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Neural Regeneration Res.arch 2025年第2期20卷 366-377页

作者： samuel Abokyi d.nnis.Yan-yin Ts. s.hool of Optometry The Hong Kong Polytechnic UniversityKowloonHong Kong Special Administrative RegionChina Res.arch Center for s.ARP Vis.on The Hong Kong Polytechnic UniversityKowloonHong Kong Special Administrative RegionChina Center for Eye and.Vis.on Res.arch Sha TinHong Kong Special Administrative RegionChina

Retinal aging has.been recognized.as.a s.gnificant ris. factor for various.retinal d.s.rd.rs.includ.ng d.abetic retinopathy,age-related.macular d.generation,and.glaucoma,following a growing und.rs.and.ng of the molecular und.rpinnings.of their *** comprehens.ve review explores.the mechanis.s.of retinal aging and.inves.igates.potential neuroprotective approaches.focus.ng on the activation of trans.ription factor *** meta-analys.s.have d.mons.rated.promis.ng outcomes.of trans.ription factor EB-targeted.s.rategies.s.ch as.exercis.,calorie res.riction,rapamycin,and.metformin,in patients.and.animal mod.ls.of thes. common retinal *** review critically as.es.es.the role of trans.ription factor EB in retinal biology d.ring aging,its.neuroprotective effects.and.its.therapeutic potential for retinal *** impact of trans.ription factor EB on retinal aging is.cell-s.ecific,influencing metabolic reprogramming and.energy homeos.as.s.in retinal neurons.through the regulation of mitochond.ial quality control and.nutrient-s.ns.ng *** vas.ular end.thelial cells.trans.ription factor EB controls.important proces.es.includ.ng end.thelial cell proliferation,end.thelial tube formation,and.nitric oxid. levels.thereby influencing the inner blood.retinal barrier,angiogenes.s.and.retinal ***,trans.ription factor EB affects.vas.ular s.ooth mus.le cells.inhibiting vas.ular calcification and.*** retinal pigment epithelial cells.trans.ription factor EB mod.lates.functions.s.ch as.autophagy,lys.s.mal d.namics.and.clearance of the aging pigment lipofus.in,thereby promoting photoreceptor s.rvival and.regulating vas.ular end.thelial growth factor A expres.ion involved.in *** cell-s.ecific functions.of trans.ription factor EB s.gnificantly impact retinal aging mechanis.s.encompas.ing proteos.as.s.neuronal s.naps. plas.icity,energy metabolis.,microvas.ulature,and.inflammation,ultimately offering pro

关键词： age-related.macular d.generation anti-aging interventions autophagy calorie res.riction d.abetic retinopathy exercis. glaucoma neuromod.lation phagocytos.s photoreceptor outer s.gment d.grad.tion retinal aging trans.ription factor EB

A comprehens.ve inves.igation on nonlinear vibration and.bend.ng characteris.ics.of bio-ins.ired.helicoid.l laminated.compos.te s.ructures

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Applied.Mathematics.and.Mechanics.Englis. Ed.tion) 2025年第1期46卷 81-100页

作者： s.s.URABH R.KIRAN d.s.NGH R.VAIs. V.s.CHAUHAN s.hool of Mechanical and.Materials.Engineering Indian Institute of Technology Mandi

Bio-ins.ired.helicoid.l compos.te laminates. ins.ired.by the intricate helical s.ructures.found.in nature, pres.nt a promis.ng frontier for enhancing the mechanical properties.of s.ructural d.s.gns. Hence, this.s.ud. provid.s.a comprehens.ve inves.igation into the nonlinear free vibration and.nonlinear bend.ng behavior of bio-ins.ired.compos.te plates. The invers. hyperbolic s.ear d.formation theory(IHs.T) of plates.is.employed.to characterize the d.s.lacement field. with the incorporation of Green-Lagrange nonlinearity. The problem is.mod.led.us.ng the C0finite element method.FEM), and.an in-hous. cod. is.d.veloped.in the MATLAB environment to s.lve it numerically. Various.helicoid.l layup configurations.includ.ng helicoid.l recurs.ve(HR), helicoid.l exponential(HE), helicoid.l s.mi-circular(Hs., linear helicoid.l(LH), and.Fibonacci helicoid.l(FH)with d.fferent layup s.quences.and.quas.-is.tropic configurations.are s.ud.ed. The mod.l is.valid.ted. and.parametric s.ud.es.are cond.cted. Thes. s.ud.es.inves.igate the effects.of layup configurations. s.d.-to-thicknes. ratio, mod.lus.ratios. bound.ry cond.tions. and.load.ng cond.tions.at d.fferent load.amplitud.s.on the nonlinear vibration and.nonlinear bend.ng behaviors.of bio-ins.ired.compos.te plates. The res.lts.s.ow that the laminate s.quence exerts.a s.bs.antial impact on both nonlinear natural frequencies.and.nonlinear bend.ng behaviors. Moreover, this.influence varies.acros. d.fferent s.d.-to-thicknes. ratios.and.bound.ry cond.tions.of the bio-ins.ired.compos.te plate.

关键词： finite element method.(FEM) nonlinear Green-Lagrange invers. hyperbolic s.ear d.formation theory (IHs.T) bio-ins.ired.compos.te plate helicoid.l O322

Performance of Chemical Vapor d.pos.ted.Boron-d.ped.AlN Thin Film as.Thermal Interface Materials.for 3-W LEd. Thermal and.Optical Analys.s

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Acta Metallurgica s.nica(Englis. Letters. 2018年第1期31卷 97-104页

作者： s. s.anmugan d. Mutharas. Nano Optoelectronics.Res.arch Laboratory School of Physics Universiti Sains Malaysia (USM) 11800 Minden Pulau Pinang Malaysia

Boron-d.ped.aluminum nitrid. （B-AlN） thin films.were s.nthes.zed.on Al s.bs.rates.by us.ng chemical vapor d.pos.tion method.by changing the s.nthes.s.parameters.and.were us.d.as.thermal interface material for high power light emitting d.od. （LEd.. The B-AlN thin film-coated.Al s.bs.rate was.us.d.as.heat s.nk and.s.ud.ed.the performance of high power LEd.at various.d.iving currents. The record.d.trans.ent cooling curve was.evaluated.to s.ud. the ris. in junction temperature （Tj）, total thermal res.s.ance （gth_tot） and.the s.bs.rate thermal res.s.ance （Rth_s.b） of the given LEd. From the res.lts. the B-AlN thin film （prepared.at proces. 4） interfaced.LEd.s.owed.low Rth-tot and.Tj value for all d.iving currents.and.obs.rved.high d.fference in Rth_tot （△Rth_tot =2.2 K/W） at 700 mA when compared.with the Rth-tot of LEd.attached.on bare Al s.bs.rates.（LEd.Al）. The Tj of LEd.was.red.ced.cons.d.rably and.obs.rved.4.7 ℃ as.ATj for the film prepared.us.ng proces. 4 cond.tion when compared.with LEd.Al bound.ry cond.tion at 700 mA. The optical performance of LEd.was.als. tes.ed.for all bound.ry cond.tions.and.s.owed.improved.lux values.for the given LEd.at 700 mA where B-AlN thin film was.s.nthes.zed.us.ng optimized.flow of Al, B and.N s.urces.with minimized.B and.N content. The other optical parameters.s.ch as.color correlated.temperature and.color rend.ring ind.x were als. meas.red.and.obs.rved.low d.fference for all bound.ry cond.tions. The obs.rved.res.lts.are s.gges.ed.to us. B-AlN thin film as.efficient s.lid.thin film thermal interface materials.in high power LEd.

关键词： Light emitting d.od. (LEd. B-AIN thin film Chemical vapor d.pos.tion (CVd. Thermal trans.ent analys.s Junction temperature Optical performance

Non-Uniform Axial Electric Field.in Argon Glow d.s.harge Plas.a

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Chines. Phys.cs.Letters 2006年第5期23卷 1234-1237页

作者： d. Akbar s. Bilikmen d.partment of Phys.cs Middle East Technical University 06531 Ankara Turkey

The non-uniform argon d. glow d.s.harge plas.a s.s.em has.been cons.ructed.in a very s.ecial d.s.gn to inves.igate the effects.of variable tube rad.us.on plas.a parameters. By us.ng is.lated.computer controlled.three couples.of a d.uble probe （TCd.） s.s.em, the electron temperature, electron d.ns.ty, the red.ced.electric field. and.electron d.ift velocity are meas.red.at low and.intermed.ate pres.ures. It is.s.own that the electron temperature and.red.ced.electric field.（d.ns.ty） d.creas.s.（increas.s. as.the rad.us.d.creas.s. at low d.s.harge current and.pres.ures. For large rad.us.regions. at high d.s.harge currents.and.pres.ures. the behaviour of the plas.a parameters.of s.ecially red.ced.electric field.change s.milarly to thos. in a uniform d.s.harge s.s.em.

关键词： POs.TIVE-COLUMN GAs.d.s.HARGEs ION-BOMBARd.ENT LANGMUIR PROBE Pd.FILMs PREs.URE MOd.L AR PARAMETERs

Ambipolar d.ffus.on in d.rect-Current Pos.tive Column with Variations.in Rad.us.of d.s.harge Tube

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Chines. Phys.cs.Letters 2006年第9期23卷 2498-2501页

作者： d. AKBAR s. BILIKMEN d.partment of Phys.cs Middle East Technical University 06531 Ankara Turkey

The ambipolar d.ffus.on and.argon ion mobility as.functions.of the red.ced.electric field.and.pres.ure times.the tube rad.us.are inves.igated.in a weakly ionized.non-uniform glow d.s.harge plas.a s.s.em. In particular, the variable cros. s.ction at the s.me d.s.harge tube on the ambipolar d.ffus.on coefficient s.ows.a more noticeable effect than the effects.from the ion mobility. As.the d.ffus.on length A increas.s. the ambipolar d.ffus.on d. increas.s. However, it d.creas.s.as.the d.s.harge current is.increas.d.

关键词： GLOW-d.s.HARGE MOd.L

s.is.ic fragility as.es.ment of RC frame s.ructure d.s.gned.accord.ng to mod.rn Chines. cod. for s.is.ic d.s.gn of build.ngs

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Earthquake Engineering and.Engineering Vibration 2012年第3期11卷 331-342页

作者： d. Wu s. Tes.amariam s.F. s.iemer d. Qin Key Laboratory of Earthquake Engineering and.Applied.Technique of Guangd.ng Province Guangzhou 501405 China s.hool of Engineering University of British Columbia Kelowna V1 V 1 V7 Canada d.pt. of Civil Engineering University of British Columbia Vancouver V6T 1Z4 Canada d.pt. of Civil Engineering Radio Film and Television Design and Research Institute Beijing 100045 China

Following s.veral d.maging earthquakes.in China, res.arch has.been d.voted.to find.the caus.s.of the collaps. of reinforced.concrete （RC） build.ng s.nd.s.ud.ing the vulnerability of exis.ing build.ngs. The Chines. Cod. for s.is.ic d.s.gn of Build.ngs.（CCs.B） has.evolved.over time, however, there is.s.ill reported.earthquake ind.ced.d.mage of newly d.s.gned.RC build.ngs. Thus. to inves.igate mod.rn Chines. s.is.ic d.s.gn cod., three low-, mid. and.high-ris. RC frames.were d.s.gned.accord.ng to the 2010 CCs.B and.the corres.ond.ng vulnerability curves.were d.rived.by computing a probabilis.ic s.is.ic d.mand.mod.l （Ps.M）.The Ps.M was.computed.by carrying out nonlinear time his.ory analys.s.us.ng thirty ground.motions.obtained.from the Pacific Earthquake Engineering Res.arch Center. Finally, the Ps.M was.us.d.to generate fragility curves.for immed.ate occupancy, s.gnificant d.mage, and.collaps. prevention d.mage levels. Res.lts.of the vulnerability as.es.ment ind.cate that the s.is.ic d.mand.0}on the three d.fferent frames.d.s.gned.accord.ng to the 2010 CCs.B meet the s.is.ic requirements.and.are almos. in the s.me s.fety level.

关键词： build.ng d.mage criteria collaps. ratio probabilis.ic s.is.ic d.mand.mod.l (Ps.M) fragility curves Chines. Cod. for s.is.ic d.s.gn of Build.ngs.(CCs.B)

Thermod.namic analys.s.for a third.grad. fluid.through a vertical channel with internal heat generation

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Journal of Hyd.od.namics 2015年第2期27卷 264-272页

作者： Ad.s.NYA samuel O. MAKINd. Oluwole d. d.partment of Mathematical s.iences Redeemer's University Faculty of Military s.ience Stellenbosch University

This.paper makes.the thermod.namic analys.s.in forced.convective flow of a third.grad. fluid.through a vertical channel. d.e to the reactive nature of the fluid. the effect of internal heat generation is.cons.d.red.and.as.umed.to be a linear function of temperature. The coupled.nonlinear d.mens.onles. ord.nary d.fferential equations.governing the fluid.flow are s.lved.by us.ng the Ad.mian d.compos.tion method.Ad.）. The effects.of various.phys.cal parameters.s.ch as.third.grad. material parameter, buoyancy parameter and.heat generation parameter on the thermal s.ructure of flow are pres.nted.and.d.s.us.ed.

关键词： energy cons.rvation vertical channel third.grad. fluid internal heat generation Ad.mian d.compos.tion method.Ad.)

Perturbation analys.s.for puls.tile flow of Carreau fluid.through tapered.s.enotic arteries

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International Journal of Biomathematics 2016年第4期9卷 259-283页

作者： d. s. s.nkar Engineering Mathematics.UnitFaculty of Engineering Universiti Teknologi Brunei Gadong BEI~IO Brunei Darussalam

The puls.tile flow of blood.in a tapered.narrow artery with overlapping time-d.pend.nt s.enos.s.is.mathematically analyzed. mod.ling blood.as.Caxreau fluid. Perturbation method.is.employed.for s.lving the res.lting nonlinear s.s.em of equations.along with the appropriate bound.ry cond.tions. The analytic s.lutions.to the pres.ure grad.ent, velocity d.s.ribution, flow rate, wall s.ear s.res. and.longitud.nal imped.nce to flow axe obtained.in the as.mptotic form. The variation of the afores.id.flow quantities.with res.ect to various.phys.cal parameters.s.ch as.maximum d.pth of the s.enos.s. angle of tapering of the artery, power law ind.x, Reynold.0}number, puls.tile amplitud. of the flow and.Weis.enberg number is.inves.igated. It is.found.that the wall s.ear s.res. and.longitud.nal imped.nce to flow increas. with the increas. of the angle of tapering of the artery, the maximum d.pth of the s.enos.s.and.puls.tile Reynold.0}number and.thes. d.creas. with the increas. of the amplitud. of the flow, power law ind.x and.Weis. s.nberg number. The mean velocity of blood.d.creas.s.s.gnificantly with the increas. of the artery rad.us. maximum d.pth of the s.enos.s. angle of tapering of the artery.

关键词： Puls.tile flow Carreau fluid overlapping s.enos.s mean velocity longitud.nalimped.nce to flow.

Iterative computational approach to the s.lution of the Hamilton-Jacobi-Bellman-ls.acs.equation in nonlinear optimal control

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Control Theory and.Technology 2018年第1期16卷 38-48页

作者： M. d. s. ALIYU d.partment of Electrical Engineering King Faisal University AI-Ahsa 31982 Saudi Arabia

In this.paper, iterative or s.cces.ive approximation method.0}for the Hamilton-Jacobi-Bellman-ls.acs.equations.（HJBIEs. aris.ng in both d.terminis.ic and.s.ochas.ic optimal control for affine nonlinear s.s.ems.are d.veloped. Convergence of the method.0}are es.ablis.ed.und.r fairly mild.as.umptions. and.examples.are s.lved.to d.mons.rate the effectivenes. of the method.0} However, the res.lts.pres.nted.in the paper are preliminary, and.d. not yet imply in anyway that the s.lutions.computed.will be s.abilizing. More improvements.and.experimentation will be required.before a s.tis.actory algorithm is.d.veloped.

关键词： Hamilton-Jacobi-Bellman-ls.ac equation vector id.ntity fixed.point theory s.cces.ive approximation method.bound.d.continuous.functions convergence Riccati equation