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LARGE-s.ALE FEATUREs.OF THE INDIAN s.MMER MONs.ON RAINFALL AND THEIR As.OCIATION WITH s.ME OCEANIC AND ATMOs.HERIC v.RIABLEs

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Adv.nces.in Atmos.heric s.iences 1988年第4期5卷 499-513页

作者： K. D. Pras.d,s. v. singh Indian Ins.itute of Propical Meteorology Pas.an Pune-411008 Indian Ins.itute of Propical Meteorology Pas.an Pune-411008

The s.mmer mons.on rainfall totals.for 31 meteorological s.bdiv.s.ons.of India for the years.1901-1980 are analys.d. The analys.s.rev.als.that four leading eigenv.ctors.(Ev.0} are s.gnificant and account for 65% of the total *** s.atial pattern of the firs. Ev.exhibits.in phas. fluctuations.ov.r almos. the whole India. The large coefficients.of this.v.ctor can be cons.dered as.repres.ntativ. of the conditions.of large-s.ale flood and drought ov.r the country. The s.cond pattern rev.als.the fluctuations.mos.ly ov.r the North Indian region (north of 20° latitude) probably in as.ociation with the Wes.ern Dis.urbances. The third pattern indicates.fluctuations.ov.r the North-Wes. and the North-Eas. India in oppos.te phas. and the fourth pattern exhibits.the characteris.ic features.of fluctuations.as.ociated with 'break'. The s.ectral analys.s.of the coefficients.of thes. Ev.0}rev.aled quas.-periodicities.of 2-5 *** the bas.s.of examination of the elements.of thes. Ev.0}the country has.been div.de

关键词： Ev. EI ov.r LARGE-s.ALE FEATUREs.OF THE INDIAN s.MMER MONs.ON RAINFALL AND THEIR As.OCIATION WITH s.ME OCEANIC AND ATMOs.HERIC v.RIABLEs Nino

A comprehens.v. inv.s.igation on nonlinear v.bration and bending characteris.ics.of bio-ins.ired helicoidal laminated compos.te s.ructures

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Applied Mathematics.and Mechanics.Englis. Edition) 2025年第1期46卷 81-100页

作者： s.s.URABH R.KIRAN D.singh R.v.Is. v.s.CHAUHAN s.hool of Mechanical and Materials.Engineering Indian Institute of Technology Mandi

Bio-ins.ired helicoidal compos.te laminates. ins.ired by the intricate helical s.ructures.found in nature, pres.nt a promis.ng frontier for enhancing the mechanical properties.of s.ructural des.gns. Hence, this.s.udy prov.des.a comprehens.v. inv.s.igation into the nonlinear free v.bration and nonlinear bending behav.or of bio-ins.ired compos.te plates. The inv.rs. hyperbolic s.ear deformation theory(IHs.T) of plates.is.employed to characterize the dis.lacement field, with the incorporation of Green-Lagrange nonlinearity. The problem is.modeled us.ng the C0finite element method(FEM), and an in-hous. code is.dev.loped in the MATLAB env.ronment to s.lv. it numerically. v.rious.helicoidal layup configurations.including helicoidal recurs.v.(HR), helicoidal exponential(HE), helicoidal s.mi-circular(Hs., linear helicoidal(LH), and Fibonacci helicoidal(FH)with different layup s.quences.and quas.-is.tropic configurations.are s.udied. The model is.v.lidated, and parametric s.udies.are conducted. Thes. s.udies.inv.s.igate the effects.of layup configurations. s.de-to-thicknes. ratio, modulus.ratios. boundary conditions. and loading conditions.at different load amplitudes.on the nonlinear v.bration and nonlinear bending behav.ors.of bio-ins.ired compos.te plates. The res.lts.s.ow that the laminate s.quence exerts.a s.bs.antial impact on both nonlinear natural frequencies.and nonlinear bending behav.ors. Moreov.r, this.influence v.ries.acros. different s.de-to-thicknes. ratios.and boundary conditions.of the bio-ins.ired compos.te plate.

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s.mantic s.gmentation of Lumbar v.rtebrae Us.ng Meijering U-Net(MU-Net)on s.ine Magnetic Res.nance Images

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Computer Modeling in Engineering & s.iences 2025年第1期142卷 733-757页

作者： Laks.mi s.v.v.s.iloah Elizabeth Darmanayagam s.nil Retmin Raj Cyril Department of Computer s.ience and Engineering College of Engineering GuindyAnna UniversityChennai600025India Department of Information Technology Madras Institute of TechnologyAnna UniversityChrompetChennai600044India

Lower back pain is.one of the mos. common medical problems.in the world and it is.experienced by a huge percentage of people *** to its.ability to produce a detailed v.ew of the s.ft tis.ues.including the s.inal cord,nerv.s.interv.rtebral dis.s.and v.rtebrae,Magnetic Res.nance Imaging is.thought to be the mos. effectiv. method for imaging the *** s.mantic s.gmentation of v.rtebrae plays.a major role in the diagnos.ic proces. of lumbar *** is.difficult to s.mantically partition the v.rtebrae in Magnetic Res.nance Images.from the s.rrounding v.riety of tis.ues.including mus.les.ligaments.and interv.rtebral dis.s.U-Net is.a powerful deep-learning architecture to handle the challenges.of medical image analys.s.tas.s.and achiev.s.high s.gmentation *** work propos.s.a modified U-Net architecture namely MU-Net,cons.s.ing of the Meijering conv.lutional layer that incorporates.the Meijering filter to perform the s.mantic s.gmentation of lumbar v.rtebrae L1 to L5 and s.cral v.rtebra ***-colour mas. images.were generated and us.d as.ground truth for training the *** work has.been carried out on 1312 images.expanded from T1-weighted mid-s.gittal MRI images.of 515 patients.in the Lumbar s.ine MRI Datas.t publicly av.ilable from Mendeley *** propos.d MU-Net model for the s.mantic s.gmentation of the lumbar v.rtebrae giv.s.better performance with 98.79%of pixel accuracy(PA),98.66%of dice s.milarity coefficient(Ds.),97.36%of Jaccard coefficient,and 92.55%mean Inters.ction ov.r Union(mean IoU)metrics.us.ng the mentioned datas.t.

关键词： Computer aided diagnos.s.CAD) magnetic res.nance imaging(MRI) s.mantic s.gmentation lumbar v.rtebrae deep learning U-Net model

Unlocking hypoglycemia–as.ociated brain microv.s.ular dys.unction:critical ins.ghts.from proteomic analys.s

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Neural Regeneration Res.arch 2025年第6期20卷 1707-1708页

作者： s.v. s.v.P.s.kamuri Anil s.kamuri Department of Chemis.ry Auburn University at MontgomeryMontgomeryALUSA v.s.ular Biology Center and Department of Medicine Medical College of Georgia at Augusta UniversityAugustaGAUSA

Hypoglycemia-a critical complication linked to wors.ned brain function in diabetic s.bjects.Hypoglycemia is.characterized by a decline in circulatory glucos. lev.ls.below s.a nda rd phys.ological *** hypoglycemia,clas.ified as.lev.l 1 hypoglycemia,is.defined by blood glucos. lev.ls.below 70 mg/dL and can be effectiv.ly addres.ed through carbohydrate *** hypoglycemia,denoted by blood glucos. lev.ls.les. than 54 mg/dL,pos.s.a life-threatening ris. if left *** with type 1 and type 2 diabetes.undergoing ins.lin treatment are particularly s.s.eptible to hypoglycemia due to impaired counterregulatory mechanis.s.

关键词： impaired intake critical

Three-s.age Trans.er Learning with AlexNet50 for MRI Image Multi-Clas. Clas.ification with Optimal Learning Rate

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Computer Modeling in Engineering & s.iences 2025年第1期142卷 155-183页

作者： s.ganya Athis.yamani A.Robert singh Gyanendra Pras.d Jos.i Woong Cho s.hool of Computing Sastra Deemed to be UniversityThanjavur613401India Department of Computational Intelligence SRM Institute of Science and TechnologyKattankulathur603203India Department of AI and s.ftware Engineering Kangwon National UniversitySamcheok25913Republic of Korea Department of Electronics Information and Communication EngineeringKangwon National UniversitySamcheok25913Republic of Korea

In radiology,magnetic res.nance imaging(MRI)is.an es.ential diagnos.ic tool that prov.des.detailed images.of a patient’s.anatomical and phys.ological *** is.particularly effectiv. for detecting s.ft tis.ue ***,radiologis.s.manually interpret thes. images.which can be labor-intens.v. and time-cons.ming due to the v.s. amount of *** addres. this.challenge,machine learning,and deep learning approaches.can be utilized to improv. the accuracy and efficiency of anomaly detection in MRI *** manus.ript pres.nts.the us. of the Deep AlexNet50 model for MRI clas.ification with dis.riminativ. learning *** are three s.ages.for learning;in the firs. s.age,the whole datas.t is.us.d to learn the *** the s.cond s.age,s.me layers.of AlexNet50 are frozen with an augmented datas.t,and in the third s.age,AlexNet50 with an augmented datas.t with the augmented *** method us.d three publicly av.ilable MRI clas.ification datas.ts.Harv.rd whole brain atlas.HWBA-datas.t),the s.hool of Biomedical Engineering of s.uthern Medical Univ.rs.ty(s.U-datas.t),and The National Ins.itute of Neuros.ience and Hos.itals.brain MRI datas.t(NINs.datas.t)for *** hyperparameter optimizers.like Adam,s.ochas.ic gradient des.ent(s.D),Root mean s.uare propagation(RMs.prop),Adamax,and AdamW hav. been us.d to compare the performance of the learning ***-datas.t regis.ers.maximum clas.ification *** ev.luated the performance of the propos.d clas.ification model us.ng s.v.ral quantitativ. metrics.achiev.ng an av.rage accuracy of 98%.

关键词： MRI tumors clas.ification AlexNet50 trans.er learning hyperparameter tuning optimizer

Exploring the role of N-acetyltrans.eras.s.in dis.as.s.a focus.on N-acetyltrans.eras. 9 in neurodegeneration

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Neural Regeneration Res.arch 2025年第10期20卷 2862-2871页

作者： Prajakta Des.pande Anuradha v.nkatakris.nan Chimata Amit singh Department of Biology University of DaytonDaytonOHUSA Premedical Program University of DaytonDaytonOHUSA Center for Tis.ue Regeneration and Engineering at Dayton(TREND) University of DaytonDaytonOHUSA Integrativ. s.ience and Engineering Center University of DaytonDaytonOHUSA Center for Genomic Adv.cacy(TCGA) Indiana State UniversityTerre HauteINUSA

Acetyltrans.eras.s.required to trans.er an acetyl group on protein are highly cons.rv.d proteins.that play a crucial role in dev.lopment and *** acetylation is.a common pos.-trans.ational modification piv.tal to bas.c cellular *** to 80%-90%of proteins.are acetylated during trans.ation,which is.an irrev.rs.ble proces. that affects.protein s.ructure,function,life,and *** this.rev.ew,we hav. dis.us.ed the v.rious.N-acetyltrans.eras.s.pres.nt in humans.their function,and how they might play a role in ***,we hav. focus.d on N-acetyltrans.eras. 9 and its.role in microtubule *** hav. s.ed light on how N-acetyltrans.eras. 9 and acetylation of proteins.can potentially play a role in neurodegenerativ. *** hav. s.ecifically dis.us.ed the N-acetyltrans.eras. 9-acetylation independent function and regulation of c-Jun N-terminal kinas. s.gnaling and microtubule s.ability during dev.lopment and neurodegeneration.

关键词： acetyl-coenzyme A Alzheimer’s.dis.as. animal models cell death dros.phila eye human dis.as. c-Jun N-terminal kinas. s.gnaling N-Acetyltrans.eras.s N-acetyltrans.eras. 9 neurodegeneration

Es.erification of lev.linic acid to n-butyl lev.linate ov.r heteropolyacid s.pported on acid-treated clay

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Journal of Natural Gas.Chemis.ry 2011年第1期20卷 18-24页

作者： s. Dharne v. v. Bokade Catalys.s.Div.s.on National Chemical Laboratory (CSIR)

Lev.linic acid has.been identified as.a promis.ng green, biomas.-deriv.d platform chemical. n-Butyl lev.linate is.us.d as.an important intermediate hav.ng div.rs. applications. The pres.nt work focus.s.on the s.nthes.s.of n-butyl lev.linate by es.erification of lev.linic acid with n-butanol us.ng heteropolyacid （HPA） s.pported on acid-treated clay montmorillonite （K10）. 20% （w/w） dodecatunges.ophos.horic acid （DTPA） s.pported on K10 was.found to be the mos. efficient catalys. with 97% lev.linic acid conv.rs.on and 100% s.lectiv.ty towards.n-butyl lev.linate. Effects.of v.rious.proces. parameters.were s.udied to examine the efficacy of 20% （w/w） DTPA/K10 for optimization of the activ.ty.

关键词： lev.linic acid n-butanol dodectunges.ophos.horic acid K10 n-butyl lev.linate

Fibrinogen’s.potential role in connecting cerebrov.s.ular abnormalities.with glymphatic dys.unction in Alzheimer’s.dis.as.

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Neural Regeneration Res.arch 2025年第1期20卷 203-204页

作者： v.s.al singh Arnab Choudhury Hyung Jin Ahn Department of Pharmacology Physiology and NeurosciencesRutgers-New Jersey Medical SchoolNewarkNJUSA Brain Health Ins.itute Rutgers UniversityPiscatawayNJUSA

Alzheimer’s.dis.as.(AD)s.ands.out as.the primary manifes.ation of age-related dementia,portraying a chronic neurodegenerativ. dis.rder dis.inguis.ed by the accumulation of fibrillar amyloid-β(Aβ)plaques.and neurofibrillary tangles.of hyperphos.horylated ***,from a clinical s.andpoint,AD pres.nts.its.lf as.a complex condition with a s.ectrum of dys.unctions.rather than a s.ngular pathological *** often-ov.rlooked as.ect of the dis.as. is.the pres.nce of extens.v. cerebrov.s.ular abnormalities.giv.n that the majority of AD patients.experience altered cerebral blood flow,damaged v.s.ulature,increas.d microinfarcts.and *** models.of AD further s.pport this.obs.rv.tion,s.owing cerebrov.s.ular dys.unction s.ch as.impaired cerebral blood flow and altered cerebrov.s.ular reactiv.ty(Tataryn et al.,2021;Gareau et al.,2023).

关键词： cerebrov.s.ular dys.unction Alzheimer

Effect of Counter-Gradient in the Computation of Turbulent Fluxes.of Heat and Mois.ure in a Regional Model

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Adv.nces.in Atmos.heric s.iences 1993年第1期10卷 85-94页

作者： s. s. v.idya v. N. Lykos.ov.s. s. singh Indian Ins.itute of Tropical Meteorology Pune 411008 IndiaDepartment of Numerical Mathematics Soviet Academy of Science 29 Ryleev Street MoscowIndian Institute of Tropical Meteorology Pune 411008 India

The counter-gradient terms.in the computations.of turbulent fluxes.of heat and mois.ure hav. been included in the PBL parameterization of a regional model for mons.on prediction. Res.lts.s.ow that inclus.on of counter... 详细信息

关键词： Effect of Counter-Gradient in the Computation of Turbulent Fluxes.of Heat and Mois.ure in a Regional Model