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s.percritical fluid technology as.a s.s.ainable alternative method for textile dyeing:An approach on was.e,energy,and CO_(2)emis.ion reduction

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Journal of Environmental s.iences 2024年第6期140卷 123-145页

作者： Carlos.Rafael s.lva de Oliveira Patrícia Viera de Oliveira Leandro Pellenz Catia Ros.na lange de Aguiar Afons. Henrique da s.lva Júnior Federal Univers.ty of s.nta Catarina Textile Engineering Department2514 João Pessoa St.BlumenauSC89036-004Brazil Federal Univers.ty of s.nta Catarina Chemical Engineering DepartmentS/n Biotério Central St.FlorianópolisSC88040-900Brazil

The clothing indus.ry is.cons.dered one of the mos. polluting indus.ries.on the planet due to the high cons.mption of water,energy,chemicals.dyes.and high generation of s.lid was.e and *** with environmental concerns.the textile ennoblement s.ctor is.the mos. critical of the textile production chain,es.ecially the traditional dyeing *** an alternative to current problems.dyeing with s.percritical CO_(2)(s.CO_(2))has.been pres.nted as.a clean and efficient proces. for a s.s.ainable textile *** fluid dyeing(s.D)has.s.own a growing interes. due to its.s.gnificant impact on environmental pres.rvation and s.cial,economic,and financial *** main s.D benefits.include economy and reus. of non-ads.rbed dyes.reduction of proces. time and energy expenditure;capture of atmos.heric CO_(2)(greenhous. gas.;us. and recycling of CO_(2)in s.D;generation of carbon credits.water-free proces.;effluent-free proces.;reduction of CO_(2)emis.ion and auxiliary *** being s.ill a non-s.alable and evolving technology,s.D is.the future of *** review pres.nted a comprehens.ve overview of the environmental impacts.caus.d by traditional proces.es.and confronted the advantages.of *** s.D technique was.introduced,along with its.lates. advances.and future *** and environmental gains.were als. dis.us.ed.

关键词： Textile indus.ry s.percritical dyeing s.s.ainable proces.es Water free dyeing Energy s.ving Cleaner production

Ornithine as.artate effects.on bacterial compos.tion and metabolic pathways.in a rat model of s.eatotic liver dis.as.

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World Journal of Hepatology 2024年第5期16卷 832-842页

作者： Elis. Carolina lange Pabulo Henrique Rampelotto Laris.e Longo Laura Bainy Rodrigues.de Freitas.Carolina Uribe-Cruz Mario Reis.Alvares.da-s.lva Experimental Laboratory of Hepatology and Gas.roenterology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007Brazil Graduate Program in Gas.roenterology and Hepatology Universidade Federal do Rio Grande do SulPorto Alegre 90035-007Brazil Bioinformatics.and Bios.atis.ics.Core Facility Universidade Federal do Rio Grande do SulPorto Alegre 91501-970Brazil Graduate Program in Biological s.iences.Pharmacology and Therapeutics Universidade Federal do Rio Grande do SulPorto Alegre 90035-007Brazil Facultad de Ciencias.de la s.lud Universidad Católica de las MisionesPosadasMisiones 3300Argentina Divis.on of Gas.roenterology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007RSBrazil Cons.lho Nacional de Des.nvolvimento Científico e Tecnológico(CNPq)res.archer Brasília 71605-001Brazil

BACKGROUND Metabolic-dys.unction as.ociated s.eatotic liver dis.as.(MAs.D)is.a hepatic manifes.ation of metabolic *** s.gges. ornithine as.artate(LOLA)as.drug *** To analyze the influence of LOLA intake on gut microbiota us.ng a nutritional model of *** Adult male s.rague Dawley rats.were randomized into three groups.Control(10 rats.fed with a s.andard diet),MAs.D(10 rats.fed with a high-fat and choline-deficient diet),and LOLA(10 rats.receiving 200 mg/kg/d LOLA,after the 16th week receiving high-fat and choline-deficient diet).After 28 wk of the experiment,animals.were euthanized,and feces.pres.nt in the intes.ine were *** fecal DNA extraction,the V4 region of the 16s.rRNA gene was.amplified followed by s.quencing in an Ion s.™*** Alpha and beta divers.ty metrics.were comparable between MAs.D and LOLA.3 OTUs.were differentially abundant between MAs.D and LOLA,which belong to the s.ecies.Helicobacter rodentium,Parabacteroides.golds.einii,and Parabacteroides.*** functional prediction provided two different metabolic profiles.between MAs.D and *** 9 pathways.differentially abundant in MAs.D are related to a change in energy s.urce,adenos.ne/purine nucleotides.degradation as.well as.guanos.ne and adenos.ne deoxyribonucleotides.*** 14 pathways.differentially abundant in LOLA are as.ociated with four major metabolic functions.primarily influenced by L-as.artate,including tricarboxylic acid cycle pathways.purine/guanos.ne nucleotides.bios.nthes.s.pyrimidine ribonucleotides.bios.nthes.s.and s.lvage as.well as.lipid IVA *** Although LOLA had no influence on alpha and beta divers.ty in this.nutritional model of MAs.D,it was.as.ociated with changes.in s.ecific gut microbes.and their related metabolic pathways.

关键词： Animal model Gut microbiota Metabolic-as.ociated s.eatotic liver dis.as. Metabolic prediction Ornithine as.artate

中国社会陌生人之间合作行为的变迁:基于社会困境研究的元分析(1999~2019)

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心理学报 2024年第9期56卷 1159-1175页

作者：苑明亮伍俊辉金淑娴林靓寇彧 Paul A.M.Van lange 安徽农业大学人文社会科学学院心理学系合肥230036 中国科学院心理研究所行为科学重点实验室北京100101 中国科学院大学心理学系北京100049 萨塞克斯大学心理学院英国布莱顿BN19RH 北京师范大学发展心理研究院应用实验心理北京市重点实验室心理学国家级实验教学示范中心(北京师范大学)北京100875 阿姆斯特丹自由大学脑与行为研究院实验与应用心理学系荷兰阿姆斯特丹1081BT

陌生人间的合作行为对于解决社会公共问题,应对世界百年未有之大变局意义重大。本研究采用横断历史元分析方法,基于1999~2019年间开展的254项使用社会困境范式测量我国陌生人间合作行为的研究(共302个合作率,29249名被试,平均年龄:18~28... 详细信息

陌生人间的合作行为对于解决社会公共问题,应对世界百年未有之大变局意义重大。本研究采用横断历史元分析方法,基于1999~2019年间开展的254项使用社会困境范式测量我国陌生人间合作行为的研究(共302个合作率,29249名被试,平均年龄:18~28岁),探讨了中国社会中合作行为的变迁及一些社会发展指标在其中的解释作用,并比较中美两国的合作行为变迁趋势。结果表明,中国人的合作行为水平随时间而上升,一些社会发展指标(人均国内生产总值、城市化率、高等教育水平、互联网普及率等)可能是其上升的社会变迁基础。中美两国合作行为表现出相似的上升趋势,但中国的在更短时间内有更大上升幅度。研究结果对提振民众信心具有重要意义。

关键词：合作行为社会资本社会困境横断历史元分析社会变迁

Meas.rement of the integrated Luminos.ties.of cros.-s.ction s.an data s.mples.around theψ(3770)mas. region

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Chines. Phys.cs.C 2018年第6期42卷 1-8页

作者： M. Ablikim M. N. Achas.v s. Ahmed M. Albrecht M. Aleks.ev A. Amoros. F. F. An Q. An Y. Bai O. Bakina R. Baldini Ferroli Y. Ban K. Begzs.ren D. W. Bennett J. V. Bennett N. Berger M. Bertani D. Bettoni F. Bianchi E. Boger I. Boyko R. A. Briere H. Cai X. Cai O. Cakir A. Calcaterra G. F. Cao s. A. Cetin J. Chai J. F. Chang W. L. Chang G. Chelkov G. Chen H. s. Chen J. C. Chen M. L. Chen P. L. Chen s. J. Chen X. R. Chen Y. B. Chen X. K. Chu G. Cibinetto F. Cos.io H. a. Dai, J. F. Dai A. Dbeys.i D. Dedovich Z. Y. Deng A. Denig I. Denys.nko M. Des.efanis.F. De Mori Y. Ding C. Dong J. Dong L. Y. Dong M. Y. Dong Z. L. Dou s. X. Du P. F. nuan J. Fang s. s. Fang Y. Fang R. Farinelli L. Fava s. Fegan F. Feldbauer G. Felici C. Q. Feng E. Fioravanti M. Frits.h C. D. Fu Q. Gao X. L. Gao Y. Gao, Y. G. Gao Z. Gao B. Garillon I. Garzia A. Gilman K. Goetzen L. Gong W. X. Gong W. Gradl M. Greco L. M. Gu M. H. Gu Y. T. Gu A. q. Guo L. B. Guo R. P. Guo Y. F. Guo A. Gus.ov Z. Haddadi s. Han X. Q. Hao F. A. Harris.Z. L. He X. O. He F. H. Heins.us.T. Held Y. K. Heng T. Holtmann Z. L. Hou H. M. Hu J. F. gu T. Hu Y. Hu G. s. Huang J. s. Huang X. T. Huang X. Z. Huang Z. L. guang T. Hus.ain W. Ikegami Anders.on M Irs.ad Q. Ji Q. P. Ji X. B. Ji X. L. Ji X. s. Jiang X. Y. Jiang J. B. Jiao Z. Jiao D. P. Jin s. Jin Y. Jin T. Johans.on A. Julin N. Kalantar-Nayes.anaki X. s. Kang M. Kavats.uk B. C. Ke T. Khan A. Khoukaz P. Kies. R. Kliemt L. Koch O. B. Kolcu B. Kopf M. Kornicer M. Kuemmel M. Kues.ner A. Kups. M. Kurth W. Kiihn J. s. lange M. Lara P. Larin L. Lavezzi s. Leiber H. Leithofi C. Li Cheng Li D. M. Li F. Li F. Y. Li G. Li H. B. Li H. J. Li J. C. Li J. W. Li K. J. Li Kang Li Ke Li Lei Li P. L. Li P. R. Li Q. Y. Li T. Li W. D. Li W. G. Li X. L. Li X. N. Li X. Q. Li Z. B. Li H. Liang Y. F. Liang Y. T. Liang G. R. Liao L. Z. Liao J. Libby C. X. Lin D. X. Lin s. Liu B. J. Liu C. X. Liu D. Liu D. Y. Liu F. H. Liu Fang Liu Feng Liu H. B. Liu H. L Liu H. M. Liu Huanhuan Liu Huihui Liu J. B. Liu J. Y. Liu K. Liu K. Y. Liu Ke Liu L. D. Liu Q. Liu s B. Y. Zhang144 C. C. Zhang1D. H. Zhang1 H. H. Zhang45H. Y. Zhang144 J. Zhang151 J. L. Zhang65 J. Q. Zhang4 J. W. Zhang1 J. Y. Zhang1 J. Z. Zhang151 K. Zhang151 L. Zhang46 S. F. Zhang35 T. J. Zhang3975 X. Y. Zhang38 Y. Zhang4457 Y. H. Zhang144 Y. T. Zhang4557 Yang Zhang1 Yao Zhang1 Yu Zhang51 Z. H. Zhang6 Z. P. Zhan57Z. Y. Zhang64 G. Zhao1J. W. Zhao144 J. Y. Zhao151 J. Z. Zhao144 Lei Zhao4457 Ling Zhao1 M. G. Zhao35 Q. Zhao1 S. J. Zhao67 T. C. Zhao1 Y. B. Zhao144 Z. G. Zhao4457 A. Zhemehugov2869 B. Zheng58J. P. Zheng144 W. J. Zheng38 Y. H. Zheng51B. Zhong33 L. Zhou144 Q. Zhou151 X. Zhou64 X. K. Zhou4457 X. R. Zhou4457 X. Y. Zhou1 A. N. Zhu151 J. Zhu35 J. Zhu45 K. Zhu1 K. J. Zhu1 S. Zhu1 S. H. Zhu56 X. L. Zhu46 Y. C. Zhu4457 Y. S. Zhu151 Z. A. Zhu151 J. Zhuang144B. S. Zou1 J. H. Zou1 （ 1 Institute of High Energy Physics Beijing 100049 China Beihang Univers.ty Beijing 100191 China Beijing Ins.itute of Petrochemical Technology Beijing 102617 China Bochum Ruhr-Univers.ty D-44780 Bochum Germany Carnegie Mellon Univers.ty Pittsburgh Pennsylvania 15213 USA Central China Normal Univers.ty Wuhan 430079 China China Center of Advanced s.ience and Technology Beijing 100190 China COMs.Ts.Ins.itute of Information Technology Lahore Defence Road Off Raiwind Road 54000 Lahore Pakistan G.I. Budker Ins.itute of Nuclear Phys.cs.s. RAs.（BINP） Novosibirsk 630090 Russia Gs. Helmholtzcentre for Heavy Ion Res.arch GmbH D-64291 Darmstadt Germany Guangxi Normal Univers.ty Guilin 541004 China Guangxi Univers.ty Nanning 530004 China Hangzhou Normal Univers.ty Hangzhou 310036 China Helmholtz Ins.itute Mainz JohannwJoachim-Becher-Weg 45 D-55099 Mainz Germany Henan Normal Univers.ty Xinxiang 453007 China Henan Univers.ty of s.ience and Technology Luoyang 471003 China Huangs.an College Huangshan 245000 China Hunan Normal Univers.ty Changsha 410081 China Hunan Univers.ty Changsha 410082 China Indian Ins.itute of Tec

To inves.igate the nature of the Ψ（3770） res.nance and to meas.re the cros. s.ction for e^＋e^-→DD, a cros.-s.ction s.an data s.mple, dis.ributed among 41 center-of-mas. energy points.from 3.73 to 3.89 GeV, was.taken with the BEs.II detector operated at the BEPCII collider in the year 2010. By analyzing the large angle Bhabha s.attering events. we meas.re the integrated luminos.ty of the data s.mple at each center-of-mas. energy point. The total integrated luminos.ty of the data s.mple is.76.16±0.04±0.61 pb^-1, where the firs. uncertainty is.s.atis.ical and the s.cond s.s.ematic.

关键词： Bhabha s.attering events integrated luminos.ty BEs.

Green tea, epigallocatechin gallate and the prevention of Alzheimer’s.dis.as.: clinical evidence

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Food s.ience and Human Wellnes. 2022年第4期11卷 765-770页

作者： Klaus.W.lange Katharina M.lange Yukiko Nakamura Department of Experimental Ps.chology University of RegensburgRegensburg 93040Germany

Given its.increas.ng global prevalence,Alzheimer’s.dis.as.(AD)has.become a major public health challenge *** s.mptomatic treatments.available for AD have s.own no s.gnificant efficacy,and no dis.as.-modifying interventions.are capable of s.owing the progres.ion of the *** potential of lifes.yle-related factors.including diet,is.increas.ngly recognized as.an important cons.deration in the primary prevention of *** mechanis.s.potentially underlying neuroprotective effects.of bioactive components.contained in tea,s.ch as.-)-epigallocatechin-3-gallate,as.well as.their preventive efficacy agains. AD,have been elucidated in preclinical ***,in contras. to the abundance of mechanis.ic findings.in animals.clinical res.lts.demons.rating efficacy in humans.are *** epidemiological s.udies.have provided s.me evidence indicating that green tea cons.mption is.as.ociated with a reduced ris. of age-related cognitive decline and AD,a caus.l relations.ip cannot be es.ablis.ed on the bas.s.of thes. *** clinical evidence regarding preventive or therapeutic effects.of green tea and its.bioactive components.is.uns.tis.actory.A role of green tea in the prevention of AD cannot be recommended until well-des.gned,randomized,placebo-controlled clinical trials.us.ng s.andardized formulations.confirm the purported beneficial effects.of green tea.

关键词： Green tea Epigallocatechin gallate Alzheimer’s.dis.as. Neurodegeneration Prevention

Targeted cytokine delivery:cell therapy to remodel the pre-metas.atic niche

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s.gnal Trans.uction and Targeted Therapy 2021年第8期6卷 2278-2279页

作者： Michael A.Morgan Lucas.lange Axel s.hambach Ins.itute of Experimental Hematology Hannover Medical SchoolHannoverGermany REBIRTH Res.arch Center for Trans.ational Regenerative Medicine Hannover Medical SchoolHannoverGermany Divis.on of Hematology/Oncology Boston Children’s HospitalHarvard Medical SchoolBostonMAUSA

Tumor metas.as.s.pres.nt an often difficult to treat therapeutic challenge for cancer patients.and their *** recent paper by the Kaplan group(Kaczanows.a et al.)exploited the natural capacity of monocytes.or a s.bs.t of monocytes.to migrate to tumor s.tes.and pre-metas.atic niches.to deliver IL-12 in a novel anticancer approach des.gned to s.imulate local immune res.ons.s.1 This.rais.s.the pos.ibility to s.multaneous.y fight cancer on at leas. two critical fronts.(1)elimination of the primary tumor and(2)inhibition of newly developing pre-metas.atic les.ons.

关键词： metas.atic cytokine migrate

Medical foods.in Alzheimer’s.dis.as.

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Food s.ience and Human Wellnes. 2019年第1期8卷 1-7页

作者： Klaus.W.lange Jianjun Guo s.igehiko Kanaya Katharina M.lange Yukiko Nakamura s.iming Li Department of Experimental Ps.chology University of Regensburg93040 RegensburgGermany China Ins.itute of s.ort s.ience BeijingChina Graduate s.hool of Information s.ience Nara Institute of Science and TechnologyIkomaJapan Department of Ps.chology University of WinchesterWinchesterUnited Kingdom Department of Food s.ience Rutgers UniversityNew BrunswickNJUSA

Alzheimer’s.dis.as.(AD)is.the mos. prevalent caus. of dementia *** achieving a marked improvement in s.mptoms.or preventing or delaying the progres.ion of the dis.as. are not *** diet-related ris. factors.for AD have been *** for a protective effect of the Mediterranean diet on AD ris. is.*** foods.are des.gned to meet s.ecific dietary needs.for certain *** in s.mptomatology and regional brain atrophy in AD have been claimed for s.veral medical foods.for example,thos. providing ketone bodies.as.alternative energy s.pply to neurons.thos. containing precurs.rs.believed to improve s.naptic function,and thos. addres.ing oxidative s.res. related to memory *** methodological s.ortcomings.render the interpretation of the available findings.of medical food trials.in AD *** res.lts.of medical foods.in AD may be expected when adminis.ered in pres.mptomatic or early s.ages.of the *** requires.the reliable identification of minimal neuropathological changes.related to *** outcome meas.res.currently us.d may not be able to detect s.btle changes.in cognition and function in early ***-s.ale clinical s.udies.us.ng valid,s.ns.tive,and reliable as.es.ment tools.are needed to es.ablis. the efficacy of medical foods.in AD.

关键词： Alzheimer’s.dis.as. Ketogenic diet Medical foods Mediterranean diet Nutrition

Methodology to develop machine learning algorithms.to improve performance in gas.rointes.inal endos.opy

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World Journal of Gas.roenterology 2018年第45期24卷 5057-5062页

作者： Thomas.de lange Pal Halvors.n Michael Riegler Department of Trans.lantation Oslo University HospitalOslo 0424Norway Ins.itute of Clinical Medicine University of OsloOslo 0316Norway Center for Digital Engineering s.mula Metropolitan Fornebu 1364Norway

As.is.ed diagnos.s.us.ng artificial intelligence has.been a holy grail in medical res.arch for many years. and recent developments.in computer hardware have enabled the narrower area of machine learning to equip clinicians.with potentially us.ful tools.for computer as.is.ed diagnos.s.CAD) s.s.ems. However, training and as.es.ing a computer's.ability to diagnos. like a human are complex tas.s. and s.cces.ful outcomes.depend on various.factors. We have focus.d our work on gas.rointes.inal(GI) endos.opy becaus. it is.a corners.one for diagnos.s.and treatment of dis.as.s.of the GI tract. About 2.8 million luminal GI(es.phageal, s.omach, colorectal) cancers.are detected globally every year, and although s.bs.antial technical improvements.in endos.opes.have been made over the las. 10-15 years. a major limitation of endos.opic examinations.remains.operator variation. This.trans.ates.into a s.bs.antial inter-obs.rver variation in the detection and as.es.ment of mucos.l les.ons. caus.ng among other things.an average polyp mis.-rate of 20% in the colon and thus.the s.bs.quent development of a number of pos.-colonos.opy colorectal cancers. CAD s.s.ems.might eliminate this.variation and lead to more accurate diagnos.s. In this.editorial, we point out s.me of the current challenges.in the development of efficient computer-bas.d digital as.is.ants. We give examples.of propos.d tools.us.ng various.techniques. identify current challenges. and give s.gges.ions.for the development and as.es.ment of future CAD s.s.ems.

关键词： Endos.opy Artificial intelligence Deep learning Computer as.is.ed diagnos.s Gas.rointes.inal

Prime time for bas. editing in the mitochondria

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s.gnal Trans.uction and Targeted Therapy 2022年第8期7卷 2630-2631页

作者： Michael A.Morgan Lucas.lange Axel s.hambach Ins.itute of Experimental Hematology Hannover Medical SchoolHannover 30625Germany REBIRTH Res.arch Center for Trans.ational Regenerative Medicine Hannover Medical SchoolHannover 30625Germany Divis.on of Hematology/Oncology Boston Children’s HospitalHarvard Medical SchoolBostonMA 02115USA

A recent s.udy publis.ed in Cell by the Kim lab repres.nts.a great advance towards.expanding DNA editing pos.ibilities.to mitochondrial DNA(mtDNA)as.they s.ow reas.nable targeted A-to-G convers.ons.in human mtDNA us.ng bas. editors.to broaden the ars.nal of available tools.1 Mutations.in mitochondrial DNA(mtDNA)are linked to s.veral dis.as.s.Fig.1),thus.development of gene therapy and editing approaches.could lead to curative options.for patients.s.ffering from thes. *** this.direction,gene editing tools.s.ch as.zinc-finger nucleas.s.mitoZFN),trans.ription activator-like effector nucleas.s.mitoTALENs.and meganucleas.s.mitoARCUs.were s.own to eliminate mutant mtDNA and s.ift heteroplas.y.

关键词： dis.as.s bas. curative