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The association between Tai Chi exercise and safe driving performance among older adults： An observational study

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Journal of Sport and Health Science 2018年第1期7卷 83-94页

作者： Sally Miller ruth e.Taylor-Piliae School of Nursing Vanderbilt University Nashville TN 37240 USA College of Nursing The University of Arizona Tucson AZ 85721 USA

Background: Age-related cognitive and physical decline can impair safe driving performance. Tai Chi exercise benefits cognitive and physical function and may influence safe driving performance in older adults. The primary aim of this observational study was to compare cognitive processes and physical function related to safe driving performance among older adult Tai Chi practitioners to normative reference *** aims were to examine relationships between Tai Chi exercise habits, cognitive processes, and physical function related to safe driving performance and to explore potential predictors of safe driving ***: The Driving Health Inventory, the Driving Scenes Test, other driving-related cognitive and physical measures, and self-reported measures including the Mindful Attention Awareness Scale(MAAS) and the Vitality Plus Scale(VPS) were collected from current Tai Chi practitioners(n = 58; age 72.9 ± 5.9 years, mean ± SD) with median >3 years Tai Chi ***: Compared to normative reference values, participants performed better on numerous cognitive measures including the Driving Scenes Test(p ze navigation(p = 0.017, d = 0.27), the Useful Field of View Test(p easures including the Rapid Walk Test(p e Right Foot Tapping Test,(p ed higher than normative reference values on MAAS and VPS(p espectively). Statistically significant correlations were found between several study measures. The digit span backward test was the strongest predictor of safe driving performance(β = 0.34,p = 0.009).Conclusion: Tai Chi exercise has the potential to impact cognitive processes and physical function related to safe driving performance. Further study using randomized controlled trials, structured Tai Chi exercise doses, and driving simulator or on-road driving performance as outcome measures

关键词： Automobile driving Driving performance exercise Older adults Physical activity Tai Chi

Induction of ischemic tolerance as a promising treatment against diabetic retinopathy

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Neural Regeneration Research 2014年第17期9卷 1581-1584页

作者： ruth e.Rosenstein Diego C.Fernandez Laboratory of Retinal Neurochemistry and experimental Ophthalmology Department of Human BiochemistrySchool of Medicine/CEFyBOUniversity of Buenos Aires/CONICET Present address:Johns Hopkins University Department of Biology

Diabetic retinopathy is a leading cause of acquired blindness, and it is the most common ischemic disorder of the retina. Available treatments are not very effective. efforts to inhibit diabetic reti- nopathy have focused either on highly specific therapeutic approaches for pharmacologic targets or using genetic approaches to change expression of certain enzymes. However, it might be wise to choose innovative treatment modalities that act by multiple potential mechanisms. The resis- tance to ischemic injury, or ischemic tolerance, can be transiently induced by prior exposure to a non-injurious preconditioning stimulus. A complete functional and histologic protection against retinal ischemic damage can be achieved by previous preconditioning with non-damaging isch- emia. In this review, we will discuss evidence that supports that ischemic conditioning could help avert the dreaded consequences that results from retinal diabetic damage.

关键词： diabetic retinopathy ischemic tolerance retina ischemic injury ischemic conditioning

A rapid and cost effective protocol for plant genomic DNA isolation using regenerated silica columns in combination with CTAB extraction

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Journal of Integrative Agriculture 2017年第8期16卷 1682-1688页

作者： FU ze-yu SONG Jian-cheng Paula e.Jameson School of Biological Sciences University of Canterbury School of Life Sciences Yantai University

Isolation of high quality DNA from multiple samples can be both time-consuming and expensive. We have developed a combined protocol to reduce the time component of the hexadecyltrimethylammonium bromide （CTAB） extraction method and reduced costs by regenerating the silica columns used to purify genomic DNA. We present data that shows, by in- creasing the temperature used during the CTAB method, the time required to extract crude genomic DNA can be reduced. We show that silica columns can be regenerated using HCI and still maintain their DNA-binding capacity. Furthermore, we show both spectrophotometrically, and by restriction enzyme cutting, that the quality of the eluted DNA is high. Critically, using both genomic DNA from pea and perennial ryegrass we demonstrate, using species-specific PCR primers, that there is no carry-over of DNA from repeated use of a single column. The main advantages of the method are high yield, high quality, cost effectiveness and time-saving. This method could satisfy demand when large numbers of plant genomic DNA samples are required, for example from targeting induced local lesions in genomes （TILLING） populations.

关键词： CTAB DNA isolation silica columns

Highly selective and eco-friendly dihydroisoquinoline synthesis via Cu/Co synergistic catalysis in Cu NPs@MOFs catalyst under mild conditions

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Science China Chemistry 2024年第5期67卷 1561-1568页

作者： Peng-Fei Guo ze-Long Liang Yue-e Jiao Hang Xu Bin Zhao Key Laboratory of Advanced energy Material Chemistry Renewable Energy Conversion and Storage CenterDepartment of ChemistryNankai UniversityTianjin 300071China

3,4-Dihydroisoquinoline(DHIQ)is an important precursor used in the production of drugs for treating cancer,HIV,Alzheimer's disease,*** studies on DHIQ synthesis show low catalytic selectivity due to the susceptible over-oxidation feedstock of1,2,3,4-tetrahydroisoquinoline(THIQ),which often requires alkali ***,it is desirable yet challenging to explore a highly selective and efficient oxydehydrogenation capacity for DHIQ synthesis under eco-friendly reaction ***,a novel framework 1 was synthesized,exhibiting 1D channels with the size of 4.6 A×9.6 A and high solvent/p H/thermal stability.A stable framework allows it to encapsulate Cu nanoparticles(NPs)to form Cu NPs@1-x(x=1,2,3,and 4)with varying loading amounts of Cu NPs at 2.0 wt%,3.0 wt%,4.0 wt%,and 6.0 wt%,*** NPs@1-3 could selectively catalyze the reaction from THIQ to DHIQ with a high selectivity of 98%and a recorded turnover frequency(TOF)of 22.1 h-1under eco-friendly mild *** corresponding catalytic activity can maintain at least five recyclings and can be further applied to gram-scale ***,the efficient preparation of DHIQ catalyzed by Cu NPs@1-3 could be realized even under air ***,the anticancer molecule precursor synthesis of 6,7-dimethoxy-3,4-dihydroisoquinoline was also selectively catalyzed by Cu NPs@*** investigations revealed that high catalytic performance can be attributed to the stable framework and the synergistic catalytic effect of the loaded Cu NPs and Co metal *** importantly,this work represents the first example of MOF catalysts for selectively thermo-catalytic DHIQ synthesis and demonstrates a simple approach to obtain efficient catalysts for selective oxydehydrogenation in the production of unsaturated compounds.

关键词： metal-organic frameworks Cu NPs@MOFs 3 4-dihydroisoquinoline selective oxydehydrogenation synergistic catalysis

Diagnosing holographic type dark energy models with the Statefinder hierarchy, composite null diagnostic and w-w′pair

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Science China(Physics,Mechanics & Astronomy) 2018年第3期61卷 65-76页

作者： ze Zhao Shuang Wang CAS Key Laboratory of Theoretical Physics Institute of Theoretical Physics Chinese Academy of Sciences School of Physical Science University of Chinese Academy of Sciences School of Astronomy and Space Science Sun Yat-Sen University

The main purpose of this work is to distinguish various holographic type dark energy （De） models, including the AHDe, HDe, NADe, and RDe model, by using various diagnostic tools. The first diagnostic tool is the Statefinder hierarchy, in which the evolution of Statefinder hierarchy parmeter S3（1）（z） and S4（1）（z） are studied. The second is composite null diagnostic （CND）, in which the trajectories of {S（1）4, ∈} and {S4（1）, e} are investigated, where ∈ is the fractional growth parameter. The last is w-w′ analysis, where w is the equation of state for De and the prime denotes derivative with respect to lna. In the analysis we consider two cases： varying current fractional De density Ωde0 and varying De model parameter C. We find that：（1） both the Statefinder S4（1） can lead to larger hierarchy and the CND have qualitative impact on AHDe, but only have quantitative impact on HDe. （2） S4（1） differences than S 4（1）, while the CND pair has a stronger ability to distinguish different models than the Statefinder hierarchy. （3） For the case of varying C, the {w, w′} pair has qualitative impact on AHDe; for the case of varying Ωde0, the {w, w′} pair only has quantitative impact; these results are different from the cases of HDe, RDe, and NADe, in which the {w, w′} pair only has quantitative impact on these models. In conclusion, compared with HDe, RDe, and NADe, the AHDe model can be easily distinguished by using these diagnostic tools.

关键词： dark energy cosmology cosmological constant

In vitro angiogenesis in response to biomaterial properties for bone tissue engineering:a review of the state of the art

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Regenerative Biomaterials 2023年第1期10卷 744-783页

作者： else ellermann Nima Meyer ruth e.Cameron Serena M.Best Department of Materials Science and Metallurgy University of CambridgeCambridge CB30FSUK

Bone tissue engineering(BTe)aims to improve the healing of bone fractures using scaffolds that mimic the native extracellular *** successful bone regeneration,scaffolds should promote simultaneous bone tissue formation and blood vessel growth for nutrient and waste ***,a significant challenge in regenerative medicine remains the development of grafts that can be vascularized *** other things,optimization of physicochemical conditions of scaffolds is key to achieving appropriate angiogenesis in the period immediately following *** phosphates and collagen scaffolds are two of the most widely studied biomaterials for BTe,due to their close resemblance to inorganic and organic components of bone,respectively,and their bioactivity,tunable biodegradability and the ability to produce tailored *** various strategies exist to enhance vascularization of these scaffolds in vivo,further in vitro assessment is crucial to understand the relation between physicochemical properties of a biomaterial and its ability to induce *** mono-culture studies can provide evidence regarding cell-material interaction of a single cell type,a co-culture procedure is crucial for assessing the complex mechanisms involved in angiogenesis.A co-culture more closely resembles the natural tissue both physically and biologically by stimulating natural intercellular interactions and mimicking the organization of the in vivo ***,a co-culture is a complex system requiring optimization of various parameters including cell types,cell ratio,culture medium and seeding *** fundamental knowledge of the mechanism behind the bioactivity of biomaterials and understanding the contribution of surface and architectural features to the vascularization of scaffolds,and the biological response in general,can provide an invaluable basis for future optimization *** review gives an overview of the

关键词： angiogenesis collagen scaffolds hydroxyapatite co-culture architectural features physicochemical properties

Consequences of early life stress on the structure and function of the adult mouse retina

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Neural Regeneration Research 2024年第1期19卷 150-151页

作者： Juan S.Calanni ruth e.Rosenstein Laboratory of Retinal Neurochemistry and experimental Ophthalmology Department of Human BiochemistrySchool of Medicine/CEFyBOUniversity of Buenos Aires/CONICETBuenos AiresArgentina

early-life stress(eLS)refers to a period of environmental/social deprivation,physica l,sexual or emotional abuse,neglect,severe and/or chronic trauma in the prenatal/early postnatal stage,which is closely related to many adverse psychiatric disorders later in life,such as depressive disorder,substance abuse,dysthymia,panic,anxiety,and suicidal behavior in adulthood(Waters and Gould,2022).

关键词： stress life Gould

Improving the electrochemical performance of α-MoO_(3) electrode using aluminium trifluoromethanesulfonate water-in-salt electrolyte

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Journal of energy Chemistry 2023年第3期78卷 123-134,I0004页

作者： Ayman e.elkholy Timothy T.Duignan ruth Knibbe Xiu Song Zhao School of Chemical engineering The University of QueenslandSt Lucia CampusBrisbane 4072Australia School of Mechanical and Mining engineering The University of QueenslandSt Lucia CampusBrisbane 4072Australia

Orthorhombic molybdenum trioxide(α-MoO_(3)) electrode material experiences severe capacity fading and poor cycling stability in aqueous *** investigated the charge-storage performance of α-MoO_(3) electrode in aluminium trifluoromethanesulfonate(Al(OTf)_(3))-based salt-in-water electrolyte(SiWe) and water-in-salt electrolyte(WiSe).It was found that α-MoO_(3) electrode exhibits significantly different cycling stabilities in both electrolytes with capacity retentions of 8% using the former and87% using the *** is because α-MoO_(3) electrode maintains its crystal structure upon cycling in WiSe,but experiences substantial structural collapses and partial dissolution upon cycling in *** behaviour was inferred from both operando electrogravimetry and ex situ *** results suggest that the predominant charge-storage mechanism in a-MoO_(3) electrode using WiSe is the intercalation of protons produced from electrolyte hydrolysis with some contribution from surface pseudocapacitance enabled by Al3+ions.A two-volt full cell fabricated from α-MoO_(3) electrode as anode and copper hexacyanoferrate(CuHCF) electrode as cathode using WiSe delivers volumetric and gravimetric energies of 10.4 Wh/L and 26.5 Wh/kg,respectively,with 78% capacity retention after 2500 *** study provides an insightful understanding of the electrochemical performance of α-MoO_(3) electrode in Al(OTf)_(3)-based electrolytes.

关键词： Molybdenum oxide Aqueous electrolyte Water-in-salt electrolyte Aqueous batteries Pseudocapacitance

Genus two correlation functions in CFTs with TT deformation

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Science China(Physics,Mechanics & Astronomy) 2023年第5期66卷 106-119页

作者： Song He Yun-ze Li Center for Theoretical Physics and College of Physics Jilin UniversityChangchun 130012China Max Planck Institute for Gravitational Physics(Albert einstein Institute) Am Mühlenberg 114476 GolmGermany

Since the definition of TT deformation in the curved Riemann surface is obstructive in the literature,we propose a way to do the deformation in the genus two Riemann surfaces by sewing *** construct the correlation functions of conformal field theories(CFTs)on genus two Riemann surfaces with the TT deformation in terms of the perturbative CFT *** to sewing construction to form higher genus Riemann surfaces from lower genus ones and conformal symmetry,we systematically obtain the first-order TT correction to the genus two correlation functions in the TT deformed CFTs,e.g.,partition function and one/higher-point correlation functions.

关键词： conformal field theory gauge/gravity duality TT deformation higher genus correlation function