosphere high conductivity layer Tibet Gandise unit Qiangtang unit.

腹侧海马CA1区HCN2通道功能下调参与慢性炎症痛

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中国疼痛医学杂志 2024年第1期30卷 51-51页

作者：刘风雨(译) 北京大学神经科学研究所

海马作为边缘系统的重要结构,在疼痛感知和疼痛慢性化中起关键作用。近期对人类和啮齿类的研究表明,腹侧海马CA1 (ventral hippocampal CA1,vCA1)的功能失调,包括神经元兴奋性降低以及与其他脑区功能连接度降低,参与调控疼痛慢性化。然... 详细信息

海马作为边缘系统的重要结构,在疼痛感知和疼痛慢性化中起关键作用。近期对人类和啮齿类的研究表明,腹侧海马CA1 (ventral hippocampal CA1,vCA1)的功能失调,包括神经元兴奋性降低以及与其他脑区功能连接度降低,参与调控疼痛慢性化。然而,vCA1调控疼痛的分子机制不清。超极化激活环核苷酸门控阳离子通道(hyperpolarization-activated cyclic nucleotide-gated channels,HCN),尤其是HCN1和HCN2亚型,在CA1区锥体神经元表达丰富,具有稳定膜电位等作用。该研究采用完全弗氏佐剂(complete Freund’s adjuvant,CFA)小鼠模型,探讨vCA1区HCN通道是否参与调节慢性炎症痛。

关键词：超极化激活环核苷酸门控阳离子通道神经元兴奋性腹侧海马慢性化完全弗氏佐剂边缘系统 CA1区功能失调

深入推进党风廉政建设和反腐败工作不断取得全面从严治党新成效 001

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