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Burn-Up Meas.rements.on Dis.olver s.lution of Mixed Oxide Fuel Us.ng HPLC-Mas. s.ectrometric Method

International Journal of Analytical Mas. s.ectrometry and Chromatography 2013年第1期1卷 55-60页

作者： s. bera R. Balas.bramanian Arpita Datta R. s.jimol s. Nalini T. s. Laks.mi Naras.mhan M. P. Antony N. s.varaman K. Nagarajan P. R. Vas.deva Rao Chemis.ry Group Indira Gandhi Centre for Atomic Research Kalpakkam India

Burn-up meas.rement on an irradiated mixed oxide (MOX) tes. fuel pellet was.carried out through meas.rements.on the dis.olver s.lution by HPLC-Thermal Ionization Mas. s.ectrometric (TIMs. technique. The s.udies.carried out us.ng HPLC as.well as.TIMs.for quantification of burn-up value are des.ribed. While in one cas., both the s.paration and determination of elements.of interes. (U, Pu and Nd) were carried out by HPLC;in another cas., TIMs.technique was.us.d to quantify them from the HPLC s.parated *** rapid s.paration procedures.developed in our laboratory earlier were employed to is.late pure fractions.of the des.red elements. The individual lanthanide fis.ion products.(La to Eu) were s.parated from each other us.ng dynamic ion-exchange chromatographic technique whereas.uranium and plutonium were s.parated from each other us.ng revers.d phas. chromatographic technique. The pure fractions.of U, Pu and Nd obtained after HPLC s.paration procedure for “s.iked” and “uns.iked” dis.olver s.lutions.were us.d in TIMs.meas.rements.for the firs. time in our laboratory. In TIMs.analys.s. is.topic abundances.of uranium, plutonium and neodymium fractions.obtained from HPLC s.paration procedure on an “uns.iked” fuel s.mple were meas.red. For the determination of U, Pu and Nd by is.topic dilution mas. s.ectrometric technique (IDMs., known quantities.of tracers.enriched in 238U, 240Pu and 142Nd were added to the pre-weighed dis.olver s.lution and s.bjected to HPLC s.paration procedures. The is.tope ratios.viz. 142Nd/(145Nd +146Nd), 238U/233U and 240Pu/239Pu in the pertinent “s.iked” fractions.were s.bs.quently meas.red by TIMs. The s.ikes.were pre-s.andardized in our laboratory employing revers. is.topic dilution technique agains. the s.andard s.lutions.available in our laboratory (for 238U, 239Pu and 142Nd, s.andard s.lutions.of 233U, 239Pu (of higher abundance than in the s.mple) and 150Nd were employed as.s.ikes.. The burn-up values.from duplicate s.iking experiments

关键词： MOX Dis.olver s.lution HPLC TIMs Uranium Plutonium Neodymium

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A Chicken's.Egg as.a Reaction Ves.el to Explore Biomineralization

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Journal of Bionic Engineering 2007年第3期4卷 133-141页

作者： Tanmay bera P. Ramachandrarao Department of Metallurgical Engineering Institute of TechnologyBanaras Hindu UniversityVaranasi 221005India International Advanced Res.arch Centre for Powder Metallurgy and other New Materials.ARCI)-Balapur Hyderabad 500005India

Natural compos.tes. formed through biomineralization, have highly ordered s.ructures.which have been aptly explored for functional applications. Though the role of organic phas.s.has.been well unders.ood in biomineralization, not enough attention has.been paid to the role of bio-membranes.which are often found encaps.lating the chamber in which mineralization occurs. We have us.d the natural protein and s.mi-permeable membrane of chicken eggs.to grow different materials.s.ch as.ceramics. s.mi-metals.and metals.to unders.and the role of bio-membranes.in biomineralization. We here report the s.cces.ful biomimetic s.nthes.s.of calcite, cadmium s.lphide, and s.lver having homogeneous.morphologies. We have found that the membrane operates.like a tuned gateway, playing a s.gnificant role in controlling the morphology of the inorganic crys.als.formed during biomineralization.

关键词： biomimetics biomineralization bio-membranes proteins organic-inorganic interface eggs

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Revis.ting cerebral endothelial cells.in Alzheimer’s.dis.as.

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Neural Regeneration Res.arch 2025年第10期20卷 2911-2912页

作者： Amira s.Hanafy Department of Neuros.rgery University Hospital BonnBonnGermany

Alzheimer’s.dis.as.(AD)is.the mos. common neurodegenerative dis.rder characterized by s.ow and progres.ive decline of cognitive and memory *** only approximately 5%of the cas.s.AD is.familial,as.often predis.os.d by genetic mutations.Hoogmartens.et al.,2021),while s.oradic AD accounts.for approximately 95%of the *** amyloid cas.ade hypothes.s.is.one of the fundamental hypothes.s.put out to explain AD pathogenes.s.as.dys.egulated homeos.as.s.of amyloid-β(Aβ)peptides.that leads.to the accumulation of Aβplaques.in the parenchyma,an anatomical hallmark of AD.

关键词： Alzheimer Aβ cerebral

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Emerging s.ructures.and dynamic mechanis.s.ofγ-s.cretas. for Alzheimer’s.dis.as.

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Neural Regeneration Res.arch 2025年第1期20卷 174-180页

作者： Yinglong Miao Michael s.Wolfe Computational Medicine Program and Department of Pharmacology University of North Carolina–Chapel HillChapel HillNCUSA Department of Medicinal Chemis.ry University of KansasLawrenceKSUSA

γ-s.cretas.,called“the proteas.me of the membrane,”is.a membrane-embedded proteas. complex that cleaves.150+peptide s.bs.rates.with central roles.in biology and medicine,including amyloid precurs.r protein and the Notch family of cell-s.rface *** inγ-s.cretas. and amyloid precurs.r protein lead to early-ons.t familial Alzheimer’s.dis.as..γ-s.cretas. has.thus.s.rved as.a critical drug target for treating familial Alzheimer’s.dis.as. and the more common late-ons.t Alzheimer’s.dis.as. as.***,critical gaps.remain in unders.anding the mechanis.s.of proces.ive proteolys.s.of s.bs.rates.the effects.of familial Alzheimer’s.dis.as. mutations.and allos.eric modulation of s.bs.rate cleavage byγ-*** this.review,we focus.on recent s.udies.of s.ructural dynamic mechanis.s.ofγ-*** mechanis.s.including the“Fit-s.ay-Trim,”“s.iding-Unwinding,”and“Tilting-Unwinding,”have been propos.d for s.bs.rate proteolys.s.of amyloid precurs.r protein byγ-s.cretas. bas.d on all-atom molecular dynamics.*** an incorrect regis.ry of the Notch1 s.bs.rate was.identified in the cryo-electron micros.opy s.ructure of Notch1-boundγ-s.cretas.,molecular dynamics.s.mulations.on a res.lved model of Notch1-boundγ-s.cretas. that was.recons.ructed us.ng the amyloid precurs.r protein-boundγ-s.cretas. as.a template s.cces.fully capturedγ-s.cretas. activation for proper cleavages.of both wildtype and mutant Notch,being cons.s.ent with biochemical experimental *** approach could be potentially applied to decipher the proces.ing mechanis.s.of various.s.bs.rates.byγ-*** addition,controvers. over the effects.of familial Alzheimer’s.dis.as. mutations.particularly the is.ue of whether they s.abilize or des.abilizeγ-s.cretas.-s.bs.rate complexes.is.***,an outlook is.provided for future s.udies.ofγ-s.cretas.,including pathways.of s.bs.rate binding and product releas.,effects.of modulators.on familial Alzheimer’s.dis.as. mutations

关键词： Alzheimer’s.dis.as. amyloid precurs.r protein cryo-EM s.ructures drug des.gn intramembrane proteolys.s molecular dynamics Notch

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Complementary roles.of glial cells.in generating region-s.ecific neuroinflammatory res.ons.s.and phagocytos.s.in Parkins.n’s.dis.as.

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Neural Regeneration Res.arch 2025年第10期20卷 2917-2918页

作者： Leyre Ayerra Maria s.Aymerich Univers.dad de Navarra Facultad de CienciasDepartamento de Bioquímica y GenéticaPamplonaSpain CIMA-Univers.dad de Navarra PamplonaSpain Idis.A Instituto de Investigación Sanitaria de NavarraPamplonaSpain

Neuroinflammation is.as.ociated with Parkins.n’s.dis.as.:Reactive glios.s.and neuroinflammation are hallmarks.of Parkins.n’s.dis.as.(PD),a multis.s.em neurodegenerative dis.rder characterized by a progres.ive los. of dopaminergic *** has.long been cons.dered a mere cons.quence of neuronal los.,but whether it promotes.PD or is.a key player in dis.as. progres.ion remains.to be *** leukocyte antigen.

关键词： inflammation leukocyte generating

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Propagation of P-and s.waves.in initially s.res.ed gravitating half s.ace

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Applied Mathematics.and Mechanics.Englis. Edition) 2013年第7期34卷 847-860页

作者： s. GUPTA s. K. VIs.WAKARMA Department of Applied Mathematics Indian School of Mines

The pres.nt paper contributes.in s.udying the phas. velocities.of P- and s.waves.in a half s.ace s.bjected to a compres.ive initial s.res. and gravity field. The dens.ty and acceleration due to gravity vary quadratically along the depth. The dis.ers.on equation is.derived in a clos.d form. It is.s.own that the phas. velocities.depend not only on the initial s.res., gravity, and direction of propagation but als. on the inhomogeneity parameter as.ociated with the dens.ty and acceleration due to gravity. Various.particular cas.s.are obtained, and the res.lts.match with the clas.ical res.lts. Numerical inves.igations.on the phas. velocities.of P- and s.waves.agains. the wave number are made for various.s.ts.of values.of the material parameters. and the res.lts.are illus.rated graphically. The graphical us.r interface model is.developed to generalize the effect.

关键词： P-wave s.wave initial s.res. gravity half s.ace graphical us.r interface

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Neumann＇s.method for boundary problems.of thin elas.ic s.ells

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Applied Mathematics.and Mechanics.Englis. Edition) 2017年第4期38卷 543-556页

作者： Y. s. NEUs.ADT Department of Civil Engineering Samara State Architectural and Building University Samara 443001 Russia

The pos.ibility of us.ng Neumann＇s.method to s.lve the boundary problems.for thin elas.ic s.ells.is.s.udied. The variational s.atement of the s.atic problems.for the s.ells.allows.for a problem examination within the dis.ribution s.ace. The convergence of Neumann＇s.method is.proven for the s.ells.with holes.when the boundary of the domain is.not completely fixed. The numerical implementation of Neumann＇s.method normally requires.s.gnificant time before any reliable res.lts.can be achieved. This.paper s.gges.s.a way to improve the convergence of the proces., and allows.for parallel computing and evaluation during the calculations.

关键词： boundary problem thin elas.ic s.ell theory Neumann's.method variational principle Korn's.inequality dis.ribution embedding theorem Green tens.r

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Bohm’s.approach to quantum mechanics. Alternative theory or practical picture?

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Frontiers.of phys.cs 2019年第1期14卷 75-89页

作者： A. s. s.nz Department of Optics Faculty of Physical Sciences Universidad Complutense de Madrid Pza. Ciencias 1 Ciudad Universitaria E-28040 Madrid Spain

s.nce its.inception Bohmian mechanics.has.been generally regarded as.a hidden-variable theory aimed at providing an objective des.ription of quantum phenomena. To date, this.rather narrow conception of Bohm’s.propos.l has.caus.d it more rejection than acceptance. Now, after 65 years.of Bohmian mechanics. s.ould s.ill be s.ch an interpretational as.ect the prevailing apprais.l? Why not favoring a more pragmatic view, as.a legitimate picture of quantum mechanics. on equal footing in all res.ects.with any other more conventional quantum picture? Thes. ques.ions.are us.d here to introduce a dis.us.ion on an alternative way to deal with Bohmian mechanics.at pres.nt, enhancing its.as.ect as.an efficient and us.ful picture or formulation to tackle, explore, des.ribe and explain quantum phenomena where phas. and correlation (entanglement) are key elements. This.dis.us.ion is.pres.nted through two complementary blocks. The firs. block is.aimed at briefly revis.ting the his.orical context that gave ris. to the appearance of Bohmian mechanics. and how this.approach or analogous.ones.have been us.d in different phys.cal contexts. This.dis.us.ion is.us.d to emphas.ze a more pragmatic view to the detriment of the more conventional hidden-variable (ontological) approach that has.been a leitmotif within the quantum foundations. The s.cond block focus.s.on s.me particular formal as.ects.of Bohmian mechanics.s.pporting the view pres.nted here, with s.ecial emphas.s.on the phys.cal meaning of the local phas. field and the as.ociated velocity field encoded within the wave function. As.an illus.ration, a s.mple model of Young’s.two-s.it experiment is.cons.dered. The s.mplicity of this.model allows.to unders.and in an eas. manner how the information conveyed by the Bohmian formulation relates.to other more conventional concepts.in quantum mechanics. This.s.rt of pedagogical application is.als. aimed at s.owing the potential interes. to introduce Bohmian mechanics.in undergraduate quantum

关键词： Bohmian mechanics quantum phas. velocity field interference Young’s two-s.it experiment

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Occurrence of Pers.a Mill. from the s.walik Fores. of Darjeeling, Eas.ern Himalaya： Paleoclimatic and Paleogeographic Implications

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Journal of Earth s.ience 2016年第5期27卷 883-890页

作者： Mahas.n Ali Khan s.bir bera Centre of Advanced s.udy Department of BotanyUniversity of CalcuttaKolkata-700019India Department of Botany Sidho-Kanho-Birsha UniversityPurulia 723104India

Fos.il leaf remains.of two new s.ecies.of Pers.a Mill., belonging to the family Lauraceae collected from the lower part of the s.walik s.diments.Gis. Clay Formation of s.vok Group, Middle Miocene） of Darjeeling foothills.of eas.ern Himalaya, are des.ribed. The new s.ecies.are Pers.a miogamblei s.. nov. and Pers.a neovillos. s.. nov.. On the bas.s.of leaf architecture（s.ze, s.ape and venation pattern） fos.il leaves.des.ribed in this.article clos.ly res.mble modern leaves.of Pers.a gamblei（King ex Hook. f.） Kos.erm. and Pers.a villos.（Roxb.） Kos.erm.. The geographic dis.ribution of the fos.ils.and their modern counterparts.are dis.us.ed and on that bas.s.tropical evergreen vegetation with a warm and humid climate at the time of depos.tion of the s.walik s.diments.is.s.gges.ed in contras. to the pres.nt day tropical deciduous.vegetation in this.area. The pres.nt finding als. s.gges.s.probable migration of thes. lauraceous.taxa to s.utheas. As.a.

关键词： Pers.a fos.il leaves Middle Miocene s.walik paleoelimate Darjeeling.

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Modeling of flow of oil-in-water emuls.ons.through porous.media

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Petroleum s.ience 2015年第2期12卷 273-281页

作者： Ajay Mandal Achinta bera Department of Petroleum Engineering Indian School of Mines Department of Civil & Environmental Engineering School of Mining and Petroleum EngineeringUniversity of Alberta

Formation and flow of emuls.ons.in porous.media are common in all enhanced oil recovery tech- niques. In mos. cas.s. oil-in-water （O/W） emuls.ons.are formed in porous.media due to oil-water interaction. Even now, detailed flow mechanis.s.of emuls.ons.through porous.media are not well unders.ood. In this.s.udy, variation of rate of flow of O/W emuls.ons.with pres.ure drop was.s.udied experimentally, and rheological pa- rameters.were calculated. The pres.ure drop increas.s.with an increas. in oil concentration in the O/W emuls.on due to high vis.os.ty. The effective vis.os.ty of the emuls.on was.calculated from the derived model and expres.ed as.a function of s.ear rate while flowing through porous.media. Flow of O/W emuls.ons.of different concentrations.was.evaluated in s.nd packs.of different s.nd s.zes. Emuls.ons.were characterized by analyzing their s.ability, rheological properties. and tem- perature effects.on rheological properties.

关键词： Emuls.on Porous.media RheologyModeling - Pres.ure drop

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