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chinese Optics letters 2003年第1期1卷 56-59页

作者： W.liu Q.luo s.l.chin Department de physique de genie physique et d'optique and Centre d'optiquephotonique et laser (COPL) Universite Laval Quebec (Quebec) Canada G1K 7P4Department de physique de genie physique et d'optique and Centre d'optiquephotonique et laser (COPL) Universite Laval Quebec (Quebec) Canada G1K 7P4Department de physique de genie physique et d'optique and Centre d'optiquephotonique et laser (COPL) Universite Laval Quebec (Quebec) Canada G1K 7P4

In this work we present experiments by focusing 42 femtosecond laser pulses in air using three differentfocal length lenses: f=100, 30 and 5 cm. For the longest focal length, only the filament, which is aweak plasma column,is observed. When the shorter focal length lens is used, a high density plasma isgenerated near the geometrical focus and coexists with a weak plasma channel of the filamemt. Under thetightest focusing condition, filamentation is prevented and only a strong plasma volume appears at tehgeometrical focus.

关键词： in as it be is Competition between multiphoton/tunnel ionization and filamentation induced by powerful femtosecond laser pulses in air by line

Focusing limits of intense ultrafast laser pulses in a high pressure gas: road to new spectroscopic source

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Focusing limits of intense ultrafast laser pulses in a high ...

Effect of beam diameter on the propagation of intense femtosecond laser pulses

CCAsT“2002年全国强场激光物理”研讨会

作者： A.Talebpour M.Abdel-Fattah s.l.chin Centre’ Optique Photonique et Laser （COPL） and Dept de Physique Universit Laual Qubec Qc. Canada GIK 7P4 Centre’ Optique Photonique et Laser （COPL） and Dept de Physique Universit Laual Qubec Qc. Canada GIK 7P4 Centre’ Optique Photonique et Laser （COPL） and Dept de Physique Universit Laual Qubec Qc. Canada GIK 7P4

＜正＞ As a result of focusing ultrafast Ti:sapphire laser pulses in a gas. a plasma column is created. Its density does not exceed some limiting value as a result of the defocusing by the electrons resulting from muluphoton ionization and the involvement of high order nonlinearities. The spectrum of the radiation from the excited species in the column has little contribution from the plasma continuum and the line broadening is less than that of the spectra radiated from a plasma generated by a long laser pulse. Thus. the spectroscopic source obtained using short laser pulses is an excellent source for spectroscopy, （?）2000 Published by Elsevier science B.V.

关键词： Propagation: Ti:sapphire laser pulse Plasma: spectroscopy Photo-emission spectrum

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Effect of beam diameter on the propagation of intense femtos...

Femtosecond laser pulse filamentation sustained by a background field reservoir

2004年全国强场激光物理会议

作者： s．A．Hosseini J．-F．Gravel O．G．Kosareva N.A.Panov N Akzbck V．P．Kandidov G．Roy s．l．chin Centre d’Optique Photonique et Laser（COPL）and Département de Physiquede Génie Physique et d’OptiqueUniversité LavalQuébecQCG1K 7P4 Canada Centre d’Optique Photonique et Laser（COPL）and Département de Physiquede Génie Physique et d’OptiqueUniversité LavalQuébecQCG1K 7P4 Canada International laser Center Physics DepartmentM.V.Lomonosov Moscow State UniversityMoscow119992Russia International laser Center Physics DepartmentM.V.Lomonosov Moscow State UniversityMoscow119992Russia Time Domain Corporation 7057 Old Madison PikeHuntsvilleAlabama 35806USA International laser Center Physics DepartmentM.V.Lomonosov Moscow State UniversityMoscow119992Russia The remote sensing group of the Defense Research and development Center-Valcartier（DRDC-Valcartier） Val-BelairQCG3J 1X5Canada Centre d’Optique Photonique et Laser（COPL）and Département de Physiquede Génie Physique et d’OptiqueUniversité LavalQuébecQCG1K 7P4 Canada

＜正＞Propagation of intense fs pulses and the generation of multiple filaments Theoretical consideration The role of the relative positioning of the initial perturbations Experiments large size beam small size beam C...

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Femtosecond laser pulse filamentation sustained by a backgro...

Emerging role of A-kinase anchoring protein 5 signaling in reward circuit function

2004年全国强场激光物理会议

作者： s l chin s Hoseinni B Ferland F Theberge J-F Gravel O Kosareva V P Kandidov N Akozbek C．M．Bowden A Becket R．sauerbrey H schroeder Center for Optics Photonics and Laser（COPL）＆ Dept of PhysicsEngineering Physics and OpticsLaval UniversityQuebec CityCanada Center for Optics Photonics and Laser ＆ Dept of PhysicsEngineering Physics and OpticsLaval UniversityQuebec CityCanada Center for Optics Photonics and Laser ＆ Dept of PhysicsEngineering Physics and OpticsLaval UniversityQuebec CityCanada Center for Optics Photonics and Laser ＆ Dept of PhysicsEngineering Physics and OpticsLaval UniversityQuebec CityCanada Center for Optics Photonics and Laser ＆ Dept of PhysicsEngineering Physics and OpticsLaval UniversityQuebec CityCanada International laser Center Department of PHysicsMoscow State UniversityMOSCOWRussia International laser Center Department of PHysicsMoscow State UniversityMOSCOWRussia Us AMCOM ＆ Timedomain Corp． HuntsvilleAlabamaUSA Us AMCOM ＆ Timedomain Corp． HuntsvilleAlabamaUSA Max-Planck Institute for the Physics of Complex system DresdenGermany（EU） Friedrich-schiller University of Jena Germany（EU） Max-Planck-Institute for Quantum Optics GarchingGermany（EU）

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Neural Regeneration Research 2025年第10期20卷 2913-2914页

作者： William J.Flerlage Mark l.Dell’Acqua Brian M.Cox Fereshteh s.Nugent Uniformed services University of the Health sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Department of Pharmacology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(simmons et al.,2024).Diverse sets of distinct molecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through complex interactions organized by numerous multivalent protein scaffolds,including the family of proteins known as A-kinase anchoring proteins(AKAPs).

关键词： function supporting

Getting physical with medical education:Exercise based virtual anatomy review classes for medical students

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World Journal of Methodology 2025年第1期15卷 20-25页

作者： Nadeesha R samarasinghe Taniya s Nagpal Michele l Barbeau Charys M Martin Division of General surgery Faculty of MedicineUniversity of British ColumbiaVancouver V6T 1Z3BCCanada Faculty of Kinesiology Sport and RecreationUniversity of AlbertaEdmonton T6G 2R3ABCanada Anatomy and Cell Biology University of Western OntarioLondon N6A 3K7ONCanada Department of Anatomy and Cell Biology Schulich School of Medicine and DentistryThe University of Western OntarioLondon N6A 3K7ONCanada

The benefits of regular physical activity are well ***,few studies have examined the effectiveness of integrating physical activity(PA)into curricula within a post-secondary *** investigate the incorporation of PA into medical curriculum,we developed a series of optional exercise-based review sessions designed to reinforce musculoskeletal(MsK)anatomy course *** synchronous sessions were co-taught by a group fitness instructor and an anatomy *** fitness instructor would lead students through both strength and yoga style exercises,while the anatomy instructor asked questions about relevant anatomical structures related to course material previously *** the sessions,participants were asked to evaluate the classes on their self-reported exam preparedness in improving MsK anatomy knowledge,PA levels,and mental *** participants completed surveys;a majority agreed that the classes increased understanding of MsK concepts(90.0%)and activity levels(97.7%).Many(70.0%)felt that the classes helped reduce *** majority of respondents(90.0%)agreed that the classes contributed to increased feelings of social ***,medical students saw benefit in PA based interventions to supplement MsK course *** with increasing activity levels and promoting health behaviours,integrating PA into medical curriculum may improve comprehension of learning material,alleviate stress and foster social connectivity among medical students.

关键词： Medical education Musculoskeletal Anatomy Exercise Online learning

Thermal stress relaxation in shot peened and laser peened nickel-based superalloy

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Journal of Materials science & Technology 2020年第24期59卷 100-106页

作者： K.s.chin s.Idapalapati D.T.Ardi school of Mechanical and Aerospace Engineering Nanyang Technological University50 Nanyang AvenueSingapore 639798Singapore Advanced Remanufacturing and Technology Centre 3 CleanTech LoopCleanTech Two#01/01Singapore 637143Singapore

The effects of cold work produced by peening processes in residual stress relaxation under elevated temperatures were *** types of peening processes namely shot peening and laser peening were used to generate different amount of cold work and residual stresses in the *** of residual stress induced by cold working were carried out using X-ray diffraction coupled with electrochemical polishing method to measure the variation of residual stress with *** stresses in shot peened samples were observed to relax more rapidly than that of laser peened ones when subjected to thermal *** data collected from the experimental investigation was then used to build a correlation function to model the effects of cold work on residual stress relaxation.A parameter describing cold work’s contribution to stress relaxation is introduced into the well-known Zener-WertAvrami(ZWA)*** model was validated against experimental measurements and showed good agreement in both shot peened and laser peened samples.

关键词： Residual stress Cold work surface treatment Nickel-based superalloys

Beginning from the end:the presynaptic terminal as a pathomechanism hub in frontotemporal dementia and amyotrophic lateral sclerosis

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Neural Regeneration Research 2025年第11期20卷 3217-3218页

作者： laura Huggon Emma l.Clayton UK Dementia Research Institute at King’s College london LondonUK Department of Basic and Clinical Neuroscience Institute of Psychiatry Psychology&NeuroscienceKing’s College LondonLondonUK

Frontotemporal dementia and amyotrophic lateral sclerosis:Frontotemporal dementia(F T D)and amyo t rophic lateral sclerosis(Als)are neurodegenerative diseases with significant overlapping *** these neurodegenerative diseases affect different neuronal populations(with FTD affecting neurons of the frontal and temporal lobes,and Als affecting upper and lower motor neurons),these two diseases are complexly *** and Als exist on a disease spectrum,with shared genetic causes,clinical presentations,and pathologies.

关键词： diseases amyotrophic sclerosis

Polyethylene glycol has immunoprotective effects on sciatic allografts, but behavioral recovery and graft tolerance require neurorrhaphy and axonal fusion

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Neural Regeneration Research 2025年第4期20卷 1192-1206页

作者： Tyler A.smith liwen Zhou Cameron l.Ghergherehchi Michelle Mikesh Cathy Z.Yang Haley O.Tucker JuliAnne Allgood Jared s.Bushman George D.Bittner Department of Molecular Biosciences University of Texas at AustinAustinTXUSA Department of Neuroscience University of Texas at AustinAustinTXUSA Division of Pharmaceutical sciences University of WyomingLaramieWYUSA

Behavioral recovery using(viable)peripheral nerve allografts to repair ablation-type(segmental-loss)peripheral nerve injuries is delayed or poor due to slow and inaccurate axonal ***,such peripheral nerve allografts undergo immunological rejection by the host immune *** contrast,peripheral nerve injuries repaired by polyethylene glycol fusion of peripheral nerve allografts exhibit excellent behavioral recovery within weeks,reduced immune responses,and many axons do not undergo Wallerian *** relative contribution of neurorrhaphy and polyethylene glycol-fusion of axons versus the effects of polyethylene glycol per se was unknown prior to this *** hypothesized that polyethylene glycol might have some immune-protective effects,but polyethylene glycol-fusion was necessary to prevent Wallerian degeneration and functional/behavioral *** examined how polyethylene glycol solutions per se affect functional and behavioral recovery and peripheral nerve allograft morphological and immunological responses in the absence of polyethylene glycol-induced axonal ***-type sciatic nerve injuries in outbred sprague–Dawley rats were repaired according to a modified protocol using the same solutions as polyethylene glycol-fused peripheral nerve allografts,but peripheral nerve allografts were loose-sutured(loose-sutured polyethylene glycol)with an intentional gap of 1–2 mm to prevent fusion by polyethylene glycol of peripheral nerve allograft axons with host *** to negative control peripheral nerve allografts not treated by polyethylene glycol and in contrast to polyethylene glycol-fused peripheral nerve allografts,animals with loose-sutured polyethylene glycol peripheral nerve allografts exhibited Wallerian degeneration for all axons and myelin degeneration by 7 days postoperatively and did not recover sciatic-mediated behavioral functions by 42 days *** morphological signs of rejection,such as col

关键词： allograft rejection axotomy macrophage myelin nerve repair polyethylene glycol(PEG) sciatic nerve T cell transplantation Wallerian degeneration

sequence assembly using next generation sequencing data —challenges and solutions

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science china(life sciences) 2014年第11期57卷 1140-1148页

作者： chin Francis Y.l. lEUNG Henry C.M. YIU s.M. Department of Computer science The University of Hong Kong

sequence assembling is an important step for bioinformatics *** the help of next generation sequencing(NGs)technology,high throughput DNA fragment(reads)can be randomly sampled from DNA or RNA molecular ***,as the positions of reads being sampled are unknown,assembling process is required for combining overlapped reads to reconstruct the original DNA or RNA *** with traditional sanger sequencing methods,although the throughput of NGs reads increases,the read length is shorter and the error rate is *** introduces several problems in ***,paired-end reads instead of single-end reads can be sampled which contain more *** existing assemblers cannot fully utilize this information and fails to assemble longer *** this article,we will revisit the major problems of assembling NGs reads on genomic,transcriptomic,metagenomic and metatranscriptomic *** will also describe our IDBA package for solving these *** package has adopted several novel ideas in assembling,including using multiple k,local assembling and progressive depth *** with existence assemblers,IDBA has better performance on many simulated and real sequencing datasets.

关键词： genomic assembling de Bruijn graph paired-end reads next generation sequencing