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花瓣纹源起试想——从刘林遗址和大墩子遗址彩陶钵谈起

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陶瓷研究 2020年第3期35卷 35-40页

作者：金濡欣江苏建筑职业技术学院徐州市221000

本文从刘林遗址和大墩子遗址出土的彩陶器出发,综合庙底沟文化类型中的彩陶现象,从"第一次的闲适""自然主义的描绘""心智的大开发""地域传播与文化认同"四个角度试论花瓣纹在新石器时代的出现与源起。

关键词：彩陶花瓣纹农耕文明自然主义世俗化地域传播

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陶瓷的符号与语义系统试探

中国陶瓷工业 2019年第5期26卷 14-18页

作者：金濡欣江苏建筑职业技术学院

提出了艺术家与传统、艺术与社会、个体语言与传统语言的制约关系,从结构主义语言学和符号学的理论出发,阐释中国传统陶瓷文化的符号与语义系统,试以语言学和符号学的理论寻求陶瓷设计方法论的可能性,获得重新思索和打开一扇窗的途径。

关键词：个体语言传统语言结构语言学符号学

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徐州汉画石图像中的汉风民居装饰艺术探究

江苏建筑职业技术学院学报 2015年第4期15卷 45-48页

作者：金濡欣江苏建筑职业技术学院建筑设计与装饰学院江苏徐州221116

为了更好地发掘与探究徐州地域传统民居装饰的艺术特点与文化特质,结合史料及文献记载,以徐州特有的汉画像石建筑图像为研究对象,从中溯源具有汉风传统的民居装饰艺术内涵与价值.从民居建筑的入户、室内界面与陈设、建筑庭院3个方面进... 详细信息

为了更好地发掘与探究徐州地域传统民居装饰的艺术特点与文化特质,结合史料及文献记载,以徐州特有的汉画像石建筑图像为研究对象,从中溯源具有汉风传统的民居装饰艺术内涵与价值.从民居建筑的入户、室内界面与陈设、建筑庭院3个方面进行研究和论证.结果表明:徐州汉风传统乐于将装饰与文化寓意相结合,将美好理想赋予民居装饰.其民居装饰的背后饱含浓厚的文化理念,表现出开朗、乐观、自信的生活态度.

关键词：传统民居汉画像石汉风装饰艺术徐州地域

陶瓷艺术批评刍议——器物陶瓷艺术的“失语”与当下“言说”

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陶瓷研究 2019年第3期34卷 54-55页

作者：金濡欣江苏建筑职业技术学院

本文以器物陶瓷为讨论对象,试厘清“陶瓷艺术”之概念,梳理当下与传统之关系,提出当下器物陶瓷艺术的“失语”状态,进而对陶瓷艺术的自性与本体身份进行再确认,明确语境并探讨陶瓷艺术的当下“言说”。

关键词：器物陶瓷陶瓷艺术本体身份当下言说

Brain-derived neurotrophic factor and neural plasticity in a rat model of spinal cord transection

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Neural Regeneration Research 2011年第13期6卷 1017-1022页

作者： ruxin Xing Jia Liu Hua jin Ping Dai Tinghua Wang Department of Neurosurgery West China Hospital of Sichuan University Chengdu 610041 Sichuan Province China Institute of Neuroscience Kunming Medical College Kunming 650031 Yunnan Province China Laboratory of Neurological Disease West China Hospital of Sichuan University Chengdu 610041 Sichuan Province China

The present study employed a rat model of T10 spinal cord transection. Western blot analyses revealed increased brain-dedved neurotrophic factor （BDNF） expression in spinal cord segments caudal to the transection site following injection of replication incompetent herpes simplex virus vector （HSV-BDNF） into the subarachnoid space. In addition, hindlimb locomotor functions were improved. In contrast, BDNF levels decreased following treatment with replication defective herpes simplex virus vector construct small interference BDNF （HSV-siBDNF）. Moreover, hindlimb locomotor functions gradually worsened. Compared with the replication incompetent herpes simplex virus vector control group, extracellular signal regulated kinasel/2 expression increased in the HSV-BDNF group on days 14 and 28 after spinal cord transection, but expression was reduced in the HSV-siBDNF group. These results suggested that BDNF plays an important role in neural plasticity via extracellular signal regulated kinasel/2 signaling pathway in a rat model of adult spina cord transection.

关键词： spinal cord transection brain-dedved neurotrophic factor neuroplasticity extracellular-signal regulated kinasel/2 replication-incompetent herpes simplex virus vector replication-defective herpes simplex virus vector

Lightweight Method for Plant Disease Identification Using Deep Learning

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Intelligent Automation & Soft Computing 2023年第7期37卷 525-544页

作者： Jianbo Lu ruxin Shi jin Tong Wenqi Cheng Xiaoya Ma Xiaobin Liu Guangxi Key Lab of Human-machine Interaction and Intelligent Decision Nanning Normal UniversityNanning530001China School of Computer and Information Engineering Nanning Normal UniversityNanning530001China School of Logistics Management and Engineering Nanning Normal UniversityNanning530001China Hangzhou Hikvision Digital Technology Co.Ltd. Hangzhou310052China

In the deep learning approach for identifying plant diseases,the high complexity of the network model,the large number of parameters,and great computational effort make it challenging to deploy the model on terminal devices with limited computational *** this study,a lightweight method for plant diseases identification that is an improved version of the ShuffleNetV2 model is *** the proposed model,the depthwise convolution in the basic module of ShuffleNetV2 is replaced with mixed depthwise convolution to capture crop pest images with different resolutions;the efficient channel attention module is added into the ShuffleNetV2 model network structure to enhance the channel features;and the ReLU activation function is replaced with the ReLU6 activation function to prevent the gen-eration of large *** are conducted on the public dataset *** results show that the proposed model achieves an accuracy of 99.43%,which is an improvement of 0.6 percentage points compared to the ShuffleNetV2 *** to lightweight network models,such as MobileNetV2,MobileNetV3,EfficientNet,and EfficientNetV2,and classical convolutional neural network models,such as ResNet34,ResNet50,and ResNet101,the proposed model has fewer parameters and higher recognition accuracy,which provides guidance for deploying crop pest identification methods on resource-constrained devices,including mobile terminals.

关键词： Plant disease identification mixed depthwise convolution lightweight ShuffleNetV2 attention mechanism

Cytokine receptor-like factor 1(CRLF1)promotes cardiac fibrosis via ERK1/2 signaling pathway

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2023年第8期24卷 682-697页

作者： Shenjian LUO Zhi YANG ruxin CHEN Danming YOU Fei TENG Youwen YUAN Wenhui LIU jin LI Huijie ZHANG Department of Endocrinology and Metabolism Nanfang HospitalSouthern Medical UniversityGuangzhou 510515China Guangdong Provincial Key Laboratory of Shock and Microcirculation Southern Medical UniversityGuangzhou 510515China State Key Laboratory of Organ Failure Research Nanfang HospitalSouthern Medical UniversityGuangzhou 510515China Department of Endocrinology Shanxi Medical University Affiliated Second HospitalTaiyuan 030001China

Cardiac fibrosis is a cause of morbidity and mortality in people with heart ***-fibrosis treatment is a significant therapy for heart disease,but there is still no thorough understanding of fibrotic *** study was carried out to ascertain the functions of cytokine receptor-like factor 1(CRLF1)in cardiac fibrosis and clarify its regulatory *** found that CRLF1 was expressed predominantly in cardiac *** expression was up-regulated not only in a mouse heart fibrotic model induced by myocardial infarction,but also in mouse and human cardiac fibroblasts provoked by transforming growth factor-β1(TGF-β1).Gain-and loss-of-function experiments of CRLF1 were carried out in neonatal mice cardiac fibroblasts(NMCFs)with or without TGF-β1 ***1 overexpression increased cell viability,collagen production,cell proliferation capacity,and myofibroblast transformation of NMCFs with or without TGF-β1 stimulation,while silencing of CRLF1 had the opposite *** inhibitor of the extracellular signal-regulated kinase 1/2(ERK1/2)signaling pathway and different inhibitors of TGF-β1 signaling cascades,comprising mothers against decapentaplegic homolog(SMAD)-dependent and SMAD-independent pathways,were applied to investigate the mechanisms ***1 exerted its functions by activating the ERK1/2 signaling ***,the SMAD-dependent pathway,not the SMAD-independent pathway,was responsible for CRLF1 up-regulation in NMCFs treated with TGF-β*** summary,activation of the TGF-β1/SMAD signaling pathway in cardiac fibrosis increased CRLF1 ***1 then aggravated cardiac fibrosis by activating the ERK1/2 signaling ***1 could become a novel potential target for intervention and remedy of cardiac fibrosis.

关键词： Cytokine receptor-like factor 1(CRLF1) TGF-β1/SMAD signaling pathway ERK1/2 signaling pathway Cardiac fibrosis Myofibroblast transformation Extracellular matrix(ECM)

Alternate day fasting aggravates atherosclerosis through the suppression of hepatic ATF3 in Apoe^(-/-)mice

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Life Metabolism 2024年第3期3卷 46-59页

作者： Yajuan Deng Xiaoyu Yang Xueru Ye Youwen Yuan Yanan Zhang Fei Teng Danming You Xuan Zhou Wenhui Liu Kangli Li Shenjian Luo Zhi Yang ruxin Chen Guojun Shi jin Li Huijie Zhang Department of Endocrinology and Metabolism Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong 510515China Guangdong Provincial Key Laboratory of Shock and Microcirculation Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong 510515China State Key Laboratory of Organ Failure Research National Clinical Research Center for Kidney DiseaseNanfang HospitalSouthern Medical UniversityGuangzhouGuangdong 510515China Department of Endocrinology The Second Hospital of Shanxi Medical UniversityShanxi Medical UniversityTaiyuanShanxi 030001China Department of Endocrinology and Metabolism Guangdong Provincial Key Laboratory of DiabetologyThe Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong 510630China

Atherosclerosis is the major contributor to cardiovascular mortality *** day fasting(ADF)has gained growing attention due to its metabolic ***,the effects of ADF on atherosclerotic plaque formation remain inconsistent and controversial in atherosclerotic animal *** present study was designed to investigate the effects of ADF on atherosclerosis in apolipoprotein E-deficient(Apoe^(-/-))***-week-old male Apoe^(-/-)mice fed with Western diet(WD)were randomly grouped into ad libitum(AL)group and ADF group,and ADF aggravated both the early and advanced atherosclerotic lesion formation,which might be due to the disturbed cholesterol profiles caused by ADF *** significantly altered cholesterol metabolism pathways and down-regulated integrated stress response(ISR)in the *** hepatic expression of activating transcription factor 3(ATF3)was suppressed in mice treated with ADF and hepatocyte-specific overexpression of Aft3 attenuated the effects of ADF on atherosclerotic plaque formation in Apoe^(-/-)***,the expression of ATF3 could be regulated by Krüppel-like factor 6(KLF6)and both the expressions of ATF3 and KLF6 were regulated by hepatic cellular ISR *** conclusion,ADF aggravates atherosclerosis progression in Apoe^(-/-)mice fed on *** inhibits the hepatic ISR signaling pathway and decreases the expression of KLF6,subsequently inhibiting ATF3 *** suppressed ATF3 expression in the liver mediates the deteriorated effects of ADF on atherosclerosis in Apoe^(-/-)*** findings suggest the potentially harmful effects when ADF intervention is applied to the population at high risk of atherosclerosis.

关键词： alternate day fasting atherosclerosis cholesterol integrated stress response activating transcription factor 3

Simulation of Electric Field Distribution in Cable Joint under the Influence of Metal Particle

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Simulation of Electric Field Distribution in Cable Joint und...