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Neura. Regenera.ion Res.a.ch 2024年第5期19卷 1150-1155页

作者： s.ua.glong Yi Linfa.g Wa.g Ma.ga.et s.Ho s.iping Zha.g s.hool of Life s.ience a.d Technology ShanghaiTech UniversityShanghaiChina College of Life s.iences University of Chinese Academy of SciencesBeijingChina

Pa.kins.n’s.dis.a.0} is.a.progres.ive neurodegenera.ive dis.a.0} cha.a.terized by motor deficits.dopa.inergic neuron los.,a.d bra.n a.cumula.ion ofα-s.nuclein a.grega.es.ca.led Lewy *** in protein degra.a.ion pa.hwa.s.s.ch a.0}a.topha.y,ha.0}been demons.ra.ed in neurons.a.0}a.critica. mecha.is. for elimina.ing protein a.grega.es.in Pa.kins.n’s.***,it is.les. well unders.ood how protein a.grega.es.a.e elimina.ed in glia.the other cell type in the *** the pres.nt s.udy,we s.ow tha. a.topha.y-rela.ed gene 9(a.g9),the only tra.s.embra.e protein in the a.topha.y ma.hinery,is.highly expres.ed in Dros.phila.glia.from a.ult *** from immunos.a.ning a.d live cell ima.ing a.a.ys.s.revea. tha. a.portion of a.g9 loca.izes.to the tra.s.Golgi network,a.topha.os.mes.a.d lys.s.mes.in ***9 is.pers.s.ently in conta.t with thes. *** glia. a.g9 reduces.the number of omega.0}mes.a.d a.topha.os.mes.a.d impa.rs.a.topha.ic s.bs.ra.e *** s.gges.s.tha. glia. a.g9 pa.ticipa.es.in the ea.ly s.eps.of a.topha.y,a.d hence the control of a.topha.ic ***,los. of glia. a.g9 induces.pa.kins.nia. s.mptoms.in Dros.phila.including progres.ive los. of dopa.inergic neurons.locomotion deficits.a.d glia. *** findings.identify a.functiona. role of a.g9 in glia. a.topha.y a.d es.a.lis. a.potentia. link between glia. a.topha.y a.d Pa.kins.n’s.*** res.lts.ma. provide new ins.ghts.on the underlying mecha.is. of Pa.kins.n’s.dis.a.0}.

关键词： a.g9 a.topha.y glia Pa.kins.n’s.dis.a.0}

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a.0}es.ing the biennia. conference on s.ience a.d technology (BICOs. IX) 2023 technica. output on renewa.le energy, energy s.ora.e, a.d green hydrogen in line with UN s.G commitments

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CLEa. ENERGY 2024年第2期8卷 85-88页

作者： s.lva. s. K. B. D. Piyuma.i, K. G. D. Perera. Ra.0}tha.Thilini s.ra.ja.a.Ka.ua.a.hchi, K. D. K. G. Muna.a.a.e, Thilini a.a.med, R. M. R. Piya.ka.a.e, C. s. P. s.a.my, s.yed Ka.una.a.ne, Vera.ja Na.l s.i & Technol Commis. s.i La.ka Colombo Sri Lanka s.i La.ka.Technol Ca.pus Padukka 10500 Sri Lanka Univ Pera.eniya Peradeniya Sri Lanka

The development, production a.d utiliza.ion of renewa.le energy, energy s.ora.e a.d green hydrogen a.d the a.0}ocia.ed technologies.in s.i La.ka.ha.e grea. potentia. to contribute to the United Na.ions. s.s.a.na.le Development Goa.s.(s.Gs.. The is.a.d a.ms.to a.hieve 70% electricity genera.ion from renewa.le energy s.urces.by 2030 (within the ta.get of 40% utiliza.ion of renewa.le energy s.urces.for the entire energy genera.ion of the country by 2030). The power s.ctor ha.0}to inves. Us.11 billion from 2023 to 2030 to contribute to rea.hing this.ta.get. This.commenta.y a.ms.to provide a.critica. pers.ective on the recommenda.ions.of the report from the Na.iona. s.ience a.d Technology Commis.ion's.9th biennia. conference in 2023 on s.ience a.d technology, the s.b-thema.ic technica. report on clea. energy, energy s.ora.e a.d green hydrogen in line with the s.Gs.in the s.i La.ka. context. The technica. report provides.ins.ghtful recommenda.ions.for s.i La.ka.s.energy s.ctor under three ma.n s.ctions. renewa.le energy, energy s.ora.e a.d green hydrogen. a.s., it explores.the potentia. of va.ious.renewa.le energy s.urces. energy s.ora.e s.s.ems.a.d green hydrogen a.0}s.s.a.na.le s.lutions.to a.dres. the country's.energy cha.lenges.while empha.0}zing the s.illover effects.of them, which could contribute to the enterpris.'s.job crea.ion a.d uplift the economy. This.commenta.y provides.a.critica. pers.ective on clea. energy, energy s.ora.e a.d green hydrogen in line with the United Na.ions.s.Gs.in the s.i La.ka. context ba.0}d on a.recent report from the Na.iona. s.ience a.d Technology Commis.ion of s.i La.ka. Gra.hica. a.s.ra.t

关键词： renewa.le energy energy s.ora.e green hydrogen s.s.a.na.le development goa.s s.i La.ka s.cia. economic environmenta. s.s.a.na.le a.forda.le

Genera.ized Hopf Bifurca.ion in a.Dela. Model of Neutrophil Cells.Model

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Interna.iona. Journa. of Modern Nonlinea. Theory a.d a.plica.ion 2024年第2期13卷 11-28页

作者： s.qi Ma.s. J. Hoga. Depa.tment of Ma.hema.ics China Agricultural University Beijing China Depa.tment of Ma.hema.ics University of Bristol Bristol UK

The DDE-Biftool s.ftwa.e is.a.plied to s.lve the dyna.ica. s.a.ility a.d bifurca.ion problem of the neutrophil cells.model. Ba.0}d on Hopf point finding with the s.a.ility property of the equilibrium s.lution los., the continua.ion of the bifurca.ing periodica. s.lution s.a.ting from Hopf point is.exploited. The genera.ized Hopf point is.tra.ked by s.eking for the critica. va.ue of free pa.a.eter of the s.itching phenomena.of the open loop, which des.ribes.the lineup of bifurca.ing periodica. s.lutions.from Hopf point. The norma. form nea. the genera.ized Hopf point is.computed by Lya.unov-s.himdt reduction s.heme combined with the center ma.ifold a.a.ytica. technique. The nea. dyna.ics.is.cla.0}ified by geometrica.ly different topologica. pha.0} portra.ts.

关键词： Genera.ized Hopf Bifurca.ion DDE-Biftool s.ftwa.e Norm Form

s.eep-ba.0}d neurona. os.illa.ions.a.0}a.phys.ologica. bioma.ker for a.zheimer's.dis.a.0}:is.night time the right time?

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Neura. Regenera.ion Res.a.ch 2024年第7期19卷 1417-1418页

作者： Jona.ha. Witton Erica.s.Bra.y Micha.l T.Cra.g Depa.tment of Clinica. a.d Biomedica. s.iences Faculty of Health and Life SciencesUniversity of ExeterExeterEnglandUK Gla.s.one Ins.itute for Neurologica. Dis.a.0} San FranciscoCAUSA s.hool of Ps.chology a.d Neuros.ience College of MedicalVeterinary and Life SciencesUniversity of GlasgowGlasgowScotlandUK

Dementia.is.a.deva.0}a.ing s.ndrome cha.a.terized by memory problems.confus.on,a.d beha.ior cha.ges.tha. prevent people from performing everyda. *** is.the lea.ing ca.s. of dependency a.d dis.bility a.ongs. older people,res.lting in a.globa. economic cos. of ~$1.3 *** 58 million people a.e currently a.flicted by dementia.worldwide,with a.zheimer s.dis.a.0}(a.) ca.s.ng mos.(60-70%) of thes. ca.0}s.

关键词： a.zheimer everyda. performing

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Effect of Eu3+,Bi3+,a.d Li+ doping on lumines.ent property of GdNbO4

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Journa. of Ra.e Ea.ths 2024年第1期42卷 66-75页

作者： s.W.Wi Y.s.Lee Depa.tment of Phys.cs.a.d Integra.ive Ins.itute of Ba.0}c s.iences Soongsil University

We inves.iga.ed the emis.ion properties.of Eu3+-doped GdNbO4-ba.0}d oxide phos.hors.a.ming a. improving the Eu3+emis.ion by codoping of Bi3+a.d Li+.Eu3+s.ngly doped,Eu3+a.d Bi3+doubly doped,a.d Eu3+,Bi3+,a.d Li+triply doped GdNbO4were prepa.ed us.ng a.high-tempera.ure s.lid-s.a.e rea.tion *** red-ora.ge emis.ions.from Eu3+in the s.ngly doped s.mples.a.e s.gnifica.tly improved by the codoping of Bi3+,ma.nly due to the energy tra.s.er from Bi3+to Eu3+.The a.ditiona. codoping of Li+is.found to increa.0} the Eu3+emis.ion *** improvement might be a.tributed to the increa.0} in the photolumines.ent qua.tum yield origina.ing from la.ger gra.n s.zes.a.d better crys.a.linity.a.deta.led a.a.ys.s.of the X-ra. diffra.tion pa.tern a.d the a.0}mmetric ra.io es.ima.ed from the photolumines.ence s.ectra.s.ow tha. the loca. la.tice environment a.ound Eu3+in GdNbO4does.not cha.ge s.gnifica.tly with the codoping of Bi3+a.d Li+.Our res.lts.indica.e tha. Li+doping is.a.promis.ng wa. to improve the emis.ion properties.of ra.e-ea.th ion-doped GdNbO4phos.hors.

关键词： Eu 3+ GdNbO 4 Codoping of Li + Photolumines.ence s.ns.tizer Ra.e ea.ths

a.hybrid ma.hine-lea.ning model for s.la. irra.ia.ce foreca.0}ing

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CLEa. ENERGY 2024年第1期8卷 100-110页

作者： a.ma.zooqi, a.eera.M. Ma.louf, Ma.er El-Fouly, Ta.ek H. M. Ka.zoura.is. Va.0}leios.E. El Mours., Moha.ed s. Chrys.kopoulos. Cons.a.tinos. V Kha.ifa.Univ Dept Ind & Syst Engn POB 127788 Abu Dhabi U Arab Emirates Kha.ifa.Univ a.u Dha.i Elect Engn & Comp Sci Dept Abu Dhabi U Arab Emirates Kha.ifa.Univ Dept Civil Infrastruct & Environm Engn POB 127788 Abu Dhabi U Arab Emirates Tech Univ Crete Sch Chem & Environm Engn Khania 73100 Greece

Nowca.0}ing a.d foreca.0}ing s.la. irra.ia.ce a.e vita. for the optima. prediction of grid-connected s.la. photovolta.c (PV) power pla.ts. Thes. pla.ts.fa.e opera.iona. cha.lenges.a.d s.heduling dis.a.ch difficulties.due to the fluctua.ing na.ure of their power output. a.0}the genera.ion ca.a.ity within the electric grid increa.0}s. a.cura.ely predicting this.output becomes.increa.0}ngly es.entia., es.ecia.ly given the ra.dom a.d non-linea. cha.a.teris.ics.of s.la. irra.ia.ce under va.ia.le wea.her conditions. This.s.udy pres.nts.a.novel prediction method for s.la. irra.ia.ce, which is.directly in correla.ion with PV power output, ta.geting both s.ort-term a.d medium-term foreca.0} horizons. Our propos.d hybrid fra.ework employs.a.fa.0} tra.na.le s.a.is.ica. lea.ning technique ba.0}d on the trunca.ed-regula.ized kernel ridge regres.ion model. The propos.d method excels.in foreca.0}ing s.la. irra.ia.ce, es.ecia.ly during highly intermittent wea.her periods. a.key s.rength of our model is.the incorpora.ion of multiple his.orica. wea.her pa.a.eters.a.0}inputs.to genera.e a.cura.e predictions.of future s.la. irra.ia.ce va.ues.in its.s.a.a.le fra.ework. We eva.ua.ed the performa.ce of our model us.ng da.a.s.ts.from both cloudy a.d s.nny da.s.in s.a.tle a.d Medford, Us. a.d compa.ed it a.a.ns. three foreca.0}ing models. pers.s.ence, modified 24-hour pers.s.ence a.d lea.0} s.ua.es. Ba.0}d on three widely a.cepted s.a.is.ica. performa.ce metrics.(root mea. s.ua.ed error, mea. a.s.lute error a.d coefficient of determina.ion), our hybrid model demons.ra.ed s.perior predictive a.cura.y in va.ying wea.her conditions.a.d foreca.0} horizons. a.novel prediction method for s.la. irra.ia.ce, ta.geting both s.ort-term a.d medium-term foreca.0} horizons. is.propos.d to improve PV power production. The hybrid fra.ework employs.a.fa.0} tra.na.le s.a.is.ica. lea.ning technique ba.0}d on the trunca.ed-regula.ized kernel ridge regres.ion model. Gra.hica. a.s.ra.t

关键词： s.la. power genera.ion kernel ridge regres.ion hybrid model foreca.0}ing Ba.TERY ENERGY-s.ORa.E POWER PV Ra.Ia.ION PREDICTION CELLs

Evolution of Vira. Loa. in Pa.ients.Infected with HIV-1 a. Point G Univers.ty Hos.ita.

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Open Journa. of Medica. Microbiology 2024年第1期14卷 66-76页

作者： a. Ma.ga.D. Kone D. M. Couliba.y a. M. Ba.a.ka.a. Tra.re s. s. Dia.ite I. I. Ma.ga.I. Kona.e a. I. Ma.ga Fa.ulty of Medicine a.d Odontos.oma.ology of Ba.a.o (FMOs. University of Science of Technical and Technology De Bamako Bamako Mali La.ora.ory of Medica. Biology a.d Hos.ita. Hygiene of Point-G Univers.ty Hos.ita. Bamako Mali Fa.ulty of Pha.ma.y of Ba.a.o (Fa.h) University of Science of Technical and Technology De Bamako Bamako Mali La.ora.ory of the Luxembourg Mother-Child Hos.ita. Bamako Mali Na.iona. Ins.itute of Public Hea.th Bamako Mali Na.iona. Ins.itute for Tra.ning in Hea.th s.iences Bamako Mali La.ora.ory of the Ka.i Univers.ty Hos.ita. Center Bamako Mali Infectious.a.d Tropica. Dis.a.0}s.Depa.tment of Point-G Univers.ty Hos.ita. Bamako Mali La.ora.ory of CHU Ga.riel Touré Bamako Mali

Introduction: HIV, the huma. immunodeficiency virus. is.the etiologica. a.ent of a.quired immunodeficiency s.ndrome (a.Ds.. The a.m of this.s.udy wa.0}to a.0}es. the evolution of the vira. loa. in pa.ients.under trea.ment. Methodology: This.wa.0}a.s.udy ca.ried out from July 2017 to June 2022 a. the Point G Univers.ty Hos.ita. la.ora.ory. The determina.ion of the vira. loa. of pa.ients.wa.0}ca.ried out by PCR on the a.OTT M2000s./rt pla.form. Res.lts. a.tota. of 129 pa.ients.infected with HIV-1, a.ed 19 to 72 yea.s.with a.mea. a.e of 40.05 yea.s.± 10.71;a.l on a.tiretrovira. chemothera.y. The fema.e gender predomina.ed a.ong our pa.ients. The mos. common trea.ment regimen wa.0}2INTI + 1INNTI with 72.9% followed by 2INTI + 1INI with 13.2%. a.0}for the combina.ions.of molecules. the combina.ion TDF + 3TC + EFV a.d TDF + 3TC + DTG predomina.ed, res.ectively 65.1% a.d 13.2%. 89.9% of our pa.ients.ha. undetecta.le viremia.a.ter 12 months.of trea.ment (p a. a.era.e vira. loa. which ha. evolved from 681315.65 copies.ml ± 1616908.484 to M0 a. 5742.36 copies./ml ± 35756.883 a. M12 (p Conclus.on: Genera.ly s.ea.ing, a.tiretrovira. trea.ment ha. contributed to controlling vira. loa.s. however the thera.eutic combina.ion TDF + 3TC + DTG ha. ma.e it pos.ible to obta.n more pa.ients.with undetecta.le viremia.ins.ea..

关键词： HIV-1 Trea.ment Vira. Loa. Point G Univers.ty Hos.ita.

Firs. evidence for chira. wobbling of tria.ia. nuclei

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Nuclea. s.ience a.d Techniques 2024年第7期35卷 4-7页

作者： s.Fra.endorf Depa.tment of Phys.cs.a.d a.0}ronomy University of Notre DameNotre DameIN 46556USA

Chira.ity(Greek“ha.dines.”)is.a.property of ma.y com-plex *** molecules.exis. in two forms.one being the mirror ima.e of the *** for our ha.ds.it is.impos.ible to ma.e the ima.es.identica. by a.s.ita.le *** two forms.a.e ca.led left-ha.ded a.d *** ha.e the s.me binding energy,beca.s. the electro-ma.netic intera.tion,which holds.the molecule together,does.not cha.ge under a.*** properties.tha. a.e ins.ns.tive to the geometry a.e a.s. the *** different geometry is.the rea.0}n why the left-ha.ded form turns.the pola.iza.ion pla.e of tra.s.itted light in one direction by s.me a.gle while the right-ha.ded form turns.it in the oppo-s.te direction by the s.me ***,the geometrica. differences.between the two s.ecies.ma. ha.e other *** two s.ecies.of the ca.von molecule s.own in Fig.1 ta.0}e quite differently.

关键词： turns Chira. mirror

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s.herica. Functions.on Fuzzy Lie Group

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a.va.ces.in Pure Ma.hema.ics 2024年第4期14卷 185-195页

作者： Murphy E. Egwe s.muel s. s.ngodele Depa.tment of Ma.hema.ics University of Ibadan Ibadan Nigeria

Let G be a.loca.ly compa.t Lie group a.d its.Lie a.gebra. We cons.der a.fuzzy a.a.ogue of G, denoted by ca.led a.fuzzy Lie group. s.herica. functions.on a.e cons.ructed a.d a.vers.on of the exis.ence res.lt of the Hel... 详细信息

关键词： Fuzzy s.herica. Function Fuzzy Lie Group Fuzzy Ma.ifolds

Tribologica. beha.ior of lubrica.t-impregna.ed porous.polyimide

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Friction 2024年第4期12卷 711-725页

作者： Jinba.g LI Ningning ZHOU Ja.et s.s.WONG s.hool of Mecha.ica. Engineering a.d Mecha.ics Ningbo UniversityNingbo 315211China Beijing Key La.ora.ory of Long-life Technology of Precis. Rota.ion a.d Tra.s.is.ion Mecha.is.s Beijing Institute of Control EngineeringBeijing 100029China Depa.tment of Mecha.ica. Engineering Imperial College LondonLondon SW72AZUK

Porous.ma.eria.s.impregna.ed with lubrica.ts.ca. be us.d in conditions.where limited lubrica.t is.*** this.work,three porous.polyimides.PPI)with different dens.ties.were ***(Pa.)impregna.ed PPI(iPPI)dis.s.were rubbed a.a.ns. s.eel a.d s.pphire *** opera.do obs.rva.ions.of the iPPI-s.pphire conta.ts.s.ow tha. oil is.relea.0}d under a. a.plied loa.,forming a.menis.us.a.ound *** a. the outlet is.crea.ed a. high s.iding *** a.ount of relea.0}d oil increa.0}s.with increa.0}ng PPI *** moduli,E*,es.ima.ed ba.0}d on the a.tua. conta.t s.ze s.ow tha. tra.ped oil in iPPIs.contributes.to loa. *** higher s.eeds.tribologica. rehydra.ion of the conta.t occurs.in low dens.ty iPPI,with tha. E*ris.s.with *** high dens.ty PPIs.high s.eeds.give a.cons.a.tly high E*which is.limited by the vis.oela.0}ic properties.of the PPI network a.d pos.ibly the ra.e of oil *** of iPPI-s.eel conta.ts.is.governed by the mecha.ica. properties.of the PPI,the flow of the lubrica.t,a.d the roughnes. of the PPI *** low-a.d medium-dens.ty(highly porous.high roughnes.)PPIs.la.ge a.ount of oil is.relea.0}d,a.d lubrica.ion is.ma.nly via.lubrica.t res.ricted in the conta.t in the pores.a.d pos.ibly tribologica. *** high dens.ty(low poros.ty)PPI,with lower roughnes.,hydrodyna.ic lubrica.ion is.a.hieved which gives.the lowes. *** res.lts.s.ow tha. polymeric porous.ma.eria.s.for effective lubrica.ion require the optimiza.ion of its.s.rfa.e roughnes.,s.iffnes.,oil flow,a.d oil retentions.

关键词： polyimide porous.ma.eria. friction mecha.is. polymer limited lubrica.ion