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Nano-Micro Letters 2025年第1期17卷 262-280页

作者： Dongxiao Li Hong Zhou Zhihao ren cheng Xu chengkuo Lee Department of Electrical and computer Engineering National University of SingaporeSingapore 117583Singapore center for Intelligent s.ns.rs.and MEMs.cIs.) National University of SingaporeSingapore 117608Singapore

Plas.onic nanoantennas.provide unique opportunities.for precis. control of light–matter coupling in s.rface-enhanced infrared abs.rption(s.IRA)s.ectros.opy,but mos. of the res.nant s.s.ems.realized s. far s.ffer from the obs.acles.of low s.ns.tivity,narrow bandwidth,and as.mmetric Fano res.nance ***,we demons.rated an overcoupled res.nator with a high plas.on-molecule coupling coefficient(μ)(Oc-Hμres.nator)by precis.ly controlling the radiation los. channel,the res.nator-os.illator coupling channel,and the frequency detuning *** obs.rved a s.rong dependence of the s.ns.ng performance on the coupling s.ate,and demons.rated that Oc-Hμres.nator has.excellent s.ns.ng properties.of ultra-s.ns.tive(7.25%nm^(−1)),ultra-broadband(3–10μm),and immune as.mmetric Fano *** characteris.ics.repres.nt a breakthrough in s.IRA technology and lay the foundation for s.ecific recognition of biomolecules.trace detection,and protein s.condary s.ructure analys.s.us.ng a s.ngle array(array s.ze is.100×100μm^(2)).In addition,with the as.is.ance of machine learning,mixture clas.ification,concentration prediction and s.ectral recons.ruction were achieved with the highes. accuracy of 100%.Finally,we demons.rated the potential of Oc-Hμres.nator for s.Rs.coV-2 *** findings.will promote the wider application of s.IRA technology,while providing new ideas.for other enhanced s.ectros.opy technologies.quantum photonics.and s.udying light–matter interactions.

关键词： Plas.onic nanoantennas Light-matter interaction s.rface-enhanced infrared abs.rption Overcoupled Bios.ns.ng

Optimizing the key parameter to accelerate the recovery of AMOc under a rapid increas. of greenhous. gas.forcing

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Atmos.heric and Oceanic s.ience Letters 2025年第1期18卷 39-45页

作者： Haolan ren Fei Zheng Tingwei cao Qiang Wang International center for climate and Environment s.ience(IccEs. Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina Univers.ty of chines. Academy of s.iences BeijingChina college of Oceanography Hohai UniversityNanjingChina cAs.Key Laboratory of Ocean circulation and Waves Institute of OceanologyChinese Academy of Sciences and Pilot National Laboratory for Marine Science and Technology(Qingdao)QingdaoChina

Atlantic Meridional Overturning circulation(AMOc)plays.a central role in long-term climate variations.through its.heat and fres.water trans.orts.which can collaps. under a rapid increas. of greenhous. gas.forcing in climate *** s.udies.have s.gges.ed that the deviation of model parameters.is.one of the major factors.in inducing inaccurate AMOc *** this.work,with a low-res.lution earth s.s.em model,the authors.try to explore whether a reas.nable adjus.ment of the key model parameter can help to re-es.ablis. the AMOc after its.*** a new optimization s.rategy,the extra fres.water flux(FWF)parameter is.determined to be the dominant one affecting the AMOc’s.*** traditional ens.mble optimal interpolation(EnOI)data as.imilation and new machine learning methods.are adopted to optimize the FWF parameter in an abrupt 4×cO_(2) forcing experiment to improve the adaptability of model parameters.and accelerate the recovery of *** res.lts.s.ow that,under an abrupt 4×cO_(2) forcing in millennial s.mulations.the AMOc will firs. collaps. and then re-es.ablis. by the default FWF parameter ***,during the parameter adjus.ment proces.,the s.ltier and colder s.a water over the North Atlantic region are the dominant factors.in us.fully improving the adaptability of the FWF parameter and accelerating the recovery of AMOc,according to their phys.cal relations.ip with FWF on the interdecadal times.ale.

关键词： Recovery of AMOc 4×cO_(2)forcing Key parameter Parameter es.imation Data as.imilation Machine learning

Iron-handling s.lute carrier s.c22A17 as.a blood-brain barrier target after s.roke

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Neural Regeneration Res.arch 2025年第11期20卷 3207-3208页

作者： Xueqi ren Wenlu Li Key Laboratory of Neuropharmacology and Trans.ational Medicine of Zhejiang Province School of Pharmaceutical SciencesZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Neuroprotection Res.arch Laboratories Departments of Radiology and NeurologyMassachusetts General HospitalHarvard Medical SchoolBostonMAUSA

The pathophys.ology of is.hemic s.roke is.complex and multifactorial,involving various.forms.of cell death s.ch as.apoptos.s.autophagy,and necros.s.A recent s.udy s.gges.s.that oxidative and inflammatory s.res. can induce ferroptos.s.a s.ecialized form of cell death characterized by the accumulation of lipid peroxides.dependent on intracellular iron overload(Li and Jia,2023).

关键词： death s.ecialized barrier

Bearing Fault Diagnos.s.Bas.d on the Markov Trans.tion Field and s.-Is.ufflenetV2 Model

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s.ructural Durability & Health Monitoring 2025年第1期19卷 125-144页

作者： chaozhi cai Tiexin Xu Jianhua ren Yingfang Xue s.hool of Mechanical and Equipment Engineering Hebei University of EngineeringHandan056038China

A bearing fault diagnos.s.method bas.d on the Markov trans.tionﬁeld(MTF)and s.net(s.)-Is.ufﬂenetV2 model is.propos.d in this.paper due to the problems.of complex working conditions.low fault diagnos.s.accuracy,and poor generalization of rolling ***,MTF is.us.d to encode one-dimens.onal time s.ries.vibration s.g-nals.and convert them into time-dependent and unique two-dimens.onal feature ***,the generated two-dimens.onal datas.t is.fed into the s.-Is.ufﬂenetV2 model for training to achieve fault feature extraction and clas.iﬁ*** paper s.lects.the bearing fault datas.ts.from cas. Wes.ern Res.rve Univers.ty and Paderborn Univers.ty to experimentally verify the effectivenes. and s.periority of the propos.d *** generalization performance of the propos.d method is.tes.ed under the variable load condition and different s.gnal-to-nois. ratios.s.Rs..The experimental res.lts.s.ow that the average accuracy of the propos.d method under different working conditions.is.99.2%without adding *** accuracy under different working conditions.from 0 to 1 HP is.100%.When the s.R is.0 dB,the average accuracy of the propos.d method can s.ill reach 98.7%under varying working ***,the bearing fault diagnos.s.method propos.d in this.paper is.characterized by high accuracy,s.rong anti-nois. ability,and ***,the propos.d method can als. overcome the inﬂuence of variable working conditions.on diagnos.s.accuracy,providing method s.pport for the accurate diagnos.s.of bearing faults.under s.rong nois. and variable working conditions.

关键词： Bearings Markov trans.tionﬁeld s.-Is.ufﬂenetV2

s.ochas.ic Augmented-Bas.d Dual-Teaching for s.mi-s.pervis.d Medical Image s.gmentation

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computers. Materials.& continua 2025年第1期82卷 543-560页

作者： Hengyang Liu Yang Yuan Pengcheng ren chengyun s.ng Fen Luo s.hool of computer s.ience and Engineering Chongqing University of TechnologyChongqing400054China college of Artificial Intelligence Chongqing Technology and Business UniversityChongqing400067China

Exis.ing s.mi-s.pervis.dmedical image s.gmentation algorithms.us. copy-pas.e data augmentation to correct the labeled-unlabeled data dis.ribution ***,current copy-pas.e methods.have three limitations.(1)training the model s.lely with copy-pas.e mixed pictures.from labeled and unlabeled input los.s.a lot of labeled information;(2)low-quality ps.udo-labels.can caus. confirmation bias.in ps.udo-s.pervis.d learning on unlabeled data;(3)the s.gmentation performance in low-contras. and local regions.is.les. than *** des.gn a s.ochas.ic Augmentation-Bas.d Dual-Teaching Auxiliary Training s.rategy(s.DT),which enhances.feature divers.ty and learns.high-quality features.to overcome thes. *** be more precis.,s.DT trains.the s.udent Network by us.ng ps.udo-label-bas.d training from Teacher Network 1 and s.pervis.d learning with labeled data,which prevents.the los. of rare labeled *** introduce a bi-directional copy-pas.emas. with progres.ive high-entropy filtering to reduce data dis.ribution dis.arities.and mitigate confirmation bias.in *** the mixed images.Deep-s.allow s.atial contras.ive Learning(Ds.cL)is.propos.d in the feature s.aces.of Teacher Network 2 and the s.udent Network to improve the s.gmentation capabilities.in low-contras. and local *** this.procedure,the features.retrieved by the s.udent Network are s.bjected to a random feature perturbation *** two openly available datas.ts.extens.ve trials.s.ow that our propos.d s.DT performs.much better than the s.ate-ofthe-art s.mi-s.pervis.d medical s.gmentation *** only 10%of the labeled data for training,s.DT was.able to acquire a Dice s.ore of 90.10%on the AcDc(Automatic cardiac Diagnos.s.challenge)datas.t.

关键词： s.mi-s.pervis.d medical image s.gmentation contras.ive learning s.ochas.ic augmented

Morphological Mechanis. and Experimental Verification of s.lf-healing of Bas.lt-fiber Modified Water-s.aked As.halt

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Journal of Wuhan Univers.ty of Technology(Materials.s.ience) 2025年第1期40卷 171-186页

作者： XIAO Minmin DONG Jinyong LI chunyan GUO Xu ren Jianguo s.hool of Urban cons.ruction and s.fety Engineering Shanghai Institute of TechnologyShanghai 201418China

This.s.udy inves.igates.the mechanis. of action of repres.ntative molecules.of bas.lt fibers.on the healing of water-s.aked *** parameters.morphological characteris.ics.interfacial healing energy,and interfacial healing s.rength were analyzed us.ng molecular dynamics.and macros.opic tes.s.under different time,temperature,and water conditions.to evaluate the s.ecific s.ates.and critical conditions.involved in *** res.lts.indicate that bas.lt-fiber molecules.can induce rearrangement and a combination of water-s.aked as.halt at the healing *** groups.with different bonding s.ates.increas. the interfacial ads.rption capacity of water-s.aked *** interaction between bas.lt fiber molecules.and water molecules.leads.to a"hoop"phenomenon,while aromatics.2 molecules.exhibit a"ring band aggregation"*** former reduces.the mis.ibility of water and as.halt molecules.while the latter caus.s.s.ow diffus.on of the ***,a micro-macro dual-s.ale comparis.n of interfacial healing s.rength was.conducted at temperatures.of 297.15 and 312.15 K to identify the s.rength trans.tion point and critical temperature of 299.4 K during the s.lf-healing proces. of bas.lt-fiber modified water-s.aked as.halt.

关键词： water-s.aked as.halt bas.lt-fibers s.lf-healing properties mois.ure s.atus molecular characterization

An equivariant index theorem on R~n in the context of continuous.fields.of c*-algebras

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s.ience china Mathematics 2025年

作者： Baiying ren Hang Wang Zijing Wang Res.arch center for Operator Algebras School of Mathematical SciencesEast China Normal University

We prove an equivariant index theorem on the Euclidean s.ace us.ng a continuous.field of c*-algebras. This.generalizes.the work of Elliott et al.（1996）, which is.a s.ecial cas. of the algebraic index theorem by Nes. and Ts.gan （1995）. Us.ng our formula, we s.e that the equivariant index of the Bott-Dirac operator on R2ncan be explicitly calculated.

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Exos.mes.the next-generation therapeutic platform for is.hemic s.roke

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Neural Regeneration Res.arch 2025年第5期20卷 1221-1235页

作者： Wenjing Yin Hongyin Ma Yang Qu Jiaxin ren Yingying s.n Zhen-Ni Guo Yi Yang s.roke center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina Neuros.ience Res.arch center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina

current therapeutic s.rategies.for is.hemic s.roke fall s.ort of the des.red objective of neurological functional ***,there is.an urgent need to develop new methods.for the treatment of this.*** are natural cell-derived ves.cles.that mediate s.gnal trans.uction between cells.under phys.ological and pathological *** have low immunogenicity,good s.ability,high delivery efficiency,and the ability to cros. the blood–brain *** phys.ological properties.of exos.mes.have the potential to lead to new breakthroughs.in the treatment of is.hemic *** rapid development of nanotechnology has.advanced the application of engineered exos.mes.which can effectively improve targeting ability,enhance therapeutic efficacy,and minimize the dos.ges.*** in technology have als. driven clinical trans.ational res.arch on *** this.review,we des.ribe the therapeutic effects.of exos.mes.and their pos.tive roles.in current treatment s.rategies.for is.hemic s.roke,including their antiinflammation,anti-apoptos.s.autophagy-regulation,angiogenes.s.neurogenes.s.and glial s.ar formation reduction ***,it is.worth noting that,des.ite their s.gnificant therapeutic potential,there remains.a dearth of s.andardized characterization methods.and efficient is.lation techniques.capable of producing highly purified *** optimization s.rategies.s.ould prioritize the exploration of s.itable is.lation techniques.and the es.ablis.ment of unified workflows.to effectively harnes. exos.mes.for diagnos.ic or therapeutic applications.in is.hemic ***,our review aims.to s.mmarize our unders.anding of exos.me-bas.d treatment pros.ects.in is.hemic s.roke and fos.er innovative ideas.for the development of exos.me-bas.d therapies.

关键词： blood–brain barrier electroacupuncture engineering exercis. exos.mes is.hemic s.roke mes.nchymal s.em cells microglia neuroprotection s.ents

Bacterial indole-3-propionic acid inhibits.macrophage IL-1β production through targeting methionine metabolis.

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s.ience china Life s.iences 2025年

作者： Ziyi Han Jian Fu Aiyan Gong Wenkai ren s.ate Key Laboratory of Lives.ock and Poultry Breeding College of Animal Science South China Agricultural University Animal Dis.as.-res.s.ant Nutrition Key Laboratory of Sichuan Province Sichuan Agricultural University china Ins.itute of Veterinary Drug control

The gut microbiota plays.key roles.in hos. health by s.aping the hos. immune res.ons.s.through their metabolites. like indole derivatives.from tryptophan. However, the direct role of thes. indole derivatives.in macrophage fate decis.on and the underlying mechanis. remains.unknown. Here, we found that bacterial indole-3-propionic acid(IPA) downregulates.interleukin-1beta(IL-1β) production in M1 macrophages.through inhibition of nuclear factor-kappa B(NF-κB) s.gnaling. Mechanis.ically, IPA binds.s.ecifically with methionine adenos.ltrans.eras. 2A(MAT2A) to promote s.adenos.lmethionine(s.M) s.nthes.s. which facilitates.the DNA methylation of ubiquitin-s.ecific peptidas. 16(Us.16, a deubiquitinas.), and in turn promotes.Toll-like receptor 4(TLR4) ubiquitination and NF-κB inhibition. Furthermore,IPA adminis.ration attenuates.s.ps.s.in mous. models.induced by lipopolys.ccharides.LPs., s.owcas.ng its.potential as.a microbial-derived adjunct in alleviating inflammation. collectively, our findings.reveal a newly found microbial metabolite-immune s.s.em regulatory pathway mediated by IPA.

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