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Chinese Physics B 2022年第1期31卷 101-106页

作者： runrun hao Kun Zhang Yinggang Li Qiang Cao Xueying Zhang Dapeng Zhu Weisheng Zhao Fert Beijing Institute MIIT Key Laboratory of SpintronicsSchool of Integrated Circuit Science and EngineeringBeihang UniversityBeijing 100191China Beihang-Goertek Joint Microelectronics Institute Qingdao Research InstituteBeihang UniversityQingdao 266000China Spintronics Institute University of JinanJinan 250022China Truth Instruments Co.Ltd. Qingdao 266000China

Effective probing current-induced magnetization switching is highly required in the study of emerging spin-orbit torque(SOT)***,the measurement of in-plane magnetization switching typically relies on the giant/tunneling magnetoresistance measurement in a spin valve structure calling for complicated fabrication process,or the non-electric approach of Kerr imaging ***,we present a reliable and convenient method to electrically probe the SOT-induced in-plane magnetization switching in a simple Hall bar device through analyzing the MR signal modified by a magnetic *** this case,the symmetry of MR is broken,resulting in a resistance difference for opposite magnetization ***,the feasibility of our method is widely evidenced in heavy metal/ferromagnet(Pt/Ni_(20)Fe_(80) and W/Co_(20)Fe_(60)B_(20))and the topological insulator/ferromagnet(Bi_(2)Se_(3)/Ni_(20)Fe_(80)).Our work simplifies the characterization process of the in-plane magnetization switching,which can promote the development of SOT-based devices.

关键词： magnetoresistance in-plane magnetization switching electrical detection

Magnetic coupling governed pinning directions in magnetic tunnel junctions under magnetic field annealing with zero magnetic field cooling

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Science China(Information Sciences) 2023年第4期66卷 305-306页

作者： Weibin CHEN Shaohua YAN Zhiqiang CAO Shiyang LU Xiaonan Zhao runrun hao Zitong ZHOU Zhi LI Kun ZHANG Shishen YAN Qunwen LENG School of Physics State Key Laboratory of Crystal Materials Shandong University Fert Beijing Institute MIIT Key Laboratory of Spintronics School of Integrated Circuit Science and Engineering Beihang University

With the rapid development of emerging concepts, such as the Internet of things and big data, the use of various magnetoresistance(MR) sensors, especially tunneling MR(TMR) in magnetic tunnel junctions(MTJs), for information perception is considered the critical first step. A typical topic in this field is the construction of a Wheatstone bridge structure to restrain the temperature drift and amplify the magnetic response signal.

关键词： Magnetic fields

Spin-independent transparency of pure spin current at normal/ferromagnetic metal interface

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Chinese Physics B 2018年第3期27卷 401-404页

作者： runrun hao Hai Zhong Yun Kang Yufei Tian Shishen Yan Guolei Liu Guangbing Han Shuyun Yu Liangmo Mei Shishou Kang School of Physics and State Key Laboratory of Crystal Materials Shandong University Jinan 250100. China

The spin transparency at the normal/ferromagnetic metal （NM/FM） interface was studied in PffYIG/Cu/FM multilayers. The spin current generated by the spin Hall effect （SHE） in Pt flows into Cu/FM due to magnetic insulator YIG blocking charge current and transmitting spin current via the magnon current. Therefore, the nonlocal voltage induced by an inverse spin Hall effect （ISHE） in FM can be detected. With the magnetization of FM parallel or antiparallel to the spin polarization of pure spin currents （σsc）, the spin-independent nonlocal voltage is induced. This indicates that the spin transparency at the Cu/FM interface is spin-independent, which demonstrates that the influence of spin-dependent electro-chemical potential due to spin accumulation on the interfacial spin transparency is negligible. Furthermore, a larger spin Hall angle of Fe20Ni80 （Py） than that of Ni is obtained from the nonlocal voltage measurements.

关键词： spin transparency spin current magnetic insulator inverse Hall effect

Magnetization-direction-dependent inverse spin Hall effect observed in IrMn/NiFe/Cu/YIG multilayer structure

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Chinese Physics B 2019年第3期28卷 333-336页

作者： runrun hao Ruxue Zang Tie Zhou Shishou Kang Shishen Yan Guolei Liu Guangbing Han Shuyun Yu Liangmo Mei School of Physics and State Key Laboratory of Crystal Materials Shandong University

The magnetization-direction-dependent inverse spin Hall effect(ISHE) has been observed in NiFe film during spin Seebeck measurement in IrMn/NiFe/Cu/yttrium iron garnet(YIG) multilayer structure, where the YIG and NiFe layers act as the spin injector and spin current detector, respectively. By using the NiFe/IrMn exchange bias structure, the magnetization direction of YIG(MYIG) can be rotated with respect to that of NiFe(MNiFe) with a small magnetic field, thus allowing us to observe the magnetization-direction-dependent inverse spin Hall effect voltage in NiFe layer. Compared with the situation that polarization direction of spin current(σs) is perpendicular to MNiFe, the spin Seebeck voltage is about 30% larger than that when σs and MNiFe are parallel to each other. This phenomenon may originate from either or both of stronger interface or bulk scattering to spin current when σs and MNiFe are perpendicular to each other. Our work provides a way to control the voltage induced by ISHE in ferromagnets.

关键词： spin current magnetic insulator inverse Hall effect

High repetition granular Co/Pt multilayers with improved perpendicular remanent magnetization for high-density magnetic recording

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Chinese Physics B 2023年第2期32卷 405-410页

作者：李智张昆杜奥张洪超陈伟斌徐宁郝润润颜世申赵巍胜冷群文 Fert Beijing Research Institute MIIT Key Laboratory of Spintronics School of Integrated Circuit Science and EngineeringBeihang UniversityBeijing 100191China Beihang–Goertek Joint Microelectronics Institute Qingdao Research Institute Beihang UniversityQingdao 266101China School of Physics State Key Laboratory of Crystal Materials Shandong UniversityJinan 250100China

Thanks to the strong perpendicular magnetic anisotropy(PMA), excellent processing compatibility as well as novel spintronic phenomenon, Co/Pt multilayers have been attracting massive attention and widely used in magnetic ***, reversed magnetic domains come into being with the increasing layer repetition ‘N’ to reduce magneto-static energy, resulting in the remarkable diminishment of the remanent magnetization(Mr). As a result, the product of Mrand thickness(i.e., the remanent moment-thickness product, Mrt), a key parameter in magnetic recording for reliable data storing and reading, also decreases dramatically. To overcome this issue, we deposit an ultra-thick granular [Co/Pt]80multilayer with a total thickness of 68 nm on granular SiNxbuffer layer. The Mrt value, Mrto saturation magnetization(Ms) ratio as well as out of plane(OOP) coercivity(Hcoop) are high up to 2.97 memu/cm^(2), 67%, and 1940 Oe(1 Oe = 79.5775 A·m^(-1)),respectively, which is remarkably improved compared with that of continuous [Co/Pt]80multilayers. That is because large amounts of grain boundaries in the granular multilayers can efficiently impede the propagation and expansion of reversed magnetic domains, which is verified by experimental investigations and micromagnetic simulation results. The simulation results also indicate that the value of Mrt, Mr/Msratio, and Hcoopcan be further improved through optimizing the granule size, which can be experimentally realized by manipulating the process parameter of SiNxbuffer layer. This work provides an alternative solution for achieving high Mrt value in ultra-thick Co/Pt multilayers, which is of unneglectable potential in applications of high-density magnetic recording.

关键词： granular Co/Pt multilayers perpendicular magnetic anisotropy remanent moment-thickness product magnetic recording

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医学院校基础-临床桥梁学科教学现状与改革

科教导刊 2021年第32期 136-138页

作者：何晓璞郝润润庄帅帅华杰南京医科大学第一附属医院(江苏省人民医院) 江苏南京210029 南京医科大学第一临床医学院江苏南京211166 溧阳市人民医院消化科江苏溧阳213300

基础-临床桥梁学科是医学生学习基础医学与临床医学之间的衔接阶段,这类学科具有相同的特征即较强的理论性与实践性。就现况而言,这类桥梁学科在教学上存在有学科设置、教师培训、教学效果、考核内容等方面的不足。本文将结合实际阐述... 详细信息

基础-临床桥梁学科是医学生学习基础医学与临床医学之间的衔接阶段,这类学科具有相同的特征即较强的理论性与实践性。就现况而言,这类桥梁学科在教学上存在有学科设置、教师培训、教学效果、考核内容等方面的不足。本文将结合实际阐述桥梁学科的教学现况并提出教学改革的措施,为指导基础-临床桥梁学科的教学实践提供新的思路。

关键词：教学改革桥梁学科医学教学

橘红素经PI3K/Akt/mTOR信号通路调控胃癌细胞BGC-823和SGC-7901的增殖和凋亡

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胃肠病学和肝病学杂志 2024年第2期33卷 162-166,170页

作者：庄帅帅郝润润龚旖纯黄磊蒋魏华杰何晓璞南京医科大学第一附属医院消化科江苏南京210000 南京医科大学第一临床医学院溧阳市人民医院消化内科

目的探讨橘红素对胃癌细胞BGC-823和SGC-7901的自噬作用及其机制。方法不同浓度橘红素(7.5、15、30、60、120μmol/L)处理两株细胞后,CCK-8法检测其吸光度值,计算细胞增殖抑制率;流式细胞仪检测细胞凋亡水平;用60μmol/L浓度的橘红素处... 详细信息

目的探讨橘红素对胃癌细胞BGC-823和SGC-7901的自噬作用及其机制。方法不同浓度橘红素(7.5、15、30、60、120μmol/L)处理两株细胞后,CCK-8法检测其吸光度值,计算细胞增殖抑制率;流式细胞仪检测细胞凋亡水平;用60μmol/L浓度的橘红素处理后通过细胞划痕法检测两种细胞迁移能力;Western blotting法检测自噬相关蛋白p62、凋亡蛋白Bax、Bcl-2及PI3K/Akt/mTOR信号通路相关蛋白表达的影响。结果与对照组相比,橘红素处理组增殖、迁移能力显著下降(P<0.01),细胞凋亡数增加,自噬蛋白p62的表达浓度依赖性升高(P<0.05),凋亡蛋白Bax表达增加(P<0.05),Bcl-2表达下降(P<0.05),磷酸化的p-Akt和p-mTOR的表达水平显著降低(P<0.05)。结论橘红素可通过抑制PI3K/Akt/mTOR信号通路调控SGC-7901和BGC-823细胞的增殖和凋亡,并可抑制其自噬。

关键词：橘红素胃癌自噬增殖凋亡 PI3K/Akt/mTOR信号通路

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淮河流域近500年洪旱事件演变特征分析

水科学进展 2014年第4期25卷 503-510页

作者：杨传国陈喜张润润胡琪余钟波郝振纯林朝晖河海大学水文水资源与水利工程科学国家重点实验室河海大学水文水资源学院 School of Natural Resources and Department of Earth and Atmospheric Sciences University of Nebraska-Lincoln LincolnNE68588-0987USA 中国科学院大气物理研究所

为了认识淮河流域过去500年洪旱事件发生规律并鉴别当前的洪旱情势，收集并对比分析了流域实测降雨资料、重建历史雨季降雨资料、历史旱涝等级资料、历史洪旱文献记录和历史调查洪水资料等多源洪旱灾害数据。以重建历史雨季降雨资料和... 详细信息

为了认识淮河流域过去500年洪旱事件发生规律并鉴别当前的洪旱情势，收集并对比分析了流域实测降雨资料、重建历史雨季降雨资料、历史旱涝等级资料、历史洪旱文献记录和历史调查洪水资料等多源洪旱灾害数据。以重建历史雨季降雨资料和历史旱涝等级资料为主要依据，通过滑动平均、频率计算、小波分析和突变检验等方法，分析流域过去500年洪水干旱时空分布特征和演变规律。结果表明，17世纪淮河流域洪旱灾害最严重，但20世纪极端洪旱事件发生频次最多。淮河流域洪旱事件存在40年左右的稳定长周期，主周期从18世纪的15～20年逐渐减少到19世纪的5年周期，近20年来出现2～3年的主周期，洪旱灾害事件呈增加趋势，流域社会经济发展面临着严峻的洪旱灾害威胁。

关键词：洪水干旱重建历史降雨演变特征淮河流域

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基于氮化镓的导模共振滤波器仿真分析

光通信研究 2014年第6期6期(23)卷 55-58页

作者：赵昊诸波胡芳仁魏润润南京邮电大学光电工程学院南京210023

根据严格耦合波理论和等效介质理论，提出了针对C波段、基于半导体材料氮化镓的亚波长导模共振滤波器结构及设计方法。详细探讨了在强调制光栅的高占空比作用下，光栅周期和入射波角度对滤波器反射谱共振波长的影响。在保持滤波效果为... 详细信息

根据严格耦合波理论和等效介质理论，提出了针对C波段、基于半导体材料氮化镓的亚波长导模共振滤波器结构及设计方法。详细探讨了在强调制光栅的高占空比作用下，光栅周期和入射波角度对滤波器反射谱共振波长的影响。在保持滤波效果为高衍射率（共振波长峰值反射率达到99.5%以上）、低旁带和窄线宽的条件下，利用其对入射波角度的敏感性，结合仿真数值提出了一种通过 MEMS（微机电系统）平面反射镜调谐入射角角度（0-4.07°），从而线性地控制共振波长输出（调谐范围为36 nm），实现峰值半宽高低于0.8 nm的C波段可调滤波器。

关键词：导模共振氮化镓滤波器微机电系统

溶菌酶的修饰、功能特性及其在食品保鲜中的应用研究进展

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食品科学 2019年第21期40卷 334-342页

作者：孙浩石玉刚朱陈敏张润润陈建设 Rammile ETTELAIE 浙江工商大学食品与生物工程学院浙江杭州310018 利兹大学食品科学与营养学院英国利兹LS29JT

溶菌酶是一种自然界中广泛存在的天然防腐剂,能选择性溶解目标微生物的细胞壁而使其失去生理活性,已被广泛应用于食品工业。天然溶菌酶主要抑制革兰氏阳性菌的生长,而对革兰氏阴性菌几乎不起作用或作用较弱;因此,对溶菌酶实施分子结构调... 详细信息

溶菌酶是一种自然界中广泛存在的天然防腐剂,能选择性溶解目标微生物的细胞壁而使其失去生理活性,已被广泛应用于食品工业。天然溶菌酶主要抑制革兰氏阳性菌的生长,而对革兰氏阴性菌几乎不起作用或作用较弱;因此,对溶菌酶实施分子结构调整,扩展其抑菌谱具有十分重要的意义。本文重点将近年来国内外已报道的各类溶菌酶增效技术(物理、化学与生物改性技术等,特别是辅以纳米制备技术)、改性后溶菌酶对有害微生物的抑制效果及作用机制和改性后溶菌酶的其他功能特性变化(活性、稳定性、乳化性等)等做了详细综述;同时介绍了改性溶菌酶在食品贮藏与保鲜等领域中的应用情况,并对溶菌酶的分子改性策略、溶菌酶与纳米及材料科学结合应用的潜力进行了展望。

关键词：溶菌酶改性抗菌革兰氏阴性菌纳米技术