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A good prognostic predictor for liver transplantation recipients with benign end-stage liver cirrhosis

Hepatobiliary & Pancreatic Diseases International 2017年第2期16卷 164-168页

作者： Qiang Wei Rahmeet Singh Nemdharry run-zhou zhuang Jie Li Qi Ling Jian Wu Tian Shen Lin zhou Hai-Yang Xie Min Zhang Xiao Xu Shu-Sen Zheng Key Lab of Combined Multi-Organ Transplantation Ministry of Public Health Division of Hepatobiliary and Pancreatic Surgery Department of Surgery First Affiliated Hospital Zhejiang University School of Medicine Hangzhou 310003 China Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases Hangzhou 310003 China

BACKGROUND： Post-transplant model for predicting mortality（PMPM, calculated as-5.359＋1.988×ln（serum creatinine [mg/d L]）＋1.089×ln（total bilirubin [mg/d L]）） score has been proved to be a simple and accurate model for predicting the prognosis after liver transplantation（LT） in a single center study. Here we aim to verify this model in a large cohort of ***： A total of 2727 patients undergoing LT with endstage liver cirrhosis from January 2003 to December 2010 were included in this retrospective study. Data were collected from the China Liver Transplant Registry（CLTR）. PMPM score was calculated at 24-h and 7-d following LT. According to the PMPM score at 24-h, all patients were divided into the low-risk group（PMPM score ≤-1.4, n=2509） and the high-risk group（PMPM score 〉-1.4, n=218）. The area under receiver operator characteristic curve（AUROC） was calculated for evaluating the prognostic ***： The 1-, 3-, and 5-year patient survival rates in the low-risk group were significantly higher than those in the high-risk group（90.23%, 88.01%, and 86.03% vs 63.16%, 59.62%, and 56.43%, respectively, P〈0.001）. In the high-risk group, 131 patients had a decreased PMPM score（≤-1.4） at 7-d, and their cumulative survival rate was significantly higher than the other 87 patients with sustained high PMPM score（〉-1.4）（P〈0.001）. For predicting 3-month mortality, PMPM score showed a much higher AUROC than post-transplant MELD score（P〈0.05）.CONCLUSION： PMPM score is a simple and effective tool to predict short-term mortality after liver transplantation in patients with benign liver diseases, and an indicator for prompt salvaging treatment as well.

关键词： cirrhosis liver transplantation post-transplant model for predicting mortality score prognosis

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Selective synthesis and physical properties of a bismacrocycle:Cycloparaphenylene-pillar[5]arene

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Chinese Chemical Letters 2024年第3期35卷 273-276页

作者： Yu zhou Guilin zhuang Pingwu Du Key Laboratory of Precision and Intelligent Chemistry Hefei National Laboratory for Physical Sciences at the MicroscaleCAS Key Laboratory of Materials for Energy ConversionDepartment of Materials Science and EngineeringUniversity of Science and Technology of ChinaHefei 230026China College of Chemical Engineering Zhejiang University of TechnologyHangzhou 310032China

Macrocyclic materials have attracted much attention due to their particular chemical and physical *** we report the precise synthesis and characterization of a new bismacrocycle structure base on cycloparaphenylene(CPP)and pillar[5]arene,named cycloparaphenylene-pillar[5]arenes(CPPn[5]).The bismacrocycle was fully characterized by NMR and *** photophysical properties of CPPn[5]were investigated by UV–vis,and the maximum absorption peak was located at 331 nm,which was consistent with density functional theory(DFT)*** fluorescence spectrum was further studied and the emission peak was maximized at 458 *** computational results indicate the strain energy of CPPn[5]is 27.80 kcal/mol and the HOMO-LUMO gap is 3.39 eV Notably,CPPn[5]showed interesting supramolecular properties.

关键词： Pillararene Cycloparaphenylene Bismacrocycles Supramolecular chemistry

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Security-Enhanced Directional Modulation Based on Two-Dimensional M-WFRFT

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China Communications 2024年第5期21卷 229-248页

作者： zhou zhuang Luo Junshan Wang Shilian Xia Guojiang School of Electronic Science National University of Defense TechnologyChangsha 410073China Beijing Institute of Astronautical Systems Engineering Beijing 100076China

Directional modulation(DM)is one of the most promising secure communication ***,when the eavesdropper is co-located with the legitimate receiver,the conventional DM has the disadvantages of weak anti-scanning capability,anti-deciphering capability,and low secrecy *** response to these problems,we propose a twodimensional multi-term weighted fractional Fourier transform aided DM scheme,in which the legitimate receiver and the transmitter use different transform terms and transform orders to encrypt and decrypt the confidential *** order to further lower the probability of being deciphered by an eavesdropper,we use the subblock partition method to convert the one-dimensional modulated signal vector into a twodimensional signal matrix,increasing the confusion of the useful *** results demonstrate that the proposed DM scheme not only provides stronger anti-deciphering and anti-scanning capabilities but also improves the secrecy rate performance of the system.

关键词： bit error rate directional modulation phased array secrecy rate weighted fractional Fourier transform

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Enhancement of liquid-liquid micromixing performance in curved capillary microreactor by generation of Dean vortices

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Chinese Journal of Chemical Engineering 2024年第4期68卷 76-82页

作者： Shaoyun Wu zhuang Ma Zichi Yang Suying Zhao Caijin zhou Huidong Zheng Fujian Engineering Research Center of Advanced Manufacturing Technology for Fine Chemicals College of Chemical EngineeringFuzhou UniversityFuzhou 350108China Qingyuan Innovation Laboratory Quanzhou362114China

Micromixing efficiency is an important parameter for evaluating the multiphase mass transfer performance and reaction efficiency of *** this work,the novel curved capillary reactor with different shapes was designed to generate Dean flow,which was used to enhance the liquid-liquid micromixing *** Villermaux-Dushman probe reaction was employed to characterize the micromixing performance in different curved capillary *** effects of experiment parameters such as liquid flow rate,inner diameter,tube length,and curve diameter on micromixing performance were systematically *** the optimal conditions,the minimum value of the segmentation factor XS was *** was worth noting that at the low Reynolds number(Re<30),the change of curved shape on the capillary microreactor can significantly improve the micromixing performance with XS reduced by 37.5%.Further,the correlations of segment index XS with dimensionless factor such as Reynolds number or Dean number were developed,which can be used to predict the liquid-liquid micromixing performance in capillary microreactors.

关键词： Microreactor Process intensification Micromixing performance Dean flow

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Transient stimulated Raman scattering spectroscopy and imaging

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Light(Science & Applications) 2024年第4期13卷 654-663页

作者： Qiaozhi Yu Zhengjian Yao Jiaqi zhou Wenhao Yu Chenjie zhuang Yafeng Qi Hanqing Xiong National Biomedical Imaging Center College of Future TechnologyPeking UniversityBeijing 100871China Biomedical Engineering Department College of Future TechnologyPeking UniversityBeijing 100871China

Stimulated Raman scattering(SRS)has been developed as an essential quantitative contrast for chemical imaging in recent ***,while spectral lines near the natural linewidth limit can be routinely achieved by state-of-the-art spontaneous Raman microscopes,spectral broadening is inevitable for current mainstream SRS imaging *** is because those SRS signals are all measured in the frequency *** is a compromise between sensitivity and spectral resolution:as the nonlinear process benefits from pulsed excitations,the fundamental time-energy uncertainty limits the spectral ***,the spectral range and acquisition speed are mutually *** we report transient stimulated Raman scattering(T-SRS),an alternative time-domain strategy that bypasses all these fundamental conjugations.T-SRS is achieved by quantum coherence manipulation:we encode the vibrational oscillations in the stimulated Raman loss(SRL)signal by femtosecond pulse-pair sequence excited vibrational wave packet *** Raman spectrum was then achieved by Fourier transform of the time-domain SRL *** all Raman modes are impulsively and simultaneously excited,T-SRS features the natural-linewidth-limit spectral line shapes,laser-bandwidth-determined spectral range,and improved ***~150-fs laser pulses,we boost the sensitivity of typical Raman modes to the sub-mM *** all-plane-mirror high-speed time-delay scanning,we further demonstrated hyperspectral SRS imaging of live-cell metabolism and high-density multiplexed imaging with the natural-linewidth-limit spectral resolution.T-SRS shall find valuable applications for advanced Raman imaging.

关键词： scattering excited mutually

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Response of nitrogen-cycling key functional genes and microbial communities in paddy soils to microplastics combined with antibiotics

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Science China Technological Sciences 2024年第10期67卷 3132-3135页

作者： LIN LiJun YANG GuiQin QUAN XiaoYun zhou ZhuoYi CHEN XiaoChun zhuang Li Guangdong Key Laboratory of Environmental Pollution and Health College of Environment and ClimateJinan University

Nitrogen（N）, an essential nutrient element in paddy soils, is crucial for rice production. N-cycling in soils is mainly mediated by microorganisms; thus,the potential of N-cycling can be evaluated based on the structure of microbial communities that participated in the N-cycling processes. In paddy soils, biological nitrification and denitrification are the primary processes for N fertilizer use, N loss, and N2O emission.

关键词： AMMONIA-OXIDIZING BACTERIA ARCHAEA

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A novel stiffness optimization model of space telescopic boom based on locking mechanism

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Frontiers of Mechanical Engineering 2024年第3期19卷 41-59页

作者： Kun XU Xinghan zhuang zhou SU Qiuhong LIN Shouzhi REN Hang XIAO Xilun DING School of Mechanical Engineering and Automation Beihang UniversityBeijing 100191China Beijing Institute of Spacecraft System Engineering Beijing 100094China

The deployable telescopic boom,whose mass and stiffness play crucial roles,is extensively used in the design of space-deployable ***,the most existing optimal design that neglects the influence of the locking mechanisms in boom joints cannot raise the whole stiffness while reducing the boom *** tackle this challenge,a novel optimization model,which utilizes the arrangement of the locking mechanisms to achieve synchronous improvement of the stiffness and mass,is *** proposed optimization model incorporates a novel joint stiffness model developed based on an equivalent parallel mechanism that enables the consideration of multiple internal stiffness factors of the locking mechanisms and tubes,resulting in more accurate representations of the joint stiffness *** analysis shows that the proposed stiffness model achieves more than at least 11% improved accuracy compared with existing ***,case verification shows that the proposed optimization model can improve stiffness while effectively reducing mass,and it is applied in boom optimization design.

关键词： deployable telescopic boom locking mechanism stiffness model clearance error optimization model

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Observation and analysis of positive leader re-illumination in a 10 m ultra-high voltage transmission line gap under switching impulse voltages

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Plasma Science and Technology 2024年第10期26卷 93-100页

作者： Biao HUANG Xuan zhou She WANG Chijie zhuang Rong ZENG Le DENG Eliet Engineering School Changsha University of Science&TechnologyChangsha 410114People’s Republic of China State Key Laboratory of Disaster Prevention&Reduction for Power Grid Changsha University of Science&TechnologyChangsha 410114People’s Republic of China China International Engineering Consulting Co. Ltd.Beijing 100048People’s Republic of China Department of Electrical Engineering Tsinghua UniversityBeijing 100084People’s Republic of China

The leader propagation is one of the most important stages in long air gap *** mechanism behind leader re-illumination remains *** high humidity conditions(20.0–30.1 g/m^(3)),we have conducted experiments of long sparks in a 10 m ultra-high voltage(UHV)transmission line gap under switching impulse *** positive leaders predominantly propagate discontinuously,with almost no significantly continuous propagation *** leader channels are intensely luminous and each elongation segment is straight,with streamers resembling the“branch type”which differs from the“diffuse type”streamers at the front of continuous propagation *** distribution of the propagation velocities is highly random(3.7–18.4 cm/μs),and the average velocity(9.2 cm/μs)significantly exceeds that of continuous propagation(1.5–2.0 cm/μs).Analysis suggests that the current-velocity models suitable for continuous leader propagation do not align well with the experimental data in re-illumination *** on the discharge current waveforms and optical images,it is speculated that the newly elongated leader in re-illumination mode does not evolve gradually from the stem(about 1 cm)but rather evolves overall from a thermal channel much longer than stem.

关键词： long air gap discharge positive leader re-illumination discontinuous leader propagation

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Novel wreck salvaging method using curved rectangular pipe basing method:A case study of"Yangtze River EstuaryⅡ"ancient shipwreck salvage project

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Underground Space 2024年第5期18卷 97-113页

作者： Qianwei zhuang Guofang Gong Dongrong zhou Chi Zhang Xin Huang Xiaodong Zhu Weihao Yuan Deng Li School of Mechanical Engineering Zhejiang UniversityHangzhou 310030China Shanghai Tunnel Engineering Co.Ltd. Shanghai 200137China Department of Geotechnical Engineering College of Civil EngineeringTongji UniversityShanghai 200092China College of Civil Engineering and Architecture Xinjiang UniversityUrumqi 830047China Shanghai Salvage Company Shanghai 200090China

Shipwreck salvage is a risky,time-consuming,and expensive *** there are many sunken ships along coastlines and in the open seas,the salvage process of a sunken ship has rarely been *** integrated salvage of the"Yangtze River EstuaryⅡ"shipwreck used a novel method with 22 closely locked curved rectangular pipes to form a watertight base that wrapped the shipwreck *** basing was lifted out of the water using a powerful crane situated on an engineering *** the first time,the tunneling method was used in a shipwreck salvage project,significantly reducing the disturbance to the shipwreck and its stowage,thereby preserving the original state and integrity of the shipwreck to the greatest *** this study,the basic concepts of the salvage method and process are *** to critical issues in the new salvage method are provided,including jacking force prediction and major considerations for the structural design of the salvage *** design of the salvage system and salvage process of the"Yangtze River EstuaryⅡ"shipwreck are *** monitored jacking force,pipe deformation,and observed water-tightness verified that the proposed method was effective and *** possible application scenarios for the proposed method are presented at the end.

关键词： Pipe jacking Shipwreck salvage Yangtze River EstuaryⅡ Structural design

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Existence of multi-hump generalized homoclinic solutions for a class of reversible systems

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Science China Mathematics 2024年

作者： Shengfu Deng Yan zhou Jinsen zhuang School of Mathematical Sciences Huaqiao University

In this paper, we investigate a class of reversible dynamical systems in four dimensions. The spectrums of their linear operators at the equilibria are assumed to have a pair of positive and negative real eigenvalues and a pair of purely imaginary eigenvalues for the small parameterμ> 0, where these two real eigenvalues bifurcate from a double eigenvalue 0 forμ=0. It has been shown that this class of systems owns a generalized homoclinic solution with one hump at the center （a homoclinic solution exponentially approaching a periodic solution with a small amplitude）. This paper gives a rigorous existence proof of two-hump *** two humps are far away and are glued by the small oscillations in the middle if some appropriate free constants are activated. The obtained results are also applied to some classical systems. The ideas here may be used to study the existence of 2k-hump solutions.

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