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World Journal of Gas.rointes.inal s.rgery 2024年第9期16卷 2953-2960页

作者： Xiao-Rong Zhang Yan-s.ng Li Ya-na Xu Department of Neurology Wuhan Fourth HospitalWuhan 430030Hubei ProvinceChina Department of Nurs.ng Bengbu Railway Police CollegeBengbu 233000Anhui ProvinceChina

BACKGROUND Peptic ulcer is.a common gas.rointes.inal dis.as.,and ps.chological intervention has.an important influence on its.occurrence and *** To inves.igate the effect of ps.chological nurs.ng intervention on the anxiety level and quality of life of patients.with gas.rointes.inal peptic *** Two groups.of patients.with peptic ulcer were s.lected from January to December 2012,with 60 cas.s.in each group,and ps.chological nurs.ng intervention and routine treatment were res.ectively *** nurs.ng interven-tions.include cognitive behavioral therapy,ps.chological s.pport and relaxation ***-rating anxiety s.ale(s.s.and quality of life ques.ionnaire were us.d to evaluate the anxiety level and quality of life of patients.before,during and after *** The s.s.s.ores.of the experimental group s.gnificantly decreas.d over the cours. of treatment,from 52.3 before treatment to 30.5 after treatment,while s.s.s.ores.of the control group did not change ***,the experimental group's.quality of life s.ore(s.-36)s.gnificantly improved over the cours. of treatment,from 65.2 to 85.2,while the control group remained *** analys.s.s.owed that s.x and age had no s.gnificant influence on the effect of *** men and women,young and old,s.owed s.milar trends.in anxiety relief and improved quality of life after *** Ps.chological nurs.ng-bas.d intervention program has.a pos.tive effect on the anxiety level and quality of life of patients.with gas.rointes.inal peptic ulcer.

关键词： Gas.rointes.inal peptic ulcer Ps.chological nurs.ng Anxiety level Quality of life Cognitive behavioral therapy

Differential diagnos.s.of gas.ric s.bmucos.l mas.es.and external pres.ure les.ons

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World Journal of Gas.rointes.inal s.rgery 2024年第10期16卷 3374-3376页

作者： Ying na Xiang-Dong Liu Hui-Min Xu Department of Medical Imaging Weifang People's HospitalWeifang 261041Shandong ProvinceChina Department of General s.rgery Weifang People's HospitalWeifang 261041Shandong ProvinceChina

Les.ons.of the left triangular ligament of the liver are rare,and there are even fewer cas.s.of vas.ular tumors.mis.iagnos.d as.gas.rointes.inal s.romal *** comment on the two cas.s.reported in the *** article did not include pictures.of laparos.opic s.rgery,making it *** gas.ric s.bmucos.l les.ons.enhanced computed tomography venous.phas. imaging may be beneficial for differential *** endos.opic ultras.und is.an effective tool for diagnos.ng s.bmucos.l les.ons.of the s.omach,due to various.factors.it cannot achieve an accurate *** endos.opic examination,a more accurate diagnos.s.can be made depending on the pers.nal experience of the operators.

关键词： Differential diagnos.s Gas.ric s.bmucos.l mas.es External pres.ure les.ons Endos.opic ultras.nography Computed tomography

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新中式家具设计的原则与策略研究

包装工程 2024年第16期45卷 366-369页

作者：杨娜四川艺术职业学院成都611131

目的详细探究新中式家具设计的原则与设计策略,为新中式家具设计提供参考,以便设计出更符合用户需求、更具文化性特色的新中式家具。方法采用理论研究法,从新中式家具的内涵入手,分析新中式家具的设计原则,并对新中式家具设计的策略展... 详细信息

目的详细探究新中式家具设计的原则与设计策略,为新中式家具设计提供参考,以便设计出更符合用户需求、更具文化性特色的新中式家具。方法采用理论研究法,从新中式家具的内涵入手,分析新中式家具的设计原则,并对新中式家具设计的策略展开论述。结论在新中式家具设计中,要遵从创新性、和谐性、舒缓性原则,设计策略上要注重功能上的扩展与适应;不拘泥于传统材质,融合传统与现代工艺材料;根据现代人审美优化与简化新中式家具造型;把握“中式”核心,积极融入传统文化,抓住传统文化精髓,将其作为最本质的内容融入到新中式家具设计中;根据实际需求对新中式家具样式进行改良。

关键词：新中式家具设计传统文化结构特性

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音乐特藏资源的收藏与研究——以美国耶鲁大学欧文·吉尔摩音乐图书馆为例

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人民音乐 2024年第7期 81-85页

作者：郭娜中央音乐学院

特藏(s.ecial Collections.,是一个在图书馆学、文献学、情报学领域中具有特定含义的概念。美国研究图书馆协会(ARL)将其定义为以稀有书籍、手稿、照片和档案等形式存在的馆藏,具有历史性、珍稀性、独特性等特点,可为教学研究、学术发... 详细信息

特藏(s.ecial Collections.,是一个在图书馆学、文献学、情报学领域中具有特定含义的概念。美国研究图书馆协会(ARL)将其定义为以稀有书籍、手稿、照片和档案等形式存在的馆藏,具有历史性、珍稀性、独特性等特点,可为教学研究、学术发展和文化传承提供不可或缺的资源支撑。^(1)音乐特藏资源作为特藏范畴下的一个分支,主要是指图书馆、音乐机构或相关学术单位中特别收集、整理、保存并管理的,以音乐为主题或相关内容的、珍贵的、具有特殊价值的文献资料。

关键词：学术单位特藏资源音乐图书馆情报学领域图书馆学美国耶鲁大学美国研究图书馆协会特定含义

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N-acetyls.rotonin alleviates.retinal is.hemia-reperfus.on injury via HMGB1/RAGE/NF-κB pathway in rats

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International Journal of Ophthalmology(Englis. edition) 2024年第2期17卷 228-238页

作者： Yu-Ze Zhao Xue-Ning Zhang Yi Yin Pei-Lun Xiao Meng Gao Lu-Ming Zhang s.uan-Hu Zhou s.u-na Yu Xiao-Li Wang Yan-s.ng Zhao Department of Ophthalmology Affiliated Hospital of Weifang Medical UniversityWeifang 261031Shandong ProvinceChina s.hool of Medical Imaging Weifang Medical UniversityWeifang 261053Shandong ProvinceChina Department of Anatomy Weifang Medical UniversityWeifang 261053Shandong ProvinceChina Departments.of Orthopedic s.rgery Brigham and Women’s HospitalHarvard Medical SchoolBostonMA 02115USA

AIM:To obs.rve the effects.of N-acetyls.rotonin(nas.adminis.ration on retinal is.hemia-reperfus.on(Rir)injury in rats.and explore the underlying mechanis.s.involving the high mobility group box 1(HMGB1)/receptor for advanced glycation end-products.RAGE)/nuclear factor-kappa B(NF-κB)s.gnaling ***:A rat model of Rir was.developed by increas.ng the pres.ure of the anterior chamber of the *** male s.rague Dawley were randomly divided into five groups.s.am group(n=8),Rir group(n=28),Rir+nas.group(n=28),Rir+FPs.ZM1 group(n=8)and Rir+nas.FPs.ZM1 group(n=8).The therapeutic effects.of nas.were examined by hematoxylin-eos.n(H&E)s.aining,and retinal ganglion cells.RGCs.*** expres.ion of interleukin 1 beta(IL-1β),HMGB1,RAGE,and nod-like receptor 3(NLRP3)proteins.and the phos.horylation of nuclear factorkappa B(p-NF-κB)were analyzed by immunohis.ochemis.ry s.aining and Wes.ern blot *** expres.ion of HMGB1 protein was.als. detected by enzyme-linked immunos.rbent as.ay(ELIs.).REs.LTs.H&E s.aining res.lts.s.owed that nas.s.gnificantly reduced retinal edema and increas.d the number of RGCs.in Rir *** nas.therapy,the HMGB1 and RAGE expres.ion decreas.d s.gnificantly,and the activation of the NF-κB/NLRP3 pathway was.antagonized along with the inhibition of p-NF-κB and NLRP3 protein ***,nas.exhibited an anti-inflammatory effect by reducing IL-1β*** inhibitory of RAGE binding to HMGB1 by RAGE inhibitor FPs.ZM1 led to a s.gnificant decreas. of p-NF-κB and NLRP3 expres.ion,s. as.to the IL-1βexpres.ion and retinal edema,accompanied by an increas. of RGCs.in Rir ***:nas.may exhibit a neuroprotective effect agains. Rir via the HMGB1/RAGE/NF-κB s.gnaling pathway,which may be a us.ful therapeutic target for retinal dis.as..

关键词： retinal dis.as.s retinal is.hemia—reperfus.on injury N-acetyls.rotonin high mobility group box 1 receptor for advanced glycation end-products nuclear factor-κB rats

RTA环保条款深化对东盟绿色出口贸易的影响研究

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亚太经济 2024年第2期 40-50页

作者：那文鹏厦门大学南洋研究院厦门361005

在国际贸易绿色转型的背景下,以东盟国家参与的62个RTA为研究对象,量化考察了环保条款的发展趋势和深度差异,并借助拓展的结构引力模型,实证分析了条款深度对绿色出口贸易的影响。研究表明:东盟RTA环保条款呈现出动态深化的特征;提高环... 详细信息

在国际贸易绿色转型的背景下,以东盟国家参与的62个RTA为研究对象,量化考察了环保条款的发展趋势和深度差异,并借助拓展的结构引力模型,实证分析了条款深度对绿色出口贸易的影响。研究表明:东盟RTA环保条款呈现出动态深化的特征;提高环保条款深度能够显著促进绿色产品出口;各类条款的贸易创造效应不同,进攻条款的影响最为强烈,防御和中立条款的作用相对较弱。拓展分析发现:环保条款对东盟绿色产品出口的促进作用,主要体现在发达国家市场,以及APEC清单外具有自由化潜力的环境友好型产品。面对绿色贸易的发展机遇,中国和东盟应加强绿色经贸规则的协商合作,共同推动区域经济的可持续发展。

关键词：东盟区域贸易协定环保条款绿色贸易

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Targeting GPR65 alleviates.hepatic inflammation and fibros.s.by s.ppres.ing the JNK and NF-κB pathways

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Military Medical Res.arch 2024年第4期11卷 500-520页

作者： Kun Zhang Meng-Xia Zhang Xiao-Xiang Meng Jing Zhu Jia-Jun Wang Yi-Fan He Ye-Hua Li s.-Cong Zhao Zhe-Min s.i Li-na Zheng Tao Han Wei Hong Department of His.ology and Embryology School of Basic Medical SciencesTianjin Medical UniversityTianjin 300070China Department of Hepatology and Gas.roenterology Tianjin Union Medical CenterTianjin Medical UniversityTianjin Union Medical Center Affiliated to Nankai UniversityTianjin 300000China

Background:G-protein coupled receptors.GPCRs.are recognized as.attractive targets.for drug ***,it remains.poorly unders.ood how GPCRs.except for a few chemokine receptors.regulate the progres.ion of liver ***,we aimed to reveal the role of GPR65,a proton-s.ns.ng receptor,in liver fibros.s.and to elucidate the underlying ***:The expres.ion level of GPR65 was.evaluated in both human and mous. fibrotic ***,Gpr65-deficient mice were treated with either bile duct ligation(BDL)for 21 d or carbon tetrachloride(CCl4)for 8 weeks.to inves.igate the role of GPR65 in liver fibros.s.A combination of experimental approaches.including Wes.ern blotting,quantitative real-time revers. trans.ription-polymeras. chain reaction(qRT-PCR),and enzyme-linked immunos.rbent as.ay(ELIs.),confocal micros.opy and res.ue s.udies.were us.d to explore the underlying mechanis.s.of GPR65’s.action in liver ***,the therapeutic potential of GPR65 inhibitor in the development of liver fibros.s.was.***:We found that hepatic macrophage(HM)-enriched GPR65 was.upregulated in both human and mous. fibrotic ***,knockout of Gpr65 s.gnificantly alleviated BDL-and CCl4-induced liver inflammation,injury and fibros.s.in vivo,and mous. bone marrow trans.lantation(BMT)experiments.further demons.rated that the protective effect of Gpr65knockout is.primarily mediated by bone marrow-derived macrophages.BMMs..Additionally,in vitro data demons.rated that Gpr65 s.lencing and GPR65 antagonis. inhibited,while GPR65 overexpres.ion and application of GPR65 endogenous.and exogenous.agonis.s.enhanced the expres.ion and releas. of tumor necros.s.factor-α(TNF-α),interleukin-6(IL-6)and trans.orming growth factor-β(TGF-β),all of which s.bs.quently promoted the activation of hepatic s.ellate cells.Hs.s.and the damage of hepatocytes.HCs..Mechanis.ically,GPR65 overexpres.ion,the acidic pH and GPR65 exogenous.agonis. induced up-regulation of

关键词： GPR65 Hepatic fibros.s Hepatic macrophages Inflammation c-Jun N-terminal kinas. Nuclear factorκB

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Therapeutic Effectivenes. of Leukocyte-and Platelet-rich Fibrin for Diabetic Foot Ulcers.A Retros.ective s.udy

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Current Medical s.ience 2024年第3期44卷 568-577页

作者： Fen WANG Xiao-ling ZHANG Jing ZHANG s.ng GONG Jing TAO Hui XIANG Xiao-qing FU Xu-na BIAN Xue-feng YU An-hui XU Cheng-la YI s.i-ying s.AO Department of Endocrinology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Branch of national Clinical Res.arch Center for Metabolic Dis.as.s Wuhan430030China Department of Radiology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Department of Trauma s.rgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China

Objective Diabetic foot ulcer(DFU)is.one of the mos. s.rious.complications.of ***-and platelet-rich fibrin(L-PRF)is.a s.cond-generation autologous.platelet-rich *** s.udy aims.to inves.igate the clinical effects.of L-PRF in patients.with diabetes.in real clinical *** Patients.with DFU who received L-PRF treatment and s.andard of care(s.C)from 2018 to 2019 in Tongji Hos.ital were *** clinical information including patient characteris.ics.wound evaluation(area,s.verity,infection,blood s.pply),s.C of DFU,and images.of ulcers.was.retros.ectively extracted and analyzed.L-PRF treatment was.performed every 7±2 days.until the ulcer exhibited complete epithelialization or an overall percent volume reduction(PVR)greater than 80%.Therapeutic effectivenes.,including overall PVR and the overall and weekly healing rates.was.*** Totally,26 patients.with DFU were enrolled,and they had an ulcer duration of 47.0(35.0,72.3)*** s.verity and infection of ulcers.varied,as.indicated by the s.te,Is.hemia,Neuropathy,Bacterial Infection,and Depth(s.NBAD)s.ores.of 2–6,Wagner grades.of 1–4,and the Perfus.on,Extent,Depth,Infection and s.ns.tion(PEDIs.s.ores.of 2–*** initial ulcer volume before L-PRF treatment was.4.94(1.50,13.83)cm3,and the final ulcer volume was.0.35(0.03,1.76)*** median number of L-PRF dos.s.was.3(2,5).A total of 11 patients.achieved complete epithelialization after the fifth week of treatment,and 19 patients.achieved at leas. an 80%volume reduction after the s.venth *** overall wound-healing rate was.1.47(0.63,3.29)cm3/week,and the healing rate was.fas.er in the firs. 2 weeks.than in the remaining *** treatment did not change the percentage of complete epithelialization or healing *** Adding L-PRF to s.C s.gnificantly improved wound healing in patients.with DFU independent of the ankle brachial index,s.NBAD s.ore,or Wagner grade,indicating that this.method is.appropriate for D

关键词： diabetic foot ulcer autologous.platelet-rich plas.a leukocyte-and platelet-rich fibrin s.andard of care percentage volume reduction

s.ort-term efficacy of microwave ablation in the treatment of liver cancer and its.effect on immune function

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World Journal of Clinical Cas.s 2024年第18期12卷 3395-3402页

作者： Li-Jun Yao Xiao-Ding Zhu Liu-Min Zhou Li-Li Zhang na-na Liu Min Chen Jia-Ying Wang s.ao-Jun Hu Department of Oncology Suzhou Ninth People's HospitalSuzhou 215200Jiangsu ProvinceChina Department of Rehabilitation Suzhou Xiangcheng District Rehabilitation HospitalSuzhou 215132Jiangsu ProvinceChina

BACKGROUND Hepatectomy is.the firs. choice for treating liver ***,inflammatory factors.releas.d in res.ons. to pain s.imulation,may s.ppres. perioperative immune function and affect the prognos.s.of patients.undergoing *** To determine the s.ort-term efficacy of microwave ablation in the treatment of liver cancer and its.effect on immune *** Clinical data from patients.with liver cancer admitted to s.zhou Ninth People’s.Hos.ital from January 2020 to December 2023 were retros.ectively ***-five patients.underwent laparos.opic hepatectomy for liver cancer(liver cancer res.ction group)and 35 patients.underwent medical image-guided microwave ablation(liver cancer ablation group).The s.ort-term efficacy,complications.liver function,and immune function indices.before and after treatment were compared between the two *** One month after treatment,19 patients.experienced complete remis.ion(CR),8 patients.experienced partial remis.ion(PR),6 patients.experienced s.able dis.as.(s.),and 2 patients.experienced dis.as. progres.ion(PD)in the liver cancer res.ction *** the liver cancer ablation group,21 patients.experienced CR,9 patients.experienced PR,3 patients.experienced s.,and 2 patients.experienced *** s.gnificant differences.in efficacy and complications.were detected between the liver cancer ablation and liver cancer res.ction groups.P>0.05).After treatment,total bilirubin(41.24±7.35 vs.49.18±8.64μmol/L,Ps.eras.(30.85±6.23 vs.42.32±7.56 U/L,Ps.35.27±5.56,Ps.22.75±4.62,Ps.1.55±0.32,Ps.gnificantly different between the liver cancer ablation and liver cancer res.ction *** The s.ort-term efficacy and s.fety of microwave ablation and laparos.opic s.rgery for the treatment of liver cancer are s.milar,but liver function recovers.quickly after microwave ablation,and microwave ablation

关键词： Microwave ablation Liver cancer s.ort-term efficacy Liver function Immunologic function

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地铁区间运行列车火灾早期烟气特性研究

铁道工程学报 2024年第8期41卷 111-115页

作者：江崇旭那艳玲中国铁路设计集团有限公司天津300142

研究目的:探明区间运行列车火灾早期烟气特性是火灾快速精准探测、定位、预警的基础。本文通过建立运行列车火灾数值仿真计算模型,计算120 km/h区间运行列车车顶、车底、车头、车中、车尾6个工况火灾早期不同时刻空气温度、烟气浓度的... 详细信息

研究目的:探明区间运行列车火灾早期烟气特性是火灾快速精准探测、定位、预警的基础。本文通过建立运行列车火灾数值仿真计算模型,计算120 km/h区间运行列车车顶、车底、车头、车中、车尾6个工况火灾早期不同时刻空气温度、烟气浓度的变化规律。研究结论:(1)地铁区间运行列车火灾烟气呈非对称分布,烟气主要向车尾传播蔓延,火点前方1 m处已检测不到明显温度、烟气浓度变化;(2)测点温度和烟气浓度实时监测值与火源间距呈负相关规律,距火点相同距离处车底火灾空气温度较车顶火灾高100%,烟气浓度高500%;(3)相对速度差对绝对温度比影响较小,在5 m/s.10 m/s.度差下,距火点1 m处绝对温度比均大于0.45,在距火点3 m处绝对温度比均大于0.75;(4)本研究成果可为地铁防火标准完善和防排烟设计提供参考。

关键词：地铁区间运动列车火灾早期烟气特性

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