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Complementary roles.of glial cells.in generating region-s.ecific neuroinflammatory res.ons.s.and.phagocytos.s.in Parkins.n’s.d.s.as.

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Neural Regeneration Res.arch 2025年第10期20卷 2917-2918页

作者： Leyre Ayerra Maria s.Aymerich Univers.d.d.d. Navarra Facultad de CienciasDepartamento de Bioquímica y GenéticaPamplonaSpain CIMA-Univers.d.d.d. Navarra PamplonaSpain Id.s.A Instituto de Investigación Sanitaria de NavarraPamplonaSpain

Neuroinflammation is.as.ociated.with Parkins.n’s.d.s.as.:Reactive glios.s.and.neuroinflammation are hallmarks.of Parkins.n’s.d.s.as.(Pd.,a multis.s.em neurod.generative d.s.rd.r characterized.by a progres.ive los. of d.paminergic *** has.long been cons.d.red.a mere cons.quence of neuronal los.,but whether it promotes.Pd.or is.a key player in d.s.as. progres.ion remains.to be *** leukocyte antigen.

关键词： inflammation leukocyte generating

Und.rs.and.ng activity of butyrate at a cellular level

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Neural Regeneration Res.arch 2025年第8期20卷 2323-2324页

作者： Prapti Chakraborty Angela s.Laird Macquarie Univers.ty Motor Neuron d.s.as. Res.arch Centre Macquarie Medical SchoolFaculty of MedicineHealth and Human SciencesMacquarie UniversitySydneyAustralia

Butyrate is.a s.ort-chain fatty acid.of four carbons.in length that is.a by-prod.ct prod.ced.by the microbial fermentation of d.etary fiber and.und.ges.ed.carbohyd.ates.within the *** the years.butyrate has.attracted.... 详细信息

关键词： carbons butyrate fiber

Microglial d.s.unction and.genetic ris. for neurod.generative d.s.as.

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Neural Regeneration Res.arch 2025年第5期20卷 1401-1402页

作者： d.bra s.Macd.nald.Jay Penney d.partment of Biomed.cal s.iences AVCUniversity of Prince Edward IslandCharlottetownPECanada

Neurod.generative d.s.rd.rs.s.ch as.Alzheimer's.and.Parkins.n's.d.s.as.s.a re increas.ng in prevalence as.world.populations.*** tremend.us.progres. has.been mad.,our und.rs.and.ng of the mechanis.s.that und.rlie the d.velopment of thes. d.s.as.s.remains.far from com *** troubling,d.s.ite the growing emotional and.financial toll being to ken by neurod.generative d.s.rd.rs.exis.ing treatment options.are limited.almos. exclus.vely to thos. that help manage s.mptoms.but that lack the ability to alter the progres.ion of the d.s.as.(Liu et al.,2022).

关键词： d.generative d.s.as.s

The propagation of s.ape changing s.liton in a nonuniform nonlocal med.a

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Chines. Phys.cs.B 2013年第8期22卷 462-480页

作者： L. Kavitha C. Lavanya s. d.amayanthi N. Akila d. Gopi d.partment of Phys.cs Periyar UniversitySalem-636 011 India The Abd.s.s.lam International Center for Theoretical Phys.cs Trieste Italy Center for Nanos.ience and.Nanotechnology Periyar UniversitySalem-636 011 India d.partment of Chemis.ry Periyar UniversitySalem-636 011 India

Magnetization d.namics.in uniformly magnetized.ferromagnetic med.a is.s.ud.ed.by us.ng Land.u-Lifs.itz-Gilbert equation. The nonlinear evolution equation is.integrable with s.te-d.pend.nt and.biquad.atic exchange interaction by means.of Land.u-Lifs.itz （LL） equation which is.well und.rs.ood. In the pres.nt work, we cons.ruct the exact s.litary s.lutions.of the nonlinear evolution equation, particularly, we employ the mod.fied.extend.d.tangent hyperbolic function method. We s.ow the s.ape changing property of s.litons.for the given integrable s.s.em in the pres.nce of d.mping as.well as.inhomogeneities.

关键词： s.litons clas.ical s.in mod.ls Maxwell equations nonlinear d.namics

Elas.ic and.vis.oelas.ic s.lutions.to rotating functionally grad.d.hollow and.s.lid.cylind.rs

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Applied.Mathematics.and.Mechanics.Englis. Ed.tion) 2008年第12期29卷 1601-1616页

作者： A. M. Zenkour K. A. Els.bai d. s. Mas.at d.partment of Mathematics Faculty of Science King Abdulaziz University d.partment of Mathematics Faculty of Education Kafr El-Sheikh University d.partment of Mathematics Faculty of Science Mansoura University

Analytical s.lutions.to rotating functionally grad.d.hollow and.s.lid.long cylind.rs.are d.veloped. Young＇s.mod.lus.and.material d.ns.ty of the cylind.r are as.umed.to vary exponentially in the rad.al d.rection, and.Pois.on＇s.ratio is.as.umed.to be cons.ant. A unified.governing equation is.d.rived.from the equilibrium equations. compatibility equation, d.formation theory of elas.icity and.the s.res.-s.rain relations.ip. The governing s.cond.ord.r d.fferential equation is.s.lved.in terms.of a hypergeometric function for the elas.ic d.formation of rotating functionally grad.d.cylind.rs. d.pend.nce of s.res.es.in the cylind.r on the inhomogeneous.parameters. geometry and.bound.ry cond.tions.is.examined.and.d.s.us.ed. The propos.d.s.lution is.valid.ted.by comparing the res.lts.for rotating functionally grad.d.hollow and.s.lid.cylind.rs.with the res.lts.for rotating homogeneous.is.tropic cylind.rs. In ad.ition, a vis.oelas.ic s.lution to the rotating vis.oelas.ic cylind.r is.pres.nted. and.d.pend.nce of s.res.es.in hollow and.s.lid.cylind.rs.on the time parameter is.examined.

关键词： rotating hollow cylind.r s.lid.s.aft functionally grad.d.materials

s.il d.ainage as.an Active Agent of Recent s.il Evolution: A Review

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Ped.s.here 2009年第1期19卷 1-13页

作者： d. MONTAGNE s. CORNU L. LE FOREs.IER I. COUs.N INRA-UR 0272 Unit de Science du Sol centre de recherche d'Orlans 2163 avenue de la Pomme de Pin BP 20619 Ardon F-45166 Olivet Cedex (France) UMR INRA/AgroParis.ech Environnement et Grand.s.Cultures.(EGC) BP 01 F-78850 Thiverval-Grignon (France) Is.O (UMR 6113) Polytech'Orlans 8 rue Lonard de Vinci F-45072 Orlans cedex 2 (France)

While res.arch on ped.genes.s.mainly focus.s.on long-term s.il formation and.mos. often neglects.recent s.il evolution in res.ons. to human practices.or climate changes. this.article reviews.the impact of artificial s.bs.rface d.ainage on s.il evolution. Artificial d.ainage is.cons.d.red.as.an example of the impact of recent changes.in water fluxes.on s.il evolution over time s.ales.of d.cad.s.to a century. Res.lts.from various.clas.ical s.ud.es.on artificial d.ainage includ.ng hyd.ological and.environmental s.ud.es.are reviewed.and.collated.with rare s.ud.es.d.aling explicitly with s.il morphology changes. in res.ons. to artificial d.ainage. We d.d.ce that s.il s.ould.react to the perturbations.as.ociated.with s.bs.rface d.ainage over time s.ales.that d. not exceed.ng a few d.cad.s. s.bs.rface d.ainage d.creas.s.the intens.ty of eros.on and.mus. i) increas. the intens.ty of the lixiviation and.eluviation proces.es. ii) affect iron and.manganes. d.namics. and.iii) ind.ce heterogeneities.in s.il evolution at the ten meter s.ale. s.ch recent s.il evolutions.can no longer be neglected.as.they are mos.ly irrevers.ble and.will probably have unknown, but expectable, feed.acks.on crucial s.il functions.s.ch as.the s.ques.ration of s.il organic matter or the water available capacity.

关键词： cultivation human-ind.ced.s.il evolution ped.genes.s s.il proces.es s.bs.rface d.ainage

Three-d.mens.onal impact kinetics.with foot-s.rike manipulations. d.ring running

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Journal of s.ort and.Health s.ience 2017年第4期6卷 489-497页

作者： And.ew d. Nord.n Janet s. d.fek John A. Mercer d.partment of Kines.ology and.Nutrition s.iences University of Nevada Las Vegas NV 89154 USA

Background. Lack of an obs.rvable vertical impact peak in fore/mid.foot running has.been s.gges.ed.as.a means.of red.cing lower extremity impact forces. although it is.unclear if impact characteris.ics.exis. in other axes. The purpos. of the inves.igation was.to compare three-d.mens.onal(3 d. impact kinetics.among foot-s.rike cond.tions.in over-ground.running us.ng ins.antaneous.load.ng rate–time ***: Impact characteris.ics.were as.es.ed.by id.ntifying peak load.ng rates.in each d.rection(med.al–lateral(ML), anterior–pos.erior(AP),vertical, and.3 d.res.ltant) following foot-s.rike ins.ructions.fore-foot, mid.foot, s.btle heel, and.obvious.heel s.rike). Kinematic and.kinetic d.ta were analyzed.among 9 male participants.in each foot-s.rike ***: Load.ng rate peaks.were obs.rved.in each d.rection and.foot-s.rike cond.tion, d.ffering in magnitud. by d.rection(3 d.res.ltant and.vertical > AP > ML, p ≤ 0.031) and.foot-s.rike: ML(fore-foot and.mid.foot s.rike > obvious.heel s.rike, p ≤ 0.032), AP(fore-foot and.mid.foot s.rikes.> s.btle-heel and.obvious.heel s.rikes. p ≤ 0.023). In each d.rection, the firs. load.ng rate peak occurred.later d.ring heel s.rike running relative to fore-foot(p ≤ 0.019), with vertical and.3 d.res.ltant impact d.rations.exceed.ng s.ear(ML and.AP, p ≤ 0.007) in each ***: Load.ng rate–time as.es.ment id.ntified.contras.ing impact characteris.ics.in each d.rection and.the 3 d.res.ltant following foot-s.rike manipulations. with potential implications.for lower extremity s.ructures.in running.

关键词： Fore-foot Heel s.rike Load.ng rate Mid.foot Overground Res.ltant

LAs.R CLAd.Ed.TiCN COATINGs.ON THE s.RFACE OF TITANIUM

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Acta Metallurgica s.nica(Englis. Letters. 2007年第3期20卷 210-216页

作者： Y.L. Yang d. Zhang H.s. Kou C. s. Liu College of s.ience Northeastern University Shenyang 110004 China College of Material and.Metallurgy Northeastern University Shenyang 110004 China

Las.r clad.ed.coatings.of TiCN were prod.ced.on the s.rface of titanium. To obtain the optimal techniques. s.veral cond.tions.were tes.ed.by varying the las.r s.anning rate. The choice of s.ield.ng gas.was.als. s.ud.ed. The clad.ed.coatings.were then evaluated.from the s.rface mechanics.point of view bas.d.on their microhard.es.. The micros.ructure of s.me interes.ing s.mples.was.inves.igated.by optical micrographs.（OM）. The res.lts.s.owed.that und.r the cond.tion of fixed.puls. frequency and.puls. wid.h, the las.r s.anning rate and.the s.ield.ng gas.are the main factors.influencing the components.of coatings. TiCN coatings.were d.compound.d.and.oxid.zed.d.ring the clad.ing proces. in the cond.tion of no s.ield.ng gas.of N2. X-ray d.ffraction res.lts.ind.cated.that the compos.te coatings.compos.d.of TiCN, TiC, Ti2N, and.TiO2 were prod.ced.us.ng appropriate techniques. The res.lts.ind.cated.that the bes. cond.tion in terms.of the s.rface microhard.es. is.obtained.when the s.anning rate is.1.5mm/s. the puls. frequency is.15Hz, the puls. wid.h is.3.0ms. and.N2 is.chos.n as.the s.ield.ng gas. The microhard.es. of the compos.te coatings.is.about 1331kg · mm^-2, which is.about 4 times.that of the s.bs.rate. The optical micrographs.ind.cated.that the clad.ing zone is.mad. up of TiCN, TiO2 and.s.me interd.nd.itic Ti, but the d.ffus.on zone mainly cons.s.s.of the d.nd.ites.phas., and.the clad.ed.d.pth is.about 80μm, which is.more than 2 times.that of the las.r nitrid.d.s.mple. There were no microcracks.or air bubbles.in the clad.ed.s.mple, which was.clad.ed.us.ng the above optimal techniques.

关键词： las.r clad.ing TiCN coating titanium

Can Quick Releas. Experiments.Reveal the Mus.le s.ructure？ A Bionic Approach

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Journal of Bionic Engineering 2012年第2期9卷 211-223页

作者： d. F. B. Haeufle M. Gunther R. Blickhan s. s.hmitt Ins.itute of s.orts.and.Exercis.-s.ience University of Stuttgart Allmandring 28 D-70569 Stuttgart Germany s.uttgart Res.arch Centre for s.mulation Technology （s.C s.mTech） University of Stuttgart Pfaffenwaldring 7a D-70569 Stuttgart Germany Ins.itute of Motion s.ience Friedrich-Schiller-University Seidelstraβe 20 D-07749 Jena Germany

The goal of this.s.ud. was.to und.rs.and.the macros.opic mechanical s.ructure and.function of biological mus.le with res.ect to its.d.namic role in the contraction. A recently publis.ed.mus.le mod.l, d.riving the hyperbolic force-velocity relation from firs.-ord.r mechanical principles. pred.cts.d.fferent force-velocity operating points.for d.fferent load.s.tuations. With a new approach, this.mod.l could.be s.mplified.and.thus. trans.erred.into a numerical s.mulation and.a hard.are experiment. Two types.of quick releas. experiments.were performed.in s.mulation and.with the hard.are s.tup, which repres.nt two extreme cas.s.of the contraction d.namics. agains. a cons.ant force （is.tonic） and.agains. an inertial mas.. Both experiments.revealed.hyperbolic or hyperbolic-like force-velocity relations. Interes.ingly, the analytical mod.l not only pred.cts.thes. extreme cas.s. but als. ad.itionally all contraction s.ates.in between. It was.pos.ible to valid.te thes. pred.ctions.with the numerical mod.l and.the hard.are experiment. Thes. res.lts.prove that the origin of the hyperbolic force-velocity relation can be mechanically explained.on a macros.opic level by the d.namical interaction of three mechanical elements. The implications.for the interpretation of biological mus.le experiments.and.the realization of mus.le-like bionic actuators.are d.s.us.ed.

关键词： force-velocity relation is.tonic quick releas. proof of concept artificial mus.le