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Increased prevalence of intestinal inflammation in patients with liver cirrhosis

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World Journal of Gastroenterology 1999年第5期5卷 391-396页

作者： saitoh O sugi K Lojima K Matsumoto H Nakagawa K Kayazawa M Tanaka s Teranishi T Hirata I Katsu Ki K second Department of Internal Medicine Osaka Medical College Takatsuki Japan Department of Gastroenterology Ijinkai Takeda General Hospital Kyoto Japan

AIM To investigate the pathophysiology of the digestive tract in patients with liver *** In 42 cirrhotic patients and 20control subjects, the following fecal proteinswere measured by enzyme-linkedimmunosorb6nt assay: albumin (Alb ),transferrin (Tf), and al-antitrypsin (a,-AT) as amarker for intestinal protein l0ss, hemoglobin(Hb) for bleeding, PMN-eIastase for intestinalinflammation, and secretory lgA for *** The fecaI concentrations of Hb, Alb,Tf, al-AT, and PMN’eIastase were increased in13 (3l%), 8(19%), l0(24%), 6(14%), and 1l(26%) cases among 42 patients, resPectiveIy.F6cal concentration of secretory IgA wasdecreased in 7 (l7%) of 42 patients. However,these fecal concentrations were not related tothe severity or etiology of liver cirrhosis. Theserum Alb level was significantIy decreased inpatients with intestinal protein Ioss c0mpared tothat in patients without intestinal protein *** These findings suggest that: rob6sides the weIl’known pathological conditions,such as bleeding and protein loss, intestinaIinflammati0n and decreased intestinaI immunityare found in cirrhotic patients, @ intestinalprotein loss contributes to hypoalbuminemia incirrhotic patients, and @ intestinaI inflammationshouId not b6 0verlooked in cirrhotic patients,since it may contribute to or cause intestinalprotein Ioss and oth6r various pathologicalconditions.

关键词： liver cirrhosis intestinal inflammation secretory IgA fecal proteins

Geometric-phase-induced arbitrary polarization and orbital angular momentum generation in helically twisted birefringent photonic crystal fiber

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Photonics Research 2020年第8期8卷 1278-1288页

作者： TAKEsHI FUJIsAWA KUNIMAsA saitoh Graduate school of Information science and Technology Hokkaido UniversityJapan

The evolutions of polarization and orbital angular momentum(OAM)states of light in helically twisted birefringent photonic crystal fibers(TB-PCFs)are *** is shown that a circular polarization(CP)component(s3 of a stokes parameter)is periodically excited when usual linearly polarized(LP)modes of PCF are *** excitation originates from a geometric phase in *** s3 excitation is larger for larger linear birefringence for a fixed twisting *** the linear birefringence is large enough,a CP filtering behavior can be seen in addition to the s3 *** the analytical consideration of the sign of the geometric phase,the TB-PCF with periodical inversion of twisting is proposed to generate arbitrary polarization state on the Poincaré***,an OAM state generation in multimode TB-PCFs is shown for higher-order LP mode *** observing a far-field interference pattern from TB-PCF mixed with LP01 mode,a vortex associated with the OAM state can be *** to the single-mode case,by using periodical twisting inversion,efficient OAM generation is *** results indicate that by simply launching fiber’s LP mode into TB-PCF,arbitrary polarization and OAM states can be generated,leading to a novel mechanism for the manipulation of the spatial state of light.

关键词： polarization fiber momentum

Evolutionary relationships of mitogenomes in a recently radiated Old World avian family

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Avian Research 2023年第2期14卷 153-159页

作者： Wenqing Zang Zhiyong Jiang Per G.P.Ericson Gang song sergei VDrovetski Takema saitoh Fumin Lei Yanhua Qu Key Laboratory of Zoological systematics and Evolution Institute of ZoologyChinese Academy of SciencesBeijingChina College of Life sciences University of Chinese Academy of SciencesBeijingChina Department of Bioinformatics and Genetics Swedish Museum of Natural HistoryPO Box 50007SE-10405StockholmSweden Laboratories of Analytical Biology National Museum of Natural HistorySmithsonian InstitutionWashingtonDC 20004USA U.s.Geological survey Eastern Ecological Science Center at Patuxent Research RefugeLaurelMD 20708USA Yamashina Institute for Ornithology AbikoChibaJapan Center for Excellence in Animal Evolution and Genetics Chinese Academy of SciencesKunming650223China

Environmentally heterogeneous mountains provide opportunities for rapid diversification and *** family Prunellidae(accentors)is a group of birds comprising primarily mountain specialists that have recently radiated across the Palearctic *** rapid diversification poses challenges to resolving their *** we sequenced the complete mitogenomes and estimated the phylogeny using all 12(including 28 individuals)currently recognized species of *** reconstructed the mitochondrial genome phylogeny using 13 protein-coding genes of 12 species and 2 Eurasian Tree sparrows(Passer montanus).Phylogenetic relationships were estimated using a suite of analyses:maximum likelihood,maximum parsimony and the coalescent-based *** times were estimated by implementing a Bayesian relaxed clock model in *** on the BEAsT time-calibrated tree,we implemented an ancestral area reconstruction using RAsP *** phylogenies based on the maximum likelihood,maximum parsimony and sVDquartets approaches support a clade of large-sized accentors(subgenus Laiscopus)to be sister to all other accentors with small size(subgenus Prunella).In addition,the trees also support the sister relationship of *** and ***+*** with 100%bootstrap support,but the relationships among the remaining eight species in the Prunella clade are poorly *** species cluster in different positions in the three phylogenetic trees and the nodes are often poorly *** five nodes separating the seven species diverged simultaneously within less than half million years(i.e.,between 2.71 and 3.15 million years ago),suggesting that the recent radiation is likely responsible for rampant incomplete lineage sorting and gene tree *** area reconstruction indicates a central Palearctic region origin for *** study highlights that whole mitochondrial genome phylogeny can resolve major lineages within Prun

关键词： Incomplete lineage sorting Mitochondrial genome Mountain specialists Radiation

Matrices and Division by Zero z/0 = 0

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Advances in Linear Algebra & Matrix Theory 2016年第2期6卷 51-58页

作者： Tsutomu Matsuura saburou saitoh Division of Mechanical science and Technology Gunma University Kiryu Japan Institute of Reproducing Kernels Kiryu Japan

In this paper, a new viewpoint of the division by zero z/0 = 0 in matrices is introduced and the results will show that the division by zero is our elementary and fundamental mathematics. New and practical meanings for many mathematical and physical formulas for the denominator zero cases may be given. Furthermore, a new space idea for the point at infinity for the Eucleadian plane is also introduced.

关键词： Division by Zero z/0 = 0 Field Y-Field Point at Infinity Infinity Matrix Cramer’s Law Area Volume Parallel Lines Degeneracy of Figures Hooke’s Law

Particle Modeling Based on Interatomic Potential and Crystal structure: A Multi-scale simulation of Elastic-Plastic Deformation of Metallic Material

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World Journal of Nano science and Engineering 2021年第3期11卷 45-68页

作者： Ken-Ichi saitoh Naoya Hanashiro Department of Mechanical Engineering Faculty of Engineering Science Kansai University Suita Japan

We formulate a macroscopic particle modeling analysis of metallic materials (aluminum and copper, etc.) based on theoretical energy and atomic geometries derivable from their interatomic potential. In fact, particles in this framework are presenting a large mass composed of huge collection of atoms and are interacting with each other. We can start from cohesive energy of metallic atoms and basic crystalline unit (e.g. face-centered cubic). Then, we can reach to interparticle (macroscopic) potential function which is presented by the analytical equation with terms of exponent of inter-particle distance, like a Lennard-Jones potential usually used in molecular dynamics simulation. Equation of motion for these macroscopic particles has dissipative term and fluctuation term, as well as the conservative term above, in order to express finite temperature condition. First, we determine the parameters needed in macroscopic potential function and check the reproduction of mechanical behavior in elastic regime. By using the present framework, we are able to carry out uniaxial loading simulation of aluminum rod. The method can also reproduce Young’s modulus and Poisson’s ratio as elastic behavior, though the result shows the dependency on division number of particles. Then, we proceed to try to include plasticity in this multi-scale framework. As a result, a realistic curve of stress-strain relation can be obtained for tensile and compressive loading and this new and simple framework of materials modeling has been confirmed to have certain effectiveness to be used in materials simulations. We also assess the effect of the order of loadings in opposite directions including yield and plastic states and find that an irreversible behavior depends on different response of the particle system between tensile and compressive loadings.

关键词： Molecular Dynamics Particle Method Elasticity Plasticity Nanostructure Multi-scale Modeling

Renal amyloidosis as a late complication of Crohn's disease:a case report and review of the literature from Japan

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World Journal of Gastroenterology 2000年第3期6卷 461-464页

作者： Osamu saitoh Keishi Kojima Tsutomu Teranishi Ken Nakagawa Masanobu Kayazawa Masashi Nanri Yutaro Egashira Ichiro Hirata Ken-ichi Katsu second Department of Internal Medicine Osaka Medical CollegeTakatsukiJapan First Department of Pathology Osaka Medical CollegeTakatsukiJapan

INTRODUCTION secondary amyloidosis is a rare but seriouscomplication of Crohn’s disease(CD).Theincidence of the association of secondaryamyloidosis in patients with CD has been reportedto be 0.5%-8% in Western ***,in Japan,the number of patients with CDcomplicated by amyloidosis is *** of their clinical manifestations andthe incidence of association are ***,we report herein a patient with

关键词： Crohn’s disease/complication renal amyloidosis amyloid deposits

A VAsUALIZATION FOR THE DYNAMIC BEHAVIORs OF THE MIXTURE OF WATER MAss FOR NORTHWEsTERN PACIFIC NEAR JAPAN

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International Journal of Modeling, simulation, and scientific Computing 2013年第S1期4卷 86-103页

作者： KUN ZHAO sATOsHI NAKADA NAOHIsA sAKAMOTO KOJI KOYAMADA CHANDRAJIT BAJAJ YOICHI IsHIKAWA TOsHIYUKI AWAJI TEIJI IN sEI-ICHI saitoh Graduate school of Engineering Kyoto University KyotoKyoto Prefecture606-8501Japan Institute for the Promotion of Excellence in Higher Education Kyoto University KyotoKyoto Prefecture606-8501Japan Department of Computer science The Institute for Computational Engineering and sciences University of Texas at Austin AustinTexas78712USA Department of Geophysics Division of Earth and Planetary sciences Kyoto University KyotoKyoto Prefecture606-8501Japan Data Research Center for Marine-Earth sciences Japan Agency for Marine-Earth science and Technology Yokosuka Kanakawa Prefecture237-0061Japan Japan Marine science Foundation Tokyo Tokyo Metropolis110-0008Japan Laboratory of Marine Bioresource and Environment sensing Faculty of Fisheries sciences Hokkaido University SapporoHokkaido Prefecture060-0808Japan

Recent studies are focusing on the distribution of water mass because the mixture region of water mass is highly related to the rich fishing grounds[Yasuda I.,Watanabe Y.,***.3(3):172–181,1994].Due to the large data size and time-varying property,efficient exploration and visualization of the ocean data is always extremely *** extract the dynamic behaviors of the water mass and its mixture from a large-scale simulated ocean dataset,we developed an efficient visualization system by applying our volume compression method and our volume rendering *** system allows us to investigate the time-varying distributions of ocean physical properties,additionally from the user’s perspective and *** the experiments,we show the generality and expressiveness by applying our system for single-and multi-property visualizations to find some significant ocean water ***,we could obtain a clear visualization result to show the dynamic behaviors of the mixture of water mass for simulation data regarding a location in the northwestern Pacific near Japan.

关键词： Oceanography water mass visualization.

Molecular Dynamics study on Mechanical Properties in the structure of self-Assembled Quantum Dot

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World Journal of Nano science and Engineering 2012年第4期2卷 189-195页

作者： Tatsuya Yamaguchi Ken-ichi saitoh Department of Mechanical Engineering Faculty of Engineering Science Kansai University Suita Japan system Design Major Graduate School of Science and Engineering Kansai University Suita Japan

stress and strain in the structure of self-assembled quantum dots constructed in the Ge/si(001) system is calculated by using molecular dynamics simulation. Pyramidal hut cluster composed of Ge crystal with {105} facets surfaces observed in the early growth stage are computationally modeled. We calculate atomic stress and strain in relaxed pyramidal structure. Atomic stress for triplet of atoms is approximately defined as an average value of pairwise (virial) quantity inside triplet, which is the product of vectors between each two atoms. Atomic strain by means of atomic strain measure (AsM) which is formulated on the Green’s definition of continuum strain. We find the stress (strain) relaxation in pyramidal structure and stress (strain) concentration in the edge of pyramidal structure. We discuss size dependency of stress and strain distribution in pyramidal structure. The relationship between hydrostatic stress and atomic volumetric strain is basically linear for all models, but for the surface of pyramidal structure and Ge-si interface. This means that there is a reasonable correlation between atomic stress proposed in the present study and atomic strain measure, AsM.

关键词： Molecular Dynamics self-Assembled Quantum Dot Germanium silicon Mechanical Property

stress Engineering in (100) and (110) nMOsFETs

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Stress Engineering in (100) and (110) nMOSFETs