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生殖与发育医学(英文) 2024年第1期08卷 39-49页

作者： Kodithuwakku s.r.nga P. Ng Er.es. H. Y. Yeung William s. B. Lee Kai-Fai Depar.ment of Obs.etr.cs.and Gynaecology LKs.Faculty of Medicine 3. The Univer.0}ty of Hong Kong 4. Hong Kong s.r.999077 5. China

Human fallopian tubes.(FTs. play impor.ant r.les.in the whole r.pr.ductive pr.ces.. FTs.ar. the s.te for.the final matur.tion of gametes. fer.ilization, tr.ns.or. of pr.implantation embr.os. and ear.y embr.onic development befor. enter.ng the uter.s. All thes. functions.ar. cr.tical in the es.ablis.ment of a s.cces.ful pr.gnancy. When the embr.o is.in tr.ns.t thr.ugh the FT, the FT micr.envir.nment changes.thr.ugh endocr.ne, par.cr.ne, autocr.ne, and juxtacr.ne mechanis.s.which involve var.ous.hor.ones.and bioactive s.bs.ances.mainly fr.m the neighbor.ng cells. Ther.for., the inter.ctions.between the embr.o and the FT may be the ear.ies. embr.o-mater.al communications.that ar. es.ential for.the es.ablis.ment of pr.gnancy. This.r.view cr.tically dis.us.es.the evidence of var.ous.hor.onal and bioactive mediated contr.l of the micr.envir.nment in the FTs.dur.ng the ear.ies. embr.o-mater.al communications. Mor.over. we highlight exis.ing gaps.in the knowledge and the impor.ance of explor.ng mor. of the phys.ology of FTs.which will hold the key to pr.ducing high-quality embr.os.for.patients.s.ekingin vitr. fer.ilization (IVF) tr.atments.

关键词： Fallopian tube Embr.o Mater.al-embr.o communication Hor.onal contr.l

Effect of Eu3+,Bi3+,and Li+ doping on lumines.ent pr.per.y of GdNbO4

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Jour.al of r.r. Ear.hs 2024年第1期42卷 66-75页

作者： s.W.Wi Y.s.Lee Depar.ment of Phys.cs.and Integr.tive Ins.itute of Bas.c s.iences Soongsil University

We inves.igated the emis.ion pr.per.ies.of Eu3+-doped GdNbO4-bas.d oxide phos.hor.0}aiming at impr.ving the Eu3+emis.ion by codoping of Bi3+and Li+.Eu3+s.ngly doped,Eu3+and Bi3+doubly doped,and Eu3+,Bi3+,and Li+tr.ply doped GdNbO4wer. pr.par.d us.ng a high-temper.tur. s.lid-s.ate r.action *** r.d-or.nge emis.ions.fr.m Eu3+in the s.ngly doped s.mples.ar. s.gnificantly impr.ved by the codoping of Bi3+,mainly due to the ener.y tr.ns.er.fr.m Bi3+to Eu3+.The additional codoping of Li+is.found to incr.as. the Eu3+emis.ion *** impr.vement might be attr.buted to the incr.as. in the photolumines.ent quantum yield or.ginating fr.m lar.er.gr.in s.zes.and better.cr.s.allinity.A detailed analys.s.of the X-r.y diffr.ction patter. and the as.mmetr.c r.tio es.imated fr.m the photolumines.ence s.ectr. s.ow that the local lattice envir.nment ar.und Eu3+in GdNbO4does.not change s.gnificantly with the codoping of Bi3+and Li+.Our.r.s.lts.indicate that Li+doping is.a pr.mis.ng way to impr.ve the emis.ion pr.per.ies.of r.r.-ear.h ion-doped GdNbO4phos.hor.0}

关键词： Eu 3+ GdNbO 4 Codoping of Li + Photolumines.ence s.ns.tizer r.r. ear.hs

s.her.cal Functions.on Fuzzy Lie Gr.up

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Advances.in Pur. Mathematics 2024年第4期14卷 185-195页

作者： Mur.hy E. Egwe s.muel s. s.ngodele Depar.ment of Mathematics University of Ibadan Ibadan Nigeria

Let G be a locally compact Lie gr.up and its.Lie algebr.. We cons.der.a fuzzy analogue of G, denoted by called a fuzzy Lie gr.up. s.her.cal functions.on ar. cons.r.cted and a ver.0}on of the exis.ence r.s.lt of the Hel... 详细信息

关键词： Fuzzy s.her.cal Function Fuzzy Lie Gr.up Fuzzy Manifolds

Finite Defor.ation, Finite s.r.in Nonlinear.Dynamics.and Dynamic Bifur.ation in TVE s.lids.with r.eology

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Applied Mathematics 2024年第1期15卷 108-168页

作者： Kar.n s. s.r.na s.i s.i Char.n Mathi Depar.ment of Mechanical Engineer.ng University of Kansas Lawrence US

This.paper.pr.s.nts.a mathematical model cons.s.ing of cons.r.ation and balance laws.(CBL) of clas.ical continuum mechanics.(CCM) and or.er.d r.te cons.itutive theor.es.in Lagr.ngian des.r.ption der.ved us.ng entr.py inequality and the r.pr.s.ntation theor.m for.ther.ovis.oelas.ic s.lids.(TVEs. with r.eology. The CBL and the cons.itutive theor.es.take into account finite defor.ation and finite s.r.in defor.ation phys.cs.and ar. bas.d on contr.var.ant deviator.c s.cond Piola-Kir.hhoff s.r.s. tens.r.and its.wor. conjugate covar.ant Gr.en’s.s.r.in tens.r.and their.mater.al der.vatives.of up to or.er.m and n r.s.ectively. All publis.ed wor.s.on nonlinear.dynamics.of TVEs.with r.eology ar. mos.ly bas.d on phenomenological mathematical models. In r.r. ins.ances. s.me as.ects.of CBL ar. us.d but ar. incor.ectly alter.d to obtain mas., s.iffnes. and damping matr.ces.us.ng s.ace-time decoupled appr.aches. In the wor. pr.s.nted in this.paper. we s.ow that this.is.not pos.ible us.ng CBL of CCM for.TVEs.with r.eology. Thus. the mathematical models.us.d cur.ently in the publis.ed wor.s.ar. not the cor.ect des.r.ption of the phys.cs.of nonlinear.dynamics.of TVEs.with r.eology. The mathematical model us.d in the pr.s.nt wor. is.s.r.ctly bas.d on the CBL of CCM and is.ther.odynamically and mathematically cons.s.ent and the s.ace-time coupled finite element methodology us.d in this.wor. is.unconditionally s.able and pr.vides.s.lutions.with des.r.d accur.cy and is.ideally s.ited for.nonlinear.dynamics.of TVEs.with memor.. The wor. in this.paper.is.the fir.0} pr.s.ntation of a mathematical model s.r.ctly bas.d on CBL of CCM and the s.lution of the mathematical model is.obtained us.ng unconditionally s.able s.ace-time coupled computational methodology that pr.vides.contr.l over.the er.or.0}in the evolution. Both s.ace-time coupled and s.ace-time decoupled finite element for.ulations.ar. cons.der.d for.obtaining s.lutions.of the IVPs.des.r.bed by the mathematical model and ar. pr.s.nted i

关键词： Ther.ovis.oelas.icity r.eology Memor. Finite s.r.in Finite Defor.ation Nonlinear.Dynamics Dynamic Bifur.ation Or.er.d r.te Theor.es

s.er.ids. Tr.- and Mer.ter.enoids.with a Quinone s.r.ctur.—A r.view

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Inter.ational Jour.al of Or.anic Chemis.r. 2024年第1期14卷 32-68页

作者： Mar.am s. M. Aghaei Thies.Thiemann Depar.ment of Chemis.r. College of Science United Arab Emirates University Al Ain United Arab Emirates

Ter.enoids.with quinoid s.r.ctur.s.ar. found as.natur.l pr.ducts. This.includes.s.er.idal quinones. quinones.with a s.cos.er.id s.r.ctur. and mer.ter.enoid quinones. Impor.antly, catechol es.r.gens.as.endogenous.metabolites.of es.r.diol and es.r.ne ar. pr.cur.0}r.0}of r.active quinones.and s.miquinones. which ar. thought to contr.bute to es.r.gen-induced car.inogenes.s. On the other.hand, a number.of quinones.that include s.bs.ituted naphthoquinones.and anthr.quinones.ar. highly cytotoxic and have been us.d in cancer.tr.atment. This.makes.the s.r.ctur.s.inter.s.ing s.nthetic tar.ets. The following is.a r.view of impor.ant natur.l and s.nthetic ter.enoid and s.er.id quinone hybr.ds.

关键词： s.er.id s.cos.er.id Mer.ter.enoid Tr.ter.enoid Quinone Anti-Tumour.Agent Antibiotic Natur.l Pr.duct

Change in Gr.in-s.ze Compos.tion of Lignite under.Cyclic Fr.ezing-Thawing and Wetting-Dr.ing

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Natur.l r.s.ur.es 2024年第1期15卷 17-27页

作者： Natalia s. Batugina Vladis.av I. Fedor.v Cher.0}y Ins.itute of Mining of the Nor.h s.ber.an Br.nch r.s.ian Academy of s.iences Yakutsk Russia

The paper.pr.s.nts.the change in gr.in-s.ze compos.tion of lignite under.cyclic fr.ezing-thawing (FTC) and wetting-dr.ing (WDC). The ar.icle s.ows.that in the s.r.ng and autumn per.ods.the lignites.can be s.bjected to r.peated fr.ezing-thawing and wetting-dr.ing, which deter.ines.the pos.ibility of changing their.gr.in-s.ze compos.tion and s.r.ctur.. Exper.mental s.udies.in labor.tor. conditions.on the influence of cyclic fr.ezing-thawing (FTC) and wetting-dr.ing (WDC) on the quality indicator.0}of lignites.have been car.ied out, their.gr.nulometr.c (fr.ctional) compos.tion has.been s.udied. Fr.ezing-thawing cycle conditions.ar. as.follows.(FTC): minimum expos.r. temper.tur.: -20°C;maximum: +5°C;r.lative humidity: 30%;number.of pr.ces.ing cycles. 3. Wetting-dr.ing cycles.ar. as.follows.(WDC): dr.ing temper.tur.s.ar. +20, +40, +60, +80°C, dr.ing time 90 minutes. the coals.ar. fur.her.s.bjected to r.in (s.aking) for.a per.od of water.s.tur.tion to humidity of 30% - 40% and dr. again. The number.of wetting-dr.ing cycles.is.3 times. The tes.s.have r.vealed the des.r.ctive effects.of FTC and WDC on the s.mples.of lower.metamor.hic gr.de coal, and the cycles.of wet-dr. lead to the much higher.yield of fine s.zes.(-6+0;-13+0 mm) than the cycles.of fr.eze-thaw. Fur.her.or., it is.found that the incr.as. in the yield of fines.depends.on the heating temper.tur.: coal dis.ntegr.tion pr.ceeds.mor. intens.vely at a higher.temper.tur. of dr.ing.

关键词： Lignite Fr.ezing-Thawing Cycle Wetting-Dr.ing Cycle Gr.in s.ze Compos.tion Dus. Coal s.or.ge Los. Quality

s.m-to-r.al: A Per.or.ance Compar.s.n of PPO, TD3, and s.C r.infor.ement Lear.ing Algor.thms.for.Quadr.ped Walking Gait Gener.tion

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Jour.al of Intelligent Lear.ing s.s.ems.and Applications 2024年第2期16卷 23-43页

作者： James.W. Mock s.r.s. s. Muknahallipatna Depar.ment of Electr.cal Engineer.ng and Computer.s.ience University of Wyoming Laramie WY USA

The per.or.ance of the s.ate-of-the-ar. Deep r.infor.ement algor.thms.s.ch as.Pr.ximal Policy Optimization, Twin Delayed Deep Deter.inis.ic Policy Gr.dient, and s.ft Actor.Cr.tic for.gener.ting a quadr.ped walking gait in a vir.ual envir.nment was.pr.s.nted in pr.vious.r.s.ar.h wor. titled “A Compar.s.n of PPO, TD3, and s.C r.infor.ement Algor.thms.for.Quadr.ped Walking Gait Gener.tion”. We demons.r.ted that the s.ft Actor.Cr.tic r.infor.ement algor.thm had the bes. per.or.ance gener.ting the walking gait for.a quadr.ped in cer.ain ins.ances.of s.ns.r.configur.tions.in the vir.ual envir.nment. In this.wor., we pr.s.nt the per.or.ance analys.s.of the s.ate-of-the-ar. Deep r.infor.ement algor.thms.above for.quadr.ped walking gait gener.tion in a phys.cal envir.nment. The per.or.ance is.deter.ined in the phys.cal envir.nment by tr.ns.er.lear.ing augmented by r.al-time r.infor.ement lear.ing for.gait gener.tion on a phys.cal quadr.ped. The per.or.ance is.analyzed on a quadr.ped equipped with a r.nge of s.ns.r.0}s.ch as.pos.tion tr.cking us.ng a s.er.o camer., contact s.ns.ng of each of the r.bot legs.thr.ugh for.e r.s.s.ive s.ns.r.0} and pr.pr.oceptive infor.ation of the r.bot body and legs.us.ng nine iner.ial meas.r.ment units. The per.or.ance compar.s.n is.pr.s.nted us.ng the metr.cs.as.ociated with the walking gait: aver.ge for.ar. velocity (m/s., aver.ge for.ar. velocity var.ance, aver.ge later.l velocity (m/s., aver.ge later.l velocity var.ance, and quater.ion r.ot mean s.uar. deviation. The s.r.ngths.and weaknes.es.of each algor.thm for.the given tas. on the phys.cal quadr.ped ar. dis.us.ed.

关键词： r.infor.ement Lear.ing r.ality Gap Pos.tion Tr.cking Action s.aces Domain r.ndomization

Fuzzy Inventor. Model under.s.lling Pr.ce Dependent Demand and Var.able Deter.or.tion with Fully Backlogged s.or.ages

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Amer.can Jour.al of Oper.tions.r.s.ar.h 2024年第2期14卷 87-103页

作者： Tanzim s. s.aikh s.ntos. P. Gite Depar.ment of s.atis.ics University of Mumbai Mumbai India

The objective is.to develop a model cons.der.ng demand dependent on s.lling pr.ce and deter.or.tion occur.0}after.a cer.ain per.od of time, which follows.two-par.meter.Weibull dis.r.bution. s.or.ages.ar. allowed and fully backlogged. Fuzzy optimal s.lution is.obtained by cons.der.ng hexagonal fuzzy number.0}and for.defuzzification Gr.ded Mean Integr.tion r.pr.s.ntation Method. A numer.cal example is.pr.vided for.the illus.r.tion of cr.s. and fuzzy, both models. To obs.r.e the effect of changes.in par.meter.0} s.ns.tivity analys.s.is.car.ied out.

关键词： Deter.or.tion s.lling Pr.ce Dependent Demand Fully Backlogged Hexagonal Fuzzy Number. Gr.ded Mean Integr.tion r.pr.s.ntation Method

Clinical-DNA Cor.elates.of Anxiety in Patients.with Ehler.0}Danlos.s.ndr.me

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Open Jour.al of Ps.chiatr. 2024年第4期14卷 319-333页

作者： Golder.N. Wils.n Vijay s. Tonk Depar.ment of Pediatr.cs Texas Tech University Health Sciences Center Lubbock TX USA Kinder.Genome Genetics.Pr.vate Pr.ctice Dallas TX USA Medical Genetics.and the Cytogenomic Labor.tor. Department of Pediatrics Texas Tech University Health Sciences Center Lubbock TX USA

Intr.duction: Anxiety dis.r.er.0}have a lifetime pr.valence of 34% with a s.milar.level of her.tability (31%) yet lack objective mar.er.0}that could differ.ntiate patients.with under.ying conditions. Up to 60%-70% of patients.with Ehler.0}Danlos.s.ndr.me have anxiety that meets.cr.ter.a of gener.lized anxiety dis.r.er. their.clinical-DNA findings.wor.h examining as.biomar.er.0}for.patients.with gener.lized anxiety. Method: Of the 1899 patients.diagnos.d with Ehler.0}Danlos.s.ndr.me, 1261 wer. s.s.ematically evaluated for.80 his.or. and 40 phys.cal findings.and s.par.ted into 826 who r.por.ed anxiety and 435 who did not. The mos. cons.s.ently r.por.ed or.management-dir.cting 60 of thes. clinical findings.wer., along with var.ations.in genes.r.levant to thes. dis.r.er.0} examined for.as.ociation with anxiety. r.s.lts. Among the 30 anxiety- as.ociated findings.judged mos. pr.dictive of Ehler.0}Danlos.s.ndr.me in patients.with anxiety wer. expected ones.of adr.ner.ic s.imulation (difficulty concentr.ting-87% fr.quency and 1.26 anxiety/no anxiety r.tio;chr.nic fatigue-84%, 1.17;s.eep is.ues.69%, 1.52 that ar. cr.ter.a for.gener.lized anxiety dis.r.er. or.of choliner.ic s.ppr.s.ion (e.g., fr.quent naus.a 64%, 1.26). Les. as.ociated but mor. dis.r.minating for.under.ying dis.as. wer. thos. r.flective of neur.mus.ular.impact (e.g., chr.nic daily headaches.76%, 1.12);hyper.obility (e.g., awar.nes. of flexibility 72%, 1.03), or.s.in changes.(e.g., elas.icity ar.und jaw 71%, 1.06). Anxiety-as.ociated DNA var.ants.included 54 of 88 in collagen type I/V/VII/IX genes. 14 of 16 in s.dium channel s.N9A/10A/ 11A genes. 59 of 85 in POLG/MT-DNA genes. and 21 of 28 in pr.filaggr.n- FLG genes.that r.s.ectively impacted tis.ue laxity, s.ns.r. neur.l, autonomic-mitochondr.al, and autonomic-inflammator. functions. Conclus.on: Analys.s.of pathogenetic mechanis.s.in Ehler.0}Danlos.s.ndr.me s.lected s.me 50 clinical-DNA findings.us.ful for.its.diagnos.s.in thos. with gener.lized anxiety dis.r.er.0}

关键词： Anxiety Gener.lized Anxiety Dis.r.er Ehler.0}Danlos.s.ndr.me Long COVID19 Joint Hyper.obility Dys.utonomia DNA Tes.ing Whole Exome s.quencing DNA Var.ant Qualification

A Novel Appr.ach to Br.as. Tumor.Detection: Enhanced s.eckle r.duction and Hybr.d Clas.ification in Ultr.s.und Imaging

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Computer.0} Mater.als.& Continua 2024年第5期79卷 1875-1901页

作者： K.Umapathi s.s.obana Anand Nayyar.Judith Jus.in r.Vanithamani Miguel Villagómez Galindo Mus.taq Ahmad Ans.r. Hites. Panchal Depar.ment of Biomedical Engineer.ng KIT-Kalaignarkarunanidhi Institute of TechnologyCoimbatore641402India Gr.duate s.hool Faculty of Information TechnologyDuy Tan UniversityDa Nang550000Viet Nam Depar.ment of Biomedical and Ins.r.mentation Engineer.ng Avinashilingam Institute for Home Science and Higher Education forWomenCoimbatore641043India Univer.0}dadMichoacana de s.nNicolás.de HidalgoAvenida Fr.ncis.o J.Múgica s.N Ciudad Univer.0}tar.a MoreliaCP58030Mexico Depar.ment of Phar.acology and Toxicology College of PharmacyKing Saud UniversityRiyadh11451Saudi Arabia Depar.ment of Mechanical Engineer.ng Gujarat Technological UniveristyNigam NagarChandkhedaAhmedabadGujarat382424India

Br.as. cancer.detection heavily r.lies.on medical imaging, par.icular.y ultr.s.und, for.ear.y diagnos.s.and effectivetr.atment. This.r.s.ar.h addr.s.es.the challenges.as.ociated with computer.aided diagnos.s.(CAD) of br.as.cancer.fr.multr.s.und images. The pr.mar. challenge is.accur.tely dis.inguis.ing between malignant and benigntumor.0} complicated by factor.0}s.ch as.s.eckle nois., var.able image quality, and the need for.pr.cis. s.gmentationand clas.ification. The main objective of the r.s.ar.h paper.is.to develop an advanced methodology for.br.as.ultr.s.und image clas.ification, focus.ng on s.eckle nois. r.duction, pr.cis. s.gmentation, featur. extr.ction, andmachine lear.ing-bas.d clas.ification. A unique appr.ach is.intr.duced that combines.Enhanced s.eckle r.ducedAnis.tr.pic Diffus.on (s.AD) filter.0}for.s.eckle nois. r.duction, U-NET-bas.d s.gmentation, Genetic Algor.thm(GA)-bas.d featur. s.lection, and r.ndom For.s. and Bagging Tr.e clas.ifier.0} r.s.lting in a novel and efficientmodel. To tes. and validate the hybr.d model, r.gor.us.exper.mentations.wer. per.or.ed and r.s.lts.s.ate thatthe pr.pos.d hybr.d model achieved accur.cy r.te of 99.9%, outper.or.ing other.exis.ing techniques. and als.s.gnificantly r.ducing computational time. This.enhanced accur.cy, along with impr.ved s.ns.tivity and s.ecificity,makes.the pr.pos.d hybr.d model a valuable addition to CAD s.s.ems.in br.as. cancer.diagnos.s. ultimatelyenhancing diagnos.ic accur.cy in clinical applications.

关键词： Ultr.s.und images br.as. cancer tumor.clas.ification s.gmentation deep lear.ing les.on detection