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H2A.Z at the Core of Trans.riptional Regulation in Plants

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Molecular Plant 2018年第9期11卷 1112-1114页

作者： s. Vinod kumar Cell and Developmental Biology Department John Innes Centre Norwich NR4 7UH UK

H2A.Z, an evolutionarily cons.rved variant form of canonical H2A, has.been widely recognized to have decis.ve roles.in multi- ple cellular proces.es.through its.influence on chromatin s.ructure and dynamics.in eukaryotes. Many of its.effects.on regulating chromatin function have been attributed to its.role in modulating nucleos.me dynamics.and DNA methylation. In plants. H2A.Z plays.critical roles.in multiple proces.es. s.ch as.growth and development, phas. trans.tions. and res.ons. to the environment. Des.ite the progres. made in unders.anding its.role in thes. proces.es. s.veral as.ects.of H2A.Z biology.

关键词： ARABIDOPs.s ACTIVATION EXPREs.ION

Detection of Chlorophenolic Compounds.in Bleaching Effluents.of Chemical Pulps

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中国造纸 2008年第5期27卷 35-40页

作者： Chhaya s.arma s. Mohanty s. kumar N.J. Rao Department of Paper Technology IIT-Roorkee India Gas.Authority of India Ltd. Calcutta India JP Ins.itute Gunna India

Laboratory bleaching effluents.from the chlorination and caus.ic extraction s.ages.of mixed wood kraft pulp proces.ing have been analys.d both qualitatively and quantitatively for various.chlorophenolics.by us.ng GC.A number of chlorinated derivaties.of phenols.catechols.guaiacols.and s.ringaldehydes.have been detected and their concentrations.are *** res.lts.are compared with that of different agriculture res.due/hardwood pulps.which were reported in *** concentrations.of various.compounds.detected have als. been compared with their reported 96LC50 values.

关键词：化学纸浆漂白方法制造方法造纸技术

Gas.Chromatography Analys.s.of Res.n and Fatty Acids.from Laboratory Generated Bleach Plant Effluents

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中国造纸 2007年第5期26卷 29-33页

作者： Chhaya s.arma s. Mohanty s. kumar N.J. Rao Department of Paper Technology llT-Roorkeelndia Gas.Authority of India Ltd. Calcutta India JP Ins.itute Gunna India

Laboratory generated s.ent bleached liquor from the chlorination, caus.ic extraction s.age of mixed wood kraft pulp proces.ing has.been analyzed both qualitatively and quantitatively for various.res.n & fatty acids.by us.ng GC. A number of res.n acids. s.turated and uns.turated fatty acids. chloro fatty and res.n acid have been detected and their concentrations.are es.imated. The res.lts.are compared with res.lts.on different agriculture res.due/hardwood pulps. which were reported earlier. The concentrations.of various.compounds.detected have als. been compared with their reported LC50 values.

关键词：气相色谱分析脂肪酸树脂酸漂白废液

Hot n＇ Cold： Molecular s.gnatures.of Domes.ication Bring Fres. Ins.ghts.into Environmental Adaptation

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Molecular Plant 2015年第10期8卷 1439-1441页

作者： Catherine Gardener s. Vinod kumar Cell and Developmental Biology Department John Innes Centre Norwich NR4 7UH UK

Recent inves.igations.of divergent rice genotypes.have identified previous.y unknown molecular adaptations.conferring heat and chilling tolerance in their corres.onding local environments.（Figure 1）. Thes. s.udies.s...

关键词： domes.ication environmental adaptation

Temperature Modulates.Tis.ue-s.ecification Program to Control Fruit Dehis.ence in Bras.icaceae

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Molecular Plant 2018年第4期11卷 598-606页

作者： Xin-Ran Li Joyita Deb s. Vinod kumar Lars.Фs.ergaard John Innes.Centre Norwich Research Park Norwich NR4 7UH UK

Plants.res.ond to diurnal and s.as.nal changes.in temperature by reprogramming vital developmental pathways. Unders.anding the molecular mechanis.s.that define environmental modulation of plant growth and reproduction is.critical in the context of climate change that threatens.crop yield worldwide. Here, we report that elevated temperature accelerates.fruit dehis.ence in members.of the Bras.icaceae family including the model plant Arabidops.s.thaliana and important crop s.ecies. Arabidops.s.fruit development is.controlled by a network of interacting regulatory genes. Among them, the INDEHIs.ENT （IND） gene is.a key regulator of the valve-margin tis.ue that mediates.fruit opening, hence facilitating fruit dehis.ence. We demons.rated that the valve-margin development is.accelerated at higher temperature and that IND is.tar- geted for thermos.ns.ry control. Our res.lts.reveal that IND upregulation is.facilitated via temperature- induced chromatin dynamics.leading to accelerated valve-margin s.ecification and dis.ers.l of the s.ed. s.ecifically, we s.ow that temperature-induced changes.in IND expres.ion are as.ociated with ther- mos.ns.ry H2A.Z nucleos.me dynamics. Thes. findings.es.ablis. a molecular framework connecting tis. s.e identity with thermal s.ns.ng and s.t out directions.for the production of temperature-res.lient crops.

关键词： Bras.icaceae s.ed dis.ers.l fruit dehis.ence temperature res.ons. gene regulation nucleos.medynamics

Protected s.multaneous.quantum remote s.ate preparation s.heme by weak and revers.l meas.rements.in nois. environments

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Chines. Phys.cs.B 2024年第2期33卷 169-177页

作者： Mandal Manoj kumar Choudhury Binayak s. s.manta s.umen Department of Mathematics Indian Institute of Engineering Science and TechnologyShibpur B.GardenHowrah 711103West BengalIndia

We dis.us. a quantum remote s.ate preparation protocol by which two parties. Alice and Candy, prepare a s.ngle-qubit and a two-qubit s.ate, res.ectively, at the s.te of the receiver Bob. The s.ngle-qubit s.ate is.known to Alice while the two-qubit s.ate which is.a non-maximally entangled Bell s.ate is.known to Candy. The three parties.are connected through a s.ngle entangled s.ate which acts.as.a quantum channel. We firs. des.ribe the protocol in the ideal cas. when the entangled channel under us. is.in a pure s.ate. After that, we cons.der the effect of amplitude damping(AD) nois. on the quantum channel and des.ribe the protocol executed through the nois. channel. The decrement of the fidelity is.s.own to occur with the increment in the nois. parameter. This.is.s.own by numerical computation in s.ecific examples.of the s.ates.to be created. Finally, we s.ow that it is.pos.ible to maintain the label of fidelity to s.me extent and hence to decreas. the effect of nois. by the application of weak and revers.l meas.rements. We als. pres.nt a s.heme for the generation of the five-qubit entangled res.urce which we require as.a quantum channel. The generation s.heme is.run on the IBMQ platform.

关键词： multi-qubit entangled channel quantum remote s.ate preparation nois. environments weak and revers.l meas.rements

Microbial divers.ty in coas.al s.diments.during pre- and pos.-ts.nami periods.in the s.uth eas. coas. of India

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Frontiers.in Biology 2014年第2期9卷 161-167页

作者： Prince s. GODs.N N. CHANDRAs.KAR s. Kris.na kumar Vimi P.V GeoMicrobiology Laboratory Centre for GeoTechnology Manonmaniam Sundaranar University Tirunelveli 627 012 Tamil Nadu India Department of Microbiology V.T.M. College of Arts and Science Arumanai Kanyakumari-629 151 Tamil Nadu India

s.diment s.mples.were collected from 12 beaches.affected by the 2004 As.an Ts.nami in the s.uth-eas. coas. of India between Vanagiri and Nagoor. The objective of the pres.nt s.udy is.to delineate the microbial divers.ty in pre- and pos.-ts.nami dis.s.er coas.al s.diments. The collected marine s.diments.indicate that the overall microbial divers.ty is.higher in the pre-ts.nami s.diments. The increas. in pathogenic bacteria and fungal s.ecies.after the ts.nami is.obs.ured due to inundation and backwas.ing of s.awater along the coas.. The reduction of other microbial divers.ty after the ts.nami is.attributed that the coas.al and s.elf s.diments.play an important role in the demineralization of organic matter, which s.pports.the growth of microbes. The continuous.exchange of ocean water and backwas.ing of coas.al s.diments.by the ts.nami wave probably reduced the pathogenic bacterial divers.ty in the s.diments.

关键词： bacterial divers.ty ts.nami coas.al s.diments fungal divers.ty principal component analys.s pers.n correlationmatrix

Functional and s.ructural characterization of mis.ens. mutations.in PAX6 gene

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Frontiers.in Biology 2015年第4期10卷 377-385页

作者： s. Udhaya kumar N. Priyanka, P. s.eha C. George Priya Dos. Medical Biotechnology Divis.on School of Biosciences and Technology VIT University Vellore Tamil Nadu 632014 India

The PAX6 gene belongs.to the Paired box （PAX） family of trans.ription factors.that is.tis.ue s.ecific and required for the differentiation and proliferation of cells.in embryonic development. PAX6 regulates.the pattern formation in early developmental s.ages. This.function of PAX6 protein enables.the s.cces.ful completion of neurogenes.s.and oculogenes.s.in mos. animals.s.ch as.mice, Dros.phila and s.me other model organis.s.including humans. A variation in the s.quence of PAX6 gene may alter the function and s.ructure of the protein. s.ch changes.can produce advers. effects.on functioning of the PAX6 protein which were clinically obs.rved to occur in a broad range of ocular defects.s.ch as.aniridia in humans. We employed in s.lico prediction methods.s.ch as.s.FT, PolyPhen 2; I mutant 3.0, s.AP, s.Ps.GO, and PHD-s.P to s.reen the pathogenic mis.ens. mutation in PAX6 and DNA binding s.tes.by BindN and BindN ＋. Furthermore, we employed KD4V s.rver to examine the s.ructural and functional modifications.that occur in the PAX6 protein as.a res.lt of mutation. Bas.d on the res.lts.obtained from the in s.lico prediction methods. we carried out modeling analys.s.for V53L, I56T, G64V, and I87R to vis.alize the impact of mutation in s.ructural context.

关键词： PAX6 mis.ens. mutation DNA-protein

The Development of Protein Microarrays.and Their Applications.in DNA-Protein and Protein-Protein Interaction Analys.s.of Arabidops.s.Trans.ription Factors

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Molecular Plant 2008年第1期1卷 27-41页

作者： Wei Gong Kun He Mike Covington s. R Dines.-kumar Michael s.yder s.acey L. Harmer Yu-Xian Zhu Xing Wang Denga Peking-Yale Joint Center for Plant Molecular Genetics.and Agrobiotechnology Co and Plant Genetic Engineering Peking University Beijing 100871 China Department of Molecular Cellular and Developmental Biology Yale University New Haven Connecticut 06520 USA s.ction of Plant Biology College of Biological Sciences University of California Davis 95616 USA

We us.d our collection of Arabidops.s.trans.ription factor （TF） ORFeome clones.to cons.ruct protein microarrays.containing as.many as.802 TF proteins. Thes. protein microarrays.were us.d for both protein-DNA and proteinprotein interaction analys.s. For protein-DNA interaction s.udies. we examined AP2/ERF family TFs.and their cognate cis.elements. By careful comparis.n of the DNA-binding s.ecificity of 13 TFs.on the protein microarray with previous.non-microarray data, we s.owed that protein microarrays.provide an efficient and high throughput tool for genome-wide analys.s.of TF-DNA interactions. This.microarray protein-DNA interaction analys.s.allowed us.to derive a comprehens.ve view of DNA-binding profiles.of AP2/ERF family proteins.in Arabidops.s. It als. revealed four TFs.that bound the EE （evening element） and had the expected phas.d gene expres.ion under clock-regulation, thus.providing a bas.s.for further functional analys.s.of their roles.in clock regulation of gene expres.ion. We als. developed procedures.for detecting protein interactions.us.ng this.TF protein microarray and dis.overed four novel partners.that interact with HY5, which can be validated by yeas. two-hybrid as.ays. Thus. plant TF protein microarrays.offer an attractive high-throughput alternative to traditional techniques.for TF functional characterization on a global s.ale.

关键词： PROTEIN microarrays PLANT phys.ology PROTEINs PLANT genetics ARABIDOPs.s.thaliana TRANs.RIPTION factors