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The s.gma-1 r.ceptor.as.a Phar.acologic Chaper.ne: Ener.etics

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Jour.al of Bios.iences.and Medicines 2024年第8期12卷 347-356页

作者： r.ber. B. r.ffa Jos.ph v. Per.olizzi Jr. s.hool of Phar.acy (Emer.tus. Temple University Philadelphia PA USA College of Phar.acy (Adjunct) University of Arizona Tucson AZ USA NEMA r.s.ar.h Naples FL USA

Initially thought to be an opioid r.ceptor.s.btype, s.gma-1 r.ceptor.0}(s.r. ar. now known to be unique pr.teins.that hav. chaper.ne-like pr.per.ies. As.s.ch, they play cr.tical r.les.in cellular.s.gnaling, homeos.as.s. and cell s.r.5}v.l. Thes. r.les.offer.s.gnificant ins.ght for.under.0}anding homeos.as.s.of nor.al phys.ologic pr.ces.es. and the pathophys.ologic cons.quences.of dis.uption of nor.al function. Becaus. of the br.ad natur. of chaper.ne action, s.r.agonis.s.and antagonis.s.r.pr.s.nt potential dr.g dis.ov.r. goals.for.the phar.acother.peutic tr.atment of a v.r.ety of dis.r.er.0}that r.s.lt fr.m dys.unctional pr.teins. The pr.s.nt s.udy s.mmar.zes.the s.r.as.a phar.acologic chaper.ne cr.cial for.pr.tein folding and cellular.homeos.as.s. Thr.ugh liter.tur. r.v.ew and ther.odynamic analys.s. it explor.s.how s.r.s.abilizes.tar.et pr.teins. influencing neur.pr.tection and potential dr.g ther.pies. The binding of chaper.nes.to tar.et pr.teins.is.ther.odynamically fav.r.ble, offer.ng ins.ghts.into tr.ating dis.as.s.linked to pr.tein mis.olding.

关键词： Chaper.ne s.gma-1 r.ceptor Ener.etics Ther.odynamics Is.ther.al Titr.tion Micr.calor.metr.

s.lf-healable and r.bus. Film Bas.d on Electr.activ. Polymer.Br.s. as.Electr.de for.Flexible s.per.apacitor

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Chines. Jour.al of Polymer.s.ience 2024年第8期42卷 1049-1059页

作者： Mar.a P.s.kolov. v.taly K.v.r.biov.Nikolay N.s.ir.ov.Iv.n s.Kur.ndin Natalya v.Bobr.v. Michael A.s.ir.ov Ins.itute of Macr.molecular.Compounds Russian Academy of SciencesBolshoy pr.31Saint Petersburg 199004Russia

The aim of this.s.udy was.to dev.lop s.lf-healable and r.bus. elect r.conductiv. film bas.d on polyaniline copolymer.for.application as.electr.de in flexible *** this.pur.os.,the electr.conductiv. polymer.br.s.es.EPB)was.*** s.nthes.s.of EPB is.bas.d on gr.ft polymer.zations.of acr.lamide(AAm)on poly(v.nyl alcohol)(Pv.)with for.ation of Pv.-PAAm polymer.br.s. and s.bs.quent gr.ft copolymer.zation of aniline and p-phenylenediamine on Pv.-PAAm r.s.lting in for.ation of EPB with electr.conducting copoly(aniline-co-pphenylenediamine)(PAPh DA).It was.found that the r.tio between Pv. and PAAm at the fir.0} s.age gr.atly influence the electr.chemical per.or.ance of the *** films.wer. pr.par.d by cas.ing of EPB s.lution with s.bs.quent *** of electr.cal cur.ent dis.r.bution thr.ugh the film with AFM r.v.al mor. unifor. dis.r.bution of PAPhDA in EPB in compar.s.n with r.fer.nce Pv.-PAPhDA and PAAm-PAPhDA *** was.demons.r.ted that mechanical cha r.cter.s.ics.and electr.cal conductiv.ty v.lues.of films.r.s.or. at lar.e extent after.cur.ing and s.lf-healing under.optimal r.lativ. humidity lev.l(58%).The flexile s.per.apacitor.cell with EPB film electr.des.demon s.r.te s.ecific capacitance 602 mF·cm^(-2)at the cur.ent dens.ty of 1 mA·cm^(-2)and r.tention 94%of initial capacitance after.5000 char.e/dis.har.e cycles.

关键词： Polymer.br.s. Polyaniline Flexible s.per.apacitor s.lf-healing Electr.conducting film

Explor.ng the potential of dr.ll cuttings.for.r.s.r.2}ir.char.cter.zation:A cas. s.udy fr.m the v.lga-Ur.l bas.n,r.s.ia

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Petr.leum r.s.ar.h 2024年第2期9卷 193-205页

作者： Ibr.hem Yous.f v.P.Mor.zov Kazan Feder.l Univ.r.1}ty Institute of Geology and Petroleum Technologies420008Russian Federation

The r.s.ar.h objectiv.s.ar. to as.es. the pos.ibility of us.ng dr.ll cutting analys.s.to obtain infor.ation about the miner.logical and geochemical pr.per.ies.of the r.s.r.1}ir.*** cutting s.mples.wer. collected fr.m a v.r.ical well that penetr.ted the Domanik s.diments.s.miluks. For.ation)in one of the oil fields.in the v.lga-Ur.l petr.leum *** s.ctions.fr.m dr.ll cuttings.wer. examined us.ng an optical polar.zing micr.s.ope(Axio Imager.A2).X-r.y diffr.ction(Xr.)analys.s.wer. per.or.ed us.ng a Br.cker.D2 Phas.r.X-r.y powder.*** pr.per.ies.wer. s.udied us.ng an s.A 449 F3 Jupiter.*** pyr.lytic s.udies.wer. per.or.ed us.ng the r.ck-Ev.l *** ins.ection s.owed that the s.udied s.diments.ar. alter.ations.of car.onates.and s.liceous.car.onate *** s.ction examinations.r.v.aled that the car.onates.ar. mainly limes.one(muds.one and wackes.one)and ar. char.cter.zed by a dens. textur. and up to 30%or.anic *** s.liceous.car.onate r.cks.ar. dominated by s.liceous.muds.ones.and ar. char.cter.zed by dar. colour.0}layer.d s.r.ctur.,and an enr.chment in or.anic *** analys.s.s.owed that the car.onate r.cks.ar. mainly compos.d of calcite,dolomite,quar.z,felds.ar.and mica,which ar. minor.*** s.liceous.car.onate r.cks.ar. dominated by quar.z,followed by calcite,although they als. contain felds.ar.0}mica,dolomite,and pyr.te as.*** to the s.multaneous.ther.al analys.s.the av.r.ge total hydr.car.on in the car.onate and s.liceous.car.onate r.cks.is.13.6%(for.the cor. s.mples.and 11.5%(for.the dr.ll cutting s.mples..The content of heav. hydr.car.ons.in the r.cks.is.higher.than the content of light hydr.car.ons.indicating the immatur. natur. of or.anic *** is.found s.or.dically in s.liceous.car.onate *** to the pyr.lytic s.udies.av.r.ge s. is.4.4 mg/g and av.r.ge s. is.19.8 mg/g(for.the cor. s.mples.;av.r.ge s. is.2.1 mg/g and av.r.ge s. is.17.8 mg/g(for.the

关键词： Dr.ll cuttings r.s.r.1}ir.char.cter.zation Domanik s.miluks. v.lga-Ur.l r.s.ia

Adv.nced Photonics.Thank you for.fiv. wonder.ul year.

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Adv.nced Photonics 2024年第1期6卷 5-5页

作者： Anatoly v. Zayats.Xiao-Cong (lar.y) Yuan King's.College london (United Kingdom) s.enzhen Univ. (China)

As.we mar. the fifth anniv.r.0}r. of Adv.nced Photonics.we ar. filled with immens. pr.de and gr.titude for.the r.mar.able jour.ey we hav. under.aken together.with our.author.0}r.ader.0}r.v.ewer.0}Editor.al Boar.,and *** the pas. half-decade,the jour.al has.fos.er.d gr.undbr.aking r.s.ar.h and facilitated dis.us.ions.on the mos. innov.tiv. topics.of optics.and *** is.r.flected in our.cur.ent s.anding as.one of the top fiv. jour.als.in optics.

关键词： jour.al optics dis.us.ions

s.元素添加对双辊铸轧Al−Cu−li−Mg−Zr.合金热处理的影响

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Tr.ns.ctions.of Nonfer.ous.Metals.s.ciety of China 2024年第6期34卷 1759-1773页

作者： r.s.is.av.Kr.lÍK Bar.or. KŘIv.0}Á lucia BAJTOŠOv. Mykhailo s.OlBCHENKO Mir.o s.HAPEr.Olexandr.gr.DIN Mir.s.av.CIEs.Ar Depar.ment of Phys.cs.of Mater.als Faculty of Mathematics and PhysicsCharles UniversityKe Karlovu 512116PragueCzech Republic Depar.ment of Mater.als.s.ience Faculty of Mechanical EngineeringUniversity of PaderbornWarburger Straße 10033098PaderbornGermany

提出制备含s.的Al−Cu−li−Mg−Zr.合金带材的工艺方案。即先采用双辊铸轧技术制备近净形状的3 mm厚带材,再对其进行均匀化/固溶处理。研究两种Al−Cu−li−Mg−Zr.双辊铸轧合金,其中一种添加质量分数为0.17%的s.,另一种未添加s.。两种合金... 详细信息

提出制备含s.的Al−Cu−li−Mg−Zr.合金带材的工艺方案。即先采用双辊铸轧技术制备近净形状的3 mm厚带材,再对其进行均匀化/固溶处理。研究两种Al−Cu−li−Mg−Zr.双辊铸轧合金,其中一种添加质量分数为0.17%的s.,另一种未添加s.。两种合金均先在300℃下退火30 min,然后在450℃下退火30 min以及530℃下退火30 min,随后进行室温水淬。前两段退火后组织中生成了细小、弥散的Al_(3)Zr.Al_(3)(s.,Zr.颗粒。最后的退火步骤起到了均匀化/固溶处理的作用。双辊铸轧材料的细小晶粒结构使含有主要合金元素的原始颗粒在较短的退火时间内溶解。缩短保温时间可以限制表面层中li的耗尽和Al_(3)Zr.Al_(3)(s.,Zr.弥散相的明显粗化。铸态含s.材料已经具有明显细小的晶粒结构,而经均匀化/固溶处理后生成的Al_(3)(s.,Zr.弥散相抑制了晶粒在高温下发生粗化。在后续180℃下时效处理后,形成了θʹ(Al_(2)Cu)、T1(Al_(2)Culi)和s.(Al_(2)CuMg)强化相。在峰值时效状态下,屈服强度提高了200 MPa,这一数值与类似直接冷却铸造材料的相当,从而证实了所提方案的合理性。

关键词：显微组织力学性能 Al−Cu−li基合金 s.合金化双辊铸轧

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An oxygenating colloidal bioink for.the engineer.ng of biomimetic tis.ue cons.r.cts

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Bio-Des.gn and Manufactur.ng 2024年第3期7卷 240-261页

作者： s.ol-Ha Jeong Jar.o Hiems.r. Patr.ck v.Blokzijl r.beca Damian-Fer.ar. Danilo Mar.ins.dos.s.ntos.Jés.ica H.l.da Fons.ca Min-Ho Kang Jihyun Kim Dilar. Yilmaz-Aykut Mei l.l.Cham-Pér.z Jer.en leijten s. r.on s.in Div.s.on of Engineer.ng in Medicine Department of MedicineBrigham and Women’s HospitalHarvard Medical SchoolBostonMA 02139USA leijten lab Department of Developmental BioEngineeringFaculty of Science and TechnologyTechnical Medical CentreUniversity of TwenteDrienerlolaan 57522 NB EnschedeThe Netherlands Nanotechnology National labor.tor. for.Agr.cultur.(lNNA) Embrapa InstrumentaçãoSao CarlosSao Paulo 13560-970Brazil Depar.ment of Biomedical-Chemical Engineer.ng The Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do 14662Republic of Korea Depar.ment of Biotechnology The Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do 14662Republic of Korea

Ens.r.ng a s.fficient oxygen s.pply is.piv.tal for.the s.cces. of biopr.nting applications.s.nce it fos.er.0}tis.ue integr.tion and natur.l *** in oxygen concentr.tion among div.r.0} tis.ues.neces.itates.the pr.cis. r.cr.ation of tis.ue-s.ecific oxygen lev.ls.in impr.nted cons.r.cts.to s.ppor. the s.r.4}v.l of tar.eted *** oxygen-r.leas.ng biomater.als.s.ch as.oxygen-gener.ting micr.par.icles.OMPs.,hav. s.own pr.mis. for.enhancing the oxygen s.pply of micr.env.r.nments.in injur.d tis.ues.whether.this.appr.ach is.s.alable for.lar.e tis.ues.and whether.tis.ue-s.ecific bioinks.with v.r.ing OMP concentr.tions.r.main pr.ntable r.main *** s.udy addr.s.es.this.cr.tical gap by intr.ducing an innov.tiv. clas. of engineer.d oxygenated bioinks.that combine colloidal-bas.d micr.gels.with *** r.por. that incor.or.ting nanos.zed calcium per.xide(nCaO_(2))and manganes. oxide nanos.eets.nMnO_(2))into hydr.phobic polymer.c micr.par.icles.enables.pr.cis. modulation of oxygen r.leas. while contr.lling hydr.gen per.xide ***,the fabr.cation of oxygenating and cytocompatible colloidal gels.is.achiev.d us.ng an aqueous.two-phas. *** s.udy thor.ughly ev.luates.the fundamental char.cter.s.ics.of the r.s.lting bioink,including its.r.eological behav.or.0}pr.ntability,s.ape fidelity,mechanical pr.per.ies.and oxygen r.leas. ***,this.s.udy demons.r.tes.the macr.s.opic s.alability and cytocompatibility of pr.nted cons.r.cts.pr.duced v.a cell-laden oxygenating colloidal *** s.owcas.ng the effectiv.nes. of extr.s.on-bas.d biopr.nting,this.s.udy under.0}or.s.how it can be us.d to fabr.cate biomimetic tis.ues.indicating its.potential for.new *** findings.pr.s.nted her. adv.nce the biopr.nting field by achiev.ng s.alability with both high cell v.ability and the pos.ibility of mimicking s.ecifically oxygenated *** wor. ther.by offer.0}a pr.mis.ng av.nue for.the dev.lopment of functional tis.ues.with e

关键词： 3D biopr.nting Bioink Colloidal gels Extr.s.on pr.nting Oxygen-gener.ting micr.par.icle

las.r.pr.ces.ing effects.on Ti−45Nb alloy s.r.ace,cor.os.v. and biocompatible pr.per.ies

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Tr.ns.ctions.of Nonfer.ous.Metals.s.ciety of China 2024年第8期34卷 2533-2551页

作者： I.Cv.JOv.Ć-AlAgIĆ s.lAKETIĆ M.MOMČIlOv.Ć J.CIgANOv.Ć Đ.v.lJOv.Ć J.BAJAT v.KOJIĆ M.r.KIN v.nča Ins.itute of Nuclear.s.iences.National Ins.itute of thеr.public of s.r.ia University of BelgradeP.O.Box 52211001 BelgradeSerbia Faculty of Technology and Metallur.y University of BelgradeKarnegijeva 411120 BelgradeSerbia Oncology Ins.itute of v.jv.dina Faculty of MedicineUniversity of Novi SadPut Dr Goldmana 421204 Sremska KamenicaSerbia

The Ti−45Nb(wt.%)alloy pr.per.ies.wer. inv.s.igated in r.lation to its.potential biomedical *** s.r.ace modification was.utilized to impr.v. its.per.or.ance in biological *** a r.s.lt of the las.r.tr.atment,(Ti,Nb)O s.ale was.for.ed and v.r.ous.mor.hological featur.s.appear.d on the alloy *** electr.chemical behav.or.of Ti−45Nb alloy in s.mulated body conditions.was.ev.luated and s.owed that the alloy was.highly r.s.s.ant to cor.os.on deter.or.tion r.gar.les. of additional las.r.s.r.ace modification ***,the impr.v.d cor.os.on r.s.s.ance after.las.r.tr.atment was.ev.dent(the cor.os.on cur.ent dens.ty of the alloy befor. las.r.ir.adiation was.2.84×10^(−8)A/cm2,while that after.las.r.tr.atment with 5 mJ was.0.65×10^(−8)A/cm2)and as.r.bed to the r.pid for.ation of a complex and pas.iv.ting bi-modal s.r.ace oxide *** cytotoxicity and effects.of the Ti−45Nb alloy las.r.s.r.ace modification on the Mr.-5 cell v.ability,mor.hology,and pr.lifer.tion wer. als. *** Ti−45Nb alloy s.owed no cytotoxic ***,cells.s.owed impr.v.d v.ability and adher.nce to the alloy s.r.ace after.the las.r.ir.adiation *** highes. av.r.ge cell v.ability of 115.37%was.attained for.the alloy las.r.ir.adiated with 15 *** s.owed that the las.r.s.r.ace modification can be s.cces.fully utilized to s.gnificantly impr.v. alloy per.or.ance in a biological env.r.nment.

关键词： Ti−45Nb alloy las.r.s.r.ace s.anning electr.chemical pr.per.ies biocompatibility cell mor.hology

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Polar.ton las.ng in Mie-r.s.nant per.v.0}ite nanocav.ty

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Opto-Electr.nic Adv.nces 2024年第4期7卷 27-42页

作者： Mikhail A.Mas.ar.n Dar.a Khmelev.0}aia v.ler.y I.Kondr.tiev.Dar.a I.Mar.ina Anton D.Utyus.ev.Dmitr.y M.Dolgints.v.Alexey D.Dmitr.ev.v.nik A.s.ahnazar.an Anatoly P.Pus.kar.v.Fur.an Is.k Iv.n v.Ior.0} Iv.n A.s.elykh Hilmi v.Demir.Anton K.s.mus.v.s.r.ey v.Makar.25} UNAM-Ins.itute of Mater.als.s.ience and Nanotechnology National Nanotechnology Research CenterDepartment of Electrical and Electronics EngineeringDepartment of PhysicsBilkent UniversityAnkara 06800Turkey ITMO Univ.r.1}ty School of Physics and EngineeringSt.Petersburg 197101Russia Abr.kos.v.Center.for.Theor.tical Phys.cs MIPTDolgoprudnyiMoscow Region 141701Russia lUMINOUs.Center.of Excellence for.s.miconductor.lighting and Dis.lays School of Electrical and Electronic EngineeringSchool of Physical and Mathematical SciencesSchool of Materials Science and EngineeringNanyang Technological UniversitySingapore 639798Singapore Depar.ment of Phys.cs Engineering Physics and AstronomyQueen’s UniversityKingstonOntario K7L 3N6Canada s.ience Ins.itute University of IcelandDunhagi 3IS-107ReykjavikIceland Exper.mentelle Phys.k 2 Technische Universität DortmundDortmund 44227Germany Qingdao Innov.tion and Dev.lopment Center Harbin Engineering UniversityQingdao 266000China

Deeply s.bwav.length las.r.0}or.nanolas.r.0}ar. highly demanded for.compact on-chip bioimaging and s.ns.ng at the *** of the main obs.acles.for.the dev.lopment of s.ngle-par.icle nanolas.r.0}with all thr.e dimens.ons.s.or.er.than the emitting wav.length in the v.s.ble r.nge is.the high las.ng thr.s.olds.and the r.s.lting *** we ex-ploit exciton-polar.ton condens.tion and mir.or.image Mie modes.in a cuboid Cs.bBr. nanopar.icle to achiev. coher.nt emis.ion at the v.s.ble wav.length of ar.und 0.53μm fr.m its.ultr.-s.all(≈0.007μm3 or.λ3/20)s.miconductor.*** polar.tonic natur. of the emis.ion fr.m the nanocav.ty localized in all thr.e dimens.ons.is.pr.v.n by dir.ct com-par.s.n with cor.es.onding one-dimens.onal and two-dimens.onal wav.guiding s.s.ems.with s.milar.mater.al *** a deeply s.bwav.length nanolas.r.is.enabled not only by the high v.lues.for.exciton binding ener.y(≈35 mev.,r.-fr.ctiv. index(>2.5 at low temper.tur.),and lumines.ence quantum yield of Cs.bBr.,but als. by the optimization of po-lar.tons.condens.tion on the Mie r.s.nances.with quality factor.0}impr.v.d by the metallic ***,the key par.meter.0}for.optimal las.ng conditions.ar. inter.ode fr.e s.ectr.l r.nge and phonons.s.ectr.m in Cs.bBr.,which gov.r. polar.tons.condens.tion *** chemically s.nthes.zed colloidal Cs.bBr. nanolas.r.0}can be potentially de-pos.ted on ar.itr.r. s.r.aces.which makes.them a v.r.0}tile tool for.integr.tion with v.r.ous.on-chip s.s.ems.

关键词： nanolas.r per.v.0}ite polar.ton Mie r.s.nance exciton-polar.ton

Hydr.car.on indication in r.o Bonito For.ation s.nds.one:Implication for.CO_(2)s.or.ge in s.o Paulo,Br.zil

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Ener.y geos.ience 2024年第1期5卷 331-341页

作者： r.char.s.n M.Abr.ham-A Haline v.r.cha s.ulo B.de Oliv.ir. Colombo C.g.Tas.inar.i Or.ando C.da s.lv. Ins.itute of Ener.y and Env.r.nment University of São PauloSão PauloBrazil r.s.ar.h Centr. for.gr.enhous. gas.Innov.tion University of São PauloSão PauloBrazil

s.o Paulo s.ate has.witnes.ed CO_(2)s.or.ge-bas.d inv.s.igations.cons.der.ng the av.ilability of s.itable geologic s.r.ctur.s.and pr.ximity to pr.mar. CO_(2)s.ur.e s.nks.r.lated to bioener.y and car.on captur. and s.or.ge(BECCs.*** cur.ent s.udy pr.s.nts.the hydr.car.on v.ability ev.luations.and CO_(2)s.or.ge pr.s.ects.focus.ng on the s.nds.one units.of the r.o Bonito *** objectiv. is.to apply petr.phys.cal ev.luations.with geochemical inputs.in pr.dicting futur. hydr.car.on(gas.pr.duction to boos. CO_(2)s.or.ge within the s.udy *** s.udy us.d data fr.m elev.n wells.with as.ociated wir.line logs.gamma r.y,r.s.s.iv.ty,dens.ty,neutr.n,and s.nic)to pr.dict potential hydr.car.on accumulation and fluid mobility in the inv.s.igated *** s.mples.s.ale and car.onate)obtained fr.m depths.200 m within the s.udy location hav. s.own bitumen *** geochemis.r. data of the r.o Bonito For.ation s.ale beds.s.gges. they ar. potential hydr.car.on s.ur.e r.cks.and could hav. contr.buted to the gas.accumulations.within the s.nds.one *** dr.lled well data,e.g.,CB-1-s. and TI-1-s.,s.ow hydr.car.on(gas.pr.s.nce bas.d on the typical r.s.s.iv.ty and the combined neutr.n-dens.ty r.s.ons.s.at depths.up to 3400 m,indicating the pos.ibility of other.hydr.car.on member.0}apar. fr.m the heav. oil(bitumen)obs.r.6}d fr.m the near.s.r.ace r.cks.*** the thr.e-dimens.onal(3-D)model,the fr.e fluid indicator.FFI)is.mor. s.gnificant towar.s.the s.uthwes. and s.utheas. of the ar.a with deeper.depths.of occur.ence,indicating por.ions.with r.as.nable hydr.car.on r.cov.r. r.tes.and good pr.s.ects.for.CO_(2)injection,cir.ulation and per.anent ***,futur. s.udies.bas.d on contempor.r. datas.ts.ar. r.quir.d to es.ablis. the hydr.car.on v.ability fur.her.fos.er.gas.pr.duction ev.nts.and enhance CO_(2)s.or.ge pos.ibilities.within the r.gion.

关键词： Par.náBas.n Hydr.car.on indication s.nds.one r.s.r.3}ir. r.o Bonito For.ation CO_(2)s.or.ge Hydr.car.on r.cov.r. factor Fluid injection r.te