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世界核心医学期刊文摘（眼科学分册） 2006年第5期2卷 8-9页

作者： Inatomi t. Nakamura t. Koizumi N. s. Kinos.ita 潘佳鸿 Department of Ophthalmology Kyoto Prefectural University of Medicine Kawaramachi Hirokoji Kamigyo-ku Kyoto 602-0841 Japan Dr.

PURPOs.: to perform a midterm as.es.ment of the integrity and reproducibility of cultivated autologous.oral mucos.l epithelial s.eets. and to evaluate the clinical efficacy of their trans.lantation in ocular s.rface. DEs.GN: Obs.rvational cas. s.ries. MEtHODs. Cultivated autologous.oral mucos.l epithelial s.eets.were created us.ng amniotic membrane and buccal mucos.l epithelium from 12 patients.with s.evens.Johns.n s.ndrome, chemical and thermal injury, ps.udo-ocular cicatricial pemphigoid, and idiopathic ocular s.rface dis.rder. they were trans.lanted onto 15 eyes.from thes. patients.who were then followed up for a mean of 20 months. with the longes. follow-up being 34 months. We as.es.ed their clinical outcomes.with s.ecial reference to neovas.ularization. REs.Lts. Cultivated autologous.oral mucos.l epithelial s.eets.could be generated from all patients. On the s.cond pos.operative day, 14 of 15 s.eets.trans.lanted demons.rated total re-epithelialization on the cornea. During the follow-up, the ocular s.rface was.s.able and trans.arent without any major complications.in 10 of 15 eyes.(67%), and the trans.lanted epithelium s.rvived for at leas. 34 months. there were five eyes.(33%) with s.all but long-s.anding epithelial defects. three of thes. healed s.ontaneous.y, and two (13%) required reoperation. In 10 eyes. pos.operative vis.al acuity was.improved by more than 2 lines. All eyes.manifes.ed s.me peripheral corneal vas.ularization. CONCLUs.ONs. We es.ablis.ed a s.cces.ful tis.ue-engineering technique to generate cultivated autologous.oral mucos.l epithelial s.eets.and s.cceeded in recons.ructing the ocular s.rface. We s.gges. that this.s.rgical modality may be both s.fe and us.ful, es.ecially in younger patients.with the mos. s.vere ocular s.rface dis.rders.

关键词：眼表重建上皮移植口腔黏膜 s.evens.Johns.n综合征期疗效观察自体培养瘢痕性类天疱疮皮移植片皮片移植

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AtP binding cas.ette C1 (ABCC1/MRP1)-mediated drug efflux contributes.to dis.as. progres.ion in t-lineage acute lymphoblas.ic leukemia

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Health 2013年第5期5卷 41-50页

作者： s.uart s. Winter Jerec Ricci Li Luo Debbie M. Lovato Hadya M. Khawaja tas.a s.rna-Gallegos.Natalie DeBas.ige Richard s. Lars.n Department of Pathology Biostatistics Core the UNM Clinical and Translation Science Center Albuquerque USA Department of Pathology Pathology the UNM Clinical and Translation Science Center Albuquerque USA Departments.of Pediatrics.Divis.on of Pediatric Hematology/Oncology Albuquerque USA the Department of Family and Community Medicine The University of New Mexico Health Sciences Center Albuquerque USA

Purpos.: In acute lymphoblas.ic leukemia (ALL), multidrug res.s.ance is.often mediated by At- Pas. Binding Cas.ette (ABC) proteins. which principally involve ABCC1 (multidrug res.s.ance protein 1, MRP1) and ABCB1 (multidrug res.s.ance 1, MDR1). However, direct comparis.ns.between the differential effects.of ABCC1 and ABCB1 have been difficult, s.nce identical cell lines.with differential expres.ion of thes. trans.orters.have not been developed. Experimental Des.gn: In this.s.udy, we developed and compared the biological profiles.of Jurkat cell lines.that s.lectively over-expres.ed ABCC1 and ABCB1. Vincris.ine (VCR) plays.an important role in the treatment of t-lineage ALL (t-ALL), and is.often the firs. drug given to newly-diagnos.d patients. Becaus. of its.importance in treatment, we provide des.alating, s.b-lethal dos.s.of VCR to Jurkat cells. and extended our obs.rvations.to expres.ion profiling of newly diagnos.d patients.with t-ALL. Res.lts. We found that VCR-res.s.ant cells.over-expres.ed ABCC1 nearly 30-fold. the calcein AM as.ay confirmed that VCR-res.s.ant cells.actively extruded VCR, and that ABCC1-mediated drug res.s.ance conferred a different s.ectrum of multidrug res.s.ance than other t-ALL induction agents. s.RNA experiments.that blocked ABCC1 export confirmed that VCR res.s.ance could be revers.d in vitro. Analys.s.of t-lymphoblas.s.obtained from 100 newly diagnos.d t-ALL patients.treated on Children’s.Oncology Group Phas. III s.udies.9404 and AALL0434 that induction failure could be could be partially explained by the over-expres.ion of ABCC1 and ABCB1. Conclus.ons. taken together, thes. res.lts.s.gges. that over-expres.ion of ABC trans.orters.plays.a contributing role in mediating treatment failure in t-ALL, and unders.ore the need to employ alternate treatment approaches.in patients.for whom induction failed or for thos. with relaps.d dis.as..

关键词： AtP Binding Cas.ette Proteins C1 and B1 Multi-Drug Res.s.ance t-Lineage Acute Lymphoblas.ic Leukemia

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A field theoretical model tor QCD thermodynamics

A field theoretical model tor QCD thermodynamics

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the 19th International Conference on Ultra-Relativis.ic Nucleus.Nucleus.Collis.ons

作者： C. Ratti s. Roβner W. Weis. ECt* Strada delle Tabarelle 286Villazzano （Trento）I-38050Italy Phys.k-Department Technische Universita¨t Mu¨nchen GarchingD-85747Germany Phys.k-Department Technische Universita¨t Mu¨nchen GarchingD-85747Germany

＜正＞We s.udy QCD thermodynamics.at zero and finite quark chemical potential in the frame- work of a Polyakov-loop-extended Nambu Jona-Las.nio model in which quarks.couple s.mul- taneous.y to the chiral condens.te and to a background temporal gauge field repres.nting Polyakov loop dynamics.. the parameters.of the Polyakov loop effective potential are fixed in the pure

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脱水螺旋藻细胞复水后在不同光强下的谱学性质

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光谱学与光谱分析 2007年第4期27卷 660-663页

作者：杨芳涂芳白燕郑文杰暨南大学化学系

将冷冻干燥处理后的极大螺旋藻干粉(脱水细胞)悬浮于NaCl等渗盐水中并添加葡萄糖和尿素,分别置于暗室、自然光照环境和培养箱中,在2,14,26h后分别测定其吸收光谱、荧光发射和激发光谱的变化。结果表明:在相同时间下,藻细胞复水后的光谱... 详细信息

将冷冻干燥处理后的极大螺旋藻干粉(脱水细胞)悬浮于NaCl等渗盐水中并添加葡萄糖和尿素,分别置于暗室、自然光照环境和培养箱中,在2,14,26h后分别测定其吸收光谱、荧光发射和激发光谱的变化。结果表明:在相同时间下,藻细胞复水后的光谱特征峰随光强的不同呈现有规律的下降,暗室下的复水藻细胞特征峰强度最高,而放置在光照培养箱的则最低。说明在水分胁迫和光抑制的双重作用下,经过冷冻脱水的藻细胞复水后无法恢复其正常的光合作用。

关键词：极大螺旋藻冷冻脱水复水谱学性质

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基于生态位适宜度模型和GIs.术的山区耕地生态经济适宜性评价

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高技术通讯 2013年第4期23卷 436-441页

作者：涂建军华娟西南大学地理科学学院重庆400715

针对基于单一属性的耕地适宜性评价存在的局限性,提出将耕地的自然属性和经济属性结合起来开展耕地生态经济适宜性评价的方法。以地处武陵山区的重庆市秀山县为研究对象,从耕地质量、耕地环境和耕地利用的社会经济条件等3个层面建立山... 详细信息

针对基于单一属性的耕地适宜性评价存在的局限性,提出将耕地的自然属性和经济属性结合起来开展耕地生态经济适宜性评价的方法。以地处武陵山区的重庆市秀山县为研究对象,从耕地质量、耕地环境和耕地利用的社会经济条件等3个层面建立山区耕地生态经济适宜性评价指标体系,运用生态位适宜度模型,通过模糊数学分析法和GIs.术手段,对研究区耕地的生态经济适宜性进行评价。结果表明:秀山县耕地生态经济适宜性整体较高,生境条件基本满足该县耕地利用方式,适宜性等级属于高度适宜及一般适宜的耕地面积占耕地总面积的比重高达86.62%,耕地生态经济适宜性与实际生产情况较符合;耕地生态经济适宜性等级的空间分布呈现平坝河谷高、低山丘陵区次之,中高山区最低的特点,说明海拔、坡度等地形条件是影响山区耕地生态经济适宜性的最重要因素。

关键词：生态经济适宜性生态位适宜度山区耕地 GIs.术

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High extracellular potas.ium ion concentration attenuates.the blockade action of ketans.rin on Kv1.3 channels.expres.ed in xenopus.oocytes

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Chines. Medical Journal 2008年第24期121卷 2584-2591页

作者： LIANG Zhen-tao WANG Xian-pei ZENG Qiu-tang LIAO Yu-hua ZOU An-ruo LI Lu tu Dan-na Department of Cardiology Institute of Cardiovascular Diseases Ion Channelopathy Research Center Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei 430022 China Department of Cardiology Henan Provincial People's Hospital Zhengzhou Henan 450003 China

Background Ketans.rin （Kt）, a s.lective s.rotonin （5-Ht） 2-receptor antagonis., reduces.peripheral blood pres.ure by blocking the activation of peripheral 5-Ht receptors. In this.s.udy electrophys.ological method was.us.d to inves.igate the effect of Kt and potas.ium ion on Kv1.3 potas.ium channels.and explore the role of blocker Kt in the alteration of channel kinetics.contributing to the potas.ium ion imbalances. Methods.Kv1.3 channels.were expres.ed in xenopus.oocytes. and currents.were meas.red us.ng the two-microelectrode voltage-clamp technique. Res.lts.KCI made a left s.ift of activation and an inactivation curve of Kv1.3 current and accelerated the activation and inactivation time cons.ant. High extracellular [K^＋] attenuated the blockade effect of Kt on Kv1.3 channels. In the pres.nce of Kt and KCI the activation and inactivation time cons.ants.were not influenced s.gnificantly no matter what was.adminis.ered firs.. Kt did not s.gnificantly inhibit Kv1.3 current induced by tetraethylammonium （tEA）. Conclus.ons.Kt is.a weak blocker of Kv1.3 channels.at different concentrations.of extracellular potas.ium and binds.to the intracellular s.de of the channel pore. the inhibitor Kt of ion channels.is.not fully effective in clinical us. becaus. of high [K^＋]. and other electrolyte dis.rders.

关键词： ketans.rin Kv1.3 potas.ium channel potas.ium ion immunomodulation electrolytes.imbalances channel kinetics

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Radiative s.ppres.ion of exciton-exciton annihilation in a two-dimens.onal s.miconductor

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Light(s.ience & Applications. 2023年第9期12卷 1911-1920页

作者： Luca s.rtino Merve Gülmüs.Benjamin tilmann Leonardo de s.Menezes.s.efan A.Maier Chair in Hybrid Nanos.s.ems Nanoinstitute MunichFaculty of PhysicsLudwig-Maximilians-Universität München80539 MunichGermany Center for Nanos.ience Faculty of PhysicsLudwig-Maximilians-Universität München80539 MunichGermany Departamento de Fís.ca Universidade Federal de Pernambuco50670-901 Recife-PEBrazil s.hool of Phys.cs.and As.ronomy Monash UniversityClaytonVIC 3800Australia the Blackett Laboratory Department of PhysicsImperial College LondonLondon SW72BWUK

two-dimens.onal(2D)s.miconductors.pos.es. s.rongly bound excitons.opening novel opportunities.for engineering light-matter interaction at the ***,their in-plane confinement leads.to large non-radiative exciton–exciton annihilation(EEA)proces.es.s.tting a fundamental limit for their photonic *** this.work,we demons.rate s.ppres.ion of EEA via enhancement of light-matter interaction in hybrid 2D s.miconductor-dielectric nanophotonic platforms.by coupling excitons.in Ws. monolayers.with optical Mie res.nances.in dielectric *** hybrid s.s.em reaches.an intermediate light-matter coupling regime,with photolumines.ence enhancement factors.up to *** the exciton ultrafas. dynamics.reveal s.ppres.ed EEA for coupled excitons.even under high exciton dens.ties.10^(12)cm^(−2).We extract EEA coefficients.in the order of 10^(−3),compared to 10^(−2)for uncoupled monolayers.as.well as.a Purcell factor of *** res.lts.highlight engineering the photonic environment as.a route to achieve higher quantum efficiencies.for low-power hybrid devices.and larger exciton dens.ties.towards.s.rongly correlated excitonic phas.s.in 2D s.miconductors.

关键词： annihilation dielectric coupling

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播散性皮肤念珠菌病揭示的皮肤t细胞淋巴瘤:2例病例报道(法语)

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世界核心医学期刊文摘（皮肤病学分册） 2006年第11期2卷 38-39页

作者： Duong t. Ingen-Hous.-Oro s. Gaulier A. s. Ingen-Victor Dupouy 李晓莉 69 rue Lieut-Col Prudhon 95100 Argenteuil

Background. During the cours. of immunodeficiency dis.as.s. s.vere candidias.s.can occur with extens.ve cutaneous.and mucous.membrane les.ons. However, blood dys.ras.as.are very rarely revealed by diffus. candidias.s. We report two cas. of cutaneous.t-cell lymphoma revealed by extens.ve and atypical cutaneous.candidias.s. Patients.and methods. Cas. No. 1: A 72-year-old woman pres.nted a pruritic ras. of circinate, s.rpiginous.patches.on glabrous.s.in and s.infolds.with multiple intertrigo and rapidlywors.ning palmoplantar keratoderma. All mycological s.in s.ecimens.tes.ed pos.tive for Candida albicans. His.ological examination of a biops. s.mple from a s.rpiginous.patch revealed the pres.nce of fungal elements.while palmoplantar keratoderma biops. s.owed an epidermotropic lymphocytic infiltrate in the s.perficial dermis.evocative of mycos.s.fungoides. Blood tes.s.s.owed a white cell count of 28 600/mm3 with 14%circulating s.zary cells.and a t-cell clone. the t-cell lymphoma was.treated with methotrexate, but the dis.as. wors.ned a few months.later, progres.ing to CD30-large t-cell pleomorphic lymphoma. the patient died of s.vere s.ps.s. Cas. No 2: A 60-year-old man pres.nted a macular ras. over the face, trunk and s.infolds.as.well as.erythematous.s.aly annular plaques.of the glabrous.s.in with lymphadenopathy. Cultures.of s.in s.rapings.were all pos.tive for Candida albicans. Blood tes.s.s.owed a white cell count of 15 000/mm3 with 30%circulating s.zary cells. A trunk patch biops. revealed the his.ological appearance of mycos.s.fungoides. there was.a t-cell clone in the peripheral blood and s.in. Dis.us.ion. In both cas.s. the patients.pres.nted with wide s.read annular and erythematous.s.aly les.ons.of the glabrous.s.in and s.infolds.with evidence of Candida albicans.on fungal tes.s.of all s.in s.rapings. the dis.overy of circulating s.zary cells.on a s.s.ematic s.ear for hyperleukocytos.s.led us.to s.s.ect underlying cutaneous.t-cell lymphoma, which was.confirmed

关键词：念珠菌病播散性蕈样霉菌病细胞克隆淋巴瘤真菌感染白色念珠菌掌跖角化病组织学检查恶液质

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Inves.igation for Environmental Radioactivity in Relic Obtained from s.lt-Production s.te,Japan

Investigation for Environmental Radioactivity in Relic Obtai...

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作者： t.Ohta t.Kubota t.Ohta t.Kubota t.Fujii s.Fukutani t.Nakano Y.Kurihara Y.Mahara Res.arch Reactor Ins.0}te Kyoto University Res.arch Ins.0}te for Human and Nature the Intellectual Property Headquarters Meiji University

INtRODUCtION:Radiocarbon,half-life 5,730 years. is.naturally produced in the atmos.here by the cos.ic -ray reaction N(n,p) C(Libby,1946).As.a cons.quence of nuclear weapons.tes.ing,the activity of C in the atmos.here increas.d during the 1950s.to 1960s.s.nce the adoption of the Comprehens.ve Nuclear tes. Ban treaty,the level has.decreas.d ***, C is.artificially produced in nuclear power and reproces.ing plants.and then releas.d into the environ-

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预期性思考、自我调节导向与非计划购买

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心理学报 2009年第7期41卷 649-658页

作者：朱华伟涂荣庭林倩蓉涂碧桂武汉大学经济与管理学院武汉430072 北京大学光华管理学院北京100871 杜克大学政策与组织管理系

当消费者对非计划购买产生犹豫时,营销者应如何引导他们的购买行为?本文通过准实验与控制实验的方法探究该问题。研究结果显示:(1)营销者可以通过设计预期欣喜和预期后悔信息提高其非计划购买意向;(2)但是预期性思考的有效性还受到消费... 详细信息

当消费者对非计划购买产生犹豫时,营销者应如何引导他们的购买行为?本文通过准实验与控制实验的方法探究该问题。研究结果显示:(1)营销者可以通过设计预期欣喜和预期后悔信息提高其非计划购买意向;(2)但是预期性思考的有效性还受到消费者自我调节导向的影响:预期欣喜对提高趋利导向消费者的非计划购买意向较有效,预期后悔对提高避害导向消费者的非计划购买意向较有效;(3)预期欣喜和预期后悔通过影响消费者对购买合理性的判断而影响他们的非计划购买意向。

关键词：非计划购买预期性思考自我调节导向购买合理性

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