检索结果-南通市图书馆

HT-SuperSAGE of the gut tissue of a Vip3Aa-resistant Heliothis virescens (Lepidoptera: Noctuidae) strain provides insights into the basis of resistance

引用

Insect Science 2019年第3期26卷 479-498页

作者： Camilo Ayra-Pardo Maria E. Ochagavia Ben Raymond Asim Gulzar Lianet Rodriguez-Cabrera Claudia Rodriguez de la Noval Ivis Moran Bertot ryohei terauchi Kentaro Yoshida Hideo Matsumura Pilar Tellez Rodriguez Daily Hernandez Hemandez Orlando Borras-Hidalgo Denis J. Wright Plant Division Centre for Genetic Engineering and Biotechnology (CIGB) Havana Cuba Department of Life Sciences Faculty of Natural Sciences Imperial College London Berkshire UK Genetics and Genomics Research Group Iwate Biotechnology Research Center Kitakami Japan Current addresses: University of Exeter Penryn campus Penryn Cornwall TR10 9FE UK Department of Entomology University of Arid Agriculture Rawalpindi Muree Road Rawalpindi 46300 Pakistan Laboratory of Plant Genetics Kobe University 1-1 Rokkodai-cho Nada ward Kobe 657-8501 Japan

Multitoxin Bt-crops expressing insecticidal toxins with different modes of action, for example, Cry and Vip, are expected to improve resistance management in target pests. While Cry1A resistance has been relatively well characterized in some insect species, this is not the case for Vip3A, for which no mechanism of resistance has yet been identified. Here we applied HT-SuperSAGE to analyze the transcriptome of the gut tissue of tobacco budworm Heliothis virescens (F.) laboratory-selected for Vip3Aa resistance. From a total of 1 324 252 sequence reads, 5 895 126-bp tags were obtained representing 17 751 nonsingleton unique transcripts (UniTags) from genetically similar Vip3Aa-resistant (Vip- Sel) and susceptible control (Vip-Unsel) strains. Differential expression was significant (≥2.5 fold or ≤0.4;P < 0.05) for 1989 sequences (11.2% of total UniTags), where 420 represented overexpressed (OE) and 1569 underexpressed (UE) genes in Vip-Sel. BLASTN searches mapped 419 UniTags to H. virescens sequence contigs, of which, 416 (106 OE and 310 UE) were unambiguously annotated to proteins in NCBI nonredundant protein databases. Gene Ontology distributed 345 of annotated UniTags in 14 functional categories with metabolism (including serine-type hydrolases) and translation/ribosome biogenesis being the most prevalent. A UniTag homologous to a particular member of the REsponse to PAThogen (REPAT) family was found among most overexpressed, while UniTags related to the putative Vip3Aa-binding ribosomal protein S2 (RpS2) were underexpressed. qRT-PCR of a subset of UniTags validated the HT-SuperSAGE data. This study is the first providing lepidopteran gut transcriptome associated with Vip3Aa resistance and a foundation for future attempts to elucidate the resistance mechanism.

关键词： Bt resistance Heliothis virescens HT-SuperSAGE transcriptomics Vip3Aa

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Performance of 18-fluoro-2-deoxyglucose positron emission tomography for esophageal cancer screening

引用

World Journal of Gastroenterology 2017年第15期23卷 2743-2749页

作者： Masau Sekiguchi Takashi terauchi Yasuo Kakugawa Naoki Shimada Yutaka Saito Takahisa Matsuda Cancer Screening Center National Cancer Center HospitalTokyo Endoscopy Division National Cancer Center HospitalTokyo Division of Screening Technology Center for Public Health SciencesNational Cancer CenterTokyo Department of Diagnostic Radiology National Cancer Center HospitalTokyo Department of Nuclear Medicine Cancer Institute HospitalJapanese Foundation for Cancer Research Department of Radiological Technology Radiological Diagnosis National Cancer Center HospitalTokyo

AIM To evaluate the performance of 18-fluoro-2-deoxyglucose positron emission tomography(FDG-PET) for esophageal cancer(EC) *** We retrospectively analyzed the data of consecutive asymptomatic individuals who underwent FDG-PET and esophagogastroduodenoscopy(EGD) simultaneously for cancer screening at our institution from February 2004 to March 2013. In total, 14790 FDG-PET and EGD procedures performed for 8468 individuals were included in this study, and the performance of FDGPET for EC screening was assessed by comparing the results of FDG-PET and EGD, considering the latter as the *** Thirty-two EC lesions were detected in 28 individuals(31 squamous cell carcinomas and 1 adenocarcinoma). The median tumor size was 12.5 mm, and the depths of the lesions were as follows: Tis(n = 12), T1a(n = 15), and T1b(n = 5). Among the 14790 FDG-PET procedures, 51 examinations(0.3%) showed positive findings in the esophagus; only 1 was a true-positive finding. The screen sensitivity, specificity, positive predictive value, and negative predictive value of FDGPET for ECs were 3.6%(95%CI: 0.1-18.3), 99.7%(95%CI: 99.6-99.7), 2.0%(95%CI: 0.0-10.4), and 99.8%(95%CI: 99.7-99.9), respectively. Of the 50 FDG-PET false-positive cases, 31 were observed in the lower esophagus, and gastroesophageal reflux disease was observed in 17 of these 31 *** This study is the first to clarify the FDG-PET performance for EC screening. Based on the low screen sensitivity, FDG-PET is considered to be difficult to use as a screening modality for ECs.

关键词： Cancer screening Esophageal cancer Esophagogastroduodenoscopy Positron emission tomography Screen sensitivity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The projection-specific signals that establish functionally segregated dopaminergic synapses

引用

四川生理科学杂志 2023年第9期45卷 1742-1742页

作者： Akiko terauchi Department of Neurology F.M. Kirby Neurobiology Center Boston Children’s Hospital Harvard Medical School Boston MA 02115 USA Department of Neurobiology and Howard Hughes Medical Institute Harvard Medical School Boston MA 02115 USA Department of Computer Science Northern Illinois University DeKalb IL 60115 USA State Key Laboratory of Membrane Biology PKU-IDG/McGovern Institute for Brain Research Peking-Tsinghua Center for Life Sciences Peking University Beijing 100871 China

Dopaminergic projections regulate various brain functions and are implicated in many neuropsychiatric disorders. There are two anatomically and functionally distinct dopaminergic projections connecting the midbrain to striatum: nigrostriatal, whichcontrols movement, and mesolimbic, which regulates motivation. However, how these discrete dopaminergic synaptic connections are established is unknown. Through an unbiased search, we identify that two groups of antagonistic TGF-β family members, bone morphogenetic protein (BMP)6/BMP2 and transforming growth factor (TGF)-β2, regulate dopaminergic synapse development of nigrostriatal and mesolimbic neurons, respectively. Projection-preferential expression of their receptors contributes to specific synapse development. Downstream, Smad1 and Smad2 are specifically activated and required for dopaminergic synapse development and function in nigrostriatal vs. mesolimbic projections. Remarkably, Smad1 mutant mice show motor defects, whereas Smad2 mutant mice show lack of motivation. These results uncover the molecular logic underlying the proper establishment of functionally segregated dopaminergic synapses and may provide strategies to treat relevant, projection-specific disease symptoms by targeting specific BMPs/TGF-β and/or Smads.

关键词： projection motivation specific

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

金属注射成形冷作工具钢的超声疲劳性能

引用

粉末冶金技术 2005年第2期23卷 88-90页

作者： K.Doi K.Hanami T.Teraoka S.terauchi T.Sugimoto 韩风麟 Osaka Yakin Kogyou Co.Ltd. Higashiyodogawa-KuOsaka 553-0005Japan Kansai University ORDIST Suita-shiOsaka 564-8680Japan

用超声疲劳试验研究了金属注射成形(MIM)冷作工具钢和锻轧钢(JISSKD11)的高周疲劳性能。锻轧钢试样于423K回火1h。另一方面,为了评估回火温度对疲劳性能的影响,将MIM钢试样于不同温度下进行了回火。在N=103～108疲劳寿命范围内进行了超... 详细信息

用超声疲劳试验研究了金属注射成形(MIM)冷作工具钢和锻轧钢(JISSKD11)的高周疲劳性能。锻轧钢试样于423K回火1h。另一方面,为了评估回火温度对疲劳性能的影响,将MIM钢试样于不同温度下进行了回火。在N=103～108疲劳寿命范围内进行了超声疲劳试验。MIM钢试样的疲劳强度和锻轧钢试样相同。MIM钢试样的疲劳强度随着回火温度升高而减低。显微组织的观察结果表明,MIM钢试样的碳化物的直径与形状比锻轧钢试样的均一。

关键词：金属注射成形冷作工具钢高周疲劳性能超声疲劳试验疲劳强度 MIM 试验研究回火温度疲劳寿命温度升高显微组织试样轧钢碳化物

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Female Preponderance in the Discordant Association between Retinopathy and Nephropathy in Patients with Type 2 Diabetes Mellitus

引用

International Journal of Clinical Medicine 2011年第1期2卷 13-17页

作者： Satsuki Kawasaki Shinobu Satoh Osamu Hasegawa Satoshi Morita Satoshi Kato Yasuo terauchi 不详

Aim: To elucidate clinical features in patients with type 2 diabetes with advanced retinopathy but without nephropathy. Methods: This study examined 1324 patients (784 males and 540 females) with type 2 diabetes mellitus. Diabetic reti-nopathy was graded according to the International Clinical Classification of Diabetic Retinopathy as no diabetic reti-nopathy, mild or moderate non-proliferative diabetic retinopathy, severe non-proliferative diabetic retinopathy, and proliferative diabetic retinopathy. Diabetic nephropathy was classified into four stages of severity according to the Guideline Committee of the Japan Diabetes Society. Each patient was examined for retinopathy grade and nephropathy stage. Clinical features of patients with proliferative diabetic retinopathy were compared with regard to the four grades of diabetic nephropathy. Results: Fifty-two patients with type 2 diabetes (3.9% of the whole series of 1324 patients with type 2 diabetes and 25.7% of patients with proliferative diabetic retinopathy) had proliferative diabetic retinopathy without the presence of nephropathy. Multiple statistical analysis using a proportional odds model revealed that pa-tients with proliferative diabetic retinopathy without nephropathy had a significantly lower systolic blood pressure (p < 0.001) than those who did and were preponderantly female (p < 0.05). Conclusions: A possible susceptibility of dia-betic females to proliferative advanced retinopathy without nephropathy encourages further studies on the role of hor-mones and blood coagulation in the pathogensis of proliferative diabetic retinopathy.

关键词： Discordance Female Gender preponderance Hormone Nephropathy Pathogenesis Proliferative Retinopathy Risk factor Type 2 diabetes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Basic Research on the Dye-Sensitized Solar Cells (DSSC)

The Basic Research on the Dye-Sensitized Solar Cells (DSSC)

引用

作者： Arini Nuran Binti Zulkifili terauchi Kento Matsutake Daiki Akira Fujiki School of Engineering Shibaura Institute of Technology (SIT)

The dye-sensitized solar cell(DSSC) is a new type of solar cell which converts the visible light into electricity by using the photoelectrochemical system. It is based on the sensitization of the wide band gap semiconductors which is made up of a sandwich-liked structure that consists of a semiconductor formed between a photo-sensitized anode and an electrolyte. In this research,we focused on the TiO photoelectrode by evaluating the particle size of titania,determining the effects of molecular binder PEG towards TiO paste preparation,as well as the effects of natural dye by comparing the blueberry,gardenia blue and yellow and red yeast dye,and evaluating the effect of the multilayer of TiO.

关键词： Dye-sensitized solar cell nano-particles TiO2 natural coloring polyethylene glycol(PEG)

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Orientation-controlled,low-temperature plasma growth and applications of h-BN nanosheets

引用

Nano Research 2019年第1期12卷 91-99页

作者： Ivan Sergeevich Merenkov Mikhail Sergeevich Myshenkov Yuri Mikhailovich Zhukov Yohei Sato Tatyana Sergeevna Frolova Denis Vasilevich Danilov Igor Alekseevich Kasatkin Oleg Sergeevich Medvedev Roman Vladimirovich Pushkarev Olga Iva no vna Sin itsyna Masami terauchi Irina Alekseev na Zvereva Marina Leonidovna Kosinova Ken Ostrikov Nikolaev Institute of Inorganic Chemistry SB RAS Novosibirsk 630090Russia Ural Federal University Ekaterinburg 620002Russia Saint-Petersburg State University St.Petersburg 199034Russia IMRAM Tohoku UniversitySendai 980-8577Japan Institute of Cytology and Genetics SB RAS Novosibirsk 630090Russia Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS Novosibirsk 630090Russia Novosibirsk State University Novosibirsk 630090Russia School of Physics Chemistry and Mechanical EngineeringQueensland University of TechnologyBrisbane QLD 4000Australia CSIRO-QUT Joint Sustainable Processes and Devices Laboratory P.O.Box 218Lindfield.NSW 2070Australia

Dimensionality and orientation of hexagonal boron nitride(h-BN)nanosheets are promising to create and control their unique properties for diverse ***,low-temperature deposition of vertically oriented h-BN nanosheets is a significant *** we report on the low-temperature plasma synthesis of maze-like h-BN nanowalls(BNNWs)from a mixture of triethylamine borane(TEAB)and ammonia at temperatures as low as 400℃.The maze-like BNNWs contained vertically aligned stacks of h-BN *** h-BN nanowalls with randomly oriented nanocrystalline structure are also *** and effective control of morphological type of BNNWs by the deposition-mperature is *** the lower synthesis temperature,thermal stability and oxidation resistivity of the maze-like BNNWs are higher than for the wavy *** structure and oxidation of the nanowalls was found to be the critical factor for their thermal stability and con trolled luminescence *** study dem on strated sign ificant antibacterial effect of both maze-like and wavy h-BN nanowalls against *** reported results reveal a significant potential of h-BN nanowalls for a broad range of applications from electronics to biomedicine.

关键词： boron nitride nanosheets nanowalls chemical vapor deposition cytotoxicity light emission thermal stability

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Implication for Designing a REDD+ Program in a Frontier of Oil Palm Plantation Development: Evidence in East Kalimantan, Indonesia

引用

Open Journal of Forestry 2014年第3期4卷 259-277页

作者： Daisuke terauchi Ndan Imang Martinus Nanang Masayuki Kawai Mustofa Agung Sardjono Fadjar Pambudhi Makoto Inoue Center for Social Forestry Mulawarman University Samarinda Indonesia Department of Global Agricultural Sciences Graduate School of Agricultural and Life Sciences The University of Tokyo Tokyo Japan Department of Human Geography Graduate School of Arts and Sciences The University of Tokyo Tokyo Japan

To examine the REDD+ (Reducing Emissions from Deforestation and Forest Degradation) program as an alternative to an oil palm plantation in West Kutai district of East Kalimantan, we determined the profitability of land use and REDD+, and the land use preferences and practices of the local people, as well as their participation in and preferences for forestry programs. Our findings indicate the following: 1) the profitability of an oil palm plantation was higher than that from other land uses and the REDD+ program;2) the local preferences for land uses were mostly consistent with the profitability of the land uses, except for oil palm plantation due to non-financial concerns;3) the local people combined each land use in accordance with their various needs;and 4) the local people were interested in a Forest and Land Rehabilitation (RHL) program in nonforestry zones. Considering these evidences, an improved RHL program based on an intensive agroforestry system and a conservation-based REDD+ program based on existing customary conservation forest management by the local people are proposed. Given the high opportunity cost and the low preference for an oil palm plantation, designing the REDD+ program by paying attention to the non-financial benefits for a community is a way forward. To enhance the non-financial benefits, it is important to take into consideration local preferences and livelihood activities in designing the REDD+ program. This study also implies the need for a reconsideration of the position of participation of local people in the safeguards of REDD+.

关键词： REDD+ Oil Palm Plantation Local People Land Use Preference Land Use Profitability

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于MRI影像组学鉴别乳腺叶状肿瘤与纤维腺瘤

引用

国际医学放射学杂志 2022年第4期 494-495页

作者： M.Tsuchiya T.Masui K.terauchi T.Yamada M.Katyayama S.Lchikawa 张晓涵

摘要目的评估基于MRI影像组学模型鉴别乳腺叶状肿瘤与纤维腺瘤的诊断效能。方法回顾性纳入MRI检查的88例病人（叶状肿瘤32例、纤维腺瘤56例）。基于T2WI、

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Local Structure Analysis of an Automobile Catalyst La1.02Fe0.95Pd0.05O3 by Pd K-edge XAFS

Local Structure Analysis of an Automobile Catalyst La1.02Fe0...

引用

亚洲晶体学联合大会

作者： Shoshi Higuchi Daiju Matsumura Yasuo Nishihata Jun’iciro Mizuki Hikaru terauchi Isao Takahashi Masashi Taniguchi Mari Uenishi Hirohisa Tanaka Kimiyoshi Kaneko Kwansei-Gakuin University 2-1 GakuenSanda Hyogo 669-1337Japan Synchrotron Radiation Research Center Japan Atomic Energy AgencySayoHyogo 679-5148Japan

＜正＞A La1.02Fe0.95Pd0.05O3（LFPO） catalyst has special feature which maintains high catalytic property even in long time use, while an alumina catalyst employs a sufficient excess of precious metals to ensure the a...

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：