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Exclusive Population of n=2 s-states in He-like Uranium by Ionization Process

近代物理研究所和兰州重离子加速器实验室年报：英文版 2002年第1期 76-76页

作者： Ma Xinwen D.Banas Th.sthlker H.F.Beyer F.Bosch A.Br(?)uning-Demian A.Gumberidze s.hagmann C.Kozhuharov P.H.Mokler R.Mann A.Orsic Muthig D.sierpowski U.spillmann s.Tachenov Z.stachura A.Warczak Gesellschaft fiir schwerionenforschung Darmstadt Germany.Gesellschaft fur SchwerionenforschunK Darmstadt Germany. Institute of Physics Swietokrzyslta Academy Kielce Poland.Gesellschaft fur Schwerlonenforschung Darmstadt Germany. Institute fur Kerrtphysik University of Frankfurt Germany.Gesellschaft fur Schwerionenforschung Darmstadt Germany.Gesellschaft fur Schwerionenforschung Darmstadt Germany.Gesellschaft fur Schwerionenforschung Darmstadt Germany.Gesellschaft fur Schwerionenforschung Darmstadt Germany. Institute fur Kernphysik University of Frankfurt Germany.Tbilisi State University Georgia.Gesellschaft fur Schwerionenforschung Darmstadt Germany.Gesellschaft fur Schwerionenforschung Darmstadt Germany.Gesellschaft fur Schwerionenforschung Darmstadt Germany.Gesellschaft fur Schwerionenforschung Darmstadt Germany.Gesellschaft fur Schwerionenforschung Darmstadt Germany. Institute fur Kerntphysik University of Frankfurt Germany.Gesellschaft fur Schwerionenforschung Darmstadt Germany. Institute of Physics Jagiellonian University Cracow Poland.Gesellschaft fur Schwerionenforschung Darmstadt Germany. Institute fur Kerrtphysik University of Frankfurt Germany.Gesellschaft fur Schwerionenforschung Darmstadt Germany. Institute fur Kerrtphysik University of Frankfurt Germany.Gesellschaft fur Schwerionenforschung Darmstadt Germany.Institute of Nuclear Studies Cracow Ppland.Gesellschaft fur Schwerionenforschung Darmstadt Germany. Institute of Physics Jagiellonian University Cracow Poland.

K-shell ionization for Li-like uranium ions in collisions with a N2 target was performed at the EsR storage ring. We found surprisingly that in such close encounters the 2 s electron remain almost unaffected by the collisions. A dedicated experimental study was conducted by using Li-like uranium ions at an initial energy of 378 MeV/u in order to manifest the situation. In Fig.1 a typical spectrum is shown registered by a Ge(i)

关键词：碰撞电离类氦铀离子超选择布居 s态原子物理学 X射线衍射光谱分析辐射强度

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Exclusive Population of n=2 s-states in He-like Uranium by Ionization Process

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IMP & HIRFL Annual Report 2002年 76-76页

作者： Ma Xinwen,D.Banas,Th.sthlker,H.F.Beyer,F.Bosch,A.Br(?)uning-Demian,A.Gumberidze,s.hagmann,C.Kozhuharov,P.H.Mokler,R.Mann,A.Orsic Muthig,D.sierpowski,U.spillmann,s.Tachenov,Z.stachura,A.Warczak Gesellschaft fiir schwerionenforschung Darmstadt Germany. Gesellschaft fur schwerionenforschunK Darmstadt Germany. Institute of Physics swietokrzyslta Academy Kielce Poland. Gesellschaft fur schwerlonenforschung Darmstadt Germany. Institute fur Kerrtphysik University of Frankfurt Germany. Gesellschaft fur schwerionenforschung Darmstadt Germany. Gesellschaft fur schwerionenforschung Darmstadt Germany. Gesellschaft fur schwerionenforschung Darmstadt Germany. Gesellschaft fur schwerionenforschung Darmstadt Germany. Institute fur Kernphysik University of Frankfurt Germany. Tbilisi state University Georgia. Gesellschaft fur schwerionenforschung Darmstadt Germany. Gesellschaft fur schwerionenforschung Darmstadt Germany. Gesellschaft fur schwerionenforschung Darmstadt Germany. Gesellschaft fur schwerionenforschung Darmstadt Germany. Gesellschaft fur schwerionenforschung Darmstadt Germany. Institute fur Kerntphysik University of Frankfurt Germany. Gesellschaft fur schwerionenforschung Darmstadt Germany. Institute of Physics Jagiellonian University Cracow Poland. Gesellschaft fur schwerionenforschung Darmstadt Germany. Institute fur Kerrtphysik University of Frankfurt Germany. Gesellschaft fur schwerionenforschung Darmstadt Germany. Institute fur Kerrtphysik University of Frankfurt Germany. Gesellschaft fur schwerionenforschung Darmstadt Germany. Institute of Nuclear studies Cracow Ppland. Gesellschaft fur schwerionenforschung Darmstadt Germany. Institute of Physics Jagiellonian University Cracow Poland.

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Resonant Transfer and Excitation study for Hydrogen-like Uranium Ions

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IMP & HIRFL Annual Report 2001年第1期 85-85页

作者： P.H.Mokler G.Bednarz F.Bosch A.Gumberidze s.hagmann C.Kozhuharov D.liesen U.Popp D.sierpowski Z.stachura Th.sthlken s.Tashennov s.Toleikis A.Warczak GsI Darmstadt Germanv.Jagiellonian UnivCracowPoland.GST DarmstadtGermany.GST DarmstadtGermany.GST DarmstadtGermany.GST DarmstadtGermany.GST DarmstadtGermany.GST DarmstadtGermany.Jagiellonian Univ.CracowPoland.IFJ.CracowPoland.GSI DarmstadtGermany.State Univ.MoscowRussia.GSI DarmstadtGermany.Jagiellonian Univ.CracowPoland.

He-like ions are the simplest atomic system where the electron-electron interactions can be studied without any disturbance by further correlations. For heavy atomic systems the structure and dynamics differ significantly from those of light ions, and in this relativistic domain the current or magnetic interactions play an

关键词： relativistic Hydrogen disturbance excited switched uranium coincidence sketch initially interacting

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Resonant Transfer and Excitation study for Hydrogen-like Uranium Ions

引用

IMP & HIRFL Annual Report 2001年 85-85页

作者： P.H.Mokler,G.Bednarz,F.Bosch,A.Gumberidze,s.hagmann,C.Kozhuharov,D.liesen,U.Popp,D.sierpowski,Z.stachura,Th.sthlken,s.Tashennov,s.Toleikis,A.Warczak GsI Darmstadt Germanv. Jagiellonian Univ Cracow Poland. GsT Darmstadt Germany. GsT Darmstadt Germany. GsT Darmstadt Germany. GsT Darmstadt Germany. GsT Darmstadt Germany. GsT Darmstadt Germany. Jagiellonian Univ.Cracow Poland. IFJ.Cracow Poland. GsI Darmstadt Germany. state Univ.Moscow Russia. GsI Darmstadt Germany. Jagiellonian Univ.Cracow Poland.

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Polarization Measurements in Radiative Electron Capture into High-Z Ions

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近代物理研究所和兰州重离子加速器实验室年报：英文版 2002年第1期 77-77页

作者： F.Bosch A.Gumberidze s.hagmann C.Kozhuharov Th.Krings A.OrsicMuthig D.Protic D.sierpowski U.spillmann Z.stachura A.Warczak MaXinwen s.Tachenov Th.stoehlker D.Banas H.F.Beyer GsI-Darmstadt Germany. IKF UniversityofFrankfurtGermany. KansasstateUniversity USA. InstituteofPhysics CracowUniversityPoland. INP CracowPoland. InstituteofPhysicsswietokrzyakaAcademy KielcePoland. TbilislstateUniversity Georgia. FZ-3urich Germany. 不详

Recently, there has been great interest in the linear polarization of photons produced by radiative electron capture (REC, the time reversed photoionization in ion-atom collisions). No such data are available for the high-Z regime till now. By using high efficiency by by a new generation of segmented germanium detectors that have energy as well as position resolution this field can be investigated experimentally. The

关键词：高电荷态离子俘获电子辐射极化测量散射截面观测角原子物理学能量谱

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Polarization Measurements in Radiative Electron Capture into High-Z Ions

引用

IMP & HIRFL Annual Report 2002年 77-77页

作者： s.Tachenov,Th.sthlker,D.Banas,H.F.Beyer,F.Bosch,A.Gumberidze,s.hagmann,C.Kozhuharov,Th.Krings,A.Orsic Muthig,D.Protic,D.sierpowski,U.spillmann,Z.stachura,A.Warczak GsI-Darmstadt Germany.IKF University of Frankfurt Germany. GsI-Darmstadt Germany.IKF University of Frankfurt Germany. GsI-Darmstadt Germany.Institute of Physics swietokrzyska Academy Kielce Poland. GsI-Darmstadt Germany. GsI-Darmstadt Germany. GsI-Darmstadt Germany.IKF University of Frankfurt Germany.Tbilisi state University Georgia. GsI-Darmstadt Germany. Kansas state University UsA. GsI-Darmstadt Germany. FZ-J ulich Germany. GsI-Darmstadt Germany.IKF University of Frankfurt Germany. FZ-J ulich Germany. Institute of Physics Cracow University Poland. GsI-Darmstadt Germany.IKF University of Frankfurt Germany. INP Cracow Poland. Institute of Physics Cracow University Poland.

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Two-electron QED studies for Helium-like Uranium

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近代物理研究所和兰州重离子加速器实验室年报：英文版 2002年第1期 75-75页

作者： MaXinwen Th.stoehlker A.Gumberidze H.F.Beyer G.Bednarz F.Bosch CaiXiaohong s.Fritzsche s.hagmann C.Kozhuharov O.Klepper D.Liesen P.H.Mokler D.sierpowski Z.stachura M.steck A.surzhykov s.Toleikis A.Warczak Y.Zou 不详 GsI-Darmstadt Germany. IKF UniversityofFrankfurtGermany InstituteofPhysics CracowUniversityPoland. UniversityofKassel Germany. KansasstateUniversity KansasUSA. INP CracowPoland. FudauUniversity ShanghaiChina.

The study of structure of few-electron heavy ions is of important interest due to the strong field effects. Helium-like ions are the simplest atomic multi-body systems. A considerable improved precision has been made in both theory and experiments recently. The experiment exploits the radiative recombination (RR) transitions into the vacant 1 s shell of bare and H-like ions. In this process, the energy carried by the emitted photon is the energy difference between the initial and final electron state, hω=Ekin+EB. For bare

关键词：类氦铀离子双电子QED效应强场作用少电子重离子结构研究原子物理学基态电子冷却电子

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Revisiting cerebral endothelial cells in Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2911-2912页

作者： Amira s.Hanafy Department of Neurosurgery University Hospital BonnBonnGermany

Alzheimer’s disease(AD)is the most common neurodegenerative disorder characterized by slow and progressive decline of cognitive and memory *** only approximately 5%of the cases,AD is familial,as often predisposed by genetic mutations(Hoogmartens et al.,2021),while sporadic AD accounts for approximately 95%of the *** amyloid cascade hypothesis is one of the fundamental hypotheses put out to explain AD pathogenesis as dysregulated homeostasis of amyloid-β(Aβ)peptides that leads to the accumulation of Aβplaques in the parenchyma,an anatomical hallmark of AD.

关键词： Alzheimer Aβ cerebral

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Two-electron QED studies for Helium-like Uranium

引用

IMP & HIRFL Annual Report 2002年 75-75页

作者： Th.sthlker,A.Gumberidze,H.F.Beyer,G.Bednarz,F.Bosch,s.Fritzsche,s.hagmann,C.Kozhuharov,O.Klepper,D.Liesen,P.H.Mokler,D.sierpowski,Z.stachura,M.steck,A.surzhykov,s.Toleikis,A.Warczak,Y.Zou GsI-Darmstadt Germany.IKF University of Frankfurt Germany. GsI-Darmstadt Germany. IKF University of Frankfurt Germany. Tbilisi states University Georgia. GsI-Darmstadt Germany. Institute of Physics Cracow University Poland. GsI-Darmstadt Germany. University of Kassel Germany. GsI-Darmstadt Germany.Kansas state University Kansas UsA. GsI-Darmstadt Germany. GsI-Darmstadt Germany. GsI-Darmstadt Germany. GsI-Darmstadt Germany. Institute of Physics Cracow University Poland. INP Cracow Poland. GsI-Darmstadt Germany. Kansas state University Kansas UsA. GsI-Darmstadt Germany. Institute of Physics Cracow University Poland. Fudan University shanghai China.

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Emerging structures and dynamic mechanisms ofγ-secretase for Alzheimer’s disease

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Neural Regeneration Research 2025年第1期20卷 174-180页

作者： Yinglong Miao Michael s.Wolfe Computational Medicine Program and Department of Pharmacology University of North Carolina–Chapel HillChapel HillNCUSA Department of Medicinal Chemistry University of KansasLawrenceKSUSA

γ-secretase,called“the proteasome of the membrane,”is a membrane-embedded protease complex that cleaves 150+peptide substrates with central roles in biology and medicine,including amyloid precursor protein and the Notch family of cell-surface *** inγ-secretase and amyloid precursor protein lead to early-onset familial Alzheimer’s disease.γ-secretase has thus served as a critical drug target for treating familial Alzheimer’s disease and the more common late-onset Alzheimer’s disease as ***,critical gaps remain in understanding the mechanisms of processive proteolysis of substrates,the effects of familial Alzheimer’s disease mutations,and allosteric modulation of substrate cleavage byγ-*** this review,we focus on recent studies of structural dynamic mechanisms ofγ-*** mechanisms,including the“Fit-stay-Trim,”“sliding-Unwinding,”and“Tilting-Unwinding,”have been proposed for substrate proteolysis of amyloid precursor protein byγ-secretase based on all-atom molecular dynamics *** an incorrect registry of the Notch1 substrate was identified in the cryo-electron microscopy structure of Notch1-boundγ-secretase,molecular dynamics simulations on a resolved model of Notch1-boundγ-secretase that was reconstructed using the amyloid precursor protein-boundγ-secretase as a template successfully capturedγ-secretase activation for proper cleavages of both wildtype and mutant Notch,being consistent with biochemical experimental *** approach could be potentially applied to decipher the processing mechanisms of various substrates byγ-*** addition,controversy over the effects of familial Alzheimer’s disease mutations,particularly the issue of whether they stabilize or destabilizeγ-secretase-substrate complexes,is ***,an outlook is provided for future studies ofγ-secretase,including pathways of substrate binding and product release,effects of modulators on familial Alzheimer’s disease mutations

关键词： Alzheimer’s disease amyloid precursor protein cryo-EM structures drug design intramembrane proteolysis molecular dynamics Notch

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