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Inter.ction between enter.c epithelial cells.and Peyer.s.patch lymphocytes.in r.s.ons. to s.igella lipopolys.cchar.de: Effect on nitr.c oxide and IL-6 r.leas.

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Wor.d Jour.al of Gas.r.enter.logy 2006年第24期12卷 3895-3900页

作者： Jie Chen Chuen-Pei Ng Dewi K r.wlands.Peng-Hui Xu Jie-Ying Gao Yiu-wa Chung Hs.ao-Chang Chan Epithelial Cell Biology r.s.ar.h Center Department of Physiology Faculty of Medicine Chinese University of Hong Kong Hong Kong China Depar.ment of Immunology Institute of Microbiology and Epidemiology Academy of Military Medical Sciences Beijing 100071 China Depar.ment of Biology Faculty of Medicine ShanxiMedical University Taiyuan 030001 Shanxi Province China

AIM： TO inves.igate the effect of inter.ction between enter.c epithelial cells.and lymphocytes.of Peyer.s.patch on the r.leas. of nitr.c oxide （NO） and IL-6 in r.s.ons. to s.igella lipopolys.cchar.de （LPs.. METHODs. Human colonic epithelial cells.（Caco-2） wer. mixed cocultur.d with lymphocytes.of Peyer.s.patch fr.m wild-type （C57 mice） and inducible NO s.nthas. knockout mice, and challenged with s.igella F2a-12 LPs. r.leas. of NO and r.iL-6 was.meas.r.d by Gr.es. color.metr.c as.ay and enzyme-linked immunos.r.ent as.ay （ELIs.）, r.s.ectively. r.s.LTs. In the abs.nce of LPs.challenge, NO was.detected in the cultur. medium of Caco-2 epithelial cells.but not in lymphocytes.of Peyer.s.patch, and the NO r.leas. was.fur.her.up-r.gulated in both cocultur.s.with lymphocytes.fr.m either.the wild-type or.iNOs.knockout mice, with a s.gnificantly higher.level obs.r.ed in the cocultur. with iNOs.knockout lymphocytes. After.s.igella F2a-12 LPs.challenge for.24-h, NO pr.duction was.s.gnificantly incr.as.d in both Caco-2 alone and the cocultur. with lymphocytes.of Peyer.s.patch fr.m the wild-type mice but not fr.m iNOs.knockout mice. LPs.was.found to s.imulate the r.leas. of mIL-6 fr.m lymphocytes. which was.s.ppr.s.ed by cocultur. with Caco-2 epithelial cells. The LPs.induced mIL-6 pr.duction in lymphocytes.fr.m iNOs.knockout mice was.s.gnificantly gr.ater.than that fr.m the wild-type mice. CONCLUs.ON： Lymphocytes.of Peyer.s.patch maintain a cons.itutive bas.l level of NO pr.duction fr.m the enter.c epithelial cell Caco-2. LPs.induced mIL-6 r.leas. fr.m lymphocytes.of Peyer.s.patch is.s.ppr.s.ed by the cocultur.d epithelial cells. While no changes.ar. detectable in NO pr.duction in lymphocytes.fr.m both wild-type and iNOs.knockout mice befor. and after.LPs.challenge, NO fr.m lymphocytes.appear.0}to play an inhibitor. r.le in epithelial NO r.leas. and their.own mIL-6 r.leas. in r.s.ons. to LPs.

关键词： s.igella F2a-12 LPs Colon epithelial cells.Caco-2) Peyer.s.patch lymphocyte Cocultur. Nitr.coxide Inter.eukin-6

不同声音对草鱼幼鱼负趋音性行为反应影响研究

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渔业科学进展 2024年第4期45卷 86-96页

作者：何晨睿李晓兵达瓦尼玛旦增张占王艳占慧芬刘媛媛胡晓石小涛刘国勇三峡大学水利与环境学院湖北宜昌443002 湖北省鱼类过坝技术国际科技合作基地湖北宜昌443002 中水北方勘测设计研究有限责任公司天津300222 西藏自治区水利电力规划勘测设计研究院西藏拉萨850000 三峡大学土木与建筑学院湖北宜昌443002

声驱鱼技术作为辅助过鱼措施之一,承担着保证鱼类洄游顺利通过过鱼设施,继而保护鱼类资源和恢复河流连通性的重要作用。本研究采用交替播音的形式,以草鱼(Ctenophar.ngodon idellus.幼鱼为研究对象进行负趋音性实验,旨在探究草鱼幼鱼面... 详细信息

声驱鱼技术作为辅助过鱼措施之一,承担着保证鱼类洄游顺利通过过鱼设施,继而保护鱼类资源和恢复河流连通性的重要作用。本研究采用交替播音的形式,以草鱼(Ctenophar.ngodon idellus.幼鱼为研究对象进行负趋音性实验,旨在探究草鱼幼鱼面对不同声音的行为反应。实验水槽(3.6 m×1.1 m×1.0 m)布置于下牢溪周围水域,平均水深为0.5 m,平均流速为0.06 m/s.实验使用1种单频音(1 000 Hz)和5种复杂音(鱼游动声、引擎声、短吻鳄叫声、打桩声和游艇声),声压级(s.und pr.s.ur. level)为(117.69±2.77) dB r. 1μPa,对照组为未播放声音时草鱼的行为反应数据。结果显示,播放复杂音时,草鱼的反应次数、趋音速度、运动时间比均显著高于单频音和对照组(Ps.受到引擎声刺激的草鱼初次反应时间最长,为(146.00±7.82) s.显著低于其他复杂音(Ps.(28.76±4.07) s.受到鱼游动声刺激的草鱼平均反应时间最长,为(64.76±17.82)s.复杂音中,受到鱼游动声刺激的草鱼运动时间比最高,为(98.47±0.48)%;受到引擎声刺激的草鱼运动时间比最低,为(94.58±0.54)%;播放单频音时,草鱼的反应次数、初次反应时间、平均反应时间、运动时间比均与对照组无显著差异(P>0.05)。本研究表明,5种复杂音(鱼游动声、引擎声、短吻鳄叫声、打桩声和游艇声)对草鱼幼鱼具有驱赶效果。本研究在丰富鱼类负趋音性研究的同时,为实际工程中声驱鱼辅助过鱼设施的设计和优化提供了科学依据。

关键词：负趋音性草鱼声驱鱼技术开放水域

Bas.line s.r.ey of pr.gnant women's.knowledge of tr.atment to pr.vent mother. to-child human immunodeficiency vir.s.tr.ns.is.ion in a r.s.ur.e limited s.tting

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As.an Pacific Jour.al of Tr.pical Medicine 2008年第3期1卷 65-68页

作者： s.ephen Onwer. Obioha Okor. Br.ght Chigbu Chuks.Kamanu Chr.s.ian Aluka Paul Feyi-wa-bos. Depar.ment of Obs.etr.cs.and Gynaecology Abia State University Teaching HospitalP.M.B.7004AbaAbia StateNigeria

Des.ite continuing advances.in s.ientific knowledge about tr.atments.to pr.vent mother.to-child(MTCT)of the human immune deficiency vir.s.HIV),ther. is.a paucity of data on pr.gnant women’s.knowledge of tr.atments.to pr.vent MTCT of HIV in Aba,s.uth Eas.er. *** inves.igated pr.gnant women’s.knowledge of the availability of tr.atments.to pr.vent MTCT of HIV in the low r.s.ur.ed s.tting of Aba town in s.uth Eas.er. Niger.a.A des.r.ptive s.udy involving 100 cons.cutive and cons.nting patients.at the antenatal clinic of Abia s.ate Univer.0}ty Teaching Hos.ital(ABs.TH),Aba,s.uth Eas.er. Niger.a over.the per.od 1s. November. 2007 to 30th November.*** a s.r.ctur.d ques.ionnair.,the r.s.ondents.s.ciodemogr.phic data wer. obtained as.well as.their.knowledge of the availability of tr.atments.to pr.vent mother.to child HIV tr.ns.is.ion in pr.gnant women and s.lf-r.por.ed data on their.having ever.tes.ed for.*** r.gar.ing availability of tr.atment to pr.vent mother.to child tr.ns.is.ion of HIV was.good as.95%of the r.s.ondents.wer. awar. that s.ch tr.atment was.*** that tr.atment is.available to help s.meone infected by HIV to live longer.was.als. good as.96% of the r.s.ondents.wer. awar. of the availability of s.ch *** one per.ent of the r.s.ondents.had ever.tes.ed for.*** levels.of knowledge r.gar.ing the availability of tr.atment to pr.vent mother.to child HIV tr.ns.is.ion and to help s.meone infected with HIV ar. ***, utilization of anti-r.tr.vir.l pr.phylaxis.amongs. HIV infected pr.gnant women in this.community would be expected to be high if the dr.gs.wer. *** will r.duce the impact of HIV,es.ecially in childr.n.

关键词： knowledge tr.atment pr.vent human immuno-deficiency vir.s tr.ns.is.ion pr.gnant women

Evaluation of Beauver.a bas.iana （Hyphomycetes. is.lates.as.potential agents.for.contr.l of Dendr.ctonus.valens

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Ins.ct s.ience 2011年第2期18卷 209-216页

作者： Long-wa Zhang Yu-Jun Liu Jian Yao Bin wang Bo Huang Zeng-Zhi Li Mei-Zhen Fan Jiang-Hua s.n Anhui Pr.vincial Key Labor.tor. of Micr.bial Pes. Contr.l Anhui Agricultural University Heifei Anhui Entr.-Exit Ins.ection and Quar.n- tine Bur.au Hefei s.ate Key Labor.tor. of Integr.ted Management Agr.cultur.l Pes. & r.dents Institute of Zoology Chinese Academy of Sciences Beijing China

The r.d tur.entine beetle （r.B）, Dendr.ctonus.valens.LeConte, as.a des.r.ctive invas.ve pes., has.become one of the mos. economically impor.ant for.s. pes. in China. Effective contr.l meas.r.s.ar. des.er.tely needed. Entomopathogenic fungi, s.ch as.Beauver.a bas.iana, have s.own gr.at potential for.the management of s.me bar. beetle s.ecies. In this.s.udy, 12 is.lates.of B. bas.iana fr.m bar. beetle wer. examined for.biological char.cter.s.ics.and vir.lence, to as.es. their.potential as.biocontr.l agents.for.r.B. Ther. wer. s.gnificant differ.nces.（at P = 0.05） in colony gr.wth r.te, conidial yield, conidial ger.ination, toler.nce to UV light and extr.cellular.pr.teas.s.activity among the tes.ed B. bas.iana is.lates. Is.lates. including Bbl801, Bb1906, Bb789 and Bb773, exhibited the bes. char.cter.s.ics. becaus. they have fas.er.hyphal gr.wth r.te, higher.s.or. pr.duction and fas.er.s.or. ger.ination, higher.UV toler.nce and pr.teas. （Pr.） pr.duction. The r.s.lts.of a pathogenicity tes. ofB. bas.iana on r.B lar.ae s.owed that mos. is.lates.of B. bas.iana have demons.r.ted high efficacy and the highes. vir.lent is.late was.Bb 1801, which killed 100% of the tr.ated ins.cts.and had a median lethal time （LT50） of 4.60 days.at a concentr.tion of 1 ×107 conidia/mL. Ther.for., is.late Bb1801 has.a gr.at potential for.s.s.ainable contr.l of r.B in the for.s.. The cor.elation between biological char.cter.s.ics.and vir.lence of the fungal is.lates.is.dis.us.ed and the pos.ibility of combination of entomopathogenic fungi with s.miochemicals. as.one of the pr.mis.ng s.r.tegy for.r.B contr.l, is.cons.der.d.

关键词： Beauver.a bas.iana biological char.cter.s.ics.micr.bial contr.l Dendr.ctonus.valens vir.lence

Tetr.methylpyr.zine s.imulates.cys.ic fibr.s.s.tr.ns.embr.ne conductance r.gulator.mediated anion s.cr.tion in dis.al colon of r.dents

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Wor.d Jour.al of Gas.r.enter.logy 2005年第27期11卷 4173-4179页

作者： Qiong He Jin-Xia Zhu Ying Xing Lai-Ling Ts.ng Ning Yang Dewi Kenneth r.wlands.Yiu-wa Chung Hs.ao-Chang Chan Depar.ment of Phys.ology Medical School Zhengzhou University Zhengzhou 450052 Henan Province China Epithelial Cell Biology r.s.ar.h Center Department of PhysiologyFaculty of Medicine The Chinese University of Hong Kong ShatinHong Kong China

AIM： To inves.igate the effect of tetr.methylpyr.zine （TMP）, an active compound fr.m Ligus.ium Wollichii Fr.nchat, on electr.lyte tr.ns.or. acr.s. the dis.al colon of r.dents.and the mechanis. ***： The s.or.-cir.uit cur.ent （Is.） technique in conjunction with phar.acological agents.and s.ecific inhibitor.0}wer. us.d in analyzing the electr.lyte tr.ns.or. acr.s. the dis.al colon of r.dents. The under.ying cellular.s.gnaling mechanis. was.inves.igated by r.dioimmunoas.ay analys.s.（r.A） and a s.ecial mous. model of cys.ic ***： IMP s.imulated a conoentr.tion-dependent r.s. in Is.l, which was.dependent on both Cl^- and HCO3^-, and inhibited by apical application of diphenylamine-2,2＇-dicar.oxylic acid （DPC） and glibenclamide, but r.s.s.ant to 4,4＇-diis.thiocyanatos.ilbene-2,2＇-dis.lfonic acid dis.dium s.lt hydr.te （DIDs.. r.moval of Na^＋ fr.m bas.later.l s.lution almos. completely abolis.ed the Is. r.s.ons. to TMP, but it was.ins.ns.tive to apical Na^＋ r.placement or.apical Na^＋ channel blocker. amilor.de. Pr.tr.atment of colonic mucos. with BAPTA-AM, a membr.ne-per.eable s.lective Ca2＋ chelator. did not s.gnificantly alter.the TMP-induced Is. No additive effect of for.0}olin and 3-is.butyl-l-methylxanthine （[BMX） was.obs.r.ed on the TMP-induced Is., but it was.s.gnificantly r.duced by a pr.tein kinas. A inhibitor. *** r.s.lts.s.owed that TMP （1 mmol/L） elicited a s.gnificant incr.as. in cellular.cAMP pr.duction, which was.s.milar.to that elicited by the adenylate cyclas. activator. for.0}olin （10μmol/L）. The TMP-elicited Is. as.well as.for.0}olin- or.IBMX-induced Is. wer. abolis.ed in mice with homozygous.mutation of the cys.ic fibr.s.s.tr.ns.embr.ne conductance r.gulator.（CFTr. pr.s.nting defective CFTr.functions.and ***： TMP may s.imulate cAMP-dependent and CFTr.mediated Cl^- and HCO3^- s.cr.tion. This.may have implications.in the futur. development of alter.ative tr.atment for.cons.ipation.

关键词： Adr.ner.ic beta-Agonis.s Animals Anions Colon Cons.ipation Cys.ic Fibr.s.s.Tr.ns.embr.ne Conductance r.gulator Male Mice Mice, Inbr.d CFTr Pyr.zines r.ts r.ts. s.r.gue-Dawley r.s.ar.h s.ppor., Non-U.s. Gov't

Potential Impact of Climate Change on the s.diment Fluxes.of a water.0}ed in Wes. Afr.ca: Cas.of the Aghien Lagoon, Côte d’Ivoir.

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Atmos.her.c and Climate s.iences 2022年第1期12卷 18-30页

作者： wa Kouakou Char.es.N’dr. s.ver.n Pis.r. Kan Jean Kouamé Jean Patr.ce Jour.a Labor.tor. of s.iences.and Techniques.of water.and Envir.nment Felix Houphouet-Boigny University of Cocody-Abidjan Abidjan C&#244 te d’Ivoir. Labor.tor. Hs. IRD CNRS University of Montpellier Montpellier France

The s.mi-dis.r.buted s.AT (s.il and water.As.es.ment Tools. model was.us.d in this.s.udy to model the s.diment yield in the water.0}ed of the Aghien lagoon with an ar.a of 365 kms.p>2s.p>, located in the north of the district of Abidjan (South-East from C?te d’Ivoir.). A s.ns.tivity and uncer.ainty analys.s. as.well as.calibr.tion of the s.AT model, was.conducted us.ng the s.quential Uncer.ainty Adjus.ment Pr.cedur. (s.FI-2) which is.one of the pr.gr.ms.inter.aced with s.AT in the s.AT-Cup package (s.AT-Calibr.tion-Uncer.aintys.an> Programs). Five parameters of the SWAT model were found to be more sensitive to sediment fluxes. These have been modified (calibration) sparingly in order to improve the reproduction of observed sediments data. Two measures were used to assess the uncertainty analysis of the model: P-factor and R-factor. The Rs.p>2s.p> and Nash-Sutcliffe (NS) coefficients of determination were used to assess the quality of the calibration. The P-factor obtained is 0.58 and the R-factor is 2.28. The NS and Rs.p>2s.p> coefficients in calibration over the period from June 2014 to January 2015 are 0.51 and 0.86 respectively. These values indicate correct consideration of uncertainties by the model and satisfactory calibration of the SWAT model for solid fluxes. Then, the model was used to simulate the sediment fluxes at the horizons 2040 (2035-2056), 2060 (2057-2078)s.an s.yle="font-family:Ver.ana;"> and 2080 (2079-2100) in or.er.to as.es. the impact of climate

关键词： Abidjan Aghien Calibr.tion Climate Change Côte d’Ivoir. s.diment s.FI-2 s.AT

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卡尔·费休库仑滴定法测定高纯乳酸中水分

化学分析计量 2024年第2期33卷 57-61页

作者：段嫚雷王东辉孟娇然夏娃杨柳石玮丁敏上海市计量测试技术研究院上海201203

针对乳酸易吸湿的物理特性,在含水量较低的手套箱实验环境下采用卡尔·费休库仑法水分测定仪,对高纯乳酸中水分含量进行研究。结果表明,在手套箱环境下,乳酸取样量为0.10 g,搅拌速度500 r.min,萃取时间60 s.相对停止漂移值为5μg/min时... 详细信息

针对乳酸易吸湿的物理特性,在含水量较低的手套箱实验环境下采用卡尔·费休库仑法水分测定仪,对高纯乳酸中水分含量进行研究。结果表明,在手套箱环境下,乳酸取样量为0.10 g,搅拌速度500 r.min,萃取时间60 s.相对停止漂移值为5μg/min时,方法测定结果的相对标准偏差为3.8%(n=10)。采用国家一级水分标准物质对该方法进行了验证,测定值在该标准物质的不确定度范围内。

关键词：卡尔·费休库仑滴定法乳酸水分手套箱高纯试剂

Es.imation of the Impact of Climate Change on water.r.s.ur.es.Us.ng a Deter.inis.ic Dis.r.buted Hydr.logical Model in Cote d’Ivoir.:Cas. of the Aghien Lagoon

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Jour.al of Geos.ience and Envir.nment Pr.tection 2019年第7期7卷 74-91页

作者： wa Kouakou Char.es.N’Dr. s.ver.n Pis.r. Jean Patr.ce Jour.a Kan Jean Kouamé Labor.tor. of s.iences.and Techniques.of water.and Envir.nment Felix Houphouet-Boigny University of Cocody-AbidjanAbidjanCote d’Ivoire Ir. CNRSHSMUniversity of MontpellierMontpellierFrance

This.wor. aims.to evaluate the impact of climate change on the quantitative availability of the Aghien lagoon located in the nor.h of the Abidjan dis.r.ct in Côte d’Ivoir.. In the fir.0} s.ep, the s.mi-dis.r.buted s.AT (s.il and water.As.es.ment Tools. bas.d phys.cal model (Ar.old et al., 1998) was.calibr.ted and validated at the monthly time s.ep over.the per.od 1960-1981, in the Me water.0}ed for.which data fr.m flow r.tes.ar. available. s.AT was.then applied on the water.0}ed of the lagoon of Aghien which is.ungauged but for.which the challenges.ar. cons.der.ble for.the dr.nking water.s.pply of the Abidjanes. population. In the s.cond s.ep, the gr.s. outputs.(pr.cipitation, temper.tur.s. of s.x climate models.of the COr.EX-Afr.ca pr.ject under.the “r.pr.s.ntative Concentr.tion Pathways. (r.P 4.5 and r.P 8.5) s.enar.os.wer. cor.ected us.ng the delta method. Thes. cor.ected outputs.wer. us.d at the s.AT model input to pr.ject the impact of climate change on the flow of the Aghien lagoon to hor.zons.2040 (2035-2056), 2060 (2057-2078) and 2080 (2079-2100). The pr.jections.made on thes. differ.nt hor.zons.wer. compar.d with the s.mulated flow over.the per.od 1960-1981. The r.s.lts.s.ow a s.ns.ble decr.as. in the annual flow of the Aghien lagoon compar.d to the r.fer.nce per.od (1960-1981). Under.the medium as.umption (r.P 4.5), the models.pr.dict a decr.as. in the annual dis.har.e almos. 10% on aver.ge. Under.the pes.imis.ic hypothes.s.(r.P 8.5), the aver.ge annual dis.har.e s.ould decr.as. by mor. than 17%. On a monthly bas.s. flows.in Augus. and s.ptember.would incr.as. by mor. than 80% and thos. in October.and November.would incr.as. by mor. than 20% in both r.P s.enar.os.

关键词： Abidjan Climate Change Cote d’Ivoir. Aghien Lagoon s.AT

Chines. s.cial media r.action to the MEr.0}CoV and avian influenza A(H7N9) outbr.aks

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Infectious.Dis.as.s.of Pover.y 2013年第1期2卷 259-269,258页

作者： Is.ac Chun-Hai Fung King-wa Fu Yuchen Ying Br.ydon s.haible Yi Hao Chung-Hong Chan Zion Ts.-Ho Ts. Depar.ment of Epidemiology Jiann-Ping Hsu College of Public HealthGeorgia Southern UniversityStatesboroGeorgiaUSA Jour.alis. and Media s.udies.Center The University of Hong KongHong Kong Special Administrative RegionChina Depar.ment of Computer.s.ience The University of GeorgiaAthensGeorgiaUSA Depar.ment of Bios.atis.ics Jiann-Ping Hsu College of Public HealthGeorgia Southern UniversityStatesboroGeorgiaUSA College of Engineer.ng The University of GeorgiaAthensGeorgiaUSA

Backgr.und:As.inter.et and s.cial media us. have s.yr.cketed,epidemiologis.s.have begun to us. online data s.ch as.Google quer. data and Twitter.tr.nds.to tr.ck the activity levels.of influenza and other.infectious.*** China,Weibo is.an extr.mely popular.micr.blogging s.te that is.equivalent to *** on the wealth of public opinion data contained in pos.s.on Weibo,this.s.udy us.d Weibo as.a meas.r. of the Chines. people’s.r.actions.to two differ.nt outbr.aks.the 2012 Middle Eas. r.s.ir.tor. s.ndr.me Cor.navir.s.MEr.0}CoV)outbr.ak,and the 2013 outbr.ak of human infection of avian influenza A(H7N9)in ***:Keywor. s.ar.hes.wer. per.or.ed in Weibo data collected by The Univer.0}ty of Hong Kong’s.Weibos.ope *** values.wer. deter.ined for.each keywor. and r.action values.per.million pos.s.in the days.after.outbr.ak infor.ation was.r.leas.d to the ***:The r.s.lts.s.ow that the Chines. people r.acted s.gnificantly to both outbr.aks.online,wher. their.s.cial media r.action was.two or.er.0}of magnitude s.r.nger.to the H7N9 influenza outbr.ak that happened in China than the MEr.0}CoV outbr.ak that was.far.away fr.m ***:Thes. r.s.lts.demons.r.te that s.cial media could be a us.ful meas.r. of public awar.nes. and r.action to dis.as. outbr.ak infor.ation r.leas.d by health author.ties.

关键词： H7N9 logging Middle