检索结果-南通市图书馆

Modulation of Tropical Cyclogenesis in the Western North Pacific by the Quasi-Biweekly Oscillation

Advances in Atmospheric Sciences 2016年第12期33卷 1361-1375页

作者： Haikun ZHAO Chunzai WANG Ryuji YOSHIDA Key Laboratory of Meteorological Disaster Ministry of Education/Joint International Research Laboratory of Climate and Environment Change/Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disaster/Pacific Typhoon Research Center/Earth System Modeling CenterNanjing University of Information Science and TechnologyNanjing 210044China NOAA/Atlantic Oceanographic and Meteorological Laboratory MiamiFL33149USA RIKEN Advanced Institute for Computational Science Kobe650-0047Japan

The quasi-biweekly oscillation （QBWO） is the second most dominant intraseasonal mode over the westem North Pacific （WNP） during boreal summer. In this study, the modulation of WNP tropical cyclogenesis （TCG） by the QBWO and its association with large-scale patterns are investigated. A strong modulation of WNP TCG events by the QBWO is found. More TCG events occur during the QBWO＇s convectively active phase. Based on the genesis potential index （GPI）, we further evaluate the role of environmental factors in affecting WNP TCG. The positive GPI anomalies associated with the QBWO correspond well with TCG counts and locations. A large positive GPI anomaly is spatially correlated with WNP TCG events during a life cycle of the QBWO. The low-level relative vorticity and mid-level relative humidity appear to be two dominant contributors to the QBWO-composited GPI anomalies during the QBWO＇s active phase, followed by the nonlinear and potential intensity terms. These positive contributions to the GPI anomalies are partly offset by the negative contribution from the vertical wind shear. During the QBWO＇s inactive phase, the mid-level relative humidity appears to be the largest contributor, while weak contributions are also made by the nonlinear and low-level relative vorticity terms. Meanwhile, these positive contributions are partly cancelled out by the negative contribution from the potential intensity. The contributions of these environmental factors to the GPI anomalies associated with the QBWO are similar in all five flow patterns--the monsoon shear line, monsoon confluence region, monsoon gyre, easterly wave, and Rossby wave energy dispersion associated with a preexisting TC. Further analyses show that the QBWO strongly modulates the synoptic-scale wave trains （SSWs） over the WNP, with larger amplitude SSWs during the QBWO＇s active phase. This implies a possible enhanced （weakened） relationship between TCG and SSWs during the active （inactive） phase. This study improves our understanding of the modulation of WNP TCG b

关键词： tropical cyclogenesis quasi-biweekly oscillation genesis potential index large-scale patterns western NorthPacific

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Investigation into the biological functions of Hepatocyte Nuclear Factor-1beta in the clear cell adenocarcinoma of ovary

Investigation into the biological functions of Hepatocyte Nu...

引用

The First Asian Conference on Endometriosis(ACEⅠ)

作者： Hiroshi Shigetomi Yoriko Yoshizawa Yoshihiko Yamada ryuji Kawaguchi Shozo yoshida Naoto Furukawa Hidekazu Oi Hiroshi Kobayashi Department of Obstetrics and Gynecology Nara Medical University Keij Shimada Department of Pathology Nara Medical University Seiji Kanayama Department of Obstetrics and Gynecology Hyogo Cancer Center

＜正＞Objectives Ovarian cancer,especially endometrioid adenocarcinoma and clear cell adenocarcinoma,is frequently accompanied with ovarian chocolate cysts.So it is considered that ovarian chocolate cysts may be the pathological basis of these ovarian cancers.The genetic abnormalities of PTEN and p53have been reported to participate in the development of ovarian

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Evaluation of the <i>BRCA</i>1/2 mutation as a prognostic marker in primary peritoneal serous cancer

引用

Open Journal of Obstetrics and Gynecology 2013年第9期3卷 653-657页

作者： Naoto Furukawa Sumire Ohno Takahiko Kasai Sachiko Morioka Fuminori Ito Yasuhito Tanase Shoji Haruta Seiji Kanayama ryuji Kawaguchi Shozo yoshida Hiroshi Kobayashi Department of Obstetrics and Gynecology Nara Medical University Kashihara Japan Diagnostic Pathology Nara Medical University Kashihara Japan

Introduction: The present study was a retrospective investigation of the relation between immunohistochemical BRCA1/2 status and prognosis in patients with primary peritoneal serous cancer (PPSC). Materials and Methods: We retrospectively evaluated 14 consecutive patients diagnosed with PPSC other than hereditary breast and ovarian cancer between 2005 and 2010. All patients had serum CA125 levels >40 U/mL prior to starting first-line chemotherapy with paclitaxel and carboplatin. Paclitaxel was administered as a 3-hour intravenous infusion at a dose of 175 mg/m2 on day 1, and carboplatin was delivered at an area under the curve of 5 based on the Calvert method. Patients received six cycles of first-line chemotherapy, except patients whose disease was determined to be progressive during the chemotherapy regimen. BRCA1/2 and p53 protein expression was determined by immunohistochemistry of patient tissue samples. The Cox proportional hazards model was used to evaluate univariate and independent multivariate associations with the effect of clinical parameters, such as age at diagnosis;tumor histology;tumor grade;and rate of change in CA125, and BRCA1/2, p53 status on overall survival. Probability values of less than 0.05 were considered to indicate statistical significance. Results: Two cases (14%) had the BRCA1 mutation, and none had the BRCA2 mutation. Eleven cases (79%) were positive for p53. In the univariate analysis, factors significantly associated with overall survival were (pre-chemotherapy CA125-pre-2nd chemotherapy CA125)/pre-chemotherapy CA125 (p = 0.0034) and (pre-chemotherapy CA125-pre-3rd chemotherapy CA125)/pre-chemotherapy CA125 (p = 0.0245). BRCA1 and p53 status were not predictors of overall survival. Multivariate analysis performed with overall survival as an endpoint revealed that none of the factors examined was significant. Median survival rate of patients without a BRCA1 mutation was 23.5 months (2 - 82 months), and all died. By contrast, one patient with a BRCA1 mutation remains alive at 85 mo

关键词： BRCA1 Primary Peritoneal Serous Cancer Prognosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses

引用

Cancer Communications 2024年第2期44卷 287-293页

作者： Kouya Shiraishi Atsushi Takahashi Yukihide Momozawa Yataro Daigo Syuzo Kaneko Takahisa Kawaguchi Hideo Kunitoh Shingo Matsumoto Hidehito Horinouchi Akiteru Goto Takayuki Honda Kimihiro Shimizu Masahiro Torasawa Daisuke Takayanagi Motonobu Saito Akira Saito Yuichiro Ohe Shun-ichi Watanabe Koichi Goto Masahiro Tsuboi Katsuya Tsuchihara Sadaaki Takata Tomomi Aoi Atsushi Takano Masashi Kobayashi Yohei Miyagi Kazumi Tanaka Hiroyuki Suzuki Daichi Maeda Takumi Yamaura Maiko Matsuda Yoko Shimada Takaaki Mizuno Hiromi Sakamoto Teruhiko yoshida Yasushi Goto Tatsuya yoshida Taiki Yamaji Makoto Sonobe Shinichi Toyooka Kazue Yoneda Katsuhiro Masago Fumihiro Tanaka Megumi Hara Nobuo Fuse Satoshi S.Nishizuka Noriko Motoi Norie Sawada Yuichiro Nishida Kazuki Kumada Kenji Takeuchi Kozo Tanno Yasushi Yatabe Kuniko Sunami Tomoyuki Hishida Yasunari Miyazaki Hidemi Ito Mitsuhiro Amemiya Hirohiko Totsuka Haruhiko Nakayama Tomoyuki Yokose Kazuyoshi Ishigaki Toshiteru Nagashima Yoichi Ohtaki Kazuhiro Imai Ken Takasawa Yoshihiro Minamiya Kazuma Kobayashi Kenichi Okubo Kenji Wakai Atsushi Shimizu Masayuki Yamamoto Motoki Iwasaki Koichi Matsuda Johji Inazawa Yuichi Shiraishi Hiroyoshi Nishikawa Yoshinori Murakami Michiaki Kubo Fumihiko Matsuda Yoichiro Kamatani ryuji Hamamoto Keitaro Matsuo Takashi Kohno Division of Genome Biology National Cancer Center Research InstituteTokyoJapan Department of Clinical Genomics National Cancer Center Research InstituteTokyoJapan Laboratory for Statistical Analysis Center for Integrative Medical SciencesRIKENYokohamaJapan Department of Genomic Medicine Research InstituteNational Cerebral and Cardiovascular CenterOsakaJapan Laboratory for Genotyping Development Center for Integrative Medical SciencesRIKENYokohamaJapan Center for Antibody and Vaccine Therapy Research HospitalInstitute of Medical ScienceThe University of TokyoTokyoJapan Department of Medical Oncology and Cancer Center and Center for Advanced Medicine against CancerShiga University of Medical ScienceOtsuJapan Division of Medical AI Research and Development National Cancer Center Research InstituteTokyoJapan Center for Genomic Medicine Graduate School of MedicineKyoto UniversityKyotoJapan Department of Medical Oncology Japanese Red Cross Medical CenterTokyoJapan Department of Thoracic Oncology National Cancer Center Hospital EastJapan Department of Thoracic Oncology National Cancer Center HospitalTokyoJapan Department of Cellular and Organ Pathology Graduate School of MedicineAkita UniversityAkitaJapan Department of Respiratory Medicine Tokyo Medical and Dental UniversityBunkyo-kuTokyoJapan Division of General Thoracic Surgery Department of SurgeryShinshu University School of MedicineMatsumotoNaganoJapan Department of General Surgical Science Division of General Thoracic SurgeryGunma University Graduate School of MedicineIntegrative Center of General SurgeryGunma University HospitalGunmaJapan Department of Gastrointestinal Tract Surgery Fukushima Medical University School of MedicineFukushimaJapan StaGen Co. LtdTokyoJapan Division of Thoracic Surgery National Cancer Center HospitalTokyoJapan Department of Thoracic Surgery National Cancer Center Hospital EastChibaJapan Division of Translational Informatics Exploratory Oncology Research and Clinical Trial Center(EPOC

Dear editor,Lung carcinoma is responsible for the highest fatal-ity rate among cancer-related deaths globally,with lung adenocarcinoma(LADC)emerging as the prevailing sub-type.

关键词： adenocarcinoma lung Lung

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：