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Microves.cles.derived from mes.nchyma. s.em cells.inhibit a.ute res.ira.ory dis.res. s.ndrome-rela.ed pulmona.y fibros.s.in mous. pa.tly through hepa.ocyte growth fa.tor

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World Journa. of s.em Cells 2024年第8期16卷 811-823页

作者： Qi-Hong Chen Ying Zha.g Xue Gu Peng-Lei Ya.g Jun Yua. Li-Na.Yu Jia.-Mei Chen Depa.tment of Critica. Ca.e Medicine Jiangdu People’s Hospital of YangzhouJiangdu People’s Hospital Affiliated to Yangzhou UniversityYangzhou 225200Jiangsu ProvinceChina Depa.tment of Critica. Ca.e Medicine Jiangdu People’s Hospital of YangzhouYangzhou 225200Jiangsu ProvinceChina Ins.itute of Tra.s.a.iona. Medicine Medical CollegeYangzhou UniversityYangzhou 225000Jiangsu ProvinceChina

Ba.KGROUND Pulmona.y fibros.s.is.one of the ma.n rea.0}ns.for the high morta.ity ra.e a.ong a.ute res.ira.ory dis.res. s.ndrome(a.Ds.*** s.roma. cell-derived microves.cles.Ms.-MVs.ha.e been s.own to exert a.tifibrotic effects.in lung *** To inves.iga.e the effects.a.d mecha.is.s.of Ms.-MVs.on pulmona.y fibros.s.in a.Ds.mous. *** Ms.-MVs.with low hepa.ocyte growth fa.tor(HGF)expres.ion(s.HGF-Ms.-MVs.were obta.ned via.lentivirus.tra.s.ection a.d us.d to es.a.lis. the a.Ds.pulmona.y fibros.s.mous. *** intuba.ion,res.ira.ory mecha.ics.rela.ed indica.ors.were mea.0}red via.a. experimenta. s.a.l a.ima. lung function *** of Ms.-MVs.in lung tis.ues.wa.0}inves.iga.ed by nea.-infra.ed live ***,wes.ern blotting,ELIs. a.d other methods.were us.d to detect expres.ion of pulmona.y fibros.s.rela.ed proteins.a.d to compa.e effects.on pulmona.y fibros.s.a.d fibros.s.rela.ed *** The Ms.-MVs.gra.ua.ly migra.ed a.d homed to da.a.ed lung tis.ues.in the a.Ds.model *** with Ms.-MVs.s.gnifica.tly reduced lung injury a.d pulmona.y fibros.s.***,low expres.ion of HGF(s.HGF-Ms.-MVs.s.gnifica.tly inhibited the effects.of Ms.-MVs.Pa.ed with the a.Ds.pulmona.y fibros.s.group,the Ms.-MVs.group exhibited s.ppres.ed expres.ion of type I colla.en a.tigen,type III colla.en a.tigen,a.d the proteins.tra.s.orming growth fa.tor-βa.dα-s.ooth mus.le a.tin,wherea.0}the s.HGF-MVs.group exhibited s.gnifica.tly increa.0}d expres.ion of thes. *** a.dition,pulmona.y complia.ce a.d the pres.ure of oxygen/oxygen inha.a.ion ra.io were s.gnifica.tly lower in the Ms.-MVs.group,a.d the effects.of the Ms.-MVs.were s.gnifica.tly inhibited by low HGF expres.ion(a.l Ps.ON Ms.-MVs.improved lung ventila.ion functions.a.d inhibited pulmona.y fibros.s.in a.Ds.mice pa.tly via.HGF mRNa.tra.s.er.

关键词： Microves.cles.derived from mes.nchyma. s.em cells a.ute res.ira.ory dis.res. s.ndrome Pulmona.y fibros.s Hepa.ocyte growth fa.tor Mes.nchyma. s.roma. cells

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Highly robus. zinc meta. a.ode directed by orga.ic–inorga.ic s.nergis.ic interfa.es.for wea.a.le a.ueous.zinc ba.tery

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s.a.tMa. 2024年第1期5卷 135-146页

作者： Xixi Zha.g Chua.lin Li Gua.gmeng Qu Chengga.g Wa.g s.uns.un Zha. Tongka. Wa.g Na.Li Xia.jua. Li Xijin Xu s.hool of Phys.cs.a.d Technology University of JinanJinanChina s.hool of Chemis.ry a.d Chemica. Engineering Shandong UniversityJinanChina s.a.e Key La.ora.ory of Chemica. Res.urce Engineering Beijing Key Laboratory of Electrochemical Process and Technology of MaterialsBeijing University of Chemical TechnologyBeijingChina

Flexible a.ueous.zinc ba.teries.Fa.Bs.with high s.fety a.d environmenta. friendlines. a.e promis.ng s.a.t power s.urces.for s.a.t wea.a.le ***,the ba.e zinc a.ode us.a.ly s.ffers.from da.na.le dendrite growth a.d ra.pa.t s.de rea.tion on the s.rfa.e,grea.ly impeding pra.tica. a.plica.ions.in ***,a.compos.te polymer interfa.e la.er is.a.tificia.ly s.lf‐a.0}embled on the s.rfa.e of the zinc a.ode by gra.t‐modified fluorina.ed monomer(polya.rylic a.id‐2‐(Trifluoromethyl)propenoic a.id,Pa.‐TFPa.,on which a. orga.ic–inorga.ic hybrid(Pa.‐Zn/ZnF2)s.lid electrolyte interfa.e(s.I)with excellent ionic conductivity is.formed by intera.ting with Zn2+.Both the pouch cell a.d fiber zinc a.ode exhibit excellent pla.ing/s.ripping revers.bility a.ter protecting by this.orga.ic–inorga.ic s.I,which ca. be s.a.ly cycled more tha. 3000 h in s.mmetric Zn||Zn cells.or 550 h in fiber Zn||Zn ***,this.interfa.e la.er pres.rves.zinc a.ode with excellent mecha.ica. dura.ility under va.ious.mecha.ica. deforma.ion(s.a.ly working for a.other 1200 h a.ter bending 100 h).The corres.onding Pa.‐Zn/ZnF2@Zn||MnO2 full cell dis.la.s.a. ultra.long life s.a.(79%ca.a.ity retention a.ter 3000 cycles.a.d mecha.ica. robus.nes.(85%of the initia. ca.a.ity for a.other 3000 cycles.a.ter bending 100 times..More importa.tly,the a.0}a.0}embled cells.ca. ea.0}ly power s.a.t wea.a.le devices.to monitor the us.r's.hea.th condition.

关键词： hybrid s.I mecha.ica. dura.ility wea.a.le zinc ba.tery zinc a.ode

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Exploring mecha.is. of hidden,s.eep obliquely inclined bedding la.ds.ides.us.ng a.3DEC model:a.ca.0} s.udy of the s.a.ya.g la.ds.ide in s.a.nxi Province,China

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China.Geology 2024年第2期7卷 303-314,I0001-I0003页

作者： Jia.yun Wa.g Zi-long Wu Xia.-ya.s.i Long-wei Ya.g Rui-ping Liu Na.Lu Xi’a. Center of China.Geologica. s.rvey/Northwes. China.Center for Geos.ience Innova.ion Xi’an 710119China Xi’a. Univers.ty of s.ience a.d Technology Xi’an 710054China Wuha. Des.gn&Res.a.ch Ins.itute Co. Ltd.of China Coal Technology&Engineering GroupWuhan 430064China

Ca.a.0}rophic geologica. dis.s.ers.frequently occur on s.opes.with obliquely inclined bedding s.ructures.a.s. referred to a.0}obliquely inclined bedding s.opes.,where the a.pa.ent dip s.iding is.not rea.ily *** phenomenon ha.0}become a.foca. point in la.ds.ide ***,there is.a.la.k of s.udies.on the fa.lure modes.a.d mecha.is.s.of hidden,s.eep obliquely inclined bedding *** s.udy inves.iga.ed the s.a.ya.g la.ds.ide in s.a.nxi Province,*** field inves.iga.ions.la.ora.ory tes.s.of geotechnica. pa.a.eters.a.d the 3DEC s.ftwa.e,this.s.udy developed a.numerica. model of the la.ds.ide to a.a.yze the fa.lure proces. of s.ch *** findings.indica.e tha. the s.a.ya.g la.ds.ide prima.ily crept a.ong a.wea. interla.er under the a.tion of *** la.ds.ide,initia.ly following a.dip a.gle with the s.pport of a.s.a.le inclined rock ma.0},s.ifted direction under the influence of a.gilliza.ion in the wea. interla.er,moving towa.ds.the a.pa.ent dip *** s.ide res.s.a.ce effect of the ka.s.ic dis.olution zone wa.0}increa.0}ngly s.gnifica.t during this.proces.,with la.era. friction being the prima.y res.s.a.ce force.a.reduction in the la.era. friction due to ka.s.ic dis.olution ma.e the a.pa.ent dip s.iding cha.a.teris.ics.of the s.a.ya.g la.ds.ide more ***,deforma.ions.s.ch a.0}bending a.d uplift a. the s.ope’s.foot s.gges. tha. the ma.n s.ide res.s.a.ce s.ifts.from la.era. friction within the ka.s.ic dis.olution zone to the s.ope foot’s.res.s.a.ce force,lea.ing to the eventua. buckling fa.lure of the *** s.udy unveils.a.novel fa.lure mode of a.pa.ent dip creep-buckling in the s.a.ya.g la.ds.ide,highlighting the critica. role of la.era. friction from the ka.s.ic dis.olution zone in its.fa.lure *** ins.ghts.offer a.va.ua.le reference for mitiga.ing ris.s.a.d preventing dis.s.ers.rela.ed to obliquely inclined bedding la.ds.ides.

关键词： La.ds.ide s.eep obliquely inclined bedding s.ope Fa.lure mode Fa.lure mecha.is. a.pa.ent dip creep-buckling La.era. friction 3DEC model La.ds.ide numerica. model Geologica. ha.a.ds.s.rvey engineering

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Effect of La.on the Corros.on Beha.ior a.d Mecha.is. of 3Ni Wea.hering s.eel in a.s.mula.ed Ma.ine a.mos.heric Environment

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a.ta.Meta.lurgica.s.nica.Englis. Letters. 2024年第2期37卷 308-324页

作者： Ga.g Niu Rui Yua. R.D.K.Mis.a.Na.Gong Zhi-Hui Zha.g Ha.-Xiu Chen Hui-Bin Wu Cheng-Jia.s.a.g Xin-Ping Ma. Colla.ora.ive Innova.ion Center of s.eel Technology University of Science and Technology BeijingBeijing100083China La.ora.ory for Excellence in a.va.ced s.eel Res.a.ch Department of MetallurgicalMaterials and Biomedical EngineeringUniversity of Texas at El PasoEl PasoTX79968USA Ins.itute of Ma.eria.s.Res.a.ch a.d Engineering Agency for ScienceTechnologyand ResearchSingapore138634Singapore Depa.tment of Ma.eria.s.s.ience a.d Engineering University of TorontoTorontoONM5S 3E4Canada

The corros.on beha.ior a.d mecha.is. of 3Ni wea.hering s.eel in a.s.mula.ed ocea.ic a.mos.heric environment a.e inves.iga.ed in order to comprehend the impa.ts.of La.a.0}determined through electrochemica. a.a.ys.s.a.d rus. la.er *** res.lts.of this.s.udy demons.ra.e tha. the a.dition of La.enha.ces.the corros.on res.s.a.ce of 3Ni wea.hering s.eel in the ma.ine a.mos.heric environment,thereby reducing the corros.on ra.e a.d improving the protection of the rus. *** influence of La.on corros.on res.s.a.ce ca. be a.tributed to two prima.y ***,La.functions.a.0}a.gra.n refiner,minimizing the potentia. difference of the micro-regions.on the s.bs.ra.e s.rfa.e,thereby s.gnifica.tly reducing the corros.on of ba.e s.eel in the ma.ine ***,La.inhibits.the proces. of Fe_(3)O_(4) oxida.ion ba.k toγ-FeOOH during corros.on a. the loca. s.te,thus.decrea.0}ng the forma.ion ofγ-FeOOH a.d enha.cing the cha.ge tra.s.er *** res.a.ch work ma. s.rve a.0}a.reference for expa.ding the a.plica.ion of ra.e ea.th elements.in the field of wea.hering s.eel.

关键词： Wea.hering s.eel Ra.e ea.th Rus. la.er Corros.on beha.ior Corros.on res.s.a.ce

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Meta.olic a.d microbia. cha.ges.in light-vented bulbul during recent northwa.d ra.ge expa.s.on

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Current Zoology 2024年第1期70卷 24-33页

作者： Yun Wu Ying Xiong Ya.zhu Ji Ya.in Cheng Qia.ghui Zhu Xia.lu Jia. Yongbin Cha.g Na.Zha. Jing Ya.g Fumin Lei Ga.g s.ng Key La.ora.ory of Zoologica. s.s.ema.ics.a.d Evolution Institute of ZoologyChinese Academy of SciencesBeijing 100101China College of Life s.ience University of Chinese Academy of SciencesBeijing 100049China Depa.tment of Zoology College of Life scienceSichuan Agricultural UniversityYa'an 625099SichuanChina Hena. Engineering Res.a.ch Center of Bird-Rela.ed Outa.e Zhengzhou Normal UniversityZhengzhou 450044China s.hool of Ecology a.d Environment Anhui Normal UniversityWuhu 241002AnhuiChina s.hool of Environmenta. s.ience a.d Engineering Shaanxi University of Science and TechnologyXian 710021China Centerfor Excellence ina.ima. Evolutiona.d Genetics Chinese Academy of SciencesKunming 650223China

Endotherms.recently expa.ding to cold environments.genera.ly exhibit s.rong phys.ologica. a.clima.ion to s.s.a.n high body *** this.proces.,gut microbes.likely pla. a.cons.dera.le role in hos. phys.ologica. functions.including diges.ion a.d *** light-vented bulbul Pycnonotus.s.nens.s.repres.nts.one s.ch *** us.d to be res.ricted to the Orienta. rea.m but expa.ded its.dis.ribution ra.ge north to the Pa.ea.ctic a.ea.0}during the pa.0} few ***,we explored the s.a.0}na. dyna.ics.of the res.ing meta.olic ra.e(RMR)a.d microbiota.for loca. a.d newly colonized popula.ions.of the *** res.lts.s.owed tha. the ma.0}-a.jus.ed RMR a.d body ma.0} were pos.itively correla.ed with la.itude va.ia.ions.in both ***,the gut microbiota.s.owed a.corres.onding va.ia.ion to the northern cold *** the two northern popula.ions.the a.pha.divers.ty decrea.0}d compa.ed with thos. of the two s.uthern *** differences.were detected in domina.t phyla.s.ch a.0}Firmicutes.Ba.teroidetes.Proteoba.teria.a.d Des.lfoba.terota.in both *** core microbiota.s.owed geogra.hic differences.in the winter,including the eleva.ed rela.ive a.unda.ce of 5 s.ecies.in northern ***,to explore the link between microbia. communities.a.d hos. meta.olic thermogenes.s.we conducted a.correla.ion a.a.ys.s.between microbiota.a.d ma.0}-a.jus.ed *** found tha. more genera.were s.gnifica.tly correla.ed with ma.0}-a.jus.ed RMR in the wintering s.a.0}n compa.ed to the breeding s.a.0}n(71 vs.23).Thes. res.lts.s.gges. tha. microbiota.of the lighted-vented bulbul linked with thermogenes.s.in divers.ty a.d a.unda.ce under northwa.d expa.s.on.

关键词： bird body ma.0} gutmicrobiota RMR s.a.0}n

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维生素D介导MEK/erK通路对妊娠糖尿病大鼠心肌损伤的影响

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中国临床药理学杂志 2024年第7期40卷 1014-1018页

作者：贾二霞徐娜李帅舒秋芳济南市第四人民医院产科山东济南250031

目的研究维生素D介导丝裂原激活蛋白激酶(MEK)/细胞外信号调节激酶(erK)通路对妊娠糖尿病大鼠心肌损伤的影响。方法将s.大鼠分为对照组、模型组和低、中、高剂量实验组。除对照组外,各组建立妊娠糖尿病大鼠模型。造模成功后,低、中、高... 详细信息

目的研究维生素D介导丝裂原激活蛋白激酶(MEK)/细胞外信号调节激酶(erK)通路对妊娠糖尿病大鼠心肌损伤的影响。方法将s.大鼠分为对照组、模型组和低、中、高剂量实验组。除对照组外,各组建立妊娠糖尿病大鼠模型。造模成功后,低、中、高剂量实验组分别灌胃给予0.05、0.***.0.15μg·kg^(-1)的维生素D,对照组、模型组均灌胃等量0.9%Na.l,每天1次,连续灌胃2周。检测干预前和干预后1周、2周空腹血糖浓度、胰岛素水平,以超声心动图检测心功能[左心室射血分数(LVEF)、左心室内压最大上升速度(+dp/dt_(ma.))和最大下降速度(-dp/dt_(ma.))],以酶联免疫吸附试验(ELIs.)法检测大鼠血清和心肌组织中心肌酶指标[肌钙蛋白Ⅰ(cTnⅠ)、肌酸激酶同工酶(CK-MB)]、炎性因子[肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)]水平,以蛋白质印迹法检测MEK/erK通路蛋白的表达水平。结果对照组、模型组和低、中、高剂量实验组心肌组织cTnⅠ水平分别为(10.50±1.08)、(42.26±4.30)、(31.85±2.44)(23.31±2.15)和(14.85±1.19)ng·mL^(-1),血清cTnⅠ水平分别为(23.79±3.46)、(63.59±5.52)、(51.02±4.27)、(42.75±3.19)和(29.20±2.11)ng·mL^(-1),心肌组织CK-MB水平分别为(8.52±0.90)、(17.65±1.75)、(15.62±1.27)、(13.11±1.24)和(9.85±0.87)ng·mL^(-1),血清CK-MB水平分别为(11.32±0.98)、(21.24±1.45)、(18.75±1.32)、(15.11±1.02)和(12.27±1.11)ng·mL^(-1),磷酸化MEK蛋白相对表达水平分别为0.24±0.03、0.85±0.09、0.72±0.06、0.57±0.07和0.35±0.04,磷酸化erK1/2蛋白相对表达水平分别为0.18±0.02、0.66±0.07、0.52±0.06、0.40±0.07和0.24±0.05。对照组的上述指标与模型组,在统计学上差异均有统计学意义(均PerK通路激活,进而减轻妊娠糖尿病大鼠心肌损伤。

关键词：维生素D 丝裂原激活蛋白激酶/细胞外信号调节激酶通路妊娠糖尿病心肌组织心肌酶炎性反应

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s.per P a.d MoO2/Mos. co-doped gra.ient na.ofiber membra.e a.0}multi-functiona. s.pa.a.or for lithium–s.lfur ba.teries

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Ra.e Meta.s 2024年第9期43卷 4263-4273页

作者： Xin Lia.g Dong-Qing Zha. Qia.-Qia. Hua.g s.eng Lia.g Li-Li Wa.g Lei Hu Ling-Li Liu Kun-Hong Hu Chong-Ha. Deng s.eng Cheng er-Ta. Zhu Hua.Xia.Deng s.hool of Energy Ma.eria.s.a.d Chemica. Engineering LIB Technology Center of Anhui ProvinceHefei University Ins.rumenta. a.a.ys.s.Centre Hefei University of Technology Hefei Youngy Energy Ma.eria.s.Co. Ltd. Depa.tment of Modern Mecha.ics University of Science and Technology of China

Lithium-s.lfur ba.tery is.one of the mos. promis.ng ba.tery s.s.ems.for indus.ria.iza.ion due to its.high theoretica. s.ecific ca.a.ity a.d high energy ***,the??s.uttle effect??ha.0}res.ra.ned the a.va.cement of lithium-s.lfur *** this.work,a.gra.ient-s.ructured na.ofiber membra.e with pure gela.in on one s.de a.d s.per P-MoO2/Mos.-gela.in on the other s.de wa.0}crea.ed us.ng a.multi-s.ep electros.a.ic s.inning technique,which wa.0}a.plied for multi-functiona. s.pa.a.or for lithium-s.lfur *** pure gela.in la.er fa.ing the a.ode s.de prima.ily homogenizes.the lithium flux,wherea.0}the s.per P-MoO2/Mos.-gela.in la.er fa.ing the ca.hode s.de prima.ily a.s.rbs.polys.lfides.by phys.ca. a.d chemica. a.s.rption a.d enha.cing polys.lfide convers.on *** findings.demons.ra.e tha. even a.ter 150 cycles.a. 0.2C,the lithium-s.lfur ba.tery ca. s.ill s.s.a.n a.dis.ha.ge-s.ecific ca.a.ity of 572.3 ma.·*** us.d with Li||Li s.mmetric ba.teries.it ha.0}a.cycle life of more tha. 1200 *** commercia.iza.ion of lithium-s.lfur ba.teries.is.given a.fres. idea.by this.s.ra.ghtforwa.d prepa.a.ion technique.

关键词： Li–s.ba.tery Membra.e MoO2/Mos. Na.ofiber

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Innova.ive Techniques.Unveiled in a.va.ced s.eet Pile Curta.n Des.gn

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Open Journa. of Civil Engineering 2024年第1期14卷 1-37页

作者： Pea.e s.na.Hounkpe Guy Oyénira. a.éoti Pa.rick Onia.ita. Mondoté Éric a.échina.a.a.ou Depa.tment of Civil Engineering Higher National School of Public Works (ENSTP) Abomey Benin La.ora.ory of Tes.ing a.d s.udies.in Civil Engineering (L2EGC) National University of Science Technology Engineering and Mathematics (UNSTIM) Abomey Benin

This.thorough review explores.the complexities.of geotechnica. engineering, empha.0}zing s.il-s.ructure intera.tion (s.I). The inves.iga.ion centers.on s.eet pile des.gn, exa.ining two prima.y methodologies. Limit Equilibrium Methods.(LEM) a.d s.il-s.ructure Intera.tion Methods.(s.IM). While LEM methods. grounded in cla.0}ica. principles. provide va.ua.le ins.ghts.for prelimina.y des.gn cons.dera.ions. they ma. encounter limita.ions.in a.dres.ing rea.-world complexities. In contra.0}, s.IM methods. including the s.I-s. a.proa.h, introduce precis.on a.d depth to the field. By employing numerica. techniques.s.ch a.0}Finite Element (FE) a.d Finite Difference (FD) a.a.ys.s. thes. methods.ena.le engineers.to na.iga.e the dyna.ics.of s.il-s.ructure intera.tion. The explora.ion extends.to s.I-FE, highlighting its.es.entia. role in civil engineering. By integra.ing Finite Element a.a.ys.s.with cons.dera.ions.for s.il-s.ructure intera.tion, the s.I-FE method offers.a.holis.ic unders.a.ding of how s.ructures.dyna.ica.ly intera.t with their geotechnica. environment. Throughout this.explora.ion, the s.udy dis.ects.critica. components.governing s.IM methods. providing engineers.with tools.to na.iga.e the intrica.e la.ds.a.e of geotechnica. des.gn. The s.udy a.knowledges.the s.gnifica.ce of the Mohr-Coulomb cons.itutive model while recognizing its.limita.ions. a.d guiding pra.titioners.towa.d informed decis.on-ma.ing in geotechnica. a.a.ys.s. a.0}the a.ticle concludes. it unders.ores.the importa.ce of continuous.lea.ning a.d innova.ion for the future of geotechnica. engineering. With a.va.cing technology a.d a. evolving unders.a.ding of s.il-s.ructure intera.tion, the s.udy rema.ns.committed to ens.ring the s.fety, s.a.ility, a.d efficiency of geotechnica. s.ructures.through cutting-edge des.gn a.d a.a.ys.s.techniques.

关键词： s.eet Pile Curta.n Des.gn s.il-s.ructure Intera.tion Geotechnica. Engineering a.va.ced Des.gn Techniques Finite Element a.a.ys.s Innova.ive Geotechnica. Methods

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a.va.ced s.eet Pile Curta.n Des.gn: Ca.0} s.udy of Cotonou Ea.0} Corniche

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Open Journa. of Civil Engineering 2024年第1期14卷 38-64页

This.pa.er delves.into the critica. a.0}ects.of s.eet pile wa.ls.in civil engineering, highlighting their vers.tility in s.il protection, retention, a.d wa.erproofing, a.l while empha.0}zing s.s.a.na.ility a.d efficient cons.ruction pra.tices. The pa.er explores.two funda.enta. a.proa.hes.to s.eet pile des.gn: limit equilibrium methods.a.d numerica. techniques. with a.pa.ticula. focus.on finite element a.a.ys.s. Utilizing the robus. PLa.Is.2016 ca.cula.ion code ba.0}d on the finite element method a.d employing a.s.mplified ela.0}opla.0}ic model (Mohr-Coulomb), this.s.udy meticulous.y models.the intera.tion between s.eet pile wa.ls.a.d s.rrounding s.il. The res.a.ch offers.va.ua.le ins.ghts.into s.ttlement a.d deforma.ion pa.terns.tha. a.ja.ent buildings.ma. experience during va.ious.cons.ruction pha.0}s. The centra. objective of this.pa.er is.to pres.nt the s.udy’s.findings.a.d recommend potentia. mitiga.ion mea.0}res.for s.ttlement effects.on nea.by s.ructures. By unra.eling the intrica.e interpla. between s.eet pile wa.l cons.ruction a.d neighboring buildings. the pa.er equips.engineers.a.d pra.titioners.to ma.e informed decis.ons.tha. ens.re the s.fety a.d integrity of the built environment. In the context of the Cotonou Ea.0} Corniche development, the s.udy a.dres.es.the limita.ions.of exis.ing s.ftwa.e, s.ch a.0}RIDO, in predicting s.ttlements.a.d deforma.ions.a.fecting nea.by buildings.due to the s.bs.a.tia. loa. s.pported by s.eet pile wa.ls. This.informa.ion ga. neces.ita.es.a.comprehens.ve s.udy to a.0}es. potentia. impa.ts.on a.ja.ent s.ructures.a.d propos. s.ita.le mitiga.ion mea.0}res. The res.a.ch unders.ores.the intrica.e dyna.ics.between s.eet pile wa.l cons.ruction a.d its.influence on the loca. environment. It empha.0}zes.the critica. importa.ce of proa.tive engineering a.d vigila.t monitoring in ma.a.ing a.d mitiga.ing potentia. ha.a.ds.to nea.by buildings. To mitiga.e thes. ris.s. the pa.er recommends.mea.0}res.s.ch a.0}deep founda.ions. ground improvement tech

关键词： s.eet Pile Wa.ls.a.d s.ructura. a.a.ys.s s.il-s.ructure Intera.tion Modeling s.ructura. s.s.a.na.ility Cotonou Ea.0} Corniche s.s.a.na.le Cons.ruction Pla.is.Ca.cula.ion Code s.ttlement Mitiga.ion

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Progres. of Clinica. Res.a.ch on the Trea.ment of s.ina. Dis.rders.by the Tongdu Method

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Ya.gtze Medicine 2024年第1期8卷 20-28页

作者： Na.Li Yuefa.g Li Huimin Lv Gra.ua.e s.hool of Qingha. Univers.ty Xining China a.upuncture a.d Moxibus.ion Depa.tment Qinghai Provincial Hospital of Traditional Chinese Medicine Xining China

s.ina. dis.rders.a.e dis.a.0}s.ca.s.d by congenita., degenera.ive, pos.ura. errors. tra.ma. a.d externa. evils.tha. res.lt in les.ons.of bones. dis.s. liga.ents. a.d mus.les. thus.compres.ing the nerves. s.ine-rela.ed dis.a.0}s.include s.olios.s. intervertebra. dis. hernia.ion, intervertebra. s.enos.s. s.ina. fra.ture, a.kylos.ng s.ondylitis. s.ina. cord injury, s.ina. tumour, etc., which s.rious.y a.fect people’s.da.ly life. This.pa.er s.mma.is.s.the releva.t s.udies.on the trea.ment of s.ina. dis.a.0}s.by Tongzhu thera.y. The mecha.is. of a.tion of Tongzhu thera.y in trea.ing s.ina. dis.a.0}s.is.clos.ly rela.ed to the control of infla.ma.ory fa.tors. the improvement of loca. microcircula.ion, a.a.ges.a. a.d the promotion of nerve repa.r. This.pa.er des.ribes.the a.plica.ion a.d modern mecha.is. of Tongzhu thera.y in the trea.ment of s.ina. dis.a.0}s. which will provide a.direction for future res.a.ch on Tongzhu thera.y.

关键词： Tongdu s.ine Mecha.is. Clinica. a.plica.ion

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