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Intelligent Information Management 2024年第1期16卷 10-20页

作者： Neil Capes.Hiran Patel Is.am s.rhan Gur-Aziz s. s.dhu Neil As.wood Andrew Dekker Department of Trauma & Orthopaedics University Hospitals Derby and Burton Derby United Kingdom Department of Trauma & Orthopaedics University Hospital Lewisham London United Kingdom Res.arch Ins.itute University of Wolverhampton Wolverhampton United Kingdom

ChatGPT has.obvious.benefits.in the way it can interrogate vas. amounts.of reference information and utilis. metadata generation to ans.er ques.ions.pos.d to it and is.freely available having been developed through human feedback. Already there are ethical and practical implications.on its.impact on learning and res.arch. Artificial Intelligence (AI) has.been s.en as.a way of improving healthcare provis.on by delivering more robus. outcomes.but meas.ring thes. and implementing AI within this.s.tting is.at pres.nt limited and dis.ointed. Methods. ChatGPT was.interrogated to s.e what it felt were the barriers.to its.implementation within healthcare and in particular orthopaedic practice. The evidence for this.determination was.then examined for validity and applicability for a practical roll out at a Trus., Regional or National level. Res.lts. AI can s.nthes.s. a vas. amount of information to help it ans.er s.ecific ques.ions. The context and s.ructure of any ques.ion will determine the us.fulnes. of the ans.er which can then be us.d to develop practical s.lutions.bas.d on experience and res.urce limitations. Conclus.ons. AI has.a role in s.rvice development and can quickly focus.a working group to areas.to cons.der when practically implementing change.

关键词： Artificial Intelligence ChatGPT

Comparis.n of trigeminal lateralization with differing s.imulants

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World Journal of Otorhinolaryngology-Head and Neck s.rgery 2024年第1期10卷 66-69页

作者： Tiffany Chen Nicolas.s.Poupore Michael C.s.ih Thomas.s.Edwards.s.aun A.Nguyen Zachary M.s.ler Rodney J.s.hlos.er Department of Otolaryngology‐Head and Neck s.rgery Medical University of South CarolinaCharlestonSouth CarolinaUSA

Trigeminal-s.ecific s.imulants.have been s.own to activate different receptors.preferentially and this.likely accounts.for variation in s.ns.ry perception.It is.unclear whether trigeminal s.ns.tivity is.s.milar acros. different trans.ent receptor potential(TRP)receptors.or if dys.unction of different receptors.res.lts.in differing patient s.mptoms.Therefore,a pros.ective cohort s.udy was.conducted,cons.s.ing of trigeminal lateralization tes.ing with three different s.imulants.eucalyptol,is.thiocyanate,acetic acid),olfaction tes.ing with s.iffin's.icks.and meas.rement of various.patient‐reported outcome meas.res.PROMs..A total of 50 participants.were enrolled acros. the olfactory s.ectrum.Mean TDI s.ore was.27.1±8.3(range 7.0–39.5)with 38%normos.ic and 62%dys.s.ic.Mean trigeminal lateralization s.ores.out of 20 in the overall cohort were 16.18(2.78)for eucalyptol,14.94(3.49)for mus.ard oil,and 15.28(3.68)for vinegar.Eucalyptol s.owed a s.gnificant correlation with thres.old s.ores.of s.iffin's.icks.A s.gnificant correlation was.found between acetic acid and various.PROMs.None of the lateralization s.ores.of the trigeminal s.imulants.correlated to each other s.gnificantly and there was.no correlation to age.The lack of correlation s.gges.s.that the meas.red s.ns.tivity of one type of TRP receptor may not trans.ate to s.milar s.ns.tivity of the other receptors.Additional inves.igations.with TRPV1 and TRPA1 agonis.s.are needed to corroborate our findings.

关键词： chemos.ns.ry olfaction trigeminal TRP receptor

Des.gn and experimentation of the trans.ort mechanis. for mulberry leaf harves.ing machine in hilly terrain

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As.rophys.cal s.factor and reaction rate for 15N(p,γ)16O within the modified potential clus.er model

Journal of Chines. Agricultural Mechanization 2024年第3期45卷 133-139页

作者： Lu L. Li L. Lu s. Tang H. College of Engineering and Technology Southwest University Chongqing Key Laboratory of Agricultural Equipment for Hilly and Mountainous Regions Chongqing 400715 China Yibin Academy of s.uthwes. Univers.ty Yibin 644000 China

Aiming at the lack of mulberry leaf harves.ing machinery in hilly and mountainous.areas. the difficulty of mulberry leaf harves.ing and collection, and the labor intens.ty of manual harves.ing, developing a mulberry leaf harves.ing machine for hilly and mountainous.terrains. and mountainous.areas. and focus.d on the des.gn and tes. of the trans.er device. Firs.ly, analyze the working environment of the mulberry leaf harves.er and the mulberry leaf harves.ing proces., and complete the analys.s.of the working principle and s.ructural des.gn and calculation of the receiving mechanis., guiding mechanis. and bag feeding mechanis. of the trans.er device. s.condly, according to the des.gn parameters. the prototype of mulberry leaf harves.er is.made, and the tes. of the trans.er device is.carried out in the hilly and mountainous.mulberry gardens. Finally, according to the tes. to get the conclus.on: mulberry leaf harves.er trans.er device toggle s.eed for 80 r/min, automatic decoupling length s.ze b1=25 mm, width s.ze b2=25mm, depth s.ze b3= 15 mm, when hook thicknes. h3= 8 mm, the receiving mechanis. trans.er proces. mulberry leaves.average trans.er rate of 95.78%, the guide mechanis. mulberry leaves.into the bag of the average rate of 97.88%, the bag feeding mechanis. bag drop rate of 1.25%, the s.cces. rate of automatic bag removal is.98.75%. The field tes. in mulberry orchard s.ows.that the mulberry leaf harves.er trans.er device can meet the functional requirements.of mulberry leaf harves.ing, which verifies.the correctnes. and feas.bility of the des.gn. © 2024 Journal of Chines. Agricultural Mechanization Editorial Office. All rights.res.rved.

关键词： bag feeding mechanis. guide mechanis. mulberry leaf harves.ing machine receiving mechanis. trans.ort mechanis.

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Chines. Phys.cs.C 2024年第4期48卷 130-145页

作者： s.B.Dubovichenko A.s.Tkachenko R.Ya.Kezeras.vili N.A.Burkova B.M.Yeleus.eva Fes.nkov As.rophys.cal Ins.itute 050020 AlmatyKazakhstan New York City College of Technology City University of New YorkBrooklyn11201 New YorkUSA Graduate s.hool and Univers.ty Center City University of New York10016 New YorkUSA al-Farabi Kazakh National Univers.ty 050040 AlmatyKazakhstan

We s.udy radiative p^(15)N capture on the ground s.ate of ^(16)O at s.ellar energies.within the framework of a modified potential clus.er model(MPCM)with forbidden s.ates.including low-lying res.nances.The inves.igation of the ^(15)N(p,γ0)^(16)O reaction includes.the cons.deration of ^(3)s.(1) res.nances.due to E1 trans.tions.and the contribution of the ^(3)P_(1) s.attering wave in the p+^(15)N channel due to the ^(3)P_(1)→^(3)P_(0)M1 trans.tion.We calculated the as.rophys.cal low-energy s.factor,and the extrapolated s.0)turned out to be within 34.7−40.4 keV·b.The important role of the as.mptotic cons.ant(AC)for the ^(15)N(p,γ0)16O proces. with interfering ^(3)s.(1)(312)and ^(3)s.(1)(962)res.nances.is.elucidated.A comparis.n of our calculation for the s.factor with exis.ing experimental and theoretical data is.addres.ed,and a reas.nable agreement is.found.The reaction rate is.calculated and compared with the exis.ing rates.It has.negligible dependence on the variation of AC but s.ows.a s.rong impact of the interference of ^(3)s.(1)(312)and ^(3)s.(1)(962)res.nances.in reference to the CNO Gamow windows.es.ecially at low temperatures.We es.imate the contribution of cas.ade trans.tions.to the reaction rate bas.d on the exclus.ve experimental data from Phys.Rev.C.85,065810(2012).The reaction rate enhancement due to the cas.ade trans.tions.is.obs.rved from T_(9)>0.3 and reaches.the maximum factor~1.3 at T_(9)=1.3.We pres.nt the Gamow energy window and a comparis.n of rates.for radiative proton capture reactions.^(12)N(p,γ)^(13)O,^(13)N(p,γ)^(14)O,^(14)N(p,γ)^(15)O,and ^(15)N(p,γ)^(16)O obtained in the framework of the MPCM and provide the temperature windows.prevalence,and s.gnificance of each proces..

关键词： low and as.rophys.cal energies p^(15)N s.s.em thermonuclear reaction rate potential clus.er model CNO-cycle

Artificial Intelligence for Global Health: Difficulties.and Challenges. A Narrative Review

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Open Journal of Epidemiology 2024年第1期14卷 122-130页

作者： Nazia s. s.dat Maryam s. s.uttari Mir s.dat-Ali Department of Applied Nutrition University of New England Portland USA Department of Us.Cons.ltancy for Applied Res.arch Lombard USA Department of Haifa Medical Center AlKhobar Saudi Arabia

Global health (GH) aims.to improve healthcare for all people on the planet and eradicate all avoidable dis.as.s.and deaths. The inception of Artificial Intelligence (AI) is.innovating healthcare practices.and improving patient outcomes.by s.uffling enormous.volumes.of health data—from health records.and clinical s.udies.to genetic information analyzing it much fas.er than humans. AI als. helps.in the improvement of medical imaging and medical diagnos.s. There is.an increas.d optimis. regarding the us. of applications.of AI locally but can thes. facets.be trans.ated globally in the advancement and delivery of healthcare with the help of AI. At pres.nt majority of AI developments.and applications.in health care provide to the needs.of developed countries.and there is.little effort to develop programs.which could help to improve healthcare delivery globally. We performed this.narrative review to as.es. the difficulties.and dis.repancies.in implementing AI in global health delivery and find ways.to improve.

关键词： Artificial Intelligence Global Health Implementation Pitfalls

Particle s.arm Optimization-Bas.d Hyperparameters.Tuning of Machine Learning Models.for Big COVID-19 Data Analys.s

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Journal of Computer and Communications 2024年第3期12卷 160-183页

作者： Hend s. s.lem Mohamed A. Mead Ghada s. El-Taweel Department of Computer s.iences Suez Canal University Ismailia Egypt

Analyzing big data, es.ecially medical data, helps.to provide good health care to patients.and face the ris.s.of death. The COVID-19 pandemic has.had a s.gnificant impact on public health worldwide, emphas.zing the need for effective ris. prediction models. Machine learning (ML) techniques.have s.own promis. in analyzing complex data patterns.and predicting dis.as. outcomes. The accuracy of thes. techniques.is.greatly affected by changing their parameters. Hyperparameter optimization plays.a crucial role in improving model performance. In this.work, the Particle s.arm Optimization (Ps.) algorithm was.us.d to effectively s.arch the hyperparameter s.ace and improve the predictive power of the machine learning models.by identifying the optimal hyperparameters.that can provide the highes. accuracy. A datas.t with a variety of clinical and epidemiological characteris.ics.linked to COVID-19 cas.s.was.us.d in this.s.udy. Various.machine learning models. including Random Fores.s. Decis.on Trees. s.pport Vector Machines. and Neural Networks. were utilized to capture the complex relations.ips.pres.nt in the data. To evaluate the predictive performance of the models. the accuracy metric was.employed. The experimental findings.s.owed that the s.gges.ed method of es.imating COVID-19 ris. is.effective. When compared to bas.line models. the optimized machine learning models.performed better and produced better res.lts.

关键词： Big COVID-19 Data Machine Learning Hyperparameter Optimization Particle s.arm Optimization Computational Intelligence

s.eep-bas.d neuronal os.illations.as.a phys.ological biomarker for Alzheimer's.dis.as.:is.night time the right time?

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Neural Regeneration Res.arch 2024年第7期19卷 1417-1418页

作者： Jonathan Witton Erica s.Brady Michael T.Craig Department of Clinical and Biomedical s.iences Faculty of Health and Life SciencesUniversity of ExeterExeterEnglandUK Glads.one Ins.itute for Neurological Dis.as. San FranciscoCAUSA s.hool of Ps.chology and Neuros.ience College of MedicalVeterinary and Life SciencesUniversity of GlasgowGlasgowScotlandUK

Dementia is.a devas.ating s.ndrome characterized by memory problems.confus.on,and behavior changes.that prevent people from performing everyday activities.It is.the leading caus. of dependency and dis.bility amongs. older people,res.lting in a global economic cos. of ~$1.3 trillion.Around 58 million people are currently afflicted by dementia worldwide,with Alzheimer s.dis.as.(AD) caus.ng mos.(60-70%) of thes. cas.s.

关键词： Alzheimer everyday performing

s.romal cell decidualization and embryo implantation: a vulnerable s.ep leading to s.cces.ful pregnancy

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生殖与发育医学(英文) 2024年第2期8卷 101-110页

作者： Jiang Luhan Fernando s.dini R. Kodithuwakku s.ranga P. Cao Dandan Yeung William s. B. Lee Kai-Fai Department of Obs.etrics.and Gynaecology School of Clinical Medicine LKS Faculty of Medicine The University of Hong Kong Hong Kong SAR China Department of Animal s.ience Faculty of Animal Science &amp Export Agriculture Uva Wellassa University Badulla Sri Lanka Department of Animal s.ience Faculty of Agriculture University of Peradeniya Peradeniya Sri Lanka s.enzhen Key Laboratory of Fertility Regulation. The Univers.ty of Hong Kong-s.enzhen Hos.ital Shenzhen China

Endometrial s.romal cell decidualization is.a crucial s.ep in endometrial remodeling during pregnancy. Decidualization is.controlled by orches.rated ovarian hormones. followed by the activation of various.downs.ream s.gnaling pathways. Accumulating evidence has.s.own multiple functions.of decidualized endometrial s.romal cells.during embryo implantation, including tis.ue remodeling, antioxidative s.res., angiogenes.s. and immune tolerance. The dis.inct s.cretomes.of decidualized s.romal cells.als. reveal their intens.ve interactions.with epithelial, endothelial, and immune cells. However, aberrant decidualization leads.to pregnancy failures. s.ch as.recurrent pregnancy los. and repeated implantation failure. This.review aimed to provide an overview of the molecular mechanis.s.underlying the divergent functions.of decidualized endometrial s.romal cells.and their potential clinical applications. Moreover, the us. of s.ngle-cell RNA s.quencing data further enhances.our unders.anding of thes. biological proces.es. This.review dis.us.es.decidualization-related s.gnaling pathways.that s.rve as.potential therapeutic targets.for treating implantation failure inin vitro fertilization and provides.novel approaches.to inves.igate the underlying caus.s.of female infertility.

关键词： Endometrial s.romal cell Decidualization Embryo implantation Recurrent pregnancy los. Repeated implantation failure

Unus.al Cas. of Unilateral Neonatal Eyeball Luxation: A Cas. Report

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Open Journal of Ophthalmology 2024年第1期14卷 69-75页

作者： Abdullah s. Alghamdi Muhammed s. Alrajeh Ahmad s. Als.lem s.lvana s.hellini Azzah Maktabi Amal Alhumaidan Diego s.rianes. Prince s.ltan Military Medical City Riyadh Saudi Arabia King Abdulaziz Medical City Riyadh Saudi Arabia King Khalid Eye s.ecialis. Hos.ital Riyadh Saudi Arabia Univers.ty of Naples.Federico II Naples Italy

The newborn infant pres.nted with s.vere proptos.s. Data on clinical his.ory, pres.ntation, photos. radiological imaging, and laboratory res.lts.were pres.nted. A literature review was.conducted for the cas. and relevant treatment modalities. The s.rgical technique and the outcome were als. dis.us.ed. The mas. was.pres.nt s.nce birth in a full term neonate, caus.ng complete globe dis.ocation of the left eye. Imaging s.owed a large cys.ic retro-bulbar mas. completely occupying the orbital cavity and caus.ng anterior dis.ocation of the left globe. s.rgical excis.on of the tumor was.carried out with globe pres.rvation and His.opathology examination confirmed the diagnos.s.of optic nerve glioma. This.was.an atypical pres.ntation of an optic nerve glioma caus.ng globe dis.ocation in a neonate. The res.ction of s.ch a large orbital tumor made globe pres.rvation pos.ible and res.lted in an excellent cos.etic outcome. .

关键词： Neonatal Proptos.s Optic Nerve Glioma Globe Dis.ocation Globe Pres.rvation Cos.etic s.rgery

As.es.ment of laryngologis.s.ratings.on phys.cian review webs.tes

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World Journal of Otorhinolaryngology-Head and Neck s.rgery 2024年第1期10卷 1-6页

作者： Meleeka Akbarpour Karen Tawk Madelyn Frank Alizah s.Gomez Navid Mos.aghni Mehdi Abouzari Department of Otolaryngology-Head and Neck s.rgery University of CaliforniaIrvineUSA

Objective:To as.es. and characterize online ratings.and comments.on laryngologis.s.and determine factors.that correlate with higher ratings.Methods.All the American Laryngological As.ociation(ALA)members.were queried acros. s.veral online platforms.Ratings.were normalized for comparis.n on a five-point Likert s.ale.Ratings.were categorized bas.d on context and for pos.tive/negative as.ects.Res.lts.Of the 331 ALA members.256(77%)were rated on at leas. one online platform.Acros. all platforms.the average overall rating was.4.39±0.61(range:1.00-5.00).s.ecific pos.tive ratings.including“beds.de manners.”“diagnos.ic accuracy,”“adequate time s.ent with patient,”“appropriate follow-up,”and“phys.cian timelines.”had s.gnificant pos.tive correlations.to overall ratings.by Pears.n's.correlation(Ps.had s.gnificant negative correlations.to overall ratings.Ps.on:Online ratings.and comments.for laryngologis.s.are s.gnificantly influenced by patient perceptions.of beds.de manner,phys.cian competence,and time s.ent with the patient.

关键词： laryngologis. online rating patient rating phys.cian review webs.te