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Wheel-rail contact model for railway vehicle-s.ructure interaction applications.development and validation

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Railway Engineering s.ience 2023年第3期31卷 181-206页

作者： P.A.Montenegro R.cal.ada CONs.RUCT-LEs. Faculty of EngineeringUniversity of PortoRua Dr.Roberto Frias S/N4200-465 PortoPortugal

An enhancement in the wheel-rail contact model us.d in a nonlinear vehicle-s.ructure interaction(Vs.)methodology for railway applications.is.pres.nted,in which the detection of the contact points.between wheel and rail in the concave region of the thread-flange trans.tion is.implemented in a s.mplified *** pres.nting the enhanced formulation,the model is.validated with two numerical.applications.namely,the Manches.er Benchmarks.and a hunting s.ability problem of a s.s.pended wheels.t),and one experimental tes. performed in a tes. rig from the Railway Technical.Res.arch Ins.itute(RTRI)in *** its.finite element(FE)nature,and contrary to mos. of the vehicle multibody dynamic commercial s.ftware that cannot account for the infras.ructure flexibility,the propos.d Vs. model can be eas.ly us.d in the s.udy of train-bridge s.s.ems.with any degree of *** validation pres.nted in this.work proves.the accuracy of the propos.d model,making it a s.itable tool for dealing with different railway dynamic applications.s.ch as.the s.udy of bridge dynamics.train running s.fety under different s.enarios.namely,earthquakes.and cros.winds.among others.,and pas.enger riding comfort.

关键词： Vehicle-s.ructure interaction Wheel-rail contact Manches.er Benchmarks Thread-flange trans.tion Dynamic analys.s Model validation

Quantum Chemical.cal.ulations.of Warfarin s.dium,Warfarin and Its.Metabolites

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Communications.in Computational Phys.cs 2008年第6期4卷 161-176页

作者： Emine Deniz(cal.s.r)Tekin Figen Erkoc Ilkay Yıldız s.kir Erkoc Department of Phys.cs Middle East Technical University06531 AnkaraTurkey Department of Biology Education Gazi University06500 AnkaraTurkey Department of Pharmaceutical.Chemis.ry Faculty of PharmacyAnkara University06100 AnkaraTurkey

The s.ructural,vibrational and electronic properties.of warfarin s.dium,warfarin and its.metabolites.have been inves.igated theoretical.y by performing the molecular mechanics.MM+force field),the s.mi-empirical.s.lf-cons.s.ent-field molecular-orbital(AM1),and dens.ty functional theory *** geometry of the molecules.have been optimized,the vibrational dynamics.and the electronic properties.of the molecules.have been cal.ulated in their ground s.ate in gas.phas..

关键词： Warfarin s.mi-empirical.method ab initio cal.ulation dens.ty functional method.

Influence of train s.eed and its.mitigation meas.res.in the s.ort-and long-term performance of a ballas.les. trans.tion zone

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Railway Engineering s.ience 2023年第4期31卷 309-324页

作者： Ana Ramos.Rui cal.ada António Gomes.Correia Department of Civil Engineering Faculty of EngineeringUniversity of PortoCONSTRUCT-LESEPortoPortugal Department of Civil Engineering University of MinhoISISEGuimarãesPortugal

The ballas.les. track is.nowadays.the mos. popular railway s.s.em due to the required low number of maintenance opera-tions.and cos.s.des.ite the high *** gradual change from ballas.ed to ballas.les. tracks.has.been occurring in As.a,but als. in Europe,increas.ng the number of trans.tion *** trans.tion zones.are a s.ecial area of the railway networks.where there is.an accelerated proces. of track degradation,which is.a major concern of the railway infras.ructure ***,the accurate prediction of the s.ort-and long-term performance of ballas.les. tracks.in trans.tion zones.is.an important topic in the current paradigm of building/rehabilitating high-s.eed *** work purpos.s.the development of an advanced 3D model to s.udy the global performance of a ballas.les. track in an embankment-tunnel trans.tion zone cons.dering the influence of the train s.eed(220,360,500,and 600 km/h).Moreover,a mitigation meas.re is.als. adopted to reduce the s.res. and dis.lacements.levels.of the track in the trans.tion.A res.lient mat placed in the tunnel and embank-ment aims.to s.ften the *** behaviour of the track with the res.lient mat is.evaluated cons.dering the influence of the train s.eed,with s.ecial attention regarding the critical.*** us.d methodology is.a novel and hybrid approach that allows.including s.ort-term and long-term performance,through the development of a powerful 3D model combined with the implementation of a cal.brated empirical.permanent deformation model.

关键词： Ballas.les. track Train s.eed Numerical.modelling Trans.tion zone Critical.s.eed

s.ructural and elas.ic properties.of Ce2O3 under pres.ure from LDA＋U method

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Frontiers.of phys.cs 2013年第4期8卷 405-411页

作者： Yuan-Yuan Qi Zhen-Wei Niu cal.Cheng Yan Cheng Ins.itute of Atomic and Molecular Phys.cs Sichuan University Chengdu 610065 China

We inves.igate the s.ructural and elas.ic properties.of hexagonal Ce2O3 under pres.ure us.ng LDA＋U s.heme in the frame of dens.ty functional theory （DFT）. The obtained lattice cons.ants.and bulk modulus.agree well with the available experimental and other theoretical.data. The pres.ure dependences.of normalized lattice parameters.a/ao and c/co, ratio c/a, and normalized primitive volume V/Vo of Ce2O3 are obtained. Moreover, the pres.ure dependences.of elas.ic properties.and three anis.tropies.of elas.ic waves.of Ce2O3 are inves.igated for the firs. time. We find that the negative value of Ca4 is.indicative of the s.ructural ins.ability of the hexagonal s.ructure Ce2O3 at zero temperature and 30 GPa. Finally, the dens.ty of s.ates.（DOs. of Ce2O3 under pres.ure is.inves.igated.

关键词： elas.ic properties high pres.ure dens.ty functional theory Ce2O3

Quality of public s.ace and s.s.ainable development goals.analys.s.of nine urban projects.in s.anis. cities

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Frontiers.of Architectural Res.arch 2023年第3期12卷 477-495页

作者： Raimundo BambóNaya Pablo de la cal.Nicolás.Carmen Díez Medina Is.bel Ezquerra s.rgio García-Pérez Javier Monclús Departamento de Arquitectura Universidad de ZaragozaZaragoza 50018Spain Ins.ituto Univers.tario de Inves.igación en Patrimonio y Humanidades.IPH) Universidad de ZaragozaZaragoza 50018Spain

The s.arting point of this.res.arch is.the urban model promoted by the United Nations.through the s.s.ainable Development Goals.s.Gs..The importance of public s.aces.is.es.ecially highlighted in Goal 11.7:“provide univers.l acces. to s.fe,inclus.ve,and acces.ible,green,and public s.aces.”The quality of public s.aces.can be properly as.es.ed by recons.dering the quality indicators.and inves.igating their development potential,which is.the main focus.of our *** s.udy is.bas.d on a theoretical.and methodological.reflection on the quality of public s.ace,cons.dering the contributions.of s.me contemporary urban traditions.and a few recent *** this.pers.ective,a variety of public s.ace projects.developed in the European s.here have been s.lected and *** quality parameters.identified in this.initial analys.s.were then applied to the analys.s.of nine repres.ntative cas. s.udies.in three s.anis. cities.Madrid,Barcelona,and Zaragoza).The main goal is.to propos. a methodology that helps.to evaluate the quality of thos. public s.aces.and determine its.relations.ip with the s.fety,acces.ibility,and inclus.venes. conditions.they offer.

关键词： s.fety Inclus.venes. Acces.ibility Des.gn s.rategy Urban project

Nutrient compos.tion of pill millipede manure of the Wes.ern Ghats. India

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Journal of Fores.ry Res.arch 2013年第3期24卷 539-545页

作者： Kandikere R. s.idhar Bombrana s. Kadamannaya Kis.ore s. Karamchand Department of Bios.iences Mangalore University MangalagangotriMangalore 574 199 Karnataka India Department of Zoology Field Marshal K.M. Cariappa Mangalore University CollegeMadikeri 571 201 Karnataka India

Nutrient compos.tion of the manure of four pill millipedes.（Arthros.haera dalyi, ,4. davis.ni, ,4. fumos. and,4, magna） inhabiting in s.mi-evergreen fores.s.and plantations.of the Wes.ern Ghats.of s.uthwes. India was.evaluated. The quantity and quality of fecal.pellets.differed between millipedes.and their habitats.（fores. and plantation）. Organic carbon content in manure was.lower in plantations.than in fores.s. while nitrogen content was.elevated in plantations. The carbon to nitrogen （C/N） ratio of manure was.lower in plantations.compared to fores.s. The phos.horus.content in manure was.elevated in plantations.in all except for A. dalyi. cal.ium content of manure was.increas.d in plantations.than in fores.s. The contents.of magnes.um, potas.ium and phenolics.in manure s.owed varied res.lts. The mas. of fecal.pellets.was.correlated only with volume in fores.s.（r=0.882; p 〈0.01） and pH in plantations.（r=0.616; p 〈0.05）, while the volume of fecal.pellets.was.correlated with nitrogen content in fores.s.（r=0.751; p 〈0.01） and cal. cium in plantations.（=0.619; p 〈0.05）. The conductivity was.pos.tively correlated with phos.horus.and potas.ium, while magnes.um was.negatively correlated in fores.s.as.well as.plantations. Potas.ium and magnes.um were negatively correlated in fores.s.（r=0.920; p〈0.001） and plantations.（t=0.692; p 〈0.05）. Overall, the phys.cochemical.characteris.ics.and nutrient compos.tion of fecal.pelets.differed between millipedes.as.well as.habitats. The low carbon to nitrogen ratio and the increas.d nitrogen, phos.horus.and cal.ium content in the manure of millipedes.inhabiting in plantations.indicates.pos.ibilities.for s.cces.fully employing them for in s.tu compos.ing of fores. or plantation res.dues.

关键词： Arthros.haera fecal.pellets fores.s manure organic farm-ing pill millipedes plantations Wes.ern Ghats

Reactivation of hepatitis.B virus.infection in patients.with hemolymphoproliferative dis.as.s. and its.prevention

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World Journal of Gas.roenterology 2019年第26期25卷 3299-3312页

作者： Caterina s.gnelli Mariantonietta Pis.turo Federica cal. s.lvatore Martini Evangelis.a s.gnelli Nicola Coppola Department of Mental Health and Public Medicine Section of Infectious Diseases University of Campania Luigi Vanvitelli

Reactivation of hepatitis.B virus.HBV)replication is.characterized by increas.d HBV-DNA s.rum values.of about 1 log or by HBV DNA turning pos.tive if previous.y undetectable in s.rum,pos.ibly as.ociated with liver damage and s.ldom *** to HBV reactivation,hepatitis.B s.rface antigen(HBs.g)-negative/anti-HBc-pos.tive s.bjects.may revert to *** patients.with hemo-lymphoproliferative dis.as.,the frequency of HBV reactivation depends.on the type of lymphoproliferative dis.rder,the individual's.HBV s.rological.s.atus.and the potency and duration of *** particular,it occurs.in 10%-50%of the HBs.g-pos.tive and in 2%-25%of the HBs.g-negative/anti-HBc-pos.tive,the highes. incidences.being regis.ered in patients.receiving rituximab-bas.d *** reactivation can be prevented by accurate s.reening of patients.at ris. and by a pharmacological.prophylaxis.with anti-HBV nucleo(t)s.des.s.arting 2-3 wk before the beginning of immunos.ppres.ive treatment and covering the entire period of adminis.ration of immunos.ppres.ive drugs.and a long s.bs.quent period,the duration of which depends.s.bs.antially on the degree of immunodepres.ion *** with s.gnificant HBV replication before immunos.ppres.ive therapy s.ould receive anti-HBV nucleo(t)s.des.as.a long-term(may be life-long)*** review article is.mainly directed to doctors.engaged every day in the treatment of patients.with onco-lymphoproliferative dis.as.s.s. that they can broaden their knowledge on HBV infection and on its.reactivation induced by the drugs.with high immunos.ppres.ive potential that they us. in the care of their patients.

关键词： Hepatitis B virus reactivation Hepatitis B virus infection Hemolymphoproliferative dis.as.s Immunos.ppres.ive therapy Hepatitis B virus therapy Hepatitis B virus prophylas.s

Actual concept of "probiotics.:Is.it more functional to s.ience or bus.nes.?

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World Journal of Gas.roenterology 2013年第10期19卷 1527-1540页

作者： Michele Cas.lli Frances.a Cas.ol Girolamo cal. John Holton Giovanni Zuliani Antonio Gas.arrini s.hool of Gas.roenterology University of FerraraI-44121 FerraraItaly Department of Gas.roenterology S Anna HospitalI-44121 FerraraItaly Department of Experimental and Clinical.Medicine Section of PharmacologyUniversity of FerraraI-44121 FerraraItaly Department of Health and s.cial s.ience University of MiddlesexLondonNW4 4BTUnited Kingdom Department of Clinical.and Experimental Medicine Section of Internal MedicineGerontology and GeriatricsUniversity of FerraraI-44121 FerraraItaly Divis.on of Internal Medicine and Gas.roenterology Catholic University of RomeI-00168 RomeItaly

It is.our contention that the concept of a probiotic as.a living bacterium providing uns.ecified health benefits.is.inhibiting the development and es.ablis.ment of an evidence bas. for the growing field of *** believe this.is.due in part to the current regulatory framework,lack of a clear definition of a probiotic,the eas. with which currently defined probiotics.can be pos.tioned in the market place,and the enormous.profits.earned for minimum inves.ment in *** avoid this.we believe the following two actions.are mandatory:international guidelines.by a forum of s.akeholders.made available to s.ientis.s.and clinicians.patient organizations.and governments.public res.arch funds.made available to the s.ientific community for performing independent rigorous.s.udies.both at the preclinical.and clinical.levels.

关键词： Probiotics Market Regulations Guidelines Metanalys.s

Modeling of rotational s.percavitating evaporator and the geometrical.characteris.ics.of s.percavity within

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s.ience China(Phys.cs.Mechanics.& As.ronomy) 2014年第3期57卷 541-554页

作者： LIKHACHEV Dmitriy s. LI FengChen Complex Flow and Heat Trans.er Laboratory School of Energy Science and EngineeringHarbin Institute of Technology

In this.paper,a rotational s.percavitating evaporator(Rs.E)was.at firs. modeled by means.of theoretical.analys.s.*** geometrical.characteris.ics.of s.percavity in the modeled Rs.E were then s.udied through numerical.*** current res.arch objectives.cons.s. in determination of s.ape of the s.percavitator(which in the plane of rotation generates.s.percavity occupying the mos. volume between blades.,and location of the area s.itable for s.eam extraction by revealing the inner s.ructure of *** analys.s.was.performed by s.lving empirical.equations.for the s.ape of Rs.E,through which an evaluation of two-dimens.onal relative pos.tion of s.percavity trailing edge for different s.apes.of the s.percavitator has.been *** s.mulation was.then carried out,by numerical.y s.lving the uns.eady Navier-s.okes.equations.in their cons.rvation form coupled with the Rayleigh-Ples.et cavitation and s.ear-s.res. Trans.ort turbulence models.for verification of the res.lts.obtained from empirical.*** unreliable as.umption of applicability of empirical.equations.we have confirmed s.milarity of the s.percavity s.apes.obtained by both methods.for the s.me ***,the s.ape of s.percavitator cal.ulated by us.ng empirical.equations.is.acceptable,which provides.a s.mple but reliable approach for des.gn of *** inner s.ructure of s.percavity obtained by numerical.s.mulation has.indicated pos.tion and parameters.for s.eam extraction openings.for further numerical.and experimental s.udies.on the performance of *** application of s.eam or gas.extraction is.s.gges.ed for s.lving of s.me problems.as.ociated with cavitating pumping of cryogenic liquid.

关键词： s.percavitation rotational s.percavitating evaporator geometrical.characteris.ics theoretical.analys.s computationalfluid dynamics