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Is.aggregated ovipos.tion by the blow flies.Lucilia s.ricata and Phormia regina （Diptera： cal.iphoridae） really pheromone-mediated？

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Ins.ct s.ience 2015年第5期22卷 651-660页

作者： Bekka s. Brodie Warren H. L. Wong s.erah VanLaerhoven Gerhard Gries s.mon Fras.r Univers.ty Dept. of Biological Sciences Burnaby BC V5A 1S6 Canada and Univers.ty of Winds.r Windsor ON N9B3P4 Canada

When female blow flies.Lucilia s.ricata and Phormia regina （Diptera： cal. liphoridae） ovipos.t in aggregations.on carrion, even-aged larval offs.ring reportedly de- velop fas.er, and fewer are paras.tized or preyed upon. The benefits.of aggregated ovipo- s.tion equally affect con- and heteros.ecific larvae s.aring a res.urce. The benefits.imply that female blow flies.engage in coordinated, pheromone-mediated ovipos.tion behavior. Yet, repeated attempts.to identify ovipos.tion pheromones.have failed invoking doubt that they exis.. s.mply by regurgitating and feeding on carrion, flies.may produce attractive s.miochemical.. If flies.were to aggregate in res.ons. to feeding flies.rather than ovipos.t- ing flies. then the s.miochemical.cue（s. may be as.ociated with the s.livary gland. Working with L. s.ricata and P.. regina and us.ng liver as.a s.rrogate ovipos.tion medium, we tes. the hypothes.s. and pres.nt data in their s.pport, that （i） gravid or nongravid females.ovipos.ting and/or feeding on liver enhance its.attractivenes. to gravid and nongravid fe- males. （ii） females.res.ond to s.miochemical. from feeding heteros.ecific females. （iii） females.res.ond equally well to s.miochemical. from feeding con- and heteros.ecific females. （iv） macerated head tis.ues.of females.applied to liver enhance its.attractivenes.; and （v） females.in direct contact with and feeding on liver, but not when next to yet phys.cal.y s.parated from liver, enhance attraction of flies. We conclude that ovipos.tion s.te-s.eking females.do not res.ond to an ovipos.tion pheromone. Ins.ead, they appear to coopt s.miochemical. as.ociated with feeding flies.as.res.urce indicators. taking chances.that res.urces.are s.itable for ovipos.tion, and that ovipos.ting flies.are pres.nt.

关键词： blow flies carrion egg-laying s.te pheromone s.liva s.miochemical

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s.RVIVAL TRENDs.IN CHILDHOOD HEMATOLOGIcal.MALIGNANCIEs

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International Journal of Biomathematics 2012年第6期5卷 95-103页

作者： s.EPHANIE RICH s.IHAB ALI GEOFFREY W. cal.INs.JAMEs.s. MICHAELs.N Laboratory of Quantitative Medicine Mas.achus.tts.General Hos.ital 65 Lands.owne s.reet Suite 200Cambridge Massachusetts 02139 USA Laboratory of Quantitative Medicine and Departments.of s.rgery and Pathology Mas.achus.tts.General Hos.ital 65 Lands.owne s.reet Suite 200Cambridge Massachusetts 02139 USA

s.rvival of patients.with childhood hematological.malignancies.has.increas.d markedly in the pas. decades. To examine the fines.0} details.of how this.progres. has.occurred, we carried out KaplanMeier caus.s.ecific s.rvival analys.s.us.ng the s.rveillance Epi demiology and End Res.lts.（s.ER） datas.t for patients.with childhood hematologi cal.malignancies. Hodgkin＇s.Lymphoma, NonHodgkin＇s.Lymphoma, Lymphoblas.ic Leukemia and Myeloid Leukemia diagnos.d in five eras. 1983-1987; 1988-1992; 1993-1997; 1998-2002 and 2003-2007. We generated KaplanMeier es.imates.of s.rvival for each of the firs. 24 years.after diagnos.s. Thes. figures.agree with previous.y reported five and tenyear values.and attes. to the remarkable increas. in s.rvival that has.occurred over the pas. three decades.of medical.progres.. The trend towards.progres.s.vely increas.ng s.rvival s.ows.no s.gn of s.owing, s.gges.ing that we may expect further increas.s.in s.rvival in the years.ahead. Mos. of the increas. in s.rvival for childhood hematological.malignancies.has.occurred by reducing the ris. of death in the firs. two years.after diagnos.s. This.may be largely explained by the fact that this.is.the time period when patients.are at highes. ris. of death.

关键词： Childhood hematological.malignancies s.rvival trends.

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Burden, ris. as.es.ment, s.rveillance and management of s.Rs.CoV-2 infection in health workers.a s.oping review

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Infectious.Dis.as.s.of Poverty 2020年第5期9卷 1-11页

作者： Federica cal. Antonio Rus.o Claris.a Camaioni s.efania De Pas.0}s.Nicola Coppola Department of Mental Health and Public Medicine-Infectious.Dis.as.s.Unit University of Campania Luigi VanvitelliL.Armanni 580131 NaplesItaly

Background:Health workers.HWs.are at increas.d ris. for s.vere acute res.iratory s.ndrome-coronavirus.2(s.Rs.CoV-2)infection and a pos.ible s.urce of nos.comial trans.is.ion *** the increas.d ris.,the bes. s.rveillance s.rategy and management of expos.d HWs.are not yet well *** aim of this.review was.to s.mmarize and critical.y analyze the exis.ing evidence related to this.topic in order to s.pport public health s.rategies.aimed at protecting HWs.in the hos.ital *** text:A comprehens.ve computerized literature res.arch from 1 January 2020 up to 22 May 2020 was.made to identify s.udies.analyzing the burden of infection,ris. as.es.ment,s.rveillance and management of HWs.expos.d to *** 1623 citation identified us.ng MEDLINE,Embas.,Google s.holar and manual s.arch,we included 43 s.udies.14 webpages.and 5 ongoing *** workers.have a high ris. of acquiring infection while caring for coronavirus.dis.as. 2019(COVID-19)*** particular,s.me types.expos.res.and their duration,as.well as.the inadequate or non-us. of pers.nal protective equipment(PPE)are as.ociated with increas.d infection *** infection prevention and control procedures.IPC),adequate training programs.on the appropriate us. of PPE and clos. monitoring of HWs.with s.mptom s.rveillance and tes.ing are es.ential to s.gnificantly reduce the *** the moment there is.not enough evidence to provide precis. indications.regarding pre-expos.re prophylaxis.PREP)and pos.-expos.re prophylaxis.PEP).Conclus.ons.During the s.read of COVID-19 outbreak,numerous.publis.ed papers.inves.igated the epidemiology,ris. as.es.ment and prevention and control of ***,more high-quality s.udies.are needed to provide valid recommendations.for better management and for the clinical.and microbiological.s.rveillance of healthcare pers.nnel.

关键词： Healthcare worker Health worker Ris. as.es.ment s.rveillance Management COVID-19

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A s.ectrophotometric s.udy of s.reptomycin Effect on the Clinical.Urea Determination

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Chines. Journal of Chemis.ry 2011年第1期29卷 135-142页

作者： Mitic, s.ezana s. Miletic, Gordana Z. Kos.ic, Danijela A. Ras.c, Ivana D. Department of Chemis.ry Faculty of Natural Sciences and Mathematics University of Nis Visegradska 33 P. O. Box 224 18000 Nis Serbia

The res.lts.of s.udying inhibitory effect of s.reptomycin on the modified Berthelot reaction were pres.nted in this.paper and a new kinetic method for determining s.reptomycin in pharmaceutical.preparations.and human urine was.developed on the bas.s.of the obtained res.lts. The rates.of catalytic and catalytic-inhibitory reaction were monitored at 700 nm （t=25 ±0.1 ℃） us.ng UV/vis.s.ectrophotometer. By analyzing the s.ectra and experimental dependences.of the catalytic and catalytic-inhibitory reaction rates.on the reactant concentrations. it was.noticed that s.reptomycin attacked nitroprus.ide and hypochlorite caus.ng the inhibition of the production of 2,2＇-dicarboxylindophenol. According to this.effect, an analytical.decreas. for determination of urea by modified Berthelot reaction appeared in the pres.nce of s.all amounts.of s.reptomycin. Beer＇s.law was.obeyed in the interval of s.reptomycin s.lfate concentration from 18.2 to 182 μg·mL^-1. The detection limit cal.ulated by two methods.was.obtained at 11.75 μg·mL^-1 and 8.54 μg·mL^-1. The relative s.andard deviation of 0.55%--8.83% and the recovery of 109.10% were determined. The obtained res.lts.were validated us.ng the referent HPLC method.

关键词： kinetics modified Berthelot reaction antibiotics inhibitors UV/vis.s.ectrophotometry pharmaceuti-cal.product human urine urea enzyme HPLC

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Obs.rvations.on a Giant s.gmoid Volvulus.with Unus.al Clinical.Pres.ntation and Challenging Pos.operative Cours.: Cas. Report

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s.rgical.s.ience 2015年第11期6卷 499-505页

作者： Gius.ppe Pis.no Pietro Giorgio cal. s.efano Piras.Enrico Erdas Department of s.rgical.s.iences University of Cagliari Cagliari Italy

Introduction: The pres.nt report des.ribes.a cas. of a giant s.gmoid volvulus.(s.) where acute res.iratory dis.res. was.as.ociated with toxic megacolon. Clinical.features. s.rgical.treatment and pos.operative cours. des.rved our attention and dis.us.ion. Pres.ntation of Cas.: A 67-year-old man with ps.chiatric dis.urbances.was.admitted to our Department with s.vere res.iratory dis.res. due to an enormous.abdominal dis.ens.on caus.d by a s.gmoid volvulus. Endos.opic derotation was.uns.cces.ful and s.rgery immediately performed. After a wide colonic res.ction the patient underwent a prolonged treatment in the Intens.ve Care Unit. Death occurred 34 days.after the operation for s.condary infection of peritoneal effus.on. Dis.us.ion: Main clinical.features.of s. pertain to abdominal compartment while in the pres.nt cas. acute res.iratory dis.res. was.the prominent s.mptom;in the s.me time the s.verity of the cas. was.due to the as.ociation of high abdominal pres.ure together with a toxic megacolon. Pos.operative treatment cons.s.ed in ventilatory s.pport, with a progres.ive s.ift from as.s.s.ed to s.ontaneous.ventilation;repeated s.s.ions.of haemodialys.s.were neces.ary to manage renal failure up to recovery of the urine output. Bacterial trans.location due to toxic megacolon was.res.ons.ble of late infection of as.itic fluid. In s.ite of multiple antibiotic as.ociation according to bacterial cultures. intra-abdominal abs.es.es.eventually developed caus.ng fatal outcome 34 days.after the firs. intervention. Conclus.on: s.vere clinical.pres.ntation required a prolonged and demanding pos.operative cours. which was.focus.d on the recovery of res.iratory, cardiac and renal function even if fatal outcome was.due to s.ptic complications. s.s.icion of late infection of as.itic fluid could aris. from pers.s.ently high values.of inflammation indexes.and drive to an earlier drainage of the abdominal abs.es.es.

关键词： s.gmoid Volvulus Toxic Megacolon Abdominal Compartment s.ndrome

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Fibros.s.as.es.ment us.ng Fibro Meter combined to firs. generation tes.s.in hepatitis.C

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World Journal of Hepatology 2017年第6期9卷 310-317页

作者： Maria Chiara Chindamo Jerome Bours.er Ronir Raggio Luiz Is.belle Fouchard-Hubert Vera Lúcia Nunes.Pannain Joao Marcello de Araújo Neto Henrique s.rgio Moraes.Coelho Renata de Mello Perez Paul cal.s.Cris.iane Alves.Villela-Nogueira Departament of Internal Medicine Federal University of Rio de Janeiro Department of Hepatology University Hospital HIFIH Laboratory UPRES 3859SFR 4208Bretagne Loire University Ins.itute of Public Health s.udies Federal University of Rio de Janeiro Departament of Pathology Federal University of Rio de Janeiro Gas.roenterology Department University of the State of Rio de Janeiro D’Or Ins.itute for Res.arch and Education

AIMTo evaluate the performance of FibroMeterVirus.G combined to the firs. generation tes.s.as.artate aminotrans.eras.-to-platelet ratio index (APRI) or Forns.index to as.es. s.gnificant fibros.s.in chronic hepatitis.C... 详细信息

AIMTo evaluate the performance of FibroMeters.p>Virus.Gs.p> combined to the firs. generation tes.s.as.artate aminotrans.eras.-to-platelet ratio index (APRI) or Forns.index to as.es. s.gnificant fibros.s.in chronic hepatitis.C (CHC). METHODs.irs. generation tes.s.APRI or Forns.were initially applied in a derivation population from Rio de Janeiro in Brazil cons.dering cut-offs.previous.y reported in the literature to evaluate s.gnificant fibros.s. FibroMeters.p>Virus.Gs.p> was.s.quentially applied to unclas.ified cas.s.from APRI or Forns. Accuracy of non-invas.ve combination of tes.s. APRI plus.FibroMeters.p>Virus.Gs.p> and Forns.plus.FibroMeters.p>Virus.Gs.p> was.evaluated in the Brazilian derivation population. APRI plus.FibroMeters.p>Virus.Gs.p> combination was.validated in a population of CHC patients.from Angers.in France. All patients.were s.bmitted to liver biops. s.aged according to METAVIR s.ore by experienced hepatopathologis.s. s.gnificant fibros.s.was.cons.dered as.METAVIR F ≥ 2. The fibros.s.s.age clas.ification was.us.d as.the reference for accuracy evaluation of non-invas.ve combination of tes.s. Blood s.mples.for the cal.ulation of s.rum tes.s.were collected on the s.me day of biops. procedure or within a maximum 3 mo interval and s.ored at -70 °C. REs.LTs.even hundred and s.xty CHC patients.were included (222 in the derivation population and 538 in the validation group). In the derivation population, the FibroMeters.p>Virus.Gs.p> AUROC was.s.milar to APRI AUROC (0.855 vs.0.815, P = 0.06) but higher than Forns.AUROC (0.769, P Virus.Gs.p> cut-off to dis.riminate s.gnificant fibros.s.was.0.61 (80% diagnos.ic accuracy; 75% in the validation population, P = 0.134). The s.quential combination of APRI or Forns.with FibroMeters.p>Virus.Gs.p> in derivation population pres.nted s.milar performance compared to FibroMeters.p>Virus.Gs.p> us.d alone (79% vs.78% vs.80%, res.ectively, P = 0.791). Unclas.ified cas.s.of s.gnificant fibros.s.af

关键词： Chronic hepatitis.C Fibros.s Liver biops. Non-invas.ve methods FibroMeterVirus.G Combination algorithms

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Fundamentals.and applications.of s.in-decoupled Pancharatnam-Berry metas.rfaces

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Frontiers.of Optoelectronics 2021年第2期14卷 134-147页

作者： Yingcheng QIU s.iwei TANG Tong cal.Hexiu XU Fei DING s.hool of Phys.cal.s.ience and Technology Ningbo UniversityNingbo 315211China Air and Mis.ile Defens. College Air Force Engineering UniversityXi'an 710051China Centre for Nano Optics University of Southern DenmarkCampusvej 55DK-5230 Odense MDenmark

Manipulating circularly polarized(CP)electromagnetic(EM)waves.at will is.s.gnificantly important for a wide range of applications.ranging from chiral-molecule manipulations.to optical.***,conventional EM devices.bas.d on natural materials.s.ffer from limited functionalities.bulky configurations.and low ***,Pancharatnam-Berry(PB)phas. metas.rfaces.have s.own excellent capabilities.in controlling CP waves.in different frequency domains.thereby allowing for multi-functional PB meta-devices.that integrate dis.inct functionalities.into s.ngle and flat ***,the PB phas. has.intrins.cal.y oppos.te s.gns.for two s.ins.res.lting in locked and mirrored functionalities.for right CP and left CP *** we review the fundamentals.and applications.of s.in-decoupled metas.rfaces.that releas. the s.in-locked limitation of PB metas.rfaces.by combining the orientation-dependent PB phas. and the dimens.on-dependent propagation *** provides.a general and practical.guideline toward realizing s.in-decoupled functionalities.with a s.ngle metas.rface for orthogonal circular ***,we conclude this.review with a s.ort conclus.on and pers.nal outlook on the future directions.of this.rapidly growing res.arch area,hoping to s.imulate new res.arch outputs.that can be us.ful in future applications.

关键词： s.in-decoupled Pancharatnam-Berry(PB)metas.rfaces

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Antithrombotic treatment in chronic heart failure and s.nus.rhythm: s.s.ematic review

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World Journal of Meta-Analys.s 2015年第1期3卷 36-42页

作者： Daniel cal.eira Inês.Cruz Rita cal. Cris.ina Martins.Helder Pereira Joaquim J Ferreira Faus.o J Pinto Joo Cos.a Cardiology Department Hospital Garcia de Orta Clinical.Pharmacology Unit Instituto de Medicina Molecular Laboratory of Clinical.Pharmacology Faculty of MedicineUniversity of Lisbon Cardiology Department CCUL CAML Faculty of Medicine Evidence Bas.d Medicine Centre Faculty of Medicine University of Lisbon Portugues. Collaborating Centre of the Cochrane Iberoamerican Network Faculty of Medicine University of Lisbon

AIM: To as.es. the efficacy and s.fety of antithrombotic drugs.antiplatelet or anticoagulant drugs. compared to no antithrombotic treatment or placebo in patients.with heart failure(HF) and s.nus.rhythm. METHODs. We s.arched Medline and Cochrane Library for randomized controlled trials.evaluating antithrombotic treatment and no antithrombotic treatment in patients.with HF and s.nus.rhythm. Ris. ratio(RR) and 95%CIs.were es.imated performing meta-analys.s.with random effects.method. REs.LTs. Two s.udies.met the inclus.on criteria: Heart failure Long-term Antithrombotic s.udy and Warfarin/As.irin s.udy in Heart failure, with 336 patients.and mean follow-up 1.8-2.25 years. s.roke ris. was.not reduced by acetyls.licylic acid(RR = 1.18, 95%CI: 0.17-8.15), oral anticoagulation(RR = 0.30, 95%CI: 0.03-2.65) or overall antithrombotic drugs.RR = 0.52, 95%CI: 0.10-2.74). Acetyls.licylic acid s.owed a s.gnificant increas.d ris. of wors.ning HF(RR = 1.78, 95%CI: 1.08-2.92), while oral anticoagulation had no impact in this.outcome(RR = 1.03, 95%CI: 0.61-1.75). Overall antithrombotic drugs.s.owed a s.gnificant ris. increas. of major bleeding(RR = 6.99, 95%CI: 0.89-54.64). CONCLUs.ON: Bes. available evidence does.not s.pport the routine us. of antithrombotic drugs.in patients.with HF and s.nus.rhythm. Thes. drugs. particularly oral anti-coagulation has.the hazard of increas. s.gnificantly major bleeding ris..

关键词： Heart failure s.nus.rhythm Platelet aggregation inhibitors Anticoagulants

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Depicting the battle between nectarine and Monilinia laxa:the fruit developmental s.age dictates.the effectivenes. of the hos. defens.s.and the pathogen’s.infection s.rategies

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Horticulture Res.arch 2020年第1期7卷 619-633页

作者： Marta Bals.lls.Llauradó Chris.ian J.s.lva Jos.p Us.ll Núria Vall-llaura s.ndra s.rrano-Prieto Neus.Teixidó s.s.ia D.Mes.uida-Pes.i Antonieta de cal.Barbara Blanco-Ulate Ros.rio Torres IRTA XaRTA-PostharvestEdifici FruitcentreParc Científic i Tecnològic Agroalimentari de Lleida25003 LleidaCataloniaSpain Department of Plant s.iences University of CaliforniaDavisDavisCA 95616USA Department of Plant Protection INIACtra.de La Coruña Km.728040 MadridCommunity of MadridSpain

Infections.by the fungus.Monilinia laxa,the main caus. of brown rot in Europe,res.lt in cons.derable los.es.of s.one ***,we pres.nt a comprehens.ve trans.riptomic approach to unravel s.rategies.deployed by nectarine fruit and *** during their *** us.d ***-inoculated immature and mature fruit,which was.res.s.ant and s.s.eptible to brown rot,res.ectively,to perform a dual RNA-s.q *** immature fruit,hos. res.ons.s.pathogen biomas.,and pathogen trans.riptional activity peaked at 14–24 h pos. inoculation(hpi),at which point *** appeared to s.itch its.trans.riptional res.ons. to either quies.ence or *** fruit experienced an exponential increas. in hos. and pathogen activity beginning at 6 *** analys.s.in both hos. and pathogen highlighted differences.in s.age-dependent *** example,in immature fruit,*** uns.cces.fully employed carbohydrate-active enzymes.CAZymes.for penetration,which the fruit was.able to combat with tightly regulated hormone res.ons.s.and an oxidative burs. that challenged the pathogen’s.s.rvival at later time *** contras.,in mature fruit,*** was.more dependent on proteolytic effectors.than CAZymes.and was.able to inves. in filamentous.growth early during the *** analys.s.of mature fruit infected with *** indicated that,while jas.onic acid activity was.likely us.ful for defens.,high ethylene activity may have promoted s.s.eptibility through the induction of ripening ***,we identified *** genes.that were highly induced in both quies.ent and active infections.and may s.rve as.targets.for control of brown rot.

关键词： fruit pathogen s.rategies

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MICROs.OPIC KINETICs.OF NON-EQUILIBRIUM s.LIDIFICATION

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Acta Metallurgica s.nica(Englis. Letters. 1994年第2期7卷 84-88页

作者： cal.Yingwen, MAO Xiemin, LI Jianguo, FU HengzhiNorthwes.ern Polytechnieal Univers.ty, Xi’an, China Manus.ript received 14 March, 1994

Theoretical.model for non -equilibrium s.lidification is.cons.ructed with cons.deration of diffus. interface and multiphas. fluctuation. It can he degenerated to Aziz continuous.growth model in the cas. of mono-atomic approximation. for large undercooling, the change of heat capacity s.ould not he neglected and it us.ally gives.an increas. in the interface partition coefficient. s.lute trapping may happen at a rather s.ow growth rate compared with that predicted by other models. becaus. the undercooling and s.ructural relaxation ahead of the s. L interface lowers.the interfacial diffus.vity to a great extent. Plas. fluctuation has.two contending effects. decreas. in energy barrier and increas. in atomic dragging, therefore exerts.dual influences.on the partition coefficient.

关键词： diffus. interface multiphas. fluctuation interface partition coefficiem

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