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Neural Regeneration Research 2024年第3期19卷 489-490页

作者： Boyoung lee hyun Joo An center for cognition and sociality Institute for Basic Science(IBS)DaejeonSouth Korea Asia-Pacific Glycomics Reference site DaejeonSouth Korea Graduate school of Analytical science&Technology Chungnam National UniversityDaejeonSouth Korea

Glycosylation is a process that involves the addition of sugar moieties or glycans to different types of molecules,including proteins,lipids,and nucleic *** these,protein glycosylation is one of the most prevalent forms of post-translational modification,playing a crucial role in biological *** more than ten monosaccharides identified within mammalian brain cells and more than 1×1012 possible combinations,the heterogeneity of glycosylation is extensive(conroy et al.,2021).The diversity of glycans and the complexity of their structures allow for a wide range of protein functions.N-glycans are one of the most abundant forms of glycans and are involved in various cellular functions.N-glycans can be added to proteins at specific sequons,Asn-X-ser/Thr,and are classified into three main types in mature glycoproteins:high mannose,complex,and *** mannose N-glycans consist of 5-9 mannose residues linked to a chitobiose core and undergo processing into complex or hybrid forms in the Golgi apparatus(Varki et al.,2017).complex N-glycans are more diverse and contain various branched structures such as antennae with fucose,galactose,and sialic acid *** N-glycans contain one or more complex branches in conjunction with an oligomannose branch(fisher and Ungar,2016).Understanding the specific functions of these different types of N-glycans in protein regulation,folding,and function is an active area of research in the life sciences,including glycobiology.

关键词： functions function apparatus

failure to Rescue as a Quality Metric in congenital heart surgeries in a high-complexity service Provider Institution Located in a Middle-Income country

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congenital heart Disease 2024年第2期19卷 207-218页

作者： Gustavo cruz santiago Pedroza Juan f.Vélez Jessica Largo Juan f.Tejada Jorge h.Mejía-Mantilla Departamento de Anestesiología Fundación Valle del LiliCali760032Colombia centro de Investigaciones clínicas Fundación Valle del LiliCali760032Colombia Departamento de cardiología Pediátrica Fundación Valle del LiliCali760032Colombia facultad de Medicina Universidad IcesiCali760031Colombia Unidad de cuidado Intensivo Fundación Valle del LiliCali760032Colombia

Background:failure to rescue has been an effective quality metric in congenital heart ***,mor-bidity and mortality depend greatly on non-modifiable individual factors and have a weak correlation with better-quality *** aim to measure the complications,mortality,and risk factors in pediatric patients undergoing congenital heart surgery in a high-complexity institution located in a middle-income country and compare it with other institutions that have conducted a similar ***:A retrospective observational study was conducted in a high-complexity service provider institution,in cali,*** pediatric patients undergoing any congenital heart surgery between 2019 and 2022 were *** main outcomes evaluated in the study were complication,mortality,and failure to rescue *** and multivariate logistic regression analysis was performed with mortality as the outcome ***:We evaluated 308 congenital heart *** the outcomes,201(65%)complications occurred,23(7.5%)patients died,and the fTR of the entire cohort was 11.4%.The presence of a postoperative complication(OR 14.88,cI 3.06–268.37,p=0.009),age(OR 0.79,cI 0.57–0.96,p=0.068),and urgent/emergent surgery(OR 8.14,cI 2.97–28.66,phe most significant variables in predicting ***:failure to rescue is an effective and comparable quality measure in healthcare institutions and is the major contributor to postoperative mortality in congenital heart *** our higher mortality and complication rate,we obtained a comparable failure to rescue rate to high-income countries’health institutions.

关键词： congenital heart surgery complication mortality failure to rescue quality metric

Novel Rifle Number Recognition Based on Improved YOLO in Military Environment

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computers, Materials & continua 2024年第1期78卷 249-263页

作者： hyun Kwon sanghyun lee Department of Artificial Intelligence and Data science Korea Military AcademySeoulKorea Graduate school of Information security Korea Advanced Institute of Science and TechnologyDaejeonKorea

Deep neural networks perform well in image recognition,object recognition,pattern analysis,and speech *** military applications,deep neural networks can detect equipment and recognize *** military equipment,it is necessary to detect and recognize rifle management,which is an important piece of equipment,using deep neural *** have been no previous studies on the detection of real rifle numbers using real rifle image *** this study,we propose a method for detecting and recognizing rifle numbers when rifle image data are *** proposed method was designed to improve the recognition rate of a specific dataset using data fusion and transfer *** the proposed method,real rifle images and existing digit images are fusedas trainingdata,andthe final layer is transferredto theYolov5 *** detectionand recognition performance of rifle numbers was improved and analyzed using rifle image and numerical *** used actual rifle image data(K-2 rifle)and numeric image datasets,as an experimental *** was used as the machine learning *** results show that the proposed method maintains 84.42% accuracy,73.54% precision,81.81% recall,and 77.46% f1-score in detecting and recognizing rifle *** proposed method is effective in detecting rifle numbers.

关键词： Machine learning deep neural network rifle number recognition detection

Amorphous BaTiO_(3) Electron Transport Layer for Thermal Equilibrium-Governed γ-csPbl_(3) Perovskite solar cell with high Power conversion Efficiency of 19.96%

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Energy & Environmental Materials 2024年第3期7卷 291-302页

作者： changhyun lee chanyong lee Kyungjin chae Taemin Kim seaeun Park Yohan Ko Yongseok Jun Department of Energy Environment Policy and Technology Graduate School of Energy and Environment(KU-KIST Green School)Korea UniversitySeoul 02841Republic of Korea Nano Electronic Materials and components Research center Gumi Electronics and Information Technology Research Institute(GERI)Gumi 39171Republic of Korea Energy Materials Research center Clean Energy Research DivisionKorea Institute of Science and Technology(KIST)Seoul 02792Republic of Korea

compared to organic-inorganic hybrid perovskites,the cesium-based allinorganic lead halide perovskite(csPbI_(3))is a promising light absorber for perovskite solar cells owing to its higher resistance to thermal ***,additional research is required to reduce the nonradiative recombination to realize the full potential of csPbI_(3).here,the diffusion of cs ions participating in ion exchange is proposed to be an important factor responsible for the bulk defects inγ-csPbI_(3)*** based on first-principles density functional theory reveal that the[PbI_(6)]^(4-)octahedral tilt modifies the perovskite crystallographic properties inγ-csPbI_(3),leading to alterations in its bandgap and crystal *** addition,by substituting amorphous barium titanium oxide(a-BaTiO_(3))for TiO_(2)as the electron transport layer,interfacial defects caused by imperfect energy levels between the electron transport layer and perovskite are ***-resolution transmission electron microscopy and electron energy loss spectroscopy demonstrate that a-BaTiO_(3)forms entirely as a single phase,as opposed to Ba-doped TiO_(2)hybrid nanoclusters or separate domains of TiO_(2)and BaTiO_(3)***,inorganic perovskite solar cells based on the a-BaTiO_(3)electron transport layer achieved a power conversion efficiency of 19.96%.

关键词： amorphous BaTiO_(3) electron transport layer moisture γ-csPbI_(3)

search for production of dark fermion candidates in association with heavy neutral gauge boson decaying to dimuon in proton-proton collisions at√s=8 TeV using cMs open data

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chinese Physics c 2024年第4期48卷 6-13页

作者： Y.Mahmoud h.Abdallah M.T.hussein s.Elgammal centre for theoretical physics The British University in EgyptEgypt Physics Department Faculty of ScienceCairo UniversityEgypt

In this study,we conducted a search for dark matter using a part of the data recorded by the cMs experiment during run-I of the Lhc in 2012 with a center of mass energy of 8 TeV and an integrated luminosity of 11.6 fb−*** data were gathered from the cMs open *** matter,in the framework of the simplified model(mono-Z′),can be produced from proton-proton collisions in association with a new hypothetical gauge boson,Z′.Thus,the search was conducted in the dimuon plus large missing transverse momentum *** benchmark scenario of mono-Z′,which is known as light vector,was used for interpreting the cMs open *** evidence of dark matter was observed,and exclusion limits were set on the masses of dark matter and Z′at 95%confidence level.

关键词： dark matter large hadron collider cMs open data search for new physics dark fermion

Model dependent analysis of ■→■ decays in beyond standard model

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chinese Physics c 2024年第9期48卷 86-99页

作者： s.Mahata M.Mandal h.Mahapatra s.Biswas s.sahoo Department of Physics National Institute of Technology Durgapur

Motivated by the recent experimental results of branching fractions for ■→■ decays,which deviate from their sM predictions,we hve investigated these decays in W' model and scalar leptoquark model to determine potential signatures of new physics(NP) in semileptonic charm decays induced by c→■ *** recent experimental results of branching fractions for semileptonic D meson decays,new coupling parameters are predicted for the aforementioned NP *** fraction,forward-backward asymmetry,and lepton polarization asymmetry are examined by considering the predicted NP coupling *** results of branching fractions in scalar leptoquark model are found very close to the experimental results and exist around the range of 1σ *** presented a comparative study of the NP models to check their sensitivity on these *** anticipate that further research on these decays will significantly support our findings.

关键词： $ W' $ boson charm decay flavour changing charged current new physics scalar leptoquark

Insulin therapy in type 2 diabetes: Insights into clinical efficacy, patient-reported outcomes, and adherence challenges

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World Journal of Diabetes 2024年第5期15卷 828-852页

作者： Mahmoud Emad-Eldin Gehan f Balata Eman A Elshorbagy Mona s hamed Mohamed s Attia Department of Pharmacy Practice Faculty of PharmacyZagazig UniversityZagazig HFQM+872Al-Sharqia GovernorateEgypt Department of Pharmacy Practice Faculty of PharmacyHeliopolis UniversityCairo 44519Egypt Department of Pharmaceutics Faculty of PharmacyZagazig UniversityZagazig 44519Al-Sharqia GovernorateEgypt Department of Internal Medicine Faculty of MedicineZagazig UniversityZagazig 44519Al-Sharqia GovernorateEgypt Department of community at faculty of Medicine Zagazig UniversityZagazig 44519Al-Sharqia GovernorateEgypt

Insulin therapy plays a crucial role in the management of type 2 diabetes as the disease *** the past century,insulin formulations have undergone significant modifications and bioengineering,resulting in a diverse range of available insulin *** products show distinct pharmacokinetic and pharmacodynamic ***,various insulin regimens have em-erged for the management of type 2 diabetes,including premixed formulations and combinations of basal and bolus *** utilization of different insulin regimens yields disparate clinical outcomes,adverse events,and,notably,patient-reported outcomes(PROs).PROs provide valuable insights from the patient’s perspective,serving as a valuable mine of information for enhancing healthcare and informing clinical *** to insulin therapy,a critical patient-reported outcome,significantly affects clinical outcomes and is influenced by multiple *** review provides insights into the clinical effectiveness of various insulin preparations,PROs,and factors impacting insulin therapy adherence,with the aim of enhancing healthcare practices and informing clinical decisions for individuals with type 2 diabetes.

关键词： Adherence Diabetes Insulin Patient-reported outcomes Pharmacokinetic Pharmacodynamic

Towards efficient strain engineering of 2D materials:A four-points bending approach for compressive strain

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Nano Research 2024年第6期17卷 5317-5325页

作者： hao Li félix carrascoso Ana Borrás Gloria P.Moreno francisco J.Aparicio Ángel Barranco Andrés castellanos Gómez campus de cantoblanco Instituto de Ciencia de Materiales de MadridC.Sor Juana Inés de la Cruz328049 MadridSpain Nanotechnology on surfaces and Plasma Lab Instituto de Ciencia de Materiales de Sevilla(CSIC-Universidad de Sevilla).C/Americo Vespucio 49E-41092 SevilleSpain Departamento de física Aplicada I Escuela Politécnica SuperiorUniversidad de Sevillac/Virgen deÁfrica 7E-41011 SevilleSpain

strain engineering,as a powerful strategy to tune the optical and electrical properties of two-dimensional(2D)materials by deforming their crystal lattice,has attracted significant interest in recent years.2D materials can sustain ultra-high strains,even up to 10%,due to the lack of dangling bonds on their surface,making them ideal brittle *** remarkable mechanical resilience,together with a strong strain-tunable band structure,endows 2D materials with a broad optical and electrical response upon ***,strain engineering based on 2D materials is restricted by their nanoscale and strain quantification *** this study,we have modified a homebuilt three-points bending apparatus to transform it into a four-points bending apparatus that allows for the application of both compressive and tensile strains on 2D *** approach allows for the efficient and reproducible construction of a strain system and minimizes the buckling effect caused by the van der Waals interaction by adamantane encapsulation *** results demonstrate the feasibility of introducing compressive strain on 2D materials and the potential for tuning their optical and physical properties through this approach.

关键词： uniaxial compressive strain polymer encapsulation differential reflectance spectroscopy exciton tunability

Ionizing terahertz waves with 260 MV/cm from scalable optical rectification

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Light(science & Applications) 2024年第6期13卷 1075-1087页

作者： hyeongmun Kim chul Kang Dogeun Jang Yulan Roh sang hwa lee Joong Wook lee Jae hee sung seong Ku lee Ki-Yong Kim Advanced Photonics Research Institute GISTGwangju61005Korea Department of Physics and Optoelectronics convergence Research center Chonnam National UniversityGwangju61186Korea Pohang Accelerator Laboratory POSTECHPohang37673Korea center for Relativistic Laser science Institute for Basic ScienceGwangju61005Korea Institute for Research in Electronics and Applied Physics Department of PhysicsUniversity of MarylandCollege ParkMaryland20742USA

Terahertz(Thz)waves,known as non-ionizing radiation owing to their low photon energies,can actually ionize atoms and molecules when a sufficiently large number of Thz photons are concentrated in time and ***,we demonstrate the generation of ionizing,multicycle,15-Thz waves emitted from large-area lithium niobate crystals via phase-matched optical rectification of 150-terawatt laser pulses.A complete characterization of the generated Thz waves in energy,pulse duration,and focal spot size shows that the field strength can reach up to 260 megavolts per *** particular,a single-shot Thz interferometer is employed to measure the Thz pulse duration and spectrum with complementary numerical *** intense Thz pulses are irradiated onto various solid targets to demonstrate Thz-induced tunneling ionization and plasma *** study also discusses the potential of nonperturbative Thz-driven ionization in gases,which will open up new opportunities,including nonlinear and relativistic Thz physics in plasma.

关键词： optical interferometer matched

Establishment of a chicken intestinal organoid culture system to assess deoxynivalenol‑induced damage of the intestinal barrier function

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Journal of Animal science and Biotechnology 2024年第3期15卷 1119-1130页

作者： Tae hong Kang sang In lee Department of Animal science and Biotechnology Kyungpook National UniversitySangjuGyeong‑Sangbuk‑Do 37224Republic of Korea Research Institute for Innovative Animal science Kyungpook National University37224SangjuGyeong‑Sangbuk‑DoRepublic of Korea

Background Deoxynivalenol(DON)is a mycotoxin that has received recognition worldwide because of its ability to cause growth delay,nutrient malabsorption,weight loss,emesis,and a reduction of feed intake in *** DON-contaminated feedstuff is absorbed in the gastrointestinal tract,we used chicken organoids to assess the DON-induced dysfunction of the small *** We established a culture system using chicken organoids and characterized the organoids at passages 1 and *** confirmed the mRNA expression levels of various cell markers in the organoids,such as KI67,leucine-rich repeat containing G protein-coupled receptor 5(Lgr5),mucin 2(MUc2),chromogranin A(chGA),cytokeratin 19(cK19),lysozyme(LYZ),and microtubule-associated doublecortin-like kinase 1(DcLK1),and compared the results to those of the small *** results showed that the organoids displayed functional similarities in permeability compared to the small *** damaged the tight junctions of the organoids,which resulted in increased *** Our organoid culture displayed topological,genetic,and functional similarities with the small intes-tine *** on these similarities,we confirmed that DON causes small intestine *** organoids offer a practical model for the research of harmful substances.

关键词： Barrier function Deoxynivalenol Organoids