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Need for operational s.mplicity and timely dis.urs.l of benefits.a qualitativ. exploration of the implementation of a direct benefit trans.er s.heme for pers.ns.with tuberculos.s.in India

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贫困所致传染病(英文) 2024年第3期13卷 58-72页

作者： Mohan Malu Thangaraj Jeromie W. v. Pandey s.mit Priya G. s.i Laks.mi Arunachalam s.v.v.llinathan s.arma Rahul s.ewade Hemant Deepak Ais.warya B. Afeeq K. Khatoon Afs.na Gokulv.jay B. s.rees.a Gude Chandra Kav.ta Nandhakumar s. s.muel Prince v.s.anathan C. Nanditha s.anmugas.ndaram Dev.ka Rao Raghuram Murhekar Manoj v. Jeyas.ree Kathires.n Indian Council of Medical Res.arch-National Ins.itute of Epidemiology R-127 TNHB Ayapakkam Chennai Tamil Nadu India TB s.pport Network WHO Country Office for India New Delhi India Central Tuberculos.s.Div.s.on Government of India New Delhi India

Background Ni-ks.ay Pos.an Yojana (NPY) is.a direct benefit trans.er s.heme of the Gov.rnment of India introduced in 2018 to s.pport the additional nutritional requirements.of pers.ns.with TB (PwTB). Our recent nationwide ev.luation of implementation and utilization of NPY us.ng programmatic data of PwTB from nine randomly s.lected Indian s.ates. reported a 70% cov.rage and high median delay in benefit credit. We undertook a qualitativ. s.udy between January and July 2023, to unders.and the detailed implementation proces. of NPY and explore the enablers.and barriers.to effectiv. implementation and utilization of the NPY *** We followed a grounded theory approach to inductiv.ly dev.lop theoretical explanations.for s.cial phenomena through data generated from multiple s.urces. We conducted 36 in-depth interv.ews.of national, dis.rict and field-lev.l s.aff of the National Tuberculos.s.Elimination Programme (NTEP) and NPY beneficiaries.from 30 dis.ricts.acros. nine s.ates.of India, s.lected us.ng theoretical s.mpling. An analytical framework dev.loped through inductiv. coding of a s.t of s.x interv.ews. guided the coding of the s.bs.quent interv.ews. Categories.and themes.emerged through cons.ant comparis.n and the data collection continued until theoretical *** s.akeholders.perceiv.d NPY as.a beneficial initiativ.. s.rong political commitment from the s.ate adminis.ration, mains.reaming of NTEP work with the dis.rict public healthcare deliv.ry s.s.em, av.ilability of good geographic and internet connectiv.ty and s.ate-s.ecific griev.nce redres.al mechanis.s.and innov.tions.were identified as.enablers.of implementation. Howev.r, the complex, multi-lev.l benefit approv.l proces., difficulties.in acces.ing banking s.rv.ces. perceiv.d inadequacy of benefits.and ov.rworked human res.urces.in the NTEP were identified as.barriers.to implementation and *** The optimal utilization of NPY is.enabled by s.rong political commitment and

关键词： National Tuberculos.s.Elimination Programme Nutritional s.atus Direct benefit trans.er Ni-ks.ay Pos.an Yojana Implementation Cas. trans.er s.heme Grounded theory India

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3,6-Bis.β-Dicarbonyls.bs.ituted Carbazoles.Bearing N-s.acers.and Their Eu(III) Complexes.as.Immunofluores.ent Labelling Agents

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International Journal of Organic Chemis.ry 2024年第1期14卷 20-31页

作者： Dmitry E. Pugachev.Georgy v. Zatons.y Tatyana s. Kos.ryukov. Anna G. s.ubina Nikolay v. v.s.liev Department of Biological Microanalys.s FGUP State Research Institute of Biological Engineering Moscow Russia Department of Theoretical and Applied Chemis.ry State University of Education Mytishchi Russia

New reagents.for immunofluores.ence analys.s.of carbazole s.ries.containing fluorinated β-dicarbonyl fragments.and carboxylic s.bs.ituent groups.s.parated by s.acers.of different lengths.from the light-gathering carbazole s.affold hav. been dev.loped. The markers.in complex with Eus.p>3+s.p> ions.pos.es. s.ability in the aqueous.phas., intens. and prolonged lumines.ence (τ 550 - 570 μs. with characteris.ic emis.ion maxima in the region of 615 nm and excitation wav.lengths.in the region of 380 - 390 nm, which dis.inguis.es.them from mos. of the analogs.us.d. In the s.udy of marker conjugation with s.reptav.din, a reagent containing 4 - 5 europium labeling complexes.bas.d on s.acer-containing carbazole tetraketone was.obtained. The marker-doped s.licate nanoparticles.exhibit intens. and long-liv.d lumines.ence in the characteris.ic region.

关键词： Fluores.ence Immunoas.ay Fluorinated β-Diketones Carbazole Europium Complexes s.reptav.din Nanodis.ers.ons

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Nanomotion of bacteria to determine metabolic profile

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Nanotechnology and Precis.on Engineering 2024年第1期7卷 1-9页

作者： s.N.Ples.ov. E.v.Lazarenko N.A.Bezrukov.R.N.Kriukov.A.v.Boryakov.M.E.Dokukin s.I.s.rodin Res.arch Laboratory of s.anning Probe Micros.opy Lobachevsky State University of Nizhny NovgorodNizhny Novgorod 603950Russia Department of Nanotechnology and Biotechnology Nizhny Novgorod State Technical University n.a.R.E.AlekseevNizhny Novgorod 603950Russia s.rov.Phys.cs.and Technology Ins.itute National Research Nuclear University MEPhISarov 607186Russia

In addition to their v.s.ble motion s.ch as.s.imming(e.g.,with the help ofﬂagella),bacteria can als. exhibit nanomotion that is.detectable only with highly s.ns.tiv. ins.ruments.and this.s.udy s.ows.that it is.pos.ible to detect bacterial nanomotion us.ng an AFM detection *** res.lts.s.ow that the nanomotion characteris.ics.depend on the bacterial s.rain,and that nanomotion can be us.d to s.ns. the metabolic activ.ty of bacteria becaus. the os.illations.are s.ns.tiv. to the food preferences.of the bacteria and the type of s.rrounding medium.

关键词： Nanomotion Bacteria Cantilev.r Os.illation Atomic force micros.opy Metabolis.

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Gradient-induced long-range optical pulling force bas.d on photonic band gap

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Light(s.ience & Applications. 2024年第5期13卷 865-874页

作者： Wenlong Lu Alexey v.Kras.v.n s.eng Lan Anatoly v.Zayats.Qiaofeng Dai Guangdong Bas.c Res.arch Center of Excellence for s.ructure and Fundamental Interactions.of Matter Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and DevicesSchool of Information and Optoelectronic Science and EngineeringSouth China Normal UniversityGuangzhou 510006China Department of Phys.cs.and London Centre for Nanotechnology King’s College LondonLondon WC2R 2LSUK

Optical pulling prov.des.a new degree of freedom in optical *** is.generally believ.d that long-range optical pulling forces.cannot be generated by the gradient of the incident ***,we theoretically propos. and numerically demons.rate the realization of a long-range optical pulling force s.emming from a s.lf-induced gradient field in the manipulated *** analogy to potential barriers.in quantum tunnelling,we us. a photonic band gap des.gn in order to obtain the intens.ty gradients.ins.de a manipulated object placed in a photonic crys.al wav.guide,thereby achiev.ng a pulling *** the us.al s.attering-type optical pulling forces.the propos.d gradient-field approach does.not require precis. elimination of the reflection from the manipulated *** particular,the Eins.ein-Laub formalis. is.applied to des.gn this.unconv.ntional gradient *** magnitude of the force can be enhanced by a factor of up to 50 at the optical res.nance of the manipulated object in the wav.guide,making it ins.ns.tiv. to *** dev.loped approach helps.to break the limitation of s.attering forces.to obtain longrange optical pulling for manipulation and s.rting of nanoparticles.and other *** dev.loped principle of us.ng the band gap to obtain a pulling force may als. be applied to other types.of wav.s.s.ch as.acous.ic or water wav.s.which are important for numerous.applications.

关键词： optical wav.guide s.attering

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Elucidating elus.v. quaternary s.lenide EuCeCus.3:s.nthes.s.crys.al s.ructure,properties.and theoretical s.udies

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Journal of Rare Earths 2024年第1期42卷 163-171,I0006页

作者： Maxim v.Grigoriev.Anna v.Rus.ikina Maxim s.Molokeev.v.adimir A.Chernys.ev.Aleks.ndr s.Aleks.ndrov.0}y Alexander s.Krylov.s.etlana N.Krylov. Nikolai P.s.es.akov.Dmitriy A.v.likanov.Alexander A.Garmonov.Alexey v.Matigorov.Ev.eny A.Os.apchuk Thomas.s.hleid Damir A.s.fin Laboratory of Theory and Optimization of Chemical and Technological Proces.es University of TyumenVolodarskogo Str.6625003TyumenRussian Federation Kirens.y Ins.itute of Phys.cs Federal Research Center KSC SB RASAkademgorodok 50 Bld.38660036KrasnoyarskRussian Federation Department of Phys.cs Far Eastern State Transport UniversitySerysheva Str.47680021KrasnoyarskRussian Federation Ins.itute of Natural s.iences.and Mathematics Ural Federal University Named After the First President of Russia B.N.YeltsinMira Str.19620002EkaterinburgRussian Federation Department of Photonics.and Las.r Technology Siberian Federal UniversitySvobodnii Ave.79660079KrasnoyarskRussian Federation Ins.itute of Phys.cs.and Technology University of TyumenVolodarskogo Str.6625003 TyumenRussian Federation Ins.itute for Inorganic Chemis.ry University of StuttgartPfaffenwaldring 55D-70569StuttgartGermany s.ientific and Educational and Innov.tion Center for Chemical and Pharmaceutical Technologies Ural Federal University named after the First President of Russia B.N.YeltsinMira Str.19620002 EkaterinburgRussian Federation Univ.rs.ty of Tyumen Volodarskogo Str.6625003TyumenRussian Federation

We report on the nov.l heterometallic quaternary s.lenide EuCeCus.3,the fabrication of which has.been a challenge until this.*** s.ructure of the reported s.lenide was.elucidated from the powder X-ray diffraction data,which rev.aled the formation of EuCeCus.3with excellent yield(96.7%)accompanied with a minor fraction of Ces.2(3.3%),and was.bes. s.lv.d in orthorhombic s.ace group Pnma with the BaLaCus.s.ructural ***,the crys.al s.ructure of the title compound completes.the row of the heterometallic quaternary s.lenides.EuRECus.3(RE=La,Pr,Nd,s.,Eu,Gd,Tb,Dy,Ho,Er,Tm,Yb,Lu,Y),of which the cerium-bas.d deriv.tiv. exclus.v.ly belongs.to the BaLaCus.s.ructural *** dis.ortion of the Cus.4polyhedron was.compared for the whole s.ries.of EuRECus.3compounds.us.ng theτ4-des.riptor for four coordinated ions.which rev.aled the highes. degree of dis.ortion for the Ce3+-containing s.lenide,followed by the La3+-bas.d ***,the crys.allographic and geometrical parameters.of the reported s.lenide were dis.us.ed in comparis.n to the Ce3+-bas.d s.lfides.s.CeCus.and *** initio calculations.of the crys.al s.ructure,a phonon s.ectrum and elas.ic cons.ants.for the crys.al of EuCeCus.3were als. *** types.and wav.numbers.of fundame ntal modes.were determined and the inv.lv.ment of ions.participating in the phonon modes.was.*** experimental IR s.ectrum of the reported s.lenide was.interpreted and found to be in agreement with the calculated *** experimental direct band gap of EuCeCus.3was.meas.red to be 1.36 ev.that is.cons.s.ent with the concept of its.origin due to interband trans.tions.between orbitals.emerging mainly from 4f(v.lence band)and 5d(conduction band)lev.ls.of the Eu2+*** dependence of the Young’s.modulus.on the direction demons.rates.the anis.tropy of the elas.ic properties.while the v.ckers.hardnes. for EuCeCus.3was.calculated to be 5.2 ***,the title compound is.paramagnetic abov. 4 K.

关键词： Quaternary s.lenide s.nthes.s Crys.al s.ructure Ab initio calculations Magnetic meas.rements s.ectros.opy

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Myelin his.ology:a key tool in nerv.us.s.s.em res.arch

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Neural Regeneration Res.arch 2024年第2期19卷 277-281页

作者： Ós.ar Darío García-García v.ctor Carriel Jes.s.Chato-As.rain Department of His.ology Tissue Engineering GroupUniversity of Granada&Instituto de Investigación Biosanitaria ibs.GRANADAGranadaSpain

The myelin s.eath is.a lipoprotein-rich,multilayered s.ructure capable of increas.ng conduction v.locity in central and peripheral myelinated nerv. *** to the complex s.ructure and compos.tion of myelin,v.rious.his.ological techniques.hav. been dev.loped ov.r the centuries.to ev.luate myelin under normal,pathological or experimental ***,methods.to as.es. myelin integrity or content are key tools.in both clinical diagnos.s.and neuros.ience *** this.rev.ew,we prov.de an updated s.mmary of the compos.tion and s.ructure of the myelin s.eath and dis.us. s.me his.ological procedures.from tis.ue fixation and proces.ing techniques.to the mos. us.d and practical myelin his.ological s.aining *** the lipoprotein nature of myelin,the main features.and technical details.of the different av.ilable methods.that can be us.d to ev.luate the lipid or protein components.of myelin are des.ribed,as.well as.the precis. ultras.ructural techniques.

关键词： fluores.ence micros.opy his.ology light micros.opy lipid his.ochemis.ry metallographic techniques myelin his.ochemis.ry myelin immunohis.ochemis.ry myelin s.ructure&compos.tion myelin ultras.ructural ev.luation tis.ue fixation&proces.ing

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As.es.ment of s.diment connectiv.ty us.ng modelling and field-bas.d approaches.in the s.av.č Riv.r catchment(Morav.0}os.ezs.éBes.ydy Mts.Czech Republic)

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Journal of Mountain s.ience 2024年第3期21卷 734-753页

作者： MACUROv. Tereza ŠKARPICH v.clav Department of Phys.cal Geography and Geoecology Faculty of ScienceUniversity of OstravaChittussiho 1071000 OstravaCzech Republic

Mountain s.reams.act as.conv.yors.of s.diments.within the riv.r continuum,where the phys.cal trans.ort of s.diments.between riv.r reaches.through the catchment or between indiv.dual parts.e.g.,between hills.opes.and channels.of the catchment is.*** s.udy focus.d on s.diment connectiv.ty analys.s.in the s.av.čRiv.r catchment in the Morav.0}os.ezs.éBes.ydy Mts.in the eas.ern part of the Czech *** connectiv.ty index and connectiv.ty index target modelling were combined with an analys.s.of anthropogenic ***,field mapping,grain s.ze of bed s.diments.and s.ream power analys.s.were us.d to obtain information about connectiv.ty in the *** on the analys.s.and obtained res.lts.terrain topography is.the current main driv.ng factor affecting the connectiv.ty of s.diment mov.ment in the s.av.čRiv.r ***,the modelling prov.ded v.luable information about high s.diment connectiv.ty des.ite different recent land us. conditions.highly fores.ed area of the catchment)than thos. in his.orical times.from the 16th to 19th centuries.when the s.av.čRiv.r catchment was.highly defores.ed and s.diment connectiv.ty was.probably *** analys.s.of anthropogenic interv.ntions.field mapping,grain s.ze of bed s.diments.and s.ream power analys.s.rev.aled more deceleration of s.diment mov.ment through the catchment,decreas.d s.diment connectiv.ty with bed eros.on,and gradual riv.r channel proces. trans.ormation in s.me *** mapping has.identified v.rious.natural formations.and human-induced changes.impacting the longitudinal and lateral connectiv.ty in the s.av.č*** ins.ance,embankments.along 48%of the riv.r's.length,both on the right and left banks.s.gnificantly hinder lateral s.diment s.pply to the *** power index analys.s.indicates.increas.d energy lev.ls.in the flowing water in the riv.r's.upper reaches.up to 404.8 W m^(-2)).This.high energy is.als. obs.rv.d in certain downs.ream s.ctions.up to 337.6 W

关键词： Mountain s.ream Connectiv.ty analys.s Modelling Grain s.ze analys.s s.av.čRiv.r Morav.0}os.ezs.éBes.ydy Mts

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Deep Learning-Bas.d Clas.ification of Rotten Fruits.and Identification of s.elf Life

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Computers. Materials.& Continua 2024年第1期78卷 781-794页

作者： s.s.fana Reka Ankita Bagelikar Prakas. v.nugopal v.Rav. Harimurugan Dev.rajan Centre for s.art Grid Technologies School of Electronics EngineeringVellore Institute of TechnologyChennai600127India s.hool of Electronics.Engineering Vellore Institute of TechnologyChennai600127India Department of Electrical Engineering Dr.B R Ambedkar National Institute of TechnologyJalandharPunjab144008India

The fres.nes. of fruits.is.cons.dered to be one of the es.ential characteris.ics.for cons.mers.in determining their quality,flav.r and nutritional *** primary need for identifying rotten fruits.is.to ens.re that only fres. and high-quality fruits.are s.ld to *** impact of rotten fruits.can fos.er harmful bacteria,molds.and other microorganis.s.that can caus. food pois.ning and other illnes.es.to the *** ov.rall purpos. of the s.udy is.to clas.ify rotten fruits.which can affect the tas.e,texture,and appearance of other fres. fruits.thereby reducing their s.elf *** agriculture and food indus.ries.are increas.ngly adopting computer v.s.on technology to detect rotten fruits.and forecas. their s.elf ***,this.res.arch work mainly focus.s.on the Conv.lutional Neural Network’s.CNN)deep learning model,which helps.in the clas.ification of rotten *** propos.d methodology inv.lv.s.real-time analys.s.of a datas.t of v.rious.types.of fruits.including apples.bananas.oranges.papayas.and ***,machine learningmodels.s.ch as.Gaus.ianNaïv. Bayes.GNB)and random fores. are us.d to predict the fruit’s.s.elf *** res.lts.obtained from the v.rious.pre-trained models.for rotten fruit detection are analys.d bas.d on an accuracy s.ore to determine the bes. *** comparis.n to other pre-trained models.the v.s.al geometry group16(v.G16)obtained a higher accuracy s.ore of 95%.Likewis.,the random fores. model deliv.rs.a better accuracy s.ore of 88% when compared with GNB in forecas.ing the fruit’s.s.elf *** dev.loping an accurate clas.ification model,only fres. and s.fe fruits.reach cons.mers.reducing the ris.s.as.ociated with contaminated ***,the propos.d approach will hav. a s.gnificant impact on the food indus.ry for efficient fruit dis.ribution and als. benefit cus.omers.to purchas. fres. fruits.

关键词： Rotten fruit detection s.elf life deep learning conv.lutional neural network machine learning gaus.ian naïv. bayes random fores. v.s.al geometry group16

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A harmonis.tion approach to traditional Chines. medicine regis.ration in As.an countries

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Journal of Traditional Chines. Medical s.iences 2024年第2期11卷 143-147页

作者： Fung v.s.W.C. Independent s.holar 2 Woodward Place St Ives NSW 2075 Australia

The traditional Chines. medicine (TCM) indus.ry is.critical to not only for public health but als. for economic growth. According to the European Union (EU) directiv.s. under the EU framework for (traditional) herbal medicinal products. herbal medicines.with long his.ory of us. can be regis.ered in EU. Howev.r, there is.a condition in this.directiv. in which only thos. that hav. at leas. 10–15 years.in the EU market are accepted for regis.ration and/or marketing authorization. In author opinion, the condition of 10–15 years.of us. in EU countries.s.t within the EU regulatory framework is.with cons.deration of the genetic differences.which can res.lt in v.riation in adv.rs. drug res.ons.s.among different world populations. With this.concept in mind, it is.reas.nable to project the principal of the EU directiv. to the As.an countries.where TCM is.originated. Countries.like China, s.ngapore, Japan and s.uth Korea that hav. well es.ablis.ed drug regis.ration framework are in bes. pos.tion in executing the bes. practice and facilitate harmonization of regis.ration for TCM within the region. Furthermore, the regis.ration proces. its.lf allows.more s.fety and efficacy data to be collected s.s.emically before and after product regis.ration/marketing authorization. Thes. are v.luable information for future drug dev.lopment. The therapeutic v.lue of TCM is.limitles., it has.been left out in the EU regulatory framework, and the opportunity for it to be expanded and carried forward in modern medicines.is.s.adowed by the limited number of TCM that are qualified to be regis.ered under the EU regulatory framework. An early es.ablis.ment of a harmonized ris.-bas.d regis.ration proces. for TCM in As.an countries.is.important. This.will s.rengthen the databas. to s.bs.antiate the his.ory of s.fe us. and further pres.rv.ng and expanding the therapeutic v.lues.of TCM within and beyond the As.an region. © 2024 Beijing Univ.rs.ty of Chines. Medicine

关键词： As.an countries Harmonization Population genetic Regis.ration Traditional Chines. medicines

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Rigidity s.mmetry Line for Thermodynamic Fluid Equations.of-s.ate

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Journal of Modern Phys.cs 2024年第5期15卷 613-633页

作者： Les.ie v. Woodcock Department of Phys.cs University of Algarve Faro Portugal

We report progres. towards.a modern s.ientific des.ription of thermodynamic properties.of fluids.following the dis.ov.ry (in 2012) of a coexis.ing critical dens.ty hiatus.and a s.percritical mes.phas. defined by percolation trans.tions. The s.ate functions.dens.ty ρ(p,T), and Gibbs.energy G(p,T), of fluids. e.g. COs.b>2s.b>, Hs.b>2s.b>O and argon exhibit a s.mmetry characteris.d by the rigidity, ω = (dp/dρ)s.b>Ts.b>, between gas.ous.and liquid s.ates.along any is.therm from critical (Ts.b>cs.b>) to Boyle (Ts.b>Bs.b>) temperatures. on either s.de of the s.percritical mes.phas.. Here, us.ng experimental data for fluid argon, we inv.s.igate the low-dens.ty clus.er phys.cs.des.ription of an ideal dilute gas.that obeys.Dalton’s.partial pres.ure law. Clus.er expans.ons.in powers.of dens.ty relate to a s.percritical liquid-phas. rigidity s.mmetry (Rs. line (ω = ρs.b>rs./s.b>(T) = RT) to gas.phas. v.rial coefficients. We s.ow that it is.continuous.in all deriv.tiv.s. linear within s.able fluid phas., and relates.analytically to the Boyle-work line (BW) (w = (p/ρ)s.b>Ts.b> = RT), and to percolation lines.of gas.(PB) and liquid (PA) phas.s.by: ρs.b>BWs.b>(T) = 2ρs.b>PAs.b>(T) = 3ρs.b>PBs.b>(T) = 3ρs.b>Rs./s.b>(T)/2 for T Ts.b>Bs.b>. Thes. s.mple relations.ips.aris., becaus. the higher v.rial coefficients.(bs.b>ns.b>, n ≥ 4) cancel due to clus.ering equilibria, or become negligible at all temperatures.(0 T Ts.b>Bs.b>)s.b> s.b>within the gas.phas.. The Boyle-work line (p/ρs.b>BWs.b>)s.b>Ts.b> is.related exactly at lower dens.ties.as.T → Ts.b>Bs.b>, and accurately for liquid dens.ties. by ρs.b>BWs.b>(T) = −(bs.b>2s.b>/bs.b>3s.b>)s.b>Ts.b>. The Rs.line, ω(T) = RT, defines.a new liquid-dens.ty ground-s.ate phys.cal cons.ant (ρs.b>Rs./s.b>(0) = (2/3)ρs.b>BWs.b>(0) for argon). Giv.n the gas.liquid rigidity s.mmetry, the entire thermodynamic s.ate functions.below Ts.b>Bs.b> are obtainable from bs.b>2s.b>(T). A BW

关键词： Liquid-s.ate Theory Clus.er Phys.cs Percolation Lines Fluid Thermodynamics Boyle Line Rigidity-s.mmetry Line

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