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The microstructure characteristics and fracture behavior of the polyhedral primary iron-rich phase and plate-shaped eutectic iron-rich phase in a high-pressure die-cast Alsi10mnmg alloy

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Journal of materials science & Technology 2023年第9期140卷 201-209页

作者： X.Y.Jiao Y.X.Liu J.Wang W.N.Liu A.X.Wan stuart Wiesner s.m.xiong school of materials science and Engineering Northeastern UniversityShenyang 110819China school of materials science and Engineering Tsinghua UniversityBeijing 100084China Key Laboratory of Lightweight structural materials Liaoning ProvinceNortheastern UniversityShenyang 110819China Key Laboratory for Advanced materials Processing Technology Tsinghua UniversityBeijing 100084China shanghai synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China Ein Unternehmen der ALUmINIUm RHEINFELDEN Group RHEINFELDEN 79618Germany

The characterization of multiple iron-rich phases in high-pressure die-cast Alsi10mnmg alloy was studied.Attention was focused on the formation and fracture behavior of the primary iron-rich phase((P-ImC)_(I))formed in the shot sleeve and plate-shaped eutectic iron-rich phase in high-pressure die cast(HPDC)Alsi10mnmg alloy.Results show that multiple types of iron-rich phases with various morphologies,in-cluding primary iron-rich phases(polyhedral(P-ImC)_(I) and(P-ImC)_(II))and eutectic iron-rich phases(plate-shaped,net shape,and fish-bone shape),were found in HPDC Alsi10mnmg.Coarse(P-ImC)_(I) formed in the shot sleeve were distributed in the interface between primaryα-Al and binary Al-si eutectic.small size(P-ImC)_(II) and various eutectic iron-rich phases formed in the die cavity and they were distributed in Al-si binary eutectic.The primary iron-rich phases belonged to a simple cubic crystal structure with a lattice constant a=1.265 nm and they exhibited a lateral growth characteristic with a termination of{110}surface.βphase was surrounded byδphase and they coexisted in a plate-shaped iron-rich phase.High-density stacking fault inβphase andδ/βinterface provided an excellent nucleation site forδphase.From mechanical behavior,the stress concentration caused by eutectic iron-rich phases was far less than(P-ImC)_(I) and it would not cause crack initiation along the eutectic cluster boundary.In addition,(P-ImC)_(I) showed the worst deformation coordination with primaryα-Al while the plate-shaped eutectic iron-rich phase exhibited similar deformation characteristics with silicon particles.

关键词： Alsi10mnmg High-pressure die casting multiple iron-rich phases

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Correlation between Porosity and Fracture mechanism in High Pressure Die Casting of Am60B Alloy

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Journal of materials science & Technology 2016年第1期32卷 54-61页

作者： X.Li s.m.xiong Z.Guo school of materials science and Engineering Tsinghua University state Key Laboratory of Automobile safety and Energy Tsinghua University

X-ray tomography was used to characterize the porosity in high pressure die casting of Am60B alloy. In situ tensile deformation was performed to observe the change of porosities and their influences on crack initiation, propagation and subsequent fracture of specimen. Results showed that four types of porosi- ties, including gas-shrinkage pore, gas pore, net-shrinkage and island-shrinkage, could be identified according to the formation mechanism and morphology characterization. During tensile deformation, it was shown that the gas-shrinkage pore and net-shrinkage, rather than gas pore or island-shrinkage, were the main sources for crack initiation. In addition, the crack propagated by interconnecting the po- rosities at the cross section with minimum efficient force bearing area. At these locations where externally solidified crystals （EsCs） were present, the crack would propagate along the EsC boundaries in an inter- granular mode, while at these locations without EsCs, the crack would propagate roughly along the direction perpendicular to the tensile stress in a combination of trans-granular and inter-granular modes.

关键词： High pressures die casting Am60B alloy Fracture mechanism Porosity

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A Dual Yamabe Flow and Related Integral Flows

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Chinese Annals of mathematics,series B 2024年第3期45卷 319-348页

作者： Jingang xiong school of mathematical sciences Laboratory of Mathematics and Complex Systems Ministry of Edu-cation Beijing Normal University

The author studies a family of nonlinear integral flows that involve Riesz potentials on Riemannian manifolds. In the Hardy-Littlewood-sobolev (HLs for short)subcritical regime, he presents a precise blow-up profile exhibited by the flows. In the HLs critical regime, by introducing a dual Q curvature he demonstrates the concentrationcompactness phenomenon. If, in addition, the integral kernel matches with the Green’s function of a conformally invariant elliptic operator, this critical flow can be considered as a dual Yamabe flow. Convergence is then established on the unit spheres, which is also valid on certain locally conformally flat manifolds.

关键词： Hardy-Littlewood-sobolev functional Dual Q curvature Integral flow 45K05 35B33

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Long non-coding RNAs with essential roles in neurodegenerative disorders

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Neural Regeneration Research 2024年第6期19卷 1212-1220页

作者： Wandi xiong Lin Lu Jiali Li Key Laboratory of Animal models and Human Disease mechanisms of Chinese Academy of sciences & Yunnan Province Kunming Institute of Zoology the Chinese Academy of Sciences Tsinghua-Peking Center for Life sciences National Institute on Drug Dependence Peking University PKU/mcGovern Institute for Brain Research Peking University Institute of mental Health National Clinical Research Center for Mental Disorders Key Laboratory of Mental Health and Peking University Sixth Hospital Peking University

Recently, with the advent of high-resolution and high-throughput sequencing technologies, an increasing number of long non-coding RNAs(lncRNAs) have been found to be involved in the regulation of neuronal function in the central nervous system with specific spatiotemporal patterns, across different neurodegenerative diseases. However, the underlying mechanisms of lncRNAs during neurodegeneration remain poorly understood. This review provides an overview of the current knowledge of the biology of lncRNAs and focuses on introducing the latest identified roles, regulatory mechanisms, and research status of lncRNAs in Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and amyotrophic lateral sclerosis. Finally, this review discusses the potential values of lncRNAs as diagnostic biomarkers and therapeutic targets for neurodegenerative diseases, hoping to provide broader implications for developing effective treatments.

关键词： Alzheimer’s disease amyotrophic lateral sclerosis biomarker Huntington’s disease long non-coding RNAs neurodegenerative diseases Parkinson’s disease therapy transcriptional regulation translational regulation

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Recent Progress in Bionic Hydrogels for Articular Cartilage:Tribological and mechanical Characteristics

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Journal of Bionic Engineering 2024年第2期21卷 653-673页

作者： mohammad Javan Almasi Dangsheng xiong school of materials science and Engineering Nanjing University of Science and TechnologyNanjing210094China

Cartilage regeneration and repair are considered clinical challenges since cartilage has limited capability for reconstruction.Although tissue-engineered materials have the ability to repair cartilage,they have weak mechanical characteristics and cannot resist long-term overload.On the other hand,surgery to replace the joint is frequently done to treat significant cartilage deterioration these days.However,the materials that are being used for replacement have high friction coefficients,lack shock absorption functions,and lack cushioning.Further research on natural articular cartilage structure and function may lead to bionic hydrogels,which have suitable physicochemical and biological characteristics(e.g.,tribological and mechanical properties and the ability to support loadbearing capability),but need improvements.Based on their tribological and mechanical characteristics,the current review highlights the most recent advancements of bionic hydrogels used for articular cartilage,highlighting both the field's recent progress and its potential for future research.For this reason,firstly,some important property improvement methods of bionic hydrogels are discussed and then,the recent findings of various research on the making of those bionic materials are provided and compared.It seems that by using some modifications such as product design,surface treatments,animal tests,controlling the isoelectric point of hydrogels,and computer simulation,the intended mechanical and tribological characteristics of natural articular cartilage may be attained by the bionic hydrogels.

关键词： Bionic hydrogel Articular cartilage mechanical property Tribological property Lubrication

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Integrated Zoology’s collection of Wildlife Diseases Research Network

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Integrative Zoology 2024年第3期19卷 348-349页

作者： Wenhua xiong Institute of Zoology Chinese Academy of Sciences Office of the International society of Zoological sciences

The International society of Zoological sciences has developed a Wildlife Diseases Research Network(WDRN)in the world,with the collaboration of its partners such as the Working Group on Zoonotic Disease of the International Union of Biological sciences(IUBs)(https://***/).WDRN is composed of a steering committee,a scientific committee,a research expert network,and collaborative partners.

关键词： partner committee IUB

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Hole mobility enhancement in monolayer Wse2 p-type transistors through molecular doping

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science China(Information sciences) 2024年第6期67卷 207-213页

作者： shiyuan LIU xiong xiong Xin WANG Xinhang sHI Ru HUANG Yanqing WU school of Integrated Circuits and Beijing Advanced Innovation Center for Integrated Circuits Peking University Wuhan National High magnetic Field Center and school of Integrated Circuits Huazhong University of Science and Technology

Two-dimensional （2D） transition metal dichalcogenide （TmDC） semiconductor materials exhibit extraordinary electrical properties,holding promise for the realization of next-generation complementary metal-oxide-semiconductor （CmOs） devices at ultimate scaling.However,constrained by effective device doping strategies,the hole mobility and device performance of tungsten diselenide （Wse2） p-type transistors,especially monolayer chemical vapor deposition （CVD）-grown Wse2,have not met expectations.In this paper,an effective performance enhancement of monolayer Wse2p-type transistor was achieved through a molecular doping strategy.synthesizing monolayer Wse2directly on siO2back-gated substrates and leveraging energy band alignment design,4-nitrobenzenediazonium tetrafluoroborate （4-NBD） molecular dopant with a concentration of 10 m m was utilized to modulate the Fermi level position of monolayer Wse2for hole doping.The devices demonstrated a more than 98%increase in hole mobility,reaching up to 97 cm2·V-1·s-1while maintaining the current on/off ratio of 108.monolayer p-type Wse2transistors with 1μm channel length exhibit a high drive current surpassing 176μA·μm-1,exceeding previous CVD-Wse2devices with similar channel length.This straightforward and effective approach to improving the electrical performance of Wse2transistors paves the way for advanced logic technologies based on transition metal dichalcogenide semiconductors.

关键词： CVD-grown Wse$_2$ molecular doping 4-NBD p-type transistors hole mobility

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mesenchymal stem cell-derived extracellular vesicles as a cell-free therapy for traumatic brain injury via neuroprotection and neurorestoration

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Neural Regeneration Research 2024年第1期19卷 49-54页

作者： Ye xiong Asim mahmood michael Chopp Department of Neurosurgery Henry Ford HospitalDetroitMIUSA Department of Neurology Henry Ford HospitalDetroitMIUSA Department of Physics Oakland UniversityRochesterMIUSA

Traumatic brain injury is a serious and complex neurological condition that affects millions of people worldwide.Despite significant advancements in the field of medicine,effective treatments for traumatic brain injury remain limited.Recently,extracellular vesicles released from mesenchymal stem/stromal cells have emerged as a promising novel therapy for traumatic brain injury.Extracellular vesicles are small membrane-bound vesicles that are naturally released by cells,including those in the brain,and can be engineered to contain therapeutic cargo,such as anti-inflammatory molecules,growth factors,and microRNAs.When administered intravenously,extra cellular vesicles can cross the blood-brain barrier and deliver their cargos to the site of injury,where they can be taken up by recipient cells and modulate the inflammatory response,promote neuroregeneration,and improve functional outcomes.In preclinical studies,extracellular vesicle-based therapies have shown promising results in promoting recove ry after traumatic brain injury,including reducing neuronal damage,improving cognitive function,and enhancing motor recovery.While further research is needed to establish the safety and efficacy of extra cellular vesicle-based therapies in humans,extra cellular vesicles represent a promising novel approach for the treatment of traumatic brain injury.In this review,we summarize mesenchymal ste m/stromal cell-de rived extracellular vesicles as a cell-free therapy for traumatic brain injury via neuroprotection and neurorestoration and brainderived extracellular vesicles as potential biofluid biomarkers in small and large animal models of traumatic brain injury.

关键词： biomarkers extracellular vesicles functional outcome mesenchymal stem/stromal cells neuroinflammation neuroplasticity neuroprotection traumatic brain injury

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Probing the interseismic locking state of the Xianshuihe fault based on a viscoelastic deformation model

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science China Earth sciences 2024年第1期67卷 134-145页

作者： Yage ZHU Faqi DIAO Fei CHEN Yuebing WANG Zhigang sHAO Rongjiang WANG xiong xiong Hubei subsurface multi-scale Imaging Key Laboratory School of Geophysics and GeomaticsChina University of GeosciencesWuhan 430074China China Earthquake Networks Center Beijing 100045China Institute of Earthquake Forecasting China Earthquake AdministrationBeijing 100036China

The interseismic locking state of tectonic faults is essential for regional seismic hazard assessments.However,it is challenging to obtain this parameter reliably due to the weak deformation and complex model configurations.To better probe the fault locking state,more reliable physical models and well-covered observations are required.Here we investigate the locking state of the Xianshuihe fault based on a new-developed viscoelastic deformation model.meanwhile,we combine GPs velocities from 13 new near-field stations and existing stations in this region to improve the spatial resolution.similar to the theoretical predictions,our results indicate that the elastic model will clearly overestimate the fault locking depth and seismic moment accumulation rate,and the fault slip rate inferred from the elastic model is slightly lower than that from the viscoelastic model.Relying on the locking distribution inferred from the viscoelastic model,we identify four potential asperities on the Xianshuihe fault.more importantly,we find a clear spatial correlation between the fault locking distribution and the rupture extent of historical earthquakes,which indicates that the fault locking state may control the rupture extent and thus the magnitude of earthquakes.In addition,our results show that the 2022 m6.8 Luding earthquake only ruptured the south part of a potential asperity,and the accumulated energy in the northern unruptured area is equivalent to an mw6.9 earthquake,where the seismic hazard deserves special attention.

关键词： Fault kinematics Viscoelastic relaxation effect GPs observations seismic hazard The 2022 m6.8 Luding earthquake

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multi-layer hierarchical cellulose nanofibers/carbon nanotubes/vinasse activated carbon composite materials for supercapacitors and electromagnetic interference shielding

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Nano Research 2024年第3期17卷 904-912页

作者： Tianxu Wang Chuanyin xiong Yongkang Zhang Bo Wang Qing xiong mengjie Zhao Yonghao Ni College of Bioresources Chemical&materials Engineering Shaanxi University of Science and TechnologyXi’an 710021China Department of Chemical and biomedical Engineering The University of MaineOronoME 04469USA University of New Brunswick Limerick Pulp&Paper CtrFrederictonNB E3B 5A3Canada

Developing porous self-supporting electrodes with excellent conductivity,good mechanical properties,and high electrochemical activity is crucial for constructing electrode materials with lightweight,ultra-thin,flexible,and high capacitance performance.In this work,we prepared a cellulose nanofibers(CNFs)/carbon nanotubes(CNTs)/vinasse activated carbon(VAC)(CCV)composite material with a multi-layer hierarchical conductive structure through simple vacuum filtration and freeze-drying.In this composite material,the self-assembly of CNF provides the main skeleton structure of a multi-layer hierarchical structure.CNT provides a fast path for the rapid transfer of electrons and is beneficial for the loss of electromagnetic waves.VAC provides sufficient double layer performance.The synergistic effect of the above three endows CCV composite materials with excellent energy storage performance and electromagnetic interference(EmI)shielding performance.In addition,we endowed the CCV composite with a certain shape and performance by introducing a vitrimer polymer with a dynamic cross-linked network structure.In summary,thanks to the synergistic effect of various components in the multi-layer hierarchical structure,CCV composite materials exhibit excellent integration performance,especially stable energy storage performance and EmI shielding performance.These significant properties make CCV composite materials have great application prospects in the fields of energy storage and intelligent EmI shielding.

关键词： self-supporting electrodes multi-layer hierarchical structure supercapacitors electromagnetic interference shielding

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