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Consumption of rice and fish in an electronic waste recycling area contributes significantly to total daily intake of mercury

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Journal of Environmental sciences 2015年第12期27卷 83-86页

作者： Hanyong Peng Michael s.reid X.Chris Le Division of Analytical and Environmental Toxicology Department of Laboratory Medicine and PathologyUniversity of Alberta

Mercury is a global pollutant due to its widespread use,emission,and long-range transport（Blum,2013;Pacyna et al.,2010）.It is considered a priority pollutant due to its neurological toxicity,persistence,and bioaccumulation（Pacyna et al.,2010;sharma et al.,2015）.Mercury pollution can occur when products that contain mercury are improperly disposed of and mercury is released into the air,water,and soil（Zhang and Wong,2007）.An estimated 22%of the annual world usage of mercury is in electrical equipment such as batteries,thermometers,and discharge lamps,and electronic devices such as monitors and

关键词： Mercury Methyl mercury Electronic waste Biomonitoring Dietary intake Human exposure assessment Environmental health

Carbohydrate biomarkers for future disease detection and treatment

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science China Chemistry 2010年第1期53卷 3-20页

作者： reid suazette Department of Chemistry Georgia State University

Carbohydrates are considered as one of the most important classes of biomarkers for cell types,disease states,protein functions,and developmental ***"binders"that can specifically recognize a carbohydrate biomarker can be used for developing novel types of site specific delivery methods and imaging *** this review,we present selected examples of important carbohydrate biomarkers and how they can be targeted for the development of therapeutic and diagnostic *** are arranged based on disease categories including(1) infectious diseases,(2) cancer,(3) inflammation and immune responses,(4) signal transduction,(5) stem cell transformation,(6) embryo development,and(7) cardiovascular diseases,though some issues cross therapeutic boundaries.

关键词： carbohydrates biomarkers imaging agents boronolectins

Generalized Hopfian Property, a Minimal Haken Manifold, and Epimorphisms Between 3-Manifold Groups

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Acta Mathematica sinica,English series 2002年第1期18卷 157-172页

作者： reid Alan W Department of Mathematics. University of Texas Austin. TX 78712. USA

We address the question that if π_1-surjective maps between closed aspherical 3-manifolds have the same rank on π_1 they must be of non-zero degree. The positive answer is proved for seifert manifolds, which is used in constructing the first known example of minimal Haken manifold. Another motivation is to study epimorphisms of 3-manifold groups via maps of non-zero degree between 3- manifolds. Many examples are given.

关键词： Non-zero degree maps Epimorphisms 3-Manifolds

Controlling plant architecture by manipulation of gibberellicacid signalling in petunia

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Horticulture research 2014年第1期1卷 16-21页

作者： Yin-Chih Liang Michael s reid Cai-Zhong Jiang Department of Plant sciences University of California DavisOne Shields AvenueDavisCA 95616USA Crops Pathology&Genetics research Unit USDA-ARSOne Shields AvenueDavisCA 95616USA

since stem elongation is a gibberellic acid(GA)response,GA inhibitors are commonly used to control plant height in the production of potted ornamentals and bedding *** this study,we investigated interfering with GA signaling by using molecular techniques as an alternative *** isolated three putative GID1 genes(PhGID1A,PhGID1B and PhGID1C)encoding GA receptors from ***-induced gene silencing(VIGs)of these genes results in stunted growth,dark-green leaves and *** also isolated the gai mutant gene(gai-1)from *** have generated transgenic petunia plants in which the gai mutant protein is over-expressed under the control of a dexamethasone-inducible *** system permits induction of the dominant Arabidopsis gai mutant gene at a desired stage of plant development in petunia plants by the application of dexamethasone(Dex).The induction of gai in Dex-treated T1 petunia seedlings caused dramatic growth retardation with short internodes.

关键词： pet plant bedding

Control of the carrier-envelope phases of a synchronously pumped femtosecond optical parametric oscillator and its applications

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Chinese science Bulletin 2008年第5期53卷 642-651页

作者： sUN JingHua Barry J s Gale Derryck T reid Ultrafast Optics Group School of Engineering and Physical Sciences Heriot-Watt University Edinburgh EH14 4AS UK Laboratory of Optical Physics Institute of Physics Chinese Academy of Sciences Beijing 100080 China

The intrinsic synchronization, multi-color outputs and related carrier-envelope phases (CEP) among pulses bring advantages to synchronously pumped femtosecond optical parametric oscillators and the pumping sources for broadband frequency comb generation and ultrashort waveform coherent syn-thesis. In this paper, we discuss our latest research results in this field, which cover the following as-pects: the phase relationship and energy conservation law in an OPO and related experimental verifi-cation; control of the pumping Ti:sapphire femtosecond laser's CEP by self-referencing technology, and its repetition-rate locking by piezoelectric transducer (PZT); CEP locking of the pulses from the OPO by beating the non-phase-matched visible outputs against pump supercontinuum to obtain a driving signal for a fast PZT on the OPO end mirror; the generation of a broadband frequency comb spanning from 400 nm to 2.4 μm with 1.2 kHz bandwidth; and the realization of coherent interference between phase controlled pump pulses and signal second harmonic pulses.

关键词：光学参数振荡器载波包络相同步控制超短光脉冲

Gene expression profiles of the southern house mosquito Culex quinquefasciatus during exposure to permethrin

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Insect science 2018年第3期25卷 439-453页

作者： William r. reid Lee Zhang Youhui Gong Ting Li Nannan Liu Department of Entomology and Plant Pathology Auburn University Auburn Alabama USA Genomics and sequencing Laboratory Auburn University Auburn Alabama USA Department of Honeybee Protection and Biosafety Institute of Apicultural Research Chinese Academy of Agricultural Sciences Beijing China

Insecticide resistance is a major obstacle to the management of diseasevectoring mosquitoes worldwide. The genetic changes and detoxification genes involved in insecticide resistance have been extensively studied in populations of insecticide-resistant mosquitoes, however few studies have focused on the resistance genes upregulated upon insecticide exposure and the possible regulation pathways involved in insecticide resis- tance. To characterize the changes in gene expression during insecticide exposure, and to investigate the possible connection of known regulation pathways with insecticide resistance, we conducted rNA-seq analysis of a highly permethrin-resistant strain of Culex quinquefasciatus following pcrmethrin exposure. Gene expression profiles revealed a total of 224 upregulated and 146 downregulated genes when compared to a blank acetone carrier treated control, respectively, suggesting that there were multiple, but specific genes involved in permethrin resistance. Functional enrichment analysis showed that the upregulated genes contained multiple detoxification genes including a glutathione s-transferase and multiple eytochrome P450 genes, as well as several immune-related genes, while the downregulated genes consisted primarily of proteases and carbohydrate metabolism and transport. Further analysis showed that permethrin exposure resulted in a decrease in the expression of serum storage proteins and likely represented a delay in the development of the fourth instar possibly due to a decrease in feeding. This effect was more pronounced in an insecticide-resistant strain than in an insecticide-susceptible strain and may represent a behavioral mechanism of insecticide resistance in Culex mosquitoes.

关键词： cytochrome P450 insecticide resistance proteases

Overexpression of an ABA biosynthesis gene using a stress-inducible promoter enhances drought resistance in petunia

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Horticulture research 2015年第1期2卷 255-263页

作者： Alejandro C Estrada-Melo Chao Ma Michael s reid Cai-Zhong Jiang Department of Plant sciences University of California DavisDavisCAUSA United states Department of Agriculture Crops Pathology and Genetic Research UnitAgricultural Research ServiceDavisCAUSA

The response of plants to drought stress includes reduced transpiration as stomates close in response to increased abscisic acid(ABA)*** overexpression of 9-cis-epoxycarotenoid dioxygenase(NCED),a key enzyme in ABA biosynthesis,increases drought resistance,but causes negative pleiotropic effects on plant growth and *** overexpressed the tomato NCED(LeNCED1)in petunia plants under the control of a stress-inducible promoter,*** water stress,the transgenic plants had increased transcripts of NCED mrNA,elevated leaf ABA concentrations,increased concentrations of proline,and a significant increase in drought *** transgenic plants also displayed the expected decreases in stomatal conductance,transpiration,and *** 14 days without water,the control plants were dead,but the transgenic plants,though wilted,recovered fully when ***-watered transgenic plants grew like non-transformed control plants and there was no effect of the transgene on seed dormancy.

关键词： inducible pet drought

The role of landscape setting in minimizing hydrogeomorphic impacts of flow regulation

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International Journal of sediment research 2013年第2期28卷 149-161页

作者： H.E.reid G.J.BrIErLEY K.MCFArLANE s.E.COLEMAN s.TrOWsDALE school of Environment The University of Auckland Department of Civil and Environmental Engineering The University of Auckland

The Tongariro Power Development scheme（TPDs） is used to regulate flow in the headwaters of the largest catchment on the North Island of New Zealand（the Waikato）.Two small dams,the rangipo Dam and the Poutu Intake Dam,were constructed in 1973 and *** flow regime of the river is managed to divert freshes into the power scheme,but allows flows larger than 100 m;s;to be released,to rework and transport sediment through the catchment. Analysis of aerial photos and maps spanning 1928 to 2007,alongside field measurements,show that there have been few hydrogeomorphic adjustments since dam *** includes limited changes to channel geometry,channel planform and bed material organization immediately downstream of the *** addition,offsite effects are minimal, both 500 m downstream of each dam,and in the more sensitive,less confined reaches in the lower catchment（11 km downstream of the Poutu Intake dam）.The limited changes can be attributed to the locations of the dams within reaches characterised by bedrock gorges and confined within *** locations act to flush sediments and impose margins that allow minimal adjustment of the *** material within this reach is characterised by the presence of a boulder *** is sourced from long-term incision into lahar deposits,and acts to limit the rate of incision, creating a steep and stable base upon which active fractions are *** as importantly,significant storage in the low-relief volcanic plateau located in the upper catchment acts to disconnect and store the high sediment yields generated by active volcanic cones in the western sub-catchment upstream of the *** limits the rate of sediment supply to regulated *** from this study show that analysis of reach-scale controls is essential in framing dam site locations in relation to the distribution of reaches and landscape units across the *** this instance, tributary inputs downstream of the dams do not repl

关键词： Flow regulation Landscape setting Landscape connectivity sediment storage Channel planform

HIF-1 inhibitors as anti-cancer therapy

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science China Chemistry 2011年第1期54卷 24-30页

作者： MOOrING suazette reid Department of Chemistry and Center for Biotechnology and Drug Design Georgia State University

Hypoxia is a hallmark of solid *** increases the progression of malignancy and metastasis by promoting angiogenesis and triggering the over-expression of various protein products critical for tumor *** transcription factor HIF-1 mediates cellular response to hypoxia by promoting processes,such as glycolysis and *** evidence has demonstrated that expression of HIF-1 is strongly associated with poor patient prognosis and activation of HIF-1 contributes to malignant behavior and therapeutic ***,HIF-1 is a viable target for cancer *** review summarizes agents that have been described in the literature as HIF-1 *** majority of these compounds are indirect inhibitors of HIF-1.

关键词： HIF-1 hypoxia cancer therapy