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Comparison of effects of six main gastrectomy procedures on patients’ quality of life assessed by Postgastrectomy Syndrome Assessment Scale-45

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World Journal of Gastrointestinal Surgery 2021年第5期13卷 461-475页

作者： Koji Nakada Yoshiyuki Kawashima Shinichi Kinami ryoji Fukushima Hiroshi Yabusaki Akiyoshi Seshimo Naoki Hiki Keisuke Koeda Mikihiro Kano Yoshikazu Uenosono Atsushi Oshio Yasuhiro Kodera Department of Laboratory Medicine The Jikei University School of MedicineTokyo 105-8461Japan Department of Gastroenterological Surgery Saitama Cancer CenterSaitama 362-0806Japan Department of Surgical Oncology Kanazawa Medical UniversityKahoku-gun 920-0293IshikawaJapan Department of Surgery Teikyo University School of MedicineTokyo 173-8605Japan Department of Surgery Niigata Cancer Center HospitalNiigata 951-8566Japan Department of Gastrointestinal and Pediatric Surgery Tokyo Medical UniversityTokyo 160-0023Japan Department of Upper Gastrointestinal Surgery Kitasato University School of MedicineKanagawa 252-0374Japan Department of Medical Safety Science Iwate Medical UniversityIwate 028-3695Japan Department of Surgery Hiroshima City Asa Citizens HospitalHiroshima 731-0293Japan Department of Digestive Surgery Imamura General HospitalKagoshima 890-0064Japan Faculty of Letters Arts and SciencesWaseda UniversityTokyo 162-8644Japan Department of Gastroenterological Surgery Nagoya University Graduate School of MedicineNagoya 466-8550Japan

BACKGROUND The effects of various gastrectomy procedures on the patient’s quality of life(QOL)are not well ***,this nationwide multi-institutional crosssectional study using the Postgastrectomy Syndrome Assessment Scale-45(PGSAS-45),a well-established questionnaire designed to clarify the severity and characteristics of the postgastrectomy syndrome,was *** To compare the effects of six main gastrectomy procedures on the postoperative *** Eligible questionnaires retrieved from 2368 patients who underwent either of six gastrectomy procedures[total gastrectomy with Roux-en-Y reconstruction(TGRY;n=393),proximal gastrectomy(PG;n=193),distal gastrectomy with Roux-en-Y reconstruction(DGRY;n=475),distal gastrectomy with Billroth-I reconstruction(DGBI;n=909),pylorus-preserving gastrectomy(PPG;n=313),and local resection of the stomach(LR;n=85)]were *** the 19 main outcome measures of PGSAS-45,the severity and characteristics of postgastrectomy syndrome were compared for the aforementioned six gastrectomy procedures using analysis of *** TGRY and PG significantly impaired the QOL of postoperative *** QOL was excellent in LR(cardia and pylorus were preserved with minimal resection).In procedures removing the distal stomach,diarrhea subscale(SS)and dumping SS were less frequent in PPG than in DGBI and ***,there was no difference in the postoperative QOL between DGBI and *** most noticeable adverse effects caused by gastrectomy were mealrelated distress SS,dissatisfaction at the meal,and weight loss,with significant differences among the surgical *** Postoperative QOL greatly differed among six gastrectomy *** severity and characteristics of postgastrectomy syndrome should be considered to select gastrectomy procedures,overcome surgical shortcomings,and enhance postoperative care.

关键词： Gastrectomy Quality of life Postgastrectomy syndromes Patient reported outcome measures

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RAYLEIGH WAVE VELOCITY FOR FROST SUSCEPTIBLE VOLCANIC ASH DEPOSITS IN ASAMA VOLCANO

RAYLEIGH WAVE VELOCITY FOR FROST SUSCEPTIBLE VOLCANIC ASH DE...

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岩石力学与环境岩土工程国际会议

作者： ryoji Sakurada Hideo Miyaguchi Ichiro Kuroshima Akita National College of Technology Akita 011 Japan Civil Engineers Co. Ltd.Tokyo 110 Japan Mitsui Construction Co. Ltd.Tokyo 110 Japan

＜正＞In the regions covered with pyroclastic fall deposits,most of the frost-heave damages of road relates to hydrogeological conditions of a *** this study,emphasis is given to the effect of soil stratification on the frost damages of *** a geological exploration Rayleigh wave method was employed for the ashy deposits in the foot of Asama *** frost damages attributed to geological conditions can be summarized as following two forms:（1）Frost damages dominated by the thickly covered,high-heaving soils,（2）Frost damages dominated by drainage conditions of roadbed formed by low-heaving *** low-heaving soils easily become mid-heaving soils if once groundwater flows into the soils.

关键词： Rayleigh wave method frost heave volcanic ash

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Numerical Simulation of New Friction Welded Joints

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Journal of Mechanics Engineering and Automation 2013年第10期3卷 595-601页

作者： Takeshi Higashi ryoji Tsujino Kiyoshi Matsuura Yoshiaki Ueda Manabu Iguchi Faculty of Engineering Setsunan University Neyagawa 672-8508 Japan Faculty of Science and Engineering Setsunan University Neyagawa 672-8508 Japan Taiyu Corp. Neyagawa 572-0077 Japan Division of Materials Science and Engineering Graduate School of Engineering Hokkaido University Hokkaido 060-8628 Japan Faculty of Engineering Osaka Electro-Communication University Neyagawa 572-8530 Japan

In developing the new friction welding technology, the thermal elastic-plastic stress analysis by the finite element method was carried out to seek the suitable welding conditions such as the friction pressure, the friction speed and the upset pressure. The results obtained are as follows： Heat transfer to the specimens and the intermediate material during friction process was made clear; The operational conditions such as the rotation number of the intermediate material and the friction pressure to reach the liquidus in the interface could be estimated; Further, as the overhang length near the interface is well related to the joint efficiency, we tried to obtain the operational conditions by numerical analysis to acquire a certain length of the overhang length near the interface.

关键词： Numerical simulation friction welding intermediate material thermal elastic-plastic stress analysis aluminum alloy steel.

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Endoscopic ultrasound using ultrasound probes for the diagnosis of early esophageal and gastric cancers

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World Journal of Gastrointestinal Endoscopy 2012年第6期4卷 218-226页

作者： Shigetaka Yoshinaga Ichiro Oda Satoru Nonaka ryoji Kushima Yutaka Saito Endoscopy Division National Cancer Center Hospital5-1-1 TsukijiChuo-kuTokyo 104-0045Japan Pathology Division National Cancer Center Hospital5-1-1 TsukijiChuo-kuTokyo 104-0045Japan

Endoscopic ultrasound (EUS) devices were first designed and manufactured more than 30 years ago, and since then investigators have reported EUS is effective for determining both the staging and the depth of invasion of esophageal and gastric cancers. We review the present status, the methods, and the findings of EUS when used to diagnose and stage early esophageal and gastric cancer. EUS using high-frequency ultrasound probes is more accurate than conventional EUS for the evaluation of the depth of invasion of superficial esophageal carcinoma. The rates of accurate evaluation of the depth of invasion by EUS using high-frequency ultrasound probes were 70%-88% for intramucosal cancer, and 83%-94% for submucosal invasive cancer. But the sensitivity of EUS using high-frequency ultrasound probes for the diagnosis of submucosal invasive cancer was relatively low, making it difficult to confirm minute submucosal invasion. The accuracy of EUS using high-frequency ultrasound probes for early gastric tumor classification can be up to 80% compared with 63% for conventional EUS, although the accuracy of EUS using high-frequency ultrasound probes relatively decreases for those patients with depressed-type lesions, undifferentiated cancer, concomitant ulceration, expanded indications, type 0-I?lesions, and lesions located in the upper-third of the stomach. A 92% overall accuracy rate was achieved when both the endoscopic appearance and the findings from EUS using high-frequency ultrasound probes were considered together for tumor classification. Although EUS using high-frequency ultrasound probes has limitations, it has a high depth of invasion accuracy and is a useful procedure to distinguish lesions in the esophagus and stomach that are indicated for endoscopic resection.

关键词： Endoscopic ultrasound High-frequency ultrasound probe Esophageal cancer Gastric cancer Depth diagnosis

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Utility of linked color imaging for endoscopic diagnosis of early gastric cancer

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World Journal of Gastroenterology 2019年第10期25卷 1248-1257页

作者： Toshihisa Fujiyoshi ryoji Miyahara Kohei Funasaka Kazuhiro Furukawa Tsunaki Sawada Keiko Maeda Takeshi Yamamura Takuya Ishikawa Eizaburo Ohno Masanao Nakamura Hiroki Kawashima Masato Nakaguro Masahiro Nakatochi Yoshiki Hirooka Department of Gastroenterology and Hepatology Nagoya University Graduate School of Medicine Department of Endoscopy Nagoya University Hospital Department of Pathology and Laboratory Medicine Nagoya University Hospital Division of Data Science Data Coordinating CenterDepartment of Advanced MedicineNagoya University Hospital

BACKGROUND Linked color imaging(LCI) is a method of endoscopic imaging that emphasizes slight differences in red mucosal *** To evaluate LCI in diagnostic endoscopy of early gastric cancer and to compare LCI and pathological *** Endoscopic images were obtained for 39 patients(43 lesions) with early gastric cancer. Three endoscopists evaluated lesion recognition with white light imaging(WLI) and LCI. Color values in Commission Internationale de l'Eclairage(CIE)1976 L*a*b* color space were used to calculate the color difference(ΔE) between cancer lesions and non-cancer areas. After endoscopic submucosal dissection,blood vessel density in the surface layer of the gastric epithelium was evaluated pathologically. The identical region of interest was selected for analyses of endoscopic images(WLI and LCI) and pathological *** LCI was superior for lesion recognition(P < 0.0001), and ΔE between cancer and non-cancer areas was significantly greater with LCI than WLI(29.4 vs 18.6, P <0.0001). Blood vessel density was significantly higher in cancer lesions(5.96% vs4.15%, P = 0.0004). An a* cut-off of ≥ 24 in CIE 1976 L*a*b* color space identified a cancer lesion using LCI with sensitivity of 76.7%, specificity of 93.0%, and accuracy of 84.9%.CONCLUSION LCI is more effective for recognition of early gastric cancer compared to WLI as a result of improved visualization of changes in redness. Surface blood vessel density was significantly higher in cancer lesions, and this result is consistent with LCI image analysis.

关键词： Linked color imaging Early gastric cancer Endoscopic submucosal dissection Vessel density Color difference

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Surgical Treatment of Idiopathic Multiple Pulmonary Arteriovenous Malformation Identified at the Onset of Cerebral Infarction: A Case Report

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Open Journal of Respiratory Diseases 2017年第2期7卷 62-67页

作者： Masahiro kitada Shunsuke Yasuda Nana Takahashi Satoshi Okazaki Kei Ishibashi Satoshi Hayashi Yoshinobu Ohsaki Department of Respiratory Center Asahikawa Medical University Hokkaido Japan

Pulmonary arteriovenous malformation (PAVM), which is asymptomatic in most cases, is often identified in patients with central nervous system disorders such as brain abscesses and/or cerebral infarctions. We have reported a patient with idiopathic multiple PAVM identified at the onset of cerebral infarction. A 69-year-old woman visited the Department of Neuropathic Internal Medicine at our hospital with chief complaints of numbness in her left hand and a feeling of weakness. The patient was given a diagnosis of subacute cerebral infarction. Multiple old lacunar infarctions were also observed in the deep white matter of the left frontal lobe. Chest computed tomography showed multiple nodular structures, mainly in the right lower lung field (S8), as well as continuous arteries and veins at the site;thus, the patient was finally diagnosed with multiple PAVM. Right lower thoracoscopic lobectomy was performed, as is typical surgical practice in such cases. The patient had a favorable postoperative course, and had no recurrence of cerebral infarction. Although the patient’s lesions were mainly restricted to S8, the fact that there were multiple lesions deemed a lobectomy as the appropriate course of treatment. This case emphasizes that attention should be paid to cases of multiple PAVM since cerebral infarction may arise from the disease.

关键词： Pulmonary Arteriovenous Malformation (PAVM) Brain Abscesses Cerebral Infarctions

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The Friction Welding Method with Intermediate Material

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Journal of Mechanics Engineering and Automation 2013年第11期3卷 677-684页

作者： ryoji Tsujino Takeshi Higashi Kiyoshi Matsuura Yoshiaki Ueda Manabu Iguchi Faculty of Science and Engineering Setsunan University Neyagawa 672-8508 Japan Faculty of Engineering Setsunan University Neyagawa 672-8508 Japan Taiyu Corp. Neyagawa 572-0077 Japan Division of Materials Science and Engineering Graduate School of Engineering Hokkaido University Hokkaido 060-8628 Japan Faculty of Engineering Osaka Electro-Communication University Neyagawa 572-8530 Japan

For the purpose of improving the defects of the conventional friction welding method, the new friction welding technology has been examined. That is, the aim of the study is producing the joint of dissimilar materials evaluated to be difficult for friction welding and non-round shape joints. In this process, after the intermediate material generates the independent friction heat on every side of the specimens, it is removed instantaneously and upset process begins to weld the specimens for a joint. In this study, similar joint of A2017 aluminum alloy and one of S45C steel were examined. On the other hand, thermal elastic-plastic stress analysis by the finite element method was carried out using ANSYS mechanical.

关键词： Friction welding joint intermediate material aluminum alloy steel.

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Clinicopathological Study of Neuroendocrine Carcinoma of the Breast

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Journal of Cancer Therapy 2017年第8期8卷 793-799页

作者： Masahiro kitada Shunsuke Yasuda Masahiro Abe Nana Takahashi Satoshi Okazaki Kei Ishibashi Satoshi Hayashi Department of Breast Disease Center Asahikawa Medical University Asahikawa Japan

Introduction: Neuroendocrine carcinoma (NEC) occurs mostly in the digestive organs, such as the pancreas and gastrointestinal tract, and the lungs. Primary NEC of the breast is a rare entity. There are not many studies on this disease, and this study was carried out in order to know the clinical pathology of this disease. Methods: Of 2354 patients who underwent surgery for breast cancer in our hospital during the period from January 2000 to July 2015, 8 (0.34%) were pathologically diagnosed with NEC of the breast. This study is retrospectively registered. Result: The histological types were small cell carcinoma in one patient and invasive ductal carcinoma (IDC) with neuroendocrine differentiation in the remaining 7. The mean patient age was slightly higher than that of patients with usual IDC. On pathological examination, the NEC tumors were more hormone dependent and often HER2 negative, as compared to usual IDC, though there was no significant difference in nuclear grade. The patients with NEC of the breast showed positivity for neuroendocrine markers on immunohistological staining, and had favorable outcomes. Conclusion: NEC of the breast is rare, and there is no established consensus regarding the pathological significance, prognosis, and treatment method. Further accumulation of cases is necessary.

关键词： Breast Cancer Neuroendocrine Carcinoma

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Double-balloon endoscopic retrograde cholangiopancreatography for patients who underwent liver operation: A retrospective study

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World Journal of Gastroenterology 2020年第10期26卷 1056-1066页

作者： Ryo Nishio Hiroki Kawashima Masanao Nakamura Eizaburo Ohno Takuya Ishikawa Takeshi Yamamura Keiko Maeda Tsunaki Sawada Hiroyuki Tanaka Daisuke Sakai ryoji Miyahara Masatoshi Ishigami Yoshiki Hirooka Mitsuhiro Fujishiro Department of Gastroenterology and Hepatology Nagoya University Graduate School of MedicineAichi PrefectureNagoya 4668550Japan Department of Endoscopy Nagoya University HospitalAichi PrefectureNagoya 4668550Japan Department of Liver Biliary Tract and Pancreas DiseasesFujita Health University HospitalAichi PrefectureToyoake 4701192Japan

BACKGROUND Double-balloon endoscopic retrograde cholangiography (DB-ERC) is widely performed for biliary diseases after reconstruction in gastrointestinal surgery,but there are few reports on DB-ERC after hepatectomy or living donor liver transplantation (LDLT).AIM To examine the success rates and safety of DB-ERC after hepatectomy or LDLT METHODS The study was performed retrospectively in 26 patients (45 procedures) who underwent hepatectomy or LDLT (liver operation:LO group) and 40 control patients (59 procedures) who underwent pancreatoduodenectomy (control group).The technical success (endoscope reaching the choledochojejunostomy site),diagnostic success (performance of cholangiography),therapeutic success(completed interventions) and overall success rates,insertion and procedure(completion of DB-ERC) time,and adverse events were compared between these *** There were no significant differences between LO and control groups in the technical [93.3%(42/45) vs 96.6%(57/59),P=0.439],diagnostic [83.3%(35/42) vs83.6%(46/55),P=0.968],therapeutic [97.0%(32/33) vs 97.7%(43/44),P=0.836],and overall [75.6%(34/45) vs 79.7%(47/59),P=0.617] success *** median insertion time (22 vs 14 min,P <0.001) and procedure time (43.5 vs 30 min,P=0.033) were significantly longer in the LO *** incidence of adverse events showed no significant difference [11.1%(5/45) vs 6.8%(4/59),P=0.670].CONCLUSION DB-ERC after liver operation is safe and useful but longer time is required,so should be performed with particular care.

关键词： Biliary tract diseases Double-balloon enteroscopy Endoscopic retrograde cholangiopancreatography Hepatectomy Liver transplantation Risk management

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松材线虫的表被层蛋白(英文)

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南京林业大学学报（自然科学版） 2010年第2期34卷 150-151页

作者： ryoji Shinya Yuko Takeuchi Hironobu Morisaka Mitsuyoshi Ueda Kazuyoshi Futai 日本京都大学研究生院环境菌物研究室日本国科学促进会日本京都大学生物大分子研究室

线虫表被层在寄主-寄生者互作中起着多种关键作用。几种凝集素在不同虫龄的表被层中的结合能力测定证明,麦胚凝集素(WGA)仅结合到3龄繁殖幼虫及卵壳表面,但这种结合经常发生在毒性松材线虫分离物中,而不是低毒松材线虫分离物的表被层。... 详细信息

线虫表被层在寄主-寄生者互作中起着多种关键作用。几种凝集素在不同虫龄的表被层中的结合能力测定证明,麦胚凝集素(WGA)仅结合到3龄繁殖幼虫及卵壳表面,但这种结合经常发生在毒性松材线虫分离物中,而不是低毒松材线虫分离物的表被层。卵壳表面WGA的结合最强。WGA经常结合到线虫表被层上。表被层蛋白提取物的分析显示其碳氢化合物及蛋白质谱随线虫发育和对松树寄主的入侵而变化。研究结果表明,松材线虫的表被层蛋白在松树寄主和线虫间的互作中起着重要作用。

关键词：松材线虫麦胚凝集素表被层蛋白

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