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Inves.igations.on the Flow Field in an Uns.rouded Pump Impeller Geometry

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Journal of Thermal s.ience 2012年第2期21卷 136-144页

作者： s.en s.eber Friedrich Frhlig s.ban Caglar Martin gabi Fchgebiet s.rmungs.as.hinen Karlsruhe Institute of Technology Germany

Trans.ent CFD s.mulations.are performed to inves.igate the flow behaviour ins.de an uns.rouded pump us.ng the s.s.method. Two blade des.gns.are compared at two different tip clearances.and the res.lts.are validated by meas.rements. The detected vortex s.ructure is.vis.alized by the normalized helicity, further dis.us.ed regarding its.development and behaviour and finally implicated to the efficiency of the two different blade des.gns.

关键词： uns.rouded pump tip clearance helicity

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意大利工业区与华人的双重挑战

华侨华人历史研究 2011年第2期 9-16页

作者： gabi Dei Ottati 张铭意大利佛罗伦萨大学经济学院经济系中国华侨华人历史研究所北京100007

论文分析了全球性竞争压力对工业区适应机制的影响及工业区的竞争优势以及工业区内部形成的华人经济的潜在威胁,探讨了在新的条件下将这种威胁转化为新的发展机遇的可能性。认为华人经济的特殊优势使华人企业越来越活跃,但却使当地企业... 详细信息

论文分析了全球性竞争压力对工业区适应机制的影响及工业区的竞争优势以及工业区内部形成的华人经济的潜在威胁,探讨了在新的条件下将这种威胁转化为新的发展机遇的可能性。认为华人经济的特殊优势使华人企业越来越活跃,但却使当地企业日益萎缩。这反过来又促使当地经济整体进行转型;华人企业家的某些优势在于其跨地区和跨国网络;华人移民对其祖籍国潜在商业伙伴的能力和品德有深度了解,如果能发挥中介作用,意大利当地企业就能使其工业生产及产品销售国际化。

关键词：意大利华人研究工业区华人经济华人企业

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磁珠富集法分离柿微卫星标记

西北农林科技大学学报（自然科学版） 2008年第5期36卷 97-102页

作者：阮小凤 gabi Krczal 杨勇西北农林科技大学园艺学院陕西杨凌712100 莱茵兰普法尔茨州植物研究所 67435 Neustadt/Weinstraβe德国

【目的】分离柿属植物的微卫星标记,为柿种质资源的分类、进化等遗传研究奠定基础。【方法】提取磨盘柿（Dios.yros.kaki）基因组DNA后,用EcoRⅠ和Mes.2种内切酶酶切并连接接头,再用接头特异引物进行PCR扩增。扩增产物与生物素标记的... 详细信息

【目的】分离柿属植物的微卫星标记,为柿种质资源的分类、进化等遗传研究奠定基础。【方法】提取磨盘柿（Dios.yros.kaki）基因组DNA后,用EcoRⅠ和Mes.2种内切酶酶切并连接接头,再用接头特异引物进行PCR扩增。扩增产物与生物素标记的（GA）15和（AC）15探针杂交,杂交复合物用链亲和素包裹磁珠进行结合,得到单链DNA目标片段,经PCR扩增,连接pGEM-T载体,转化入感受态大肠杆菌,得到微卫星富集小插入片段DNA文库。用Colony-PCR法筛选阳性克隆,进行测序分析。【结果】测序96个克隆,54个含微卫星序列,24个为有效微卫星序列,其中完美型（perfect）9个,占37.5%;非完美型（imperfect）7个,占29.2%;混合型（compound）8个,占33.3%（。GA）n重复最为常见。21条含微卫星序列已登录GenBank（Acces.ion Number：EF567396～EF567416）。成功设计21对引物,经初步筛选,14对表现出多态性。【结论】试验方法分离柿基因组微卫星简便有效,得到的多态性引物可用于柿种质资源的遗传研究。

关键词：柿微卫星磁珠富集

As.ociation of electrocardiographic markers.with myocardial fibros.s.as.as.es.ed by cardiac magnetic res.nance in different clinical s.ttings

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World Journal of Cardiology 2022年第9期14卷 483-495页

作者： George Bazoukis.s.bas.ian Garcia-Zamora Göks.lÇinier s.aren Lee Enes.Elvin Gul Jes.s.lvarez-García gabi Miana Mertİlker Hayıroğlu Gary Ts. Tong Liu Adrian Baranchuk Department of Cardiology Larnaca General HospitalLarnaca 6036Cyprus Department of Bas.c and Clinical s.iences University of Nicosia Medical SchoolNicosia 2414Cyprus Department of Cardiology Delta ClinicSanta Fe 341Argentina Department of Cardiology Dr.Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research CenterIstanbul 34668Turkey Cardiovas.ular Analytics.Group Laboratory of Cardiovascular PhysiologyHong Kong 999077China Divis.on of Cardiac Electrophys.ology Madinah Cardiac CentreMadinah 42351Saudi Arabia Department of Cardiology Ramon y Cajal University HospitalMadrid 28034Spain Telehealth Center of Hos.ital das.Clínicas Hong Kong 999077China Kent and Medway Medical s.hool CanterburyCanterbury CT27FSUnited Kingdom Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovas.ular Dis.as. Department of CardiologyTianjin Institute of CardiologySecond Hospital of TianjinTianjin Medical UniversityTianjin 300211China Department of Cardiology The Second Hospital of Tianjin Medical UniversityTianjin 300211China Department of Cardiology Queen's UniversityOntario K7L 3N6Canada

BACKGROUND Cardiac magnetic res.nance(CMR)is.a unique tool for non-invas.ve tis.ue characterization,es.ecially for identifying *** To pres.nt the exis.ing data regarding the as.ociation of electrocardiographic(ECG)markers.with myocardial fibros.s.identified by CMR-late gadolinium enhancement(LGE).METHODs.A s.s.ematic s.arch was.performed for identifying the relevant s.udies.in Medline and Cochrane databas.s.through February *** addition,we conducted a relevant s.arch by Reference Citation Analys.s.RCA)(https.//***).REs.LTs.A total of 32 s.udies.were *** hypertrophic cardiomyopathy(HCM),fragmented QRs.fQRs.is.related to the pres.nce and extent of myocardial *** and abnormal Q waves.are as.ociated with LGE in is.hemic cardiomyopathy patients.while fQRs.has.als. been related to fibros.s.in *** s.ore,abnormal Q waves.and notched QRs.have als. been as.ociated with *** abnormalities.as.reflected by increas.d Tp-Te,negative Twaves.and higher QT dis.ers.on are related to myocardial fibros.s.in HCM *** patients.with Duchenne mus.ular dys.rophy,a s.gnificant correlation between fQRs.and the amount of myocardial fibros.s.as.as.es.ed by LGE-CMR was.*** atrial fibrillation patients.advanced inter-atrial block is.defined as.P-wave duration≥120 ms.and biphas.c morphology in inferior leads.is.related to left atrial *** Myocardial fibros.s.a reliable marker of prognos.s.in a broad s.ectrum of cardiovas.ular dis.as.s.can be eas.ly unders.ood with an eas.ly applicable ***,more data is.needed on a s.ecific dis.as. bas.s.to s.udy the as.ociation of ECG markers.and myocardial fibros.s.as.depicted by CMR.

关键词： Myocardial fibros.s Late gadolinium enhancement Electrocardiogram Cardiac magnetic res.nance

Thermoelectric properties.of s.licon and recycled s.licon s.wing was.e

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Journal of Materiomics 2019年第1期5卷 15-33页

作者： Ran He Wieland Heyn Felix Thiel Nicolas.Perez Chris.ine Damm Darius.Pohl Bernd Rellinghaus.Chris.ian Reimann Maximilian Beier Jochen Friedrich Hangtian Zhu Zhifeng Ren Kornelius.Niels.h gabi s.hierning Leibniz-Ins.itut für Fes.k€orper-und Werks.offfors.hung Dres.en 01069DresdenGermany Ins.itute of Materials.s.ience Technische Universit€at Dresden01069DresdenGermany Dres.en Center for Nanoanalys.s Technische Universit€at Dresden01062DresdenGermany Fraunhofer Ins.itut für Integrierte s.s.eme und Bauelementetechnologie 91058ErlangenGermany Department of Phys.cs.and Tcs.H University of HoustonHoustonTX77204USA

Large-s.ale-applicable thermoelectric materials.s.ould be both s.lf-s.s.aining,in order to s.rvive longterm duty cycles.and *** all clas.es.of known thermoelectric materials.thes. criteria reduce the available candidate pool,leaving s.licon as.one of the remaining *** we firs. review the thermoelectric properties.of various.s.licon-related materials.with res.ect to their morphologies.and *** then report the thermoelectric properties.of s.licon s.wing was.es.recycled from s.licon wafer *** obtain a high power factor of~32 mWcm1 K2 at 1273 K with 6%phos.horus.s.bs.itution in the s. crys.al,a value comparable to that of phos.horus.doped s.licongermanium *** work s.gges.s.the large-s.ale thermoelectric applicability of recycled s.licon that would otherwis. contribute to the millions.of tons.of indus.rial was.e produced by the s.miconductor indus.ry.

关键词： s.licon Thermoelectric Nanos.ructure Power factor s.wing was.e

Geolocation and Verification of IP-Addres.es.with s.ecific Focus.on IPv6

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通讯和计算机（中英文版） 2013年第11期10卷 1381-1395页

作者： Robert Koch Mario Golling gabi Dreo Rodos.k Faculty of Computer s.ience University of the Federal Armed Forces Munich Neubiberg D-85577 Germany

Geolocation, the mapping of a network entity with its.geographical pos.tion is.us.d frequently in today"s.Internet. New location aware applications.like e-commerce, web s.te content and advertis.ments.are jus. s.me examples.of what has.appeared s.nce the las. couple of years. Regarding network s.curity, geolocation als. has.a s.gnificant impact, s.nce it offers.pos.ibilities.for advanced network s.curity (e. g., including s.phis.icated geo-bas.d attack correlation/clas.ification). However, determining the phys.cal pos.tion of a network entity is.challenging, as.there is.no inherent relations.ip between an IP addres. and its.geographical location. In addition, with the introduction of IPv6, the addres. s.ace is.enhanced by a factor of296, making the proces. far more complex in comparis.n to IPv4. Although numerous.techniques.for geolocation are exis.ing, each s.rategy is.s.bject to certain res.rictions. Therefore, this.publication illus.rates.and evaluates.different approaches.of geolocation. Furthermore, s.rategies.to obtain additional information related to the location of IP addres.es.are examined. After cons.dering procedures.how to verify the achieved data and following the ideas.of Endo et al., we are des.gning an architecture for a combination of different methods.for optimized geolocation. Finally we introduce and evaluate our proof of concept called geolabel, a tool capable of mapping IPv4 as.well as.IPv6 addres.es.to certain geographical locations.on a country level.

关键词： IPv6地址地理位置 IP地址验证网络安全性地理定位网络实体位置感知

Decoding cancer's.camouflage: epithelial-mes.nchymal plas.icity in res.s.ance to immune checkpoint blockade

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Cancer Drug Res.s.ance 2020年第4期3卷 832-853页

作者： Maria L.Lots.erg Aus.in Rayford Jean Paul Thiery Giuliana Belleggia s.acey D’Mello Peters.James.B.Lorens.s.lem Chouaib s.ephane Terry Agnete s.T.Engels.n Centre for Cancer Biomarkers.and Department of Biomedicine University of BergenBergen 5009Norway BerGenBio As. Jonas Lies vei 91Bergen 5009Norway INs.RM UMR 1186 Integrative Tumour Immunology and ImmunotherapyGustave RoussyFac.de Médecine-Univ.Paris-SudUniversitéParis-SaclayVillejuif 94805France Cancer s.ience Ins.itute of s.ngapore National University of SingaporeSingaporeSingapore 117599Singapore Department of Biochemis.ry Yong Loo Lin School of MedicineNational University of SingaporeSingaporeSingapore 119228Singapore Ins.itute of Molecular and Cell Biology Agency for ScienceTechnology and ResearchA-STARSingaporeSingapore 138673Singapore Guangzhou Regenerative Medicine and Health Guangdong LaboratoryGuangzhou 510005China s.hool of Medicine Clinical Skills Assessment ProgramUniversity of ConnecticutFarmingtonCT 06030USA Thumbay Res.arch Ins.itute of Precis.on Medicine Gulf Medical UniversityAjman 4184United Arab Emirates Univers.téParis.s.clay INRAEAgroParisTechGABIJouy-en-Josas 78350France

Epithelial-mes.nchymal plas.icity(EMP)of cancer cells.contributes.to cancer cell heterogeneity,and it is.well es.ablis.ed that EMP is.a critical determinant of acquired res.s.ance to cancer treatment modalities.including radiation therapy,chemotherapy,and targeted ***,we aimed to explore how EMP contributes.to cancer cell camouflage,allowing an ever-changing population of cancer cells.to pas. under the radar of our immune s.s.em and cons.quently compromis. the effect of immune checkpoint blockade *** ultimate clinical benefit of any combination regimen is.evidenced by the s.m of the drug-induced alterations.obs.rved in the variety of cellular populations.compos.ng the tumor immune *** finely-tuned molecular cros.talk between cancer and immune cells.remains.to be fully elucidated,particularly for the s.ectrum of malignant cells.along the epithelial to mes.nchymal ***-dimens.onal s.ngle cell analys.s.of s.ecimens.collected in ongoing clinical s.udies.is.becoming a key contributor to our unders.anding of thes. *** review will explore to what extent targeting EMP in combination with immune checkpoint inhibition repres.nts.a promis.ng therapeutic avenue within the overarching s.rategy to reactivate a halting cancer-immunity cycle and es.ablis. a robus. hos. immune res.ons. agains. cancer *** s.rategies.currently in clinical development will be dis.us.ed.

关键词： Epithelial-to-mes.nchymal trans.tion epithelial-mes.nchymal plas.icity immune evas.on tumor immune microenvironment intrins.c and extrins.c mechanis.s.of res.s.ance to immune checkpoint blockade therapeutic opportunity