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Geomorphic change in Dingzi Bay, East China since the 1950s： impacts of human activity and fluvial input

Frontiers of Earth Science 2017年第2期11卷 385-396页

作者： qing TIAN qing wang Yalong LIU Oceanic Modeling and Observation Laboratory School of Marine Science Nanjing University of Information Science and Technology Nanjing 210044 China Coast Institute Ludong University Yantai 264025 China Yantai Marine Environmental Monitoring Center Station State Oceanic Administration Yantai 264000 China

This study examines the geomorphic evolution of Dingzi Bay, East China in response to human activity and variations in fluvial input since the 1950s. The analysis is based on data from multiple mathematical methods, along with information obtained from Remote Sensing, Geographic Information System and Global Position System technology. The results show that the annual runoff and sediment load discharged into Dingzi Bay display significant decreasing trends overall, and marked downward steps were observed in 1966 and 1980. Around 60%-80% of the decline is attributed to decreasing precipitation in the Wulong River Basin. The landform types in Dingzi Bay have changed significantly since the 1950s, especially over the period between 1981 and 1995. Large areas of tidal fiats, swamp, salt fields, and paddy fields have been reclaimed, and aquaculture ponds have been constructed. Consequently, the patterns of erosion and deposition in the bay have changed substantially. Despite a reduction in sediment input of 65.68% after 1966, low rates of sediment deposition continued in the bay. However, deposition rates changed significantly after 1981 owing to large-scale development in the bay, with a net depositional area approximately 10 times larger than that during 1961-1981. This geomorphic evolution stabilized following the termination of large-scale human activity in the bay after 1995. Overall, Dingzi Bay has shown a tendency towards silting-up during 1952-2010, with the bay head migrating seaward, the number of channels in the tidal creek system decreasing, and the tidal inlet becoming narrower and shorter. In conclusion, large- scale development and human activity in Dingzi Bay have controlled the geomorphic evolution of the bay since the 1950s.

关键词： sediment load runoff human activity,geomorphic evolution Dingzi Bay

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Experimental realization of chiral Landau levels in two-dimensional Dirac cone systems with inhomogeneous effective mass

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Light(Science & Applications) 2023年第8期12卷 1616-1622页

作者： Hongwei Jia Mudi wang Shaojie Ma ruo-Yang Zhang Jing Hu Dongyang wang Che Ting Chan Department of Physics the Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina Institute for Advanced Study the Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina Department of Physics University of Hong KongHong KongChina

Chiral zeroth Landau levels are topologically protected bulk *** particle physics and condensed matter physics,the chiral zeroth Landau level plays a significant role in breaking chiral symmetry and gives rise to the chiral *** experimental works on such chiral Landau levels are mainly based on three-dimensional Weyl degeneracies coupled with axial magnetic *** realizations using two-dimensional Dirac point systems,being more promising for future applications,were never experimentally realized *** we propose an experimental scheme for realizing chiral Landau levels in a two-dimensional photonic *** introducing an inhomogeneous effective mass through breaking local parity-inversion symmetries,a synthetic in-plane magnetic field is generated and coupled with the Dirac ***,the zeroth-order chiral Landau levels can be induced,and the one-way propagation characteristics are experimentally *** addition,the robust transport of the chiral zeroth mode against defects in the system is also experimentally *** system provides a new pathway for the realization of chiral Landau levels in two-dimensional Dirac cone systems,and may potentially be applied in device designs utilizing the chiral response and transport robustness.

关键词： chiral Landau realization

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Effect of Rheological Behavior of Particle-Water Suspensions on Properties of Gunned Refractory for Blast Furnace

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Journal of Iron and Steel Research International 2006年第1期13卷 10-13页

作者： CAO Feng MENG qing-min LONG Shi-gang SUN Jia-lin HONG Yan-ruo School of Metallurgy and Materials Anhui University of Technology Ma＇anshan 243002 Anhui China School of Metallurgical and Ecological Engineering University of Science and Technology Beijing Beijing 100083 China

Study on rheological properties of gunned refractory is an effective way to optimize the quality of repaired layer and gunning operation. The fluidity of refractory was quantitatively evaluated as well as the rheological behavior of refractory particle-water suspensions. The relationship between the fluidity of refractory particle-water suspension and that of gunned refractory, and the relationship between the fluidity and adhesion ability of gunned refractory were studied. The experiments were carried out with a special rheometer and gunning machine. The results show that there is strong influence of some parameters on the rheological behavior of gunned refractory and gunning process. Interactions between particles and water that lead to the formation of gelatinous structures in this suspension are discussed.

关键词： fluidity gunned refractory rheological behavior

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Derivation of the Bosonic Part of the Electroweak Chiral Lagrangian from a General Underlying Technicolor Theory

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Communications in Theoretical Physics 2001年第10期36卷 417-426页

作者： wang Zhi-Min wang qing Department of Physics Tsinghua University Beijing 100084 China Department of Physics Tsinghua University Beijing 100084 ChinaCCAST World Laboratory P.O. Box 8730 Beijing 100080 China Institute of Theoretical Physics Academia Sinica Beijing 100080 China

Bosonic part of SU(2)L U(1)Y effective chiral Lagrangian for electroweak symmetry breaking is derived from an underlying technicolor theory with no approximation. The underlying theory is assumed to be the most general gauge theory without fundamental scalars. A condensate is required to exist in the theory which breaks SU(2)L U(1)Y dynamically to U(1)em and the anomaly of the theory caused by gauge interaction must be cancelled. The formulation offers general definitions in terms of underlying theory for the low energy constants in effective chiral Lagrangian.

关键词： chiral Lagrangian, electroweak symmetry, technicolor, derivation

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Comments on‘Dietary intervention preservesβcell function in mice through CTCF-mediated transcriptional reprogramming’

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Journal of Molecular Cell Biology 2022年第7期14卷 76-77页

作者： ruo-Ran wang Hongxing Fu Jingya Li Zhuo-Xian Meng School of Pharmaceutical Science and Technology Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China State Key Laboratory of Drug Research the National Center for Drug ScreeningShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Department of Pathology and Pathophysiology and Department of Cardiology of the Second Affiliated Hospital Zhejiang University School of MedicineHangzhou 310058China Department of Pharmacy Shulan(Hangzhou)Hospital Affiliated to Zhejiang Shuren University Shulan International Medical CollegeHangzhou 310000China

Type 2 diabetes(T2D)has become a common chronic disease ***βcell dysfunction,together with insulin resistance,is among the main causes for the pathogenesis of ***,the dynamic changes in the number and function ofβcells and the molecular mechanism of irreversible damage in the pathogenesis of T2D are still unclear.A thorough analysis of the mechanism underlyingβcell dysfunction will provide a theoretical basis and molecular targets for the development of new and more effective individualized therapies for diabetes.

关键词： βcell pathogenesis diabetes

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Combined hamartoma of the retina and retinal pigment epithelium:A case report

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World Journal of Clinical Cases 2023年第8期11卷 1788-1793页

作者： qing Ren Ning Han Rui Zhang ruo-Fan Chen Peng Yu Department of Ophthalmology The Second Hospital of Jilin UniversityChangchun 130022Jilin ProvinceChina

BACKGROUND Combined hamartoma of the retina and retinal pigment epithelium(CHRRPE)is a rare congenital benign tumor which is commonly *** CHRRPE comprises slightly raised lesions at the posterior pole,with proliferation membrane often leading to vascular *** severe cases,macular edema,macular hole,retinal detachment or vitreous hemorrhage may *** with atypical clinical manifestations are prone to misdiagnosis by inexperienced *** SUMMARY A 33-year-old man reported onset of right eye blurred vision for one week *** segment and intraocular pressure were normal in both *** eye fundus photography was *** eye ophthalmoscopy showed vitreous hemorrhage and off-white raised retinal lesions below the optic *** membranes on the lesion surfaces resulted in superficial retinal detachment and tortuosity and occlusion of peripheral blood vessels.A horseshoe-like tear in the temporal periphery was surrounded by retinal *** coherence tomography revealed retinal thickening at the focal site with structural disturbance indicated by high *** eye ultrasound showed retinal thickening at the lesion,stretching and uplifting of the proliferative membrane,with moderately patchy echo at the optic disc *** and antibodies were detected in vitreous fluids during the operation to rule out other *** fluorescein angiography(FFA)at postoperative follow-up led to final diagnosis of *** FFA is helpful in diagnosing retinal and retinal pigment epithelial combined *** addition,other cytokine and etiological tests facilitate further differential diagnosis to rule out other suspected diseases.

关键词： Combined hamartoma of the retina and retinal pigment epithelium Ocular toxoplasmosis Fundus fluorescein angiography Vitreous hemorrhage Retinal tears Case report

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Studies on the Quantitative Structure-activity Relationship of Toxicity of Chlorophenol Serial Compounds in the ab initio Methods and Substitutive Position of Chlorine Atom (N_(PCS))

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Chinese Journal of Structural Chemistry 2007年第8期26卷 933-938页

作者： ZHENG qing wang Lian-Sheng Chemistry ＆ Bioengineering College Yancheng Institute of Technology Yancheng Jiangsu 224003 China School of the Environment Nanjing University Nanjing Jiangsu 210093 China

20 Quantum chemical parameters of chlorophenol compounds were fully optimized by using B3LYP method on both 6-31G^＊ and 6-311G^＊ basis sets. These structural parameters are taken as theoretical descriptors, and the experimental data of 20 compounds＇ aquatic photogen toxicity（-lgEC50） are used to perform stepwise regression in order to obtain two predicted -lgEC50 correlation models whose correlation coefficients R^2 are respectively 0.9186 and 0.9567. In addition, parameters of chlorine atom＇s substitutive positions and their correlations （NPCs） are taken as descriptors to obtain another predicted -lgEC50 model with the correlation coefficient R2 of 0.9444. Correlation degree of each independent variable in the three models is verified by using variance inflation factors （VIF） and t value. In the cross-validation method, cross-validation coefficients q^2 of 3 models are respectively 0.8748, 0.9119 and 0.8993, which indicates that the relativity and prediction ability of this model are superior to those of the model obtained by topological and BLYP methods.

关键词： chlorophenol toxicity (-lgEC50) linear dissolving energy theory density functional theory (DFT) substitutive position of chlorine atom (NPCS) QSAR

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Some nonlinear parameters of PP intervals of pulse main peaks

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第8期8卷 1256-1262页

作者： HAN qing-peng wang Ping School of Biomedical Engineering and Instrument Science Zhejiang University Hangzhou 310027 China

The PP intervals of pulse main peaks from healthy and unhealthy people(arrhythmia) have different nonlinear char-acteristics. In this paper,the extraction of PP intervals of pulse main peaks is achieved by picking up P peaks of pulse wave with wavelet transform. Furthermore,several nonlinear parameters(correlative dimensions,maximum Lyapunov exponents,com-plexity and approximate entropy) of the PP intervals of pulse main peaks extracted from normal and unhealthy pulse signals are calculated,with the results showing that these nonlinear parameters calculated from the main wave interval signals are helpful for analyzing human's health state and diagnosing heart diseases.

关键词： PP intervals of pulse main peaks Phase space reconstruction Correlative dimension Lyapunov exponent Complexity Approximate entropy

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Thymosin Beta-4 Recombinant Adeno-associated Virus Enhances Human Nucleus Pulposus Cell Proliferation and Reduces Cell Apoptosis and Senescence

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Chinese Medical Journal 2015年第11期128卷 1529-1535页

作者： Yuan-Yi wang qing-San Zhu Yi-Wei wang ruo-Feng Yin Department of Spine Surgery The First Hospital of Jilin University Changchun Jilin 130021 China Department of OrthoPedics China-Japan UnionHospital of Jilin University C-hangchun Jilin 130021 China Department of Pathophysiology Jiangsu Jiankang Vocational College Nanjing Jiangsu 210029 China

Background： Thymosin beta-4 （TB-4） is considered key roles in tissue development, maintenance and pathological processes. The study aimed to prove TB-4 positive biological function on nucleus pulposus （NP） cell apoptosis and slowing the process of cell aging while increasing the cell proliferation. Methods： TB-4 recombinant adeno-associated virus （AAV） was constructed and induced to human NP cells. Cell of same group were cultured without gene modification as controlled group. Proliferation capacity and cell apoptosis were observed during 6 passages of the cells. Morphology and expression of the TB-4 gene were documented as parameter of cell activity during cell passage. Results： NP cells with TB-4 transfection has normal TB-4 expression and exocytosis. NP cells with TB-4 transfection performed significantly higher cell activity than that at the control group in each generation. TB-4 recombinant AAV-transfected human NP cells also show slower cell aging, lower cell apoptosis and higher cell proliferation than control group. Conclusions： TB-4 can prevent NP cell apoptosis, slow NP cell aging and promote NP cell proliferation. AAV transfection technique was able to highly and stably express TB-4 in human NP cells, which may provide a new pathway for innovation in the treatment of intervertebral disc degenerative diseases.

关键词： Biological Treatment Cell Aging Degeneration of Intervertebral Disc Thymosin Beta-4

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Grain proteomic analysis reveals central stress responsive proteins caused by wheat-Haynaldia villosa 6VS/6AL translocation

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Journal of Integrative Agriculture 2020年第11期19卷 2628-2642页

作者： ZOU Rong WU Ji-su wang ruo-mei YAN Yue-ming College of Life Science Capital Normal UniversityBeijing 100048P.R.China Hubei Collaborative Innovation Center for Grain Industry(HCICGI) Yangtze UniversityJingzhou 434023P.R.China

Haynaldia villosa(2n=14,VV),a wild grass of the subtribe Triticeae,serves as potential gene resources for wheat genetic *** this study,the proteome characterization during grain development of Yangmai 5 and Yangmai *** 6VS/6AL translocation line was investigated by a comparative proteomic ***-dimensional electrophoresis identified 81 differentially accumulated proteins(DAPs)during five grain developmental stages in *** translocation *** proteins were mainly involved in stress defense,storage protein,energy metabolism,protein metabolism and folding,carbon metabolism,nitrogen metabolism,and starch *** particular,6VS/6AL translocation led to significant upregulation of 36 DAPs and specific expression of 11 DAPs such as chitinase,thaumatin-like proteins,glutathione transferase,α-amylase inhibitor,heat shock proteins,and betaine aldehyde *** proteins mainly involved in biotic and abiotic stress *** analysis found that the upstream 1500 promoter regions of these stress-responsive DAP genes contained multiple high-frequency cis-acting elements related to stress defense such as abscisic acid response element ABRE,methyl jasmonate(MeJA)-response element TGACG-motif and CGTCA-motif involved in oxidative stress and antioxidant response element(ARE).RNA-seq and RT-qPCR analyses revealed the high expression of these stress-defensive DAP genes in the developing grains,particularly at the early-middle grain filling *** results demonstrated that 6VS chromosome of *** contains abundant stress-defensive proteins that have potential values for wheat genetic improvement.

关键词： 6VS/6AL translocation grain development proteome DAPs cis-acting elements adverse defense

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