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植物CBL基因家族的研究进展

核农学报 2015年第5期29卷 892-898页

作者：董连红史素娟 s m nuruzzaman manik 苏玉龙刘朝科冯祥国胡晓明王倩刘好宝中国农业科学院烟草研究所/农业部烟草生物学与加工重点实验室山东青岛266101 中国农业科学院研究生院北京100081 青岛农业大学山东青岛266109 川渝中烟工业公司四川成都610000

细胞中游离的Ca2+是植物细胞中普遍存在的第二信使,类钙调神经素B亚基蛋白CBL作为一种特殊的钙感受器在植物生长发育和逆境胁迫响应过程中发挥重要作用。本文主要对植物CBL家族的起源与进化、蛋白结构、亚细胞定位以及CBL的功能进行综述... 详细信息

细胞中游离的Ca2+是植物细胞中普遍存在的第二信使,类钙调神经素B亚基蛋白CBL作为一种特殊的钙感受器在植物生长发育和逆境胁迫响应过程中发挥重要作用。本文主要对植物CBL家族的起源与进化、蛋白结构、亚细胞定位以及CBL的功能进行综述,并对今后钙感受器CBL家族的研究重点和发展方向进行了展望。

关键词： Ca^2+信号 CBL CIPK 非生物逆境信号转导

林烟草蛋白激酶NsylCIPK3基因的克隆与功能分析

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植物遗传资源学报 2015年第3期16卷 633-639页

作者：董连红史素娟 s m nuruzzaman manik 苏玉龙毛静静王傚弘周开燕刘林王倩刘好宝中国农业科学院烟草研究所/农业部烟草生物学与加工重点实验室青岛266101 中国农业科学院研究生院北京100081 青岛农业大学农学与植物保护学院青岛266109 川渝中烟工业公司成都610000

CIPK蛋白激酶家族(CBL-interacting protein kinase)是一类丝氨酸/苏氨酸蛋白激酶家族,与类钙调磷酸酶B亚基CBL(calcineurin B-like protein)蛋白共同形成CBL-CIPK网络,在植物的生长发育和逆境胁迫响应过程中发挥重要作用。烟草中该家... 详细信息

CIPK蛋白激酶家族(CBL-interacting protein kinase)是一类丝氨酸/苏氨酸蛋白激酶家族,与类钙调磷酸酶B亚基CBL(calcineurin B-like protein)蛋白共同形成CBL-CIPK网络,在植物的生长发育和逆境胁迫响应过程中发挥重要作用。烟草中该家族的研究还比较少,本研究从林烟草(Nicotiana sylvestris)中获得一个CIPK家族基因,该基因与拟南芥和杨树中的CIPK3同源性分别为68.4%和87.5%,将其命名为Nsyl CIPK3。氨基酸序列分析表明,Nsyl CIPK3具有CIPK蛋白家族的典型结构特征,在N端和C端分别具有典型的激活环结构域和NAF结构域。进化树分析显示,Nsyl CIPK3属于CIPK蛋白亚家族Ⅱ。表达模式研究表明,该基因在林烟草的叶和腋芽中的表达量相对较高,在主根中的表达量次之,在侧根、茎、花瓣和萼片中的表达量相对较低,并且在烟草成熟期的叶中表达量明显升高。在高盐、紫外光和低钾胁迫下该基因的表达发生不同程度的上调。酵母双杂交结果显示,Nsyl CIPK3可与Nsyl CBL9互作。推测Nsyl CIPK3可能通过与Nsyl CBL9互作形成信号通路,激活下游靶蛋白,参与烟草响应非生物逆境胁迫的信号转导过程。

关键词：林烟草 CIPK3 非生物逆境信号转导蛋白互作

Predicting maximum Lifespan Limits at mean menopausal Age

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Journal of mathematical Research with Applications 2025年第1期 133-142页

作者： m.sUmATHI s.ANTONY CARLA Department of mathematics N.M.S.S.Vellaichamy Nadar College Research scholar (Part-time) Madurai Kamaraj University

The age at which a woman enters natural menopause has also been associated to death from any cause. menopause is a natural component of aging that happens between the ages of 45 and 55, with the average menopausal age being 51. Previous research has revealed the age at which women reach menopause, but there is no evidence to support the link between menopause and longevity. We made a study in assessing the limits of maximum lifespan at menopausal age in our previous article. In this paper, we aim to predict the maximum lifespan of women at mean menopausal age.

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Impact of Zika virus non-structural protein mutations on hippocampal damage

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Neural Regeneration Research 2025年第8期20卷 2307-2308页

作者： Larissa m.G.Cassiano Roney s.Coimbra Neurogenômica/Imunopatologia Instituto RenéRachouFiocruzBelo HorizonteBrazil Departamento de Bioquímica e Imunologia Instituto de Ciências BiológicasUniversidade Federal de Minas GeraisBelo HorizonteBrazil

The Zika virus(ZIKV),a member of the Flaviviridae family,attracted worldwide attention for its connection to severe neurological effects,notably microcephaly in newborns,first reported during the 2015 epidemic in ***,its impact goes beyond fetal and neonatal abnormalities,also affecting the central nervous system(CNs)in both children and adults,leading to enduring cognitive and behavioral impairments.

关键词： damage fetal neonatal

Effect of COOH-functionalized sWCNT addition on the electrical and photovoltaic characteristics of malachite Green dye based photovoltaic cells

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Journal of semiconductors 2014年第12期35卷 32-37页

作者： s.Chakraborty N.B.manik Condensed matter Physics Research Center Department of Physics Jadavpur University

We report the effect of COOH-functionalized single walled carbon nanotubes（COOH-sWCNT） on the electrical and photovoltaic characteristics of malachite Green（mG） dye based photovoltaic cells. Two different types of photovoltaic cells were prepared, one with mG dye and another by incorporating COOH-sWCNT with this dye. Cells were characterized through different electrical and photovoltaic measurements including photocurrent measurements with pulsed radiation. From the dark current–voltage（I–V） characteristic results, we observed a certain transition voltage（Vth/ for both the cells beyond which the conduction mechanism of the cells change sharply. For the mG dye, Vthis 3.9 V whereas for COOH-sWCNT mixed with this dye, Vthdrops to 2.7 V. The device performance improves due to the incorporation of COOH-sWCNT. The open circuit voltage and short circuit current density change from 4.2 to 97 m V and from 108 to 965 A/cm2 respectively. Observations from photocurrent measurements show that the rate of growth and decay of the photocurrent are quite faster in the presence of COOH-sWCNT. This observation indicates a faster charge separation processes due to the incorporation of COOHsWCNT in the mG dye cells. The high aspect ratio of COOH-sWCNT allows efficient conduction pathways for the generated charge carriers.

关键词： mG dye COOH-sWCNT photovoltaic devices charge transport

Brain-derived neurotrophic factor signaling in the neuromuscular junction during developmental axonal competition and synapse elimination

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Neural Regeneration Research 2025年第2期20卷 394-401页

作者： Josep Tomàs Víctor Cilleros-mañé Laia Just-Borràs marta Balanyà-segura Aleksandra Polishchuk Laura Nadal marta Tomàs Carolina silvera-simón manel m.santafé maria A.Lanuza Unitat d’Histologia i Neurobiologia(UHNeurob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

During the development of the nervous system,there is an overproduction of neurons and *** competition between neighboring nerve endings and synapses performing different activity levels leads to their elimination or *** have extensively studied the involvement of the brain-derived neurotrophic factor-Tropomyosin-related kinase B receptor neurotrophic retrograde pathway,at the neuromuscular junction,in the axonal development and synapse elimination process versus the synapse *** purpose of this review is to describe the neurotrophic influence on developmental synapse elimination,in relation to other molecular pathways that we and others have found to regulate this *** particular,we summarize our published results based on transmitter release analysis and axonal counts to show the different involvement of the presynaptic acetylcholine muscarinic autoreceptors,coupled to downstream serine-threonine protein kinases A and C(PKA and PKC)and voltage-gated calcium channels,at different nerve endings in developmental *** dynamic changes that occur simultaneously in several nerve terminals and synapses converge across a postsynaptic site,influence each other,and require careful studies to individualize the mechanisms of specific *** describe an activity-dependent balance(related to the extent of transmitter release)between the presynaptic muscarinic subtypes and the neurotrophin-mediated TrkB/p75NTR pathways that can influence the timing and fate of the competitive interactions between the different axon *** downstream displacement of the PKA/PKC activity ratio to lower values,both in competing nerve terminals and at postsynaptic sites,plays a relevant role in controlling the elimination of supernumerary ***,calcium entry through L-and P/Q-subtypes of voltage-gated calcium channels(both channels are present,together with the N-type channel in developing nerve terminals)contributes to red

关键词： acetylcholine release adenosine receptors axonal competition brain-derived neurotrophic factor calcium channels motor end-plate muscarinic acetylcholine receptors postnatal synapse elimination serine kinases tropomyosin-related kinase receptorB

Emerging role of A-kinase anchoring protein 5 signaling in reward circuit function

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Neural Regeneration Research 2025年第10期20卷 2913-2914页

作者： William J.Flerlage mark L.Dell’Acqua Brian m.Cox Fereshteh s.Nugent Uniformed services University of the Health sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Department of Pharmacology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(simmons et al.,2024).Diverse sets of distinct molecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through complex interactions organized by numerous multivalent protein scaffolds,including the family of proteins known as A-kinase anchoring proteins(AKAPs).

关键词： function supporting

solution‑Processed Thin Film Transparent Photovoltaics:Present Challenges and Future Development

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Nano-micro Letters 2025年第2期17卷 566-600页

作者： Tianle Liu munerah m.s.Almutairi Jie ma Aisling stewart Zhaohui Xing mengxia Liu Bo Hou Yuljae Cho Um-sJTU Joint Institute Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China school of Physics and Astronomy Cardiff UniversityCardiff CF243AAWalesUK Department of Electrical and Computer Engineering Yale UniversityNew HavenCT 06511USA Energy sciences Institute Yale UniversityWest HavenCT 06516USA Future Photovoltaics Research Center Global Institute of Future TechnologyShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Electrical energy is essential for modern society to sustain economic *** soaring demand for the electrical energy,together with an awareness of the environmental impact of fossil fuels,has been driving a shift towards the utilization of solar ***,traditional solar energy solutions often require extensive spaces for a panel installation,limiting their practicality in a dense urban *** overcome the spatial constraint,researchers have developed transparent photovoltaics(TPV),enabling windows and facades in vehicles and buildings to generate electric *** TPV advancements are focused on improving both transparency and power output to rival commercially available silicon solar *** this review,we first briefly introduce wavelength-and non-wavelengthselective strategies to achieve *** of merit and theoretical limits of TPVs are discussed to comprehensively understand the status of current TPV *** we highlight recent progress in different types of TPVs,with a particular focus on solution-processed thin-film photovoltaics(PVs),including colloidal quantum dot PVs,metal halide perovskite PVs and organic *** applications of TPVs are also reviewed,with emphasis on agrivoltaics,smart windows and ***,current challenges and future opportunities in TPV research are pointed out.

关键词： Transparent semiconductors solution-processable transparent solar cell Emerging solar cell materials Buildingintegrated photovoltaics

Unsupervised method of clustering and labeling of the online product based on reviews

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International Journal of modeling, simulation, and scientific Computing 2021年第2期12卷 175-197页

作者： md masum Billah mohammad nuruzzaman Bhuiyan md.Akterujjaman Computer science American International University Bangladesh(AIUB)Dhaka-1229 Bangladesh Institute of Information Technology Noakhali science and Technology University Noakhali-3814 Bangladesh software Engineering Daffodil International UniversityDhaka-1207Bangladesh

This paper presents an unsupervised approach to cluster reviews of products collected from Amazon and then generates its labels of each *** of using a complete review,this paper splits a review into sentences and considers all sentences from the reviews as inputs for *** Agglomerative Clustering(HAC)is used to cluster *** approaches of cluster labeling are also *** labeling,three different methods have been used to find a limited number of essential words for each *** essential words are used to construct *** phrases are used as labels for each *** paper compares the result of the labeling method with baseline *** the result evaluation,all the labeling methods outperform the baseline *** aim of this research is cluster labeling that makes a set of labels to describe a cluster content and distinguishes the labels from other cluster labels.

关键词： Cluster labeling construct phrases baseline method sentence clustering