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造血干细胞移植后多重耐药菌血流感染的研究进展

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重庆医学 2025年第2期54卷 521-527页

作者：张若楠刘林重庆医科大学附属第一医院血液内科重庆400016

血流感染(BSI)是造血干细胞移植(HSCT)后一种常见的感染并发症。由于免疫抑制,移植患者较易发生BSI,一旦合并耐药菌感染,临床预后极差,严重影响患者的长期生存。近年来,随着广谱抗生素的广泛应用,HSCT患者BSI的病原菌分布和抗生素耐药... 详细信息

血流感染(BSI)是造血干细胞移植(HSCT)后一种常见的感染并发症。由于免疫抑制,移植患者较易发生BSI,一旦合并耐药菌感染,临床预后极差,严重影响患者的长期生存。近年来,随着广谱抗生素的广泛应用,HSCT患者BSI的病原菌分布和抗生素耐药模式发生重要变迁,由多重耐药菌引起的BSI呈逐年增加的趋势,成为全球抗感染治疗中非常棘手的问题。因此,及时对HSCT患者细菌性BSI的流行病学、抗生素防治策略及多重耐药菌感染管理的最新进展进行总结,对优化患者的抗感染治疗,提高移植总疗效具有重要意义。

关键词：造血干细胞移植多重耐药菌血流感染感染管理

Energy-efficient data collection for UAV-assisted IoT: Joint trajectory and resource optimization

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Chinese Journal of Aeronautics 2022年第9期35卷 95-105页

作者： Xiao TANG Wei WANG Hongliang HE ruonan zhang School of Electronics and Information Northwestern Polytechinical UniversityXi'an 710072China National Mobile Communications Research Laboratory Southeast UniversityNanjing 210096China College of Electronic and Information Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China College of Information Science and Technology College of Cyber SecurityJinan UniversityGuangzhou 510632China

Internet of Things(IoT) can be conveniently deployed while empowering various applications, where the IoT nodes can form clusters to finish certain missions collectively. As energyefficient operations are critical to prolong the lifetime of the energy-constrained IoT devices, the Unmanned Aerial Vehicle(UAV) can be dispatched to geographically approach the IoT clusters towards energy-efficient IoT transmissions. This paper intends to maximize the system energy efficiency by considering both the IoT transmission energy and UAV propulsion energy, where the UAV trajectory and IoT communication resources are jointly optimized. By applying largesystem analysis and Dinkelbach method, the original fractional optimization is approximated and reformulated in the form of subtraction, and further a block coordinate descent framework is employed to update the UAV trajectory and IoT communication resources iteratively. Extensive simulation results are provided to corroborate the effectiveness of the proposed method.

关键词： Block coordinate descent Data collection Dinkelbach method Energy efficiency Internet of Things(IoT) Unmanned aerial vehicle

A judicious approach to induce large size growth of hydroxyapatite via applying graphene modified silicon nitride nanowires

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Journal of Materiomics 2024年第2期10卷 490-498页

作者： Lina Sun Leilei zhang ruonan zhang Hejun Li State Key Laboratory of Solidification Processing Shanxi Key Laboratory of Fiber Reinforced Light Composite MaterialsNorthwestern Polytechnical UniversityXi'an710072China

Mimicking the structure of natural bone collagen fibers/hydroxyapatite(HA)to synthesize large size of HA for accelerated bone repair remains a ***,silicon nitride nanowires(SN)-graphene(GE)was designed by the chemical vapor deposition,forming SN-GE(SG)similar to collagen ***,the large size HA was assembled onto SG by pulsed electrochemical deposition,the SG/HA(SGH)mimics the collagen fibers/HA structure of *** introduction of SG induces HA to large size grow in the form of *** can be grown on a large size inextricably with the existence of GE modified *** the one hand,the upright GE sheets effectively increases the surface roughness which enhances the nucleation site of *** the other hand,the C=O provides chemical bonding and induces HA *** with SN/HA(SH),the porosity of SGH decreased by 71%.The average diameter of the SGH is(9.76±0.25)*** with SH,the diameter of SGH is 22 times larger than the diameter of *** that SG induces large size growth of *** work can provide a general strategy for the efficient preparation of biological scaffolds with large size HA that can be used in bone tissue engineering.

关键词： Hydroxyapatite Graphene Large size Silicon nitride nanowires Bone tissue engineering

From borophosphate to fluoroborophosphate:a rational design of fluorine-induced birefringence enhancement

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Science China Chemistry 2021年第9期64卷 1498-1503页

作者： Wenyao zhang Zhizhong zhang Wenqi Jin ruonan zhang Meng Cheng Zhihua Yang Shilie Pan CAS Key Laboratory of Functional Materials and Devices for Special Environments Xinjiang Technical Institute of Physics&ChemistryCASXinjiang Key Laboratory of Electronic Information Materials and DevicesUrumqi830011China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing100049China

The introduction of oxofluoride anion into anionic group assists to tune optical properties owing to the change of coordination,electronegativity,and according anionic ***,we proposed a rational design of new compounds by fluorine-driven structure and optical property evolution.A new borophosphate Ba_(2)BP_(3)O_(11)with the monoclinic space group P2_(1/c) has been synthesized in the sealed ***_(2)BP_(3)O_(11)exhibits a rare P-O-P bridge formation,which is the first example in alkaline-earth metal *** further substituting[BO_(4)]^(3-)with[BO_(3)F]^(4-),the first alkaline-earth metal/lead fluoroborophosphates M_(2)BP_(2)O_(8)F(M=Ba and Pb)with the same space group were *** the scissors effect of fluorine,in M_(2)BP_(2)O_(8)F(M=Ba and Pb),a BO_(3)F tetrahedron corner-sharing with three PO_(4)tetrahedra forms 1D chains along the b-axial direction,which are filled by MO_(n)(M=Ba/Pb,n=5,6,8)distorted *** first principles calculation shows that the borophosphate Ba_(2)BP_(3)O_(11)has a birefringence about 0.013@1,064 nm,while the fluoroborophosphates M_(2)BP_(2)O_(8)F(M=Ba and Pb)have the values of 0.035 and 0.043@1,064 nm,*** an apparent enhancement in birefringence is derived from synergies of the oxyfluoride and *** introduction of fluorine-containing heteroanionic groups provides a feasible strategy to design novel promising optical materials.

关键词： borophosphate fluoroborophosphates P-O-P bridges formation birefringence

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中国资源型城市碳排放特征、达峰态势及驱动因素分析

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生态经济 2025年第3期41卷 43-49,63页

作者：王宇杰段霄东薛颖张若楠蔡佳倩太原理工大学经济与管理学院山西太原030024

资源型城市是践行国家应对气候变化战略行动及实现碳达峰和碳中和目标的重要主体。论文首先对中国资源型城市的碳排放特征进行分析,接着运用Mann-Kendall趋势分析检验法对资源型城市碳达峰态势进行探究,并进一步使用STIRPAT模型和岭回... 详细信息

资源型城市是践行国家应对气候变化战略行动及实现碳达峰和碳中和目标的重要主体。论文首先对中国资源型城市的碳排放特征进行分析,接着运用Mann-Kendall趋势分析检验法对资源型城市碳达峰态势进行探究,并进一步使用STIRPAT模型和岭回归分析方法对资源型城市碳排放驱动因素进行了分析。研究发现:(1)2001—2020年,资源型城市碳排放总体呈现波动上升趋势,但不同类型城市碳排放存在较大分异,如成熟型城市碳排放增长趋势趋于平稳,衰退型城市碳排放在平稳增长后出现下降趋势。(2)截至2020年,全国资源型城市中共有20个资源型城市实现了碳达峰,占比17.54%。其中,成熟型城市数量最多,为8个;衰退型城市有6个;成长型和再生型城市的数量均为3个。(3)人口规模、经济发展水平、工业发展规模、居民消费水平、基础设施建设情况、能源消费结构均对资源型城市碳排放产生了正向影响,而产业结构对资源型城市碳排放量呈现负向影响的作用。最后,基于研究结论提出了相关建议。

关键词：资源型城市碳达峰态势驱动因素 Mann-Kendall趋势检验岭回归分析

Thermal insulating and fire-retardant Si_(3)N_(4) nanowire membranes resistant to high temperatures up to 1300℃

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Journal of Materials Science & Technology 2023年第24期155卷 82-88页

作者： Yeye Liu Leilei zhang ruonan zhang Siqi Shao Lina Sun Xinyi Wan Tiantian Wang State Key Laboratory of Solidification Processing Shaanxi Key Laboratory of Fiber Reinforced Light Composite MaterialsNorthwestern Polytechnical UniversityXi’an 710072China

Superior thermal insulating and fire-retardant ceramic membranes are urgently demanded in the aerospace,construction,and chemical engineering ***,the generic characteristics of ceramic membranes,such as brittleness,structural collapse,and crystallization-induced pulverization behavior,present a great plague to their practical ***,we report a highly flexible,mechanically stable,fire-retardant,and high-temperature-resistant ceramic membrane based on the interlocked Si_(3)N_(4) nanowires formed by the precursor pyrolysis *** Si_(3)N_(4) nanowire membrane(SNM)has excellent high-temperature resistance under alcohol lamps and butane spray *** thermal insulation with a thermal conductivity as low as 0.056 W m^(-1)K^(-1)can be attributed to the high porosity of SNM,which makes it a desirable candidate for heat insulators under harsh *** importantly,SNM exhibits thermal stability and robust mechanical properties in the range of 25 to 1300℃.The high-temperature resistance of SNM up to 1300℃is achieved by the four stages:Si3 N4 nanowires,Si_(3)N_(4)@SiO_(2) nanowires,SiO_(2) nanowires,and bead-like SiO_(2) *** heat-treated at 1300℃,the macroscopic size of SNM does not change significantly,and the interlocked structure is still ***,SNM still maintains excellent mechanical properties,with tensile strength as high as 0.26 *** work provides a facile method for fabricating excellent thermal insulating and fire-retardant ceramic membranes,showing prospective application prospects in the era of thermal insulating materials.

关键词： Silicon nitride nanowires Thermal insulation Fire-resistance High-temperature resistance

基于AnyLogic的地铁换乘站客流组织仿真与优化

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现代城市轨道交通 2025年第2期 123-129页

作者：李昌宇曹忠伟张若楠南京铁道职业技术学院运输管理学院江苏南京210031 中国铁路上海局集团有限公司徐州车务段江苏徐州221000 中国铁道科学研究院运输及经济研究所北京100081

对于客流量庞大的地铁换乘站而言,合理的客流组织是保证地铁安全运营的重要措施之一。以徐州地铁彭城广场换乘站为例,分析地铁站乘客的换乘特征及换乘方式,并结合该站的实际客流换乘现状,运用基于社会力模型的AnyLogic仿真平台对站内乘... 详细信息

对于客流量庞大的地铁换乘站而言,合理的客流组织是保证地铁安全运营的重要措施之一。以徐州地铁彭城广场换乘站为例,分析地铁站乘客的换乘特征及换乘方式,并结合该站的实际客流换乘现状,运用基于社会力模型的AnyLogic仿真平台对站内乘客换乘过程进行仿真,深度分析建筑拐角区域的客流拥堵现象。为缓解客流压力,从合理设置导流围栏的角度出发,提出针对性解决措施,并再次通过仿真模拟进行验证,结果显示,该措施可显著减少客流交叉情况,有效避免拥堵。当优化方案应用于彭城广场站后,实际拥堵情况得到明显改善,为同类型地铁换乘站客流组织提供参考。

关键词：地铁换乘站客流组织优化 Any Logic 社会力模型

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Garlic Root Biomass as Novel Biosorbents for Malachite Green Removal： Parameter Optimization, Process Kinetics and Toxicity Test

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Chemical Research in Chinese Universities 2016年第4期32卷 647-654页

作者： REN Hejun zhang ruonan WANG Qiaochu PAN Hongyu WANG Yan Key Laboratory of Groundwater Resources and Environment Ministry of Education College of Environment and Resources Jilin University Changchun 130021 P. R. China College of Plant Sciences Jilin University Changchun 130062 P. R. China

The potential of the agricultural waste garlic root to remove malachite green（MG） from aqueous solutions was evaluated. The adsorption of this dye onto garlic root was confirmed by means of Fourier transform infrared analysis（FTIR） and scanning electron microscopy（SEM）. The equilibrium data fitted well into the Langmuir model（R2〉0.99）, and the adsorption kinetics followed the pseudo-second-order equation（R2〉0.99）. The maximum ad- sorption capacities of MG onto the adsorbent were 172.41 and 232.56 mg/g with the addition of 1 and 2 g/L garlic root, respectively. The optimal conditions for MG removal were established on the basis of orthogonal experiments（OAl6 matrix）. The concentrations of both MG and garlic root significantly affected the removal efficiency. The acute toxicity test indicated that the treated MG solutions were less toxic than the parent solutions. These results suggest that garlic root is a potential low-cost adsorbent for removing dye from industrial wastewater.

关键词： Garlic root Malachite green Adsorption Toxicity test Wastewater

Simultaneously enhancing mechanical and tribological properties of carbon fiber composites by grafting SiC hexagonal nanopyramids for brake disk application

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Journal of Materials Science & Technology 2022年第26期121卷 1-8页

作者： Yao Guo Leilei zhang Qiang Song ruonan zhang Fei Zhao Wei Li Hongchao Sheng Xianghui Hou Hejun Li State Key Laboratory of Solidification Processing Shaanxi Key Laboratory of Fiber Reinforced Light Composite MaterialsNorthwestern Polytechnical UniversityXi’an 710072China Department of Materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China Faculty of Engineering The University of NottinghamUniversity ParkNottingham NG72RDUnited Kingdom

Extensive attention has been drawn to the development of carbon fiber composites for their application in brake disks due to the increasing demand for brake disks with high mechanical strength and better tribological ***,we design SiC hexagonal nanopyramids modified carbon/carbon(SiCNPsC/C)composites,in which SiCNPs are radially grafted on the carbon fibers by the combined sol-gel and carbothermal reduction method,and pyrolytic carbon(Py C)matrix is deposited on nucleation sites including carbon fibers and SiCNPs by isothermal chemical vapor infiltration(ICVI).Benefiting from the special structure,SiCNPs-C/C composites exhibit superior mechanical and frictional *** with C/C composites,SiCNPs-C/C composites have 147%,90.3%,70.6%,and 117.9%improvement in the hardness,interlaminar shear strength,and out-of-plane and in-plane compressive strength,respectively,which is attributed to the optimized fiber/matrix(F/M)interfaces bonding and the enhanced cohesion strength of Py C *** addition,the friction coefficient of SiCNPs-C/C composites increases by 25.5%,and the wear rate decreases by 38.0%.This work provides an optional design thought for the nanomaterials and enlightens the mechanical and frictional modification of composites in the field of the brakes.

关键词： SiC hexagonal nanopyramids Carbon/carbon composites Microstructure Mechanical properties Tribological properties