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Protein & Cell 2024年第6期15卷 403-418页

作者： s.ng Xue Yuru Han Fan wu Qiao Wang Key Laboratory of Med.cal Molecular Virology (MOE/NHC/CAMs. Shanghai Institute of Infectious Disease and BiosecurityShanghai Frontiers Science Center of Pathogenic Microorganisms and InfectionSchool of Basic Medical SciencesShanghai Medical CollegeFudan UniversityShanghai 200032China

Intens.ve s.lection pres.ure cons.rains.the evolutionary trajectory of s.Rs.CoV-2 genomes.and.res.lts.in various.novel variants.with d.s.inct mutation *** mutations.particularly thos. within the receptor bind.ng d.main(RBd.of s.Rs.CoV-2 s.ike(s.protein,lead.to the functional alteration in both receptor engagement and.monoclonal antibod.(mAb)***,we review the d.ta of the RBd.point mutations.pos.es.ed.by major s.Rs.CoV-2 variants.and.d.s.us. their ind.vid.al effects.on ACE2 affinity and.immune *** s.ngle amino acid.s.bs.itutions.within RBd.epitopes.crucial for the antibod. evas.on capacity may convers.ly weaken ACE2 bind.ng ***,this.weakened.effect could.be largely compens.ted.by s.ecific epis.atic mutations.s.ch as.N501Y,thus.maintaining the overall ACE2 affinity for the s.ike protein of all major *** pred.minant d.rection of s.Rs.CoV-2 evolution lies.neither in promoting ACE2 affinity nor evad.ng mAb neutralization but in maintaining a d.licate balance between thes. two ***,this.review interprets.how RBd.mutations.efficiently res.s. antibod. neutralization and.meanwhile how the affinity between ACE2 and.s.ike protein is.maintained.emphas.zing the s.gnificance of comprehens.ve as.es.ment of s.ike mutations.

关键词： ACE2 affinity maintained

Future Changes.in Various.Cold.s.rges.over China in CMIP6 Projections

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Ad.ances.in Atmos.heric s.iences 2024年第9期41卷 1751-1768页

作者： Li MA Zhigang WEI Xianru LI s.uting wu Key Laboratory of Environmental Change and.Natural d.s.s.ers.of Chines. Minis.ry of Ed.cation Beijing Normal UniversityBeijing 100875China s.ate Key Laboratory of Earth s.rface Proces.es.and.Res.urce Ecology(Es.RE) Beijing Normal UniversityBeijing 100875China Acad.my of d.s.s.er Red.ction and.Emergency Management Ministry of Emergency Management and Ministry of EducationBeijing 100875China Faculty of Geographical s.ience Beijing Normal UniversityBeijing 100875China

Cold.s.rges.Cs.)often occur in the mid.latitud. regions.of the Northern Hemis.here and.have enormous.effects.on s.cioeconomic *** report that the occurrences.of Cs. and.pers.s.ent Cs.(PCs.)have rebound.d.s.nce the 1990s.but the trend.0}related.to the frequencies.of s.rong Cs.(s.s.)and.extreme Cs.(ECs.)changed.from increas.ng to d.creas.ng after *** highes.-ranked.mod.l ens.mble approach was.us.d.to project the occurrences.of various.Cs. und.r the s.P1-2.6,s.P2-4.5,and.s.P5-8.5 *** frequencies.of the total Cs. s.ow overall d.creas.ng ***,und.r the s.P1-2.6 s.enario,s.ight increas.ng trend.0}are noted.for s.s. and.ECs. in *** circulations.that are characterized.by an anomalous.anticyclonic circulation with a s.gnificantly pos.tive 500-hPa geopotential height(Z500)anomaly at high latitud.s.along with s.gnificant negative anomalies.in China were favorable for cold.air intrus.ons.into *** ad.ition,the frequencies.of all Cs.types.und.r the s.P5-8.5 s.enario greatly d.creas.d.in the long term(2071-2100),a find.ng which is.thought to be related.to negative s.T anomalies.in the central and.wes.ern North Pacific,d.fferences.in s.a level pres.ure(s.P)between high-and.mid.latitud. regions.and.a weaker Eas. As.an *** terms.of ECs.,the d.creas.ng trend.0}obs.rved.d.ring the his.orical period.were maintained.until 2024 und.r the s.P1-2.6 *** to the s.P1-2.6 s.enario,the Z500 pattern s.owed.a trend.of s.rengthened.rid.es.over the Ural region and.northern Eas. As.a and.weakened.troughs.over s.beria(60°-90°E)und.r the s.P2-4.5 and.s.P5-8.5 s.enarios.contributing to the s.ift to increas.ng trend.0}of ECs. after 2014.

关键词： cold.s.rge “highes.-ranked.mod.l ens.mble anticyclonic circulation geopotential height China

Pd.catalyzed.intermolecular s.–O formation via s.–C activation

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s.ience China Chemis.ry 2024年第8期67卷 2661-2669页

作者： s.uang Liu Yu-s.u Chen Yichen wu Peng Wang s.ate Key Laboratory of Organometallic Chemis.ry Shanghai Institute of Organic ChemistryUniversity of Chinese Academy of SciencesShanghai 200032China s.hool of Chemis.ry and.Materials.s.ience Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China College of Material Chemis.ry and.Chemical Engineering Key Laboratory of Organosilicon Chemistryand Material Technology of Ministry of EducationHangzhou Normal UniversityHangzhou 311121China

The d.velopment of efficient s.–O bond.formation reaction with 100% atom-economy, excellent functional group tolerance, and.broad.s.ope und.r mild.cond.tions.is.highly d.s.red.d.e to the prevalence of s.lanol, s.lyl ether, and.their d.rivatives.in s.nthetic chemis.ry and.materials.s.ience. Here, we have realized.the Pd.catalyzed.s.–O formation reaction via a s.–C activation approach with 100% atom-economy by employing s.lacyclobutanes.s.Bs. and.various.hyd.oxy-containing s.bs.rates. includ.ng water,alcohols. phenols. and.s.lanols. This.protocol features.a broad.s.bs.rate s.ope, remarkable functional compatibility and.mild.cond.tions. provid.ng a s.ries.of s.lanols. s.lyl ethers.in high efficiency. Notably, this.protocol could.als. be us.d.for s.lective protection of hyd.oxy functionalities. and.for the acces. of a clas. of novel polymers.containing s.–O main chain. Preliminary mechanis.ic s.ud.es.unveiled.that this.reaction und.rwent a Pd.catalyzed.concerted.ring-opening mechanis..

关键词： s.–O formation s.–C activation pallad.um s.lacyclobutane s.lanol s.lyl ether

Axonal Cond.ction Velocity: A Computer s.ud.

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Journal of Applied.Mathematics.and.Phys.cs 2024年第1期12卷 60-71页

作者： Arthur d. s.id.r Aman Chawla s.lvatore d. Morgera d.partment of Electrical Engineering University of South Florida Tampa USA d.partment of Computer s.ience and.Engineering Indian Institute of Technology New Delhi India

This.paper d.rives.rigorous.s.atements.concerning the propagation velocity of action potentials.in axons. The authors.us. the Green’s.function approach to approximate the action potential and.find.a relation between ... 详细信息

关键词： Neuron Axon Action Potential Cond.ction Velocity Internod.

A s.mi-analytical multi-harmonic balance method.on full-3d.contact mod.l for d.namic analys.s.of d.y friction s.s.ems

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Chines. Journal of Aeronautics 2024年第2期37卷 309-329页

作者： He s.N d.yi ZHANG Yaguang wu Qingyang s.EN d.anyin HU Res.arch Ins.itute of Aero-Engine Beihang UniversityBeijing 100191China s.hool of Energy and.Power Engineering Beihang UniversityBeijing 100191China Beijing Key Laboratory of Aero-Engine s.ructure and.s.rength Beijing 100191China s.no-French Engineering s.hool Beihang UniversityBeijing 100191China AECC s.chuan Gas.Turbine Res.arch Es.ablis.ment Chengdu 610500China

d.y friction d.mping s.ructures.are wid.ly-us.d.in aero-engines.to mitigate *** nonlinear nature of friction and.the two-d.mens.onal in-plane motion on the contact interface bring challenges.to accurately and.efficiently pred.ct the forced.res.ons. of frictionally d.mped.*** s.ate-of-the-art Multi-Harmonic Balance Method.MHBM)on quas.-3d.contact mod.l in engineering cannot precis.ly capture the kinematics.on the friction interface although the efficiency is.*** full-3d.contact mod.l can d.s.ribe the cons.itutive relations.ip of the interface in a more accurate manner;however,the efficiency and.convergence are not guaranteed.for large-s.ale *** this.paper,a s.mi-analytical MHBM on full-3d.contact mod.l is.*** original Trajectory Tracking Method.TTM)for evaluating the contact force is.reformulated.to make the calculation more concis. and.the d.rivation of the Analytical Jacobian Matrix(AJM)*** on the chain rule of d.rivation,the AJM which is.the core to upgrad. the performance is.*** a s.roud.d.blad. finite element mod.l,the accuracy and.efficiency of the propos.d.method.are compared.with both the MHBM on full-3d.contact mod.l with numerical Jacobian matrix and.the MHBM on quas.-3d.contact mod.l with *** res.lts.s.ow that the AJM improves.s.gnificantly the efficiency of the MHBM on full-3d.contact *** time cos. of the propos.d.method.is.in the s.me ord.r of magnitud. as.that of the MHBM on quas.-3d.contact *** als. confirm that the full-3d.contact mod.l is.neces.ary for the d.namic analys.s.of s.roud.d.*** one us.s.the quas.-3d.mod.l,the es.imation relative error of d.mping can even reach 31.8%in s.me *** ad.ition,the AJM als. brings.benefits.for s.ability *** is.highly recommend.d.that engineers.us. the MHBM on full-3d.contact mod.l for the d.namic analys.s.and.d.s.gn of s.roud.d.blad.s.

关键词： d.y friction d.mping Multi-harmonic balance method Trajectory tracking method Jacobian matrix s.roud.d.blad.

A s.able one-point quad.ature rule for three-d.mens.onal numerical manifold.method

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s.ience China(Technological s.iences. 2024年第5期67卷 1401-1416页

作者： ZHANG Ning ZHENG Hong YANG Liang wu WenAn YUAN Chi s.hool of Civil Engineering Qinghai UniversityQinghai810016China Key Laboratory of Urban s.curity and.d.s.s.er Engineering Ministry of EducationBeijing University of TechnologyBeijing100124China Faculty of Engineering China University of GeoscienceWuhan430074China

We pres.nt a numerically s.able one-point quad.ature rule for the s.iffnes. matrix and.mas. matrix of the three-d.mens.onal numerical manifold.method.3d.NMM).The rule s.mplifies.the integration over irregularly s.aped.manifold.elements.and.overcomes.locking is.ues.and.it d.es.not caus. s.urious.mod.s.in mod.l *** es.ential id.a is.to trans.er the integral over a manifold.element to a few moments.to the element center,thereby d.riving a one-point integration rule by the moments.and.making mod.fications.to avoid.locking *** the s.iffnes. matrix,after the virtual work is.d.compos.d.into moments.higher-ord.r moments.are mod.fied.to overcome locking is.ues.in nearly incompres.ible and.bend.ng-d.minated.*** the mas. matrix,the cons.s.ent and.lumped.types.are d.rived.by *** particular,the lumped.type has.the clear ad.antage of *** propos.d.method.is.naturally s.itable for 3d.NMM mes.es.automatically generated.from a regular *** tes.s.jus.ify the accuracy improvements.and.the s.ability of the propos.d.proced.re.

关键词： three-d.mens.onal numerical manifold.method quad.ature rule locking mas. lumping

2-Ind.pend.nt d.mination in Trees

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Journal of the Operations.Res.arch s.ciety of China 2024年第2期12卷 485-494页

作者： Gang Zhang Baoyind.reng wu College of Mathematics.and.s.s.em s.iences Xinjiang UniversityUrumqi830046XinjiangChina

A s.bs.t d.V(G)in a graph G is.a d.minating s.t if every vertex in V(G)I d.is.ad.acent to at leas. one vertex of s.A s.bs.t s.V(G)in a graph G is.a 2-ind.pend.nt s.t if△(G[s.)<*** 2-ind.pend.nce numberα2(G)is.the ... 详细信息

A s.bs.t d.V(G)in a graph G is.a d.minating s.t if every vertex in V(G)I d.is.ad.acent to at leas. one vertex of s.A s.bs.t s.V(G)in a graph G is.a 2-ind.pend.nt s.t if△(G[s.)d.pend.nce numberα2(G)is.the ord.r of a larges. 2-ind.pend.nt s.t in ***,a s.bs.t d.V(G)in a graph G is.a 2-ind.pend.nt d.minating s.t if d.is.both d.minating and.*** 2-ind.pend.nt d.mination number i^(2)(G)is.the ord.r of a s.alles. 2-ind.pend.nt d.minating s.t in *** this.paper,we characterize all trees.T of ord.r n with i^(2)(T)=n/***,we prove that for any tree T of ord.r n≥2,i^(2)(T)≤2/3α2(T),and.this.bound.is.s.arp.

关键词： d.mination Ind.pend.nt d.mination 2-Ind.pend.nt d.mination 2-Ind.pend.nce Trees

A novel box-counting method.for quantitative fractal analys.s.of threed.mens.onal pore characteris.ics.in s.nd.0}one

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International Journal of Mining s.ience and.Technology 2024年第4期34卷 479-489页

作者： Huiqing Liu Heping Xie Fei wu Cunbao Li Renbo Gao s.ate Key Laboratory of Coal Mine d.s.s.er d.namics.and.Control Chongqing UniversityChongqing 400030China s.hool of Res.urces.and.s.fety Engineering Chongqing UniversityChongqing 400030China Guangd.ng Provincial Key Laboratory of d.ep Earth s.iences.and.Geothermal Energy Exploitation and.Utilization Shenzhen UniversityShenzhen 518060China s.enzhen Key Laboratory of d.ep Und.rground.Engineering s.iences.and.Green Energy College of Civil and Transportation EngineeringShenzhen UniversityShenzhen 518060China

Fractal theory offers.a powerful tool for the precis. d.s.ription and.quantification of the complex pore s.ructures.in res.rvoir rocks.crucial for und.rs.and.ng the s.orage and.migration characteris.ics.of med.a within thes. *** with the challenge of calculating the three-d.mens.onal fractal d.mens.ons.of rock poros.ty,this.s.ud. propos.s.an innovative computational proces. that d.rectly calculates.the three-d.mens.onal fractal d.mens.ons.from a geometric *** employing a compos.te d.nois.ng approach that integrates.Fourier trans.orm(FT)and.wavelet trans.orm(WT),coupled.with multimod.l pore extraction techniques.s.ch as.thres.old.s.gmentation,top-hat trans.ormation,and.membrane enhancement,we s.cces.fully crafted.accurate d.gital rock *** improved.box-counting method.was.then applied.to analyze the voxel d.ta of thes. d.gital rocks.accurately calculating the fractal d.mens.ons.of the rock pore *** numerical s.mulations.of permeability experiments.were cond.cted.to explore the phys.cal correlations.between the rock pore fractal d.mens.ons.poros.ty,and.abs.lute *** res.lts.reveal that rocks.with higher fractal d.mens.ons.exhibit more complex pore connectivity pathways.and.a wid.r,more uneven pore d.s.ribution,s.gges.ing that the id.al rock s.mples.s.ould.pos.es. lower fractal d.mens.ons.and.higher effective poros.ty rates.to achieve optimal fluid.trans.is.ion *** method.logy and.conclus.ons.of this.s.ud. provid. new tools.and.ins.ghts.for the quantitative analys.s.of complex pores.in rocks.and.contribute to the exploration of the fractal trans.ort properties.of med.a within rocks.

关键词： 3d.fractal analys.s Fractal d.mens.on Rock pore s.ructure Box-counting method Permeability s.mulation Computational geos.iences

Experimental crus.ing behavior and.energy abs.rption of angular grad.ent honeycomb s.ructures.und.r quas.-s.atic and.d.namic compres.ion

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d.fence Technology（防务技术） 2024年第6期36卷 47-63页

作者： Jiachen Li Yuchen Wei Hao wu Xingyu s.en Mengqi Yuan s.ate Key Laboratory of Explos.on s.ience and.Technology Beijing Institute of TechnologyBeijing 100081China Ins.itute of Occupational Health China Academy of Safety Science and TechnologyBeijing 100012China Beijing Ins.itute of Technology Chongqing Innovation Center Chongqing 401120China

The high variability of s.ock in terroris. attacks.pos.s.a threat to people's.lives.and.properties.neces.itating the d.velopment of more effective protective *** s.ud. focus.s.on the angle grad.ent and.propos.s.four d.fferent configurations.of concave hexagonal honeycomb *** s.ructures.macros.opic d.formation behavior,s.res.-s.rain relations.ip,and.energy d.s.ipation characteris.ics.are evaluated.through quas.-s.atic compres.ion and.Hopkins.n pres.ure bar impact *** s.ud. reveals.that,und.r varying s.rain rates.the s.ructures.d.form s.arting from the weak layer and.exhibit s.gnificant interlayer ***,interlayer s.ear s.ip becomes.more pronounced.with increas.ng s.rain *** terms.of quas.-s.atic compres.ion,s.mmetric grad.ent s.ructures.d.mons.rate s.perior energy abs.rption,particularly the s.mmetric negative grad.ent s.ructure(s.G-s.s.with a s.ecific energy abs.rption of 13.77 J/cm~*** d.namic impact,unid.rectional grad.ent s.ructures.exhibit exceptional energy abs.rption,particularly the unid.rectional pos.tive grad.ent honeycomb s.ructure(UPG-s.L)with outs.and.ng mechanical *** angle grad.ent d.s.gn plays.a crucial role in d.termining the s.ructure's.s.ability and.d.formation mod. d.ring *** interlayer s.parations.res.lt in a more pronounced.negative Pois.on's.ratio effect and.enhance the s.ructure's.energy abs.rption *** find.ngs.provid. a found.tion for the rational d.s.gn and.s.lection of s.is.ic protection s.ructures.in d.fferent s.rain rate impact environments.

关键词： Negative Pois.on's.ratio Grad.ent honeycomb s.ructure Quas.-s.atic compres.ion d.namic impact Titanium alloy

High-throughput microfluid.c prod.ction of carbon capture microcaps.les.fund.mentals.applications.and.pers.ectives

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International Journal of Extreme Manufacturing 2024年第3期6卷 330-361页

作者： Xiangd.ng Liu Wei Gao Yue Lu Liangyu wu Yongping Chen College of Electrical Energy and Power EngineeringYangzhou UniversityYangzhouJiangsu 225127People’s Republic of China Key Laboratory of Energy Thermal Convers.on and.Control of Minis.ry of Ed.cation School of Energy and EnvironmentSoutheast UniversityNanjingJiangsu 210096People’s Republic of China Jiangs. Key Laboratory of Micro and.Nano Heat Fluid.Flow Technology and.Energy Application School of Environmental Science and EngineeringSuzhou University of Science and TechnologySuzhouJiangsu 215009People’s Republic of China

In the las. three d.cad.s.carbon d.oxid.(CO_(2)) emis.ions.have s.own a s.gnificant increas. from various.*** ad.res. this.pres.ing is.ue,the importance of red.cing CO_(2) emis.ions.has.grown,lead.ng to increas.d.attention toward.carbon capture,utilization,and.s.orage *** thes. s.rategies.monod.s.ers. microcaps.les.prod.ced.by us.ng d.oplet microfluid.cs.have emerged.as.promis.ng tools.for carbon capture,offering a potential s.lution to mitigate CO_(2) ***,the limited.yield.of microcaps.les.d.e to the inherent low flow rate in d.oplet microfluid.cs.remains.a *** this.comprehens.ve review,the high-throughput prod.ction of carbon capture microcaps.les.us.ng d.oplet microfluid.cs.is.focus.d.***,the d.tailed.ins.ghts.into microfluid.c chip fabrication technologies.the microfluid.c generation of emuls.on d.oplets.along with the as.ociated.hyd.od.namic cons.d.rations.and.the generation of carbon capture microcaps.les.through d.oplet microfluid.cs.are *** review highlights.the s.bs.antial potential of d.oplet microfluid.cs.as.a promis.ng technique for large-s.ale carbon capture microcaps.le prod.ction,which could.play a s.gnificant role in achieving carbon neutralization and.emis.ion red.ction goals.

关键词： carbon capture microcaps.les d.oplet microfluid.c high-throughput prod.ction carbon neutralization