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人乳头瘤病毒16E6与食管癌细胞核基质的关系

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癌变．畸变．突变 2002年第2期14卷 67-70页

作者：陈海滨陈玲张锦堃沈忠英苏中静 s.b.cheng E.C.Chew 汕头大学医学院肿瘤病理研究室香港中文大学生理学系香港中文大学解剖学系

目的 :观察HPV 16E6和食管癌细胞核基质的关系 ,以探讨HPV感染在食管癌变中的作用。方法 :2株食管癌细胞系 ,EC/CUHK1和EC/CUHK2 ,用于本实验。PCR扩增核基质相关的HPV 16E6亚基因片段 ,RT PCR和免疫细胞化学染色观察了E6亚基因在癌细... 详细信息

目的 :观察HPV 16E6和食管癌细胞核基质的关系 ,以探讨HPV感染在食管癌变中的作用。方法 :2株食管癌细胞系 ,EC/CUHK1和EC/CUHK2 ,用于本实验。PCR扩增核基质相关的HPV 16E6亚基因片段 ,RT PCR和免疫细胞化学染色观察了E6亚基因在癌细胞内的表达。结果 :EC/CUHK2细胞的HPV 16E6亚基因片段存在于核基质相关DNA中 ,E6癌蛋白位于核基质组分内 ;而EC/CUHK1细胞的结果均为阴性。结论 :HPV 16E6和核基质的相互作用有助于病毒导致的食管癌发生。

关键词：食管癌核基质人乳头瘤病毒

bed inventory balance and stability of dual circulating fluidized bed systems

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Particuology 2024年第1期84卷 98-106页

作者： Yangjun Wei Leming cheng David Pallares bo Leckner Institute for Thermal Power Engineering State Key Laboratory of Clean Energy UtilizationZhejiang UniversityHangzhou310027China Department of space Earth and EnvironmentChalmers University of TechnologyS-41296GöteborgSweden

Experiments and modelling are conducted for general understanding on the imbalance phenomenon and for discussion on the strategies to improve the bed inventory balance and stability of a dual circulating fluidized bed(DCFb)*** experiments are carried out in a 15.5 m high pilot-scale DCFb cold test system.A fluid-dynamic DCFb model is developed based on a 1.5-dimensional semi-empirical model of an industrial CFb boiler,validated by experimental *** effects of control methods and operation conditions on the bed inventory balance and on the stability of the pilot-and large-scale DCFb systems are discussed.A"stable-unbalanced"state,where the system reaches a steady state,consisting of un-balanced bed inventories,is observed in both experiments and model *** maintain a balanced state and similar bed inventory in the DCFb systems with similar cross-sectional areas,it is recom-mended to keep similar total pressure drops or gas velocities in both reactors.

关键词： bed inventory balance stability Dual circulating fluidized bed(DCFb) Experiment Modelling

Triple reverse order law for the Drazin inverse

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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 55-68页

作者： WANG Hua ZHONG cheng-cheng College of sciences Inner Mongolia University of TechnologyHohhot 010051China College of Engineering University of Jinan Quancheng CollegeYantai 265600China

In this paper,we investigate the reverse order law for Drazin inverse of three bound-ed linear operators under some commutation ***,the Drazin invertibility of sum is also obtained for two bounded linear operators and... 详细信息

关键词： Drazin inverse reverse order law space decomposition

Quantized autoencoder(QAE)intrusion detection system for anomaly detection in resource-constrained loT devices using RT-loT2022 dataset

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Cybersecurity 2024年第2期7卷 13-27页

作者： b s sharmila Rohini Nagapadma Depatment of Electronics and Communication Engineering The National Institute of EngineeringMysoreKarnataka 570008India

In recent years,many researchers focused on unsupervised learning for network anomaly detection in edge devices to identify *** deployment of the unsupervised autoencoder model is computationally expensive in resource-constrained edge *** study proposes quantized autoencoder(QAE)model for intrusion detection systems to detect *** is an optimization model derived from autoencoders that incorporate pruning,clustering,and integer quantization *** autoencoder uint8(QAE-u8)and quantized autoencoder float16(QAE-f16)are two variants of QAE built to deploy computationally expensive Al models into Edge ***,we have generated a Real-Time Internet of Things 2022 dataset for normal and attack *** autoencoder model operates on normal traffic during the training *** same model is then used to reconstruct anomaly traffic under the assumption that the reconstruction error(RE)of the anomaly will be high,which helps to identify the ***,we study the performance of the autoencoders,QAE-u8,and QAE-f16 using accuracy,precision,recall,and F1 score through an extensive experimental *** showed that QAE-u8 outperforms all other models with a reduction of 70.01%in average memory utilization,92.23%in memory size compression,and 27.94%in peak CPU ***,the proposed QAE-u8 model is more suitable for deployment on resource-constrained IoT edge devices.

关键词： IoT constrained system

Reliability of a Multicomponent stress-strength Model based on a bivariate Kumaraswamy Distribution with Censored Data

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Acta Mathematicae Applicatae sinica 2024年第2期40卷 478-507页

作者： Cong-hua cheng school of Mathematics and statistics Zhaoqing UniversityZhaoqing 526061China

In this paper,we consider a system which has k statistically independent and identically distributed strength components and each component is constructed by a pair of statistically dependent elements with doubly type-II censored *** elements(X1,Y1),(X2,Y2),…,(Xk,Yk)follow a bivariate Kumaraswamy distribution and each element is exposed to a common random stress T which follows a Kumaraswamy *** system is regarded as operating only if at least s out of k(1≤s≤k)strength variables exceed the random *** multicomponent reliability of the system is given by Rs,k=P(at least s of the(Z1,…,Zk)exceed T)where Zi=min(Xi,Yi),i=1,…,*** bayes estimates of Rs,k have been developed by using the Markov Chain Monte Carlo methods due to the lack of explicit *** uniformly minimum variance unbiased and exact bayes estimates of Rs,k are obtained analytically when the common second shape parameter is *** asymptotic confidence interval and the highest probability density credible interval are constructed for Rs,*** reliability estimators are compared by using the estimated risks through Monte Carlo simulations.

关键词： stress-strength model bivariate Kumaraswamy distribution multicomponent reliability doubly Type-II censored scheme interval estimation

Fuzzy Reliability and Availability of system under a Calendar-based Inspection Involving Multiple Failures and Its Application to Wind Turbine system

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Journal of systems science and systems Engineering 2024年第2期33卷 187-206页

作者： Mintu Kumar Himani Pant s.b.singh Department of Mathematics statistics and Computer science G.B.Pant University of AgricultureTechnologyPantnagarUttarakhandIndia

Uncertainty is an important factor that needs to be considered while analyzing the performance of any engineering *** order to quantify uncertainty,fuzzy set theory is frequently used by most of researchers,including energy system *** to the classical reliability theory,component lifetimes have crisp parameters,but due to uncertainty and inaccuracy in data,it is sometimes very difficult to determine the exact values of these parameters in real-world *** overcome this difficulty in the current research,failure and repair rates were taken as triangular fuzzy numbers to determine the fuzzy availability of a system undergoing calendar-based periodic inspection subject to multiple failure modes(FMs).It was assumed that each component in the system had an exponential failure rate and repair rate with fuzzy *** FMs were explicitly taken into account when a functional state of the system was *** FM had a random failure *** the occurrence of any failure,a random time was selected for the relevant corrective repair *** proposed research was studied for one of the major sources of green energy,namely a wind turbine system wherein all the derived propositions have been implemented on it.

关键词： Fuzzy reliability fuzzy availability wind turbine system multiple failure modes triangular fuzzy number

blindness-free beam scanning antenna with array of array architecture: principle,design,and experiment

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science China(Information sciences) 2024年第3期67卷 209-224页

作者： Jianxu sUN Yujian cheng school of Electronic science and Engineering University of Electronic science and Technology of China

This paper presents a 66–76-GHz sparsely-excited phased array antenna with the array of array(Ao A) architecture for eliminating the blindness and suppressing the grating lobe when scanning. For the array antennas printed on the thick dielectric layers with high relative permittivity, scanning blindness appears and seriously impacts the radiation performance. To address this issue, the Ao A topology is developed first. It finds that the scanning blindness appears due to the coupling of the radiating Floquet modes to the non-radiating surface wave(sW) modes. Therefore, the array is divided into two types of domino *** inner-phase distributions are introduced into the domino subarrays to break the one-to-one relationship between the Floquet mode and the sW mode. Then, the blindness inside ±60° scanning volume is eliminated by the aperiodic subarrays. Meanwhile, the aperiodic inner-phase distributions enhance the aperiodicity of the array and contribute to suppressing the grating lobe when scanning. Next, the meta-surface-based dipole with the shorted post is chosen as the unit cell for the proposed aperiodic array. based on these methods,the array achieves the wide-scanning performance of ±60° in the E-plane and ±30° in the H-plane, without the blindness and the grating lobe. Finally, the 16×16 array is built and simulated with the dimension of32 mm × 32 mm. At the highest operating frequency, the simulated gains are 28.42, 25.17, and 24.01 d bi when scanning to the broadside, 50° in the E-plane, and 30° in the H-plane, respectively. Compared to the ideal gain, it shows that the simulated radiation efficiency is about 84.13%, 62.08%, and 35.23% when scanning to the broadside, 50° in the E-plane, and 30° in the H-plane, respectively. The worst transmission coefficient, i.e., the worst isolation, is-11.97 d b between the central element and its two adjacent elements in the E-plane. The array prototypes are fabricated, and the experiments are carried out to ver

关键词： 6G communication systems phased array AoA aperiodic subarray wideband wide-scanning surface-wave scanning blindness grating lobe

study of hybrid nanofluid flow in a stationary cone-disk system with temperature-dependent fluid properties

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Applied Mathematics and Mechanics(English Edition) 2024年第4期45卷 677-694页

作者： A.s.JOHN b.MAHANTHEsH G.LORENZINI Center for Mathematical Needs Department of MathematicsCHRIST(Deemed to be University)Karnataka 560029India school of Mathematical and statistical sciences The University of Texas Rio Grande ValleyTexas 78539U.S.A. Department of Engineering and Architecture University of ParmaParma 43124Italy

Cone-disk systems find frequent use such as conical diffusers,medical devices,various rheometric,and viscosimetry *** this study,we investigate the three-dimensional flow of a water-based Ag-Mg O hybrid nanofluid in a static cone-disk system while considering temperature-dependent fluid *** the variable fluid properties affect the dynamics and heat transfer features is studied by Reynolds's linearized model for variable viscosity and Chiam's model for variable thermal *** single-phase nanofluid model is utilized to describe convective heat transfer in hybrid nanofluids,incorporating the experimental *** model is developed as a coupled system of convective-diffusion equations,encompassing the conservation of momentum and the conservation of thermal energy,in conjunction with an incompressibility condition.A self-similar model is developed by the Lie-group scaling transformations,and the subsequent self-similar equations are then solved *** influence of variable fluid parameters on both swirling and non-swirling flow cases is ***,the Nusselt number for the disk surface is *** is found that an increase in the temperature-dependent viscosity parameter enhances heat transfer characteristics in the static cone-disk system,while the thermal conductivity parameter has the opposite effect.

关键词： hybrid nanofluid cone-disk system laminar flow variable fluid property Nusselt number

Equalizer Zero-Determinant strategy in Discounted Repeated stackelberg Asymmetric Game

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Journal of systems science & Complexity 2024年第1期37卷 184-203页

作者： cheng Zhaoyang CHEN Guanpu HONG Yiguang Key Laboratory of systems and Control Academy of Mathematics and Systems ScienceChinese Academy of SciencesBeijing 100190China school of Mathematical sciences University of Chinese Academy of SciencesBeijing 100049China school of Electrical Engineering and Computer science KTH Royal Institute of Technology10044 StockholmSweden. Department of Control science and Engineering Tongji UniversityShanghai 201804China shanghai Research Institute for Intelligent Autonomous systems Tongji UniversityShanghai 210201China

This paper focuses on the performance of equalizer zero-determinant(ZD)strategies in discounted repeated stackelberg asymmetric *** the leader-follower adversarial scenario,the strong stackelberg equilibrium(ssE)deriving from the opponents’best response(bR),is technically the optimal strategy for the ***,computing an ssE strategy may be difficult since it needs to solve a mixed-integer program and has exponential complexity in the number of *** this end,the authors propose an equalizer ZD strategy,which can unilaterally restrict the opponent’s expected *** authors first study the existence of an equalizer ZD strategy with one-to-one situations,and analyze an upper bound of its performance with the baseline ssE *** the authors turn to multi-player models,where there exists one player adopting an equalizer ZD *** authors give bounds of the weighted sum of opponents’s utilities,and compare it with the ssE ***,the authors give simulations on unmanned aerial vehicles(UAVs)and the moving target defense(MTD)to verify the effectiveness of the proposed approach.

关键词： Discounted repeated stackelberg asymmetric game equalizer zero-determinant strategy strong stackelberg equilibrium strategy