检索结果-南通市图书馆

Journal of Harbin Institute of Technology(New Series) 2014年第4期21卷 96-102页

作者： Wen-Jing Dong Tie-Jun Zhou run-zhao qi Chongqing University Faculty of Architecture and Urban Planning Key Laboratory of New Technology for Construction of Cities in Mountain Area

At present,a large number of historic buildings on campus are lack of energy-saving measures from the design time,especially the dormitories. And the reconstruction mostly focuses on functional reorganization or furniture replacement. However,energy efficiency design has not been paid enough attention,which leads to the high building energy consumption and the harsh physical environment. Based on the analysis of climatic characteristics of Chongqing area,taking Dormitory Six on campus B of Chongqing University as an example,the reconstruction of rooms on the top floor and West end are focused to guarantee the equal benefits of the dormitory environment. Through the simulation analysis of the software, on the basis of energy saving reconstruction of common maintenance structure,this thesis discusses the energy saving reconstruction methods and strategies of the existing campus dormitories,which are more suitable for the existing campus dormitories in Chongqing area.

关键词： campus dormitories in Chongqing energy-saving reconstruction optimization reconstruction design planted roof greening of West walls

Flexible molecules dedicate to release strain of inverted inorganic perovskite solar cell

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 87-93页

作者： Hongrui Sun Sanlong Wang Pengyang Wang Yali Liu Shanshan qi Biao Shi Ying zhao Xiaodan Zhang Institute of Photoelectronic Thin Film Devices and Technology Renewable Energy Conversion and Storage Center State Key Laboratory of Photovoltaic Materials and CellsNankai University Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin Haihe Laboratory of Sustainable Chemical Transformations Engineering Research Center of Thin Film Photoelectronic Technology of Ministry of Education Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)

The tensile strain in inorganic perovskite films induced by thermal annealing is one of the primary factors contributing to the inefficiency and instability of inorganic perovskite solar cells （IPSCs）,which reduces the defect formation ***,a flexible molecule 5-maleimidovaleric acid （5-MVA） was introduced as a strain buffer to release the residual strain of *** anhydride and carboxyl groups in 5-MVA interact strongly with the uncoordinated Pb2+through Lewis acid-base reaction,thus tightly“pull”the perovskite *** in-between soft carbon chain increased the structural flexibility of CsPbI2.85Br0.15perovskite materials,which effectively relieved the intrinsic internal strain of CsPbI2.85Br0.15,resisted the corrosion of external strain,and also reduced the formation of defects such as VIand *** addition,the introduction of 5-MVA improved crystal quality,passivated residual defects,and narrowed energy level ***,power conversion efficiency （PCE） of NiOxbased inverted IPSCs increased from 19.25% to 20.82% with the open-circuit voltage enhanced from 1.164 V to 1.230 *** release of strain also improved the stability of CsPbI2.85Br0.15perovskite films and devices.

关键词： Inverted inorganic perovskite solar cells Flexible molecules Strain release Crystallization Energy barrier High PCE

Lipid droplets in the nervous system:involvement in cell metabolic homeostasis

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第3期20卷 740-750页

作者： Yuchen Zhang Yiqing Chen Cheng Zhuang Jingxuan qi Robert Chunhua zhao Jiao Wang School of Life Sciences Shanghai UniversityShanghaiChina School of Medicine Shanghai UniversityShanghaiChina Institute of Basic Medical Sciences Chinese Academy of Medical Sciences School of Basic MedicinePeking Union Medical CollegeBeijingChina Center of Excellence in Tissue Engineering Chinese Academy of Medical SciencesBeijingChina Beijing Key Laboratory of New Drug Development and Clinical Trial of Stem Cell Therapy BeijingChina

Lipid droplets serve as primary storage organelles for neutral lipids in neurons,glial cells,and other cells in the nervous *** droplet formation begins with the synthesis of neutral lipids in the endoplasmic ***,lipid droplets were recognized for their role in maintaining lipid metabolism and energy homeostasis;however,recent research has shown that lipid droplets are highly adaptive organelles with diverse functions in the nervous *** addition to their role in regulating cell metabolism,lipid droplets play a protective role in various cellular stress ***,lipid droplets exhibit specific functions in neurons and glial *** of lipid droplet formation leads to cellular dysfunction,metabolic abnormalities,and nervous system *** review aims to provide an overview of the role of lipid droplets in the nervous system,covering topics such as biogenesis,cellular specificity,and ***,it will explore the association between lipid droplets and neurodegenerative *** the involvement of lipid droplets in cell metabolic homeostasis related to the nervous system is crucial to determine the underlying causes and in exploring potential therapeutic approaches for these diseases.

关键词： Alzheimer's disease lipid droplet biogenesis lipid droplets lipid metabolism nervous system neurodegenerative disorders oxidative stress Parkinson's disease

在线全文

学校读者我要写书评

暂无评论

湖北咸宁细颗粒物PM_(2.5)来源

环境科学 2024年第4期45卷 1983-1993页

作者：罗怡朱宽广陈璞珑田军谢旻战杨志豪赵润琪南京大学大气科学学院南京210023 湖北省环境科学研究院武汉430072 净零纪元(江苏)环境科技有限公司南京210023 南京大学环境规划设计研究院集团南京210093

为了解咸宁细颗粒物(PM_(2.5))来源,对2019年在湖北咸宁两个环境受体点位采集的不同季节大气中PM_(2.5)样品中的主要成分和化学元素进行统计研究;通过颗粒物排放源采样建立本地特征源谱,用化学质量平衡(CMB)受体模型解析其来源;通过VOC... 详细信息

为了解咸宁细颗粒物(PM_(2.5))来源,对2019年在湖北咸宁两个环境受体点位采集的不同季节大气中PM_(2.5)样品中的主要成分和化学元素进行统计研究;通过颗粒物排放源采样建立本地特征源谱,用化学质量平衡(CMB)受体模型解析其来源;通过VOCs离线监测数据分析其中二次气溶胶(SOA)生成关键组分,并对关键组分进行来源解析.结果表明,咸宁市PM_(2.5)超标情况主要出现在冬季,PM_(2.5)中主要化学成分以水溶性无机盐和含碳组分为主;一次解析揭示硝酸盐、硫酸盐和铵盐等的二次转化对PM_(2.5)浓度的贡献最大,总贡献率在45%以上;二次解析揭示工业源、机动车源及电厂对PM_(2.5)浓度的贡献最大;VOCs对二次有机气溶胶贡献最高的组分为芳香烃,关键组分为苯、甲苯、间/对-二甲苯和乙基苯,对关键组分来源分析发现主要来源为溶剂使用.控制工业排放、机动车排放及调整能源结构是目前控制咸宁PM_(2.5)的主要途径,同时也要考虑控制溶剂排放的芳香烃.

关键词：咸宁市 PM_(2.5) 化学质量模型(CMB) 来源解析挥发性有机物(VOCs)

在线全文

学校读者我要写书评

暂无评论

咸宁市大气臭氧敏感性和污染来源解析

中国环境科学 2021年第9期41卷 4060-4068页

作者：任俊宇朱宽广谢旻刘巍高达陈嘉胜金宇宁赵润琪张林涛南京大学大气科学学院江苏南京210023 湖北省环境科学研究院湖北武汉430072

为掌握咸宁市臭氧(O_(3))污染状况,基于统计分析方法研究咸宁市2018年O_(3)地面观测数据,发现该年3~10月均有O_(3)浓度超标日发生,其中6、8、9、10月有浓度较高且持续时间较长的严重污染,高浓度时段集中于4~7月的每日12:00~20:00,浓度... 详细信息

为掌握咸宁市臭氧(O_(3))污染状况,基于统计分析方法研究咸宁市2018年O_(3)地面观测数据,发现该年3~10月均有O_(3)浓度超标日发生,其中6、8、9、10月有浓度较高且持续时间较长的严重污染,高浓度时段集中于4~7月的每日12:00~20:00,浓度峰值出现时间约为16:00前后.使用OBM模型模拟,借助EKMA曲线、RIR分析等识别O_(3)敏感性,发现咸宁属于VOCs控制区,O_(3)生成对人为源VOCs中的二甲苯类芳香烃和烯烃类较敏感,这两类物种浓度均削减10%后分别得到RIR值为0.271和0.238.开展离线VOCs监测,经PMF方法解析得到5类源,其中工业排放为O_(3)污染主要贡献源,二甲苯类芳香烃绝大部分来自溶剂使用,烯烃类主要来自燃烧源.当O_(3)超标时,相比于非超标日,植物源、溶剂使用和燃烧源的贡献率均有增加,其中植物源的贡献增量较大,而机动车尾气和工业排放的贡献率却有一定程度的降低.

关键词：臭氧臭氧前体物臭氧敏感性挥发性有机物 OBM PMF

在线全文

学校读者我要写书评

暂无评论

中原老区井壁稳定技术应用

探矿工程（岩土钻掘工程） 2012年第2期39卷 28-30,34页

作者：秦献民赵润琦路艳中原油田钻井二公司技术发展部河南濮阳457001

造成井壁失稳的原因是多方面的,主要影响可归结为力学因素、化学因素和工程技术因素。通过对2010年施工的钻井数据进行分析,对中原油田老区井壁稳定技术进行了研究。根据施工中遇到的问题,采取的措施,提出了对油田老区井壁稳定技术的一... 详细信息

造成井壁失稳的原因是多方面的,主要影响可归结为力学因素、化学因素和工程技术因素。通过对2010年施工的钻井数据进行分析,对中原油田老区井壁稳定技术进行了研究。根据施工中遇到的问题,采取的措施,提出了对油田老区井壁稳定技术的一些想法,利于提高油田老区钻井的速度和质量。

关键词：井壁稳定力学因素化学因素抑制性中原油田老区

Differential distribution of PINK1 and Parkin in the primate brain implies distinct roles

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第4期20卷 1124-1134页

作者： Yanting Liu Wei Huang Jiayi Wen Xin Xiong Ting Xu qi Wang Xiusheng Chen Xianxian zhao Shihua Li Xiaojiang Li Weili Yang Guangdong Key Laboratory of Non-human Primate Research Key Laboratory of CNS Regeneration(Ministry of Education)Guangdong-Hongkong-Macao CNS Regeneration Institute of Jinan UniversityJinan UniversityGuangzhouGuangdong ProvinceChina

The vast majority of in vitro studies have demonstrated that PINK1 phosphorylates Parkin to work together in mitophagy to protect against neuronal ***,it remains largely unclear how PINK1 and Parkin are expressed in mammalian *** has been difficult to address because of the intrinsically low levels of PINK1 and undetectable levels of phosphorylated Parkin in small *** this issue is critical for elucidating the in vivo roles of PINK1 and ***,we showed that the PINK1 kinase is selectively expressed as a truncated form(PINK1–55)in the primate *** the present study,we used multiple antibodies,including our recently developed monoclonal anti-PINK1,to validate the selective expression of PINK1 in the primate *** found that PINK1 was stably expressed in the monkey brain at postnatal and adulthood stages,which is consistent with the findings that depleting PINK1 can cause neuronal loss in developing and adult monkey ***1 was enriched in the membrane-bound fractionations,whereas Parkin was soluble with a distinguishable *** double staining experiments showed that PINK1 and Parkin did not colocalize under physiological conditions in cultured monkey astrocytes,though they did colocalize on mitochondria when the cells were exposed to mitochondrial *** findings suggest that PINK1 and Parkin may have distinct roles beyond their well-known function in mitophagy during mitochondrial damage.

关键词： neurodegeneration Parkin Parkinson’s disease PINK1 subcellular distribution

Laser direct writing of flexible multifunctional airflow sensors on the Kevlar fabric

在线全文

学校读者我要写书评

暂无评论

Nano Research 2025年第1期18卷 443-454页

作者： Wei Wang Zi-qing Chen Yong-qi Li Yu-Long Wang Mei-Chen Liu Yun-Bo Ruan Yang Zhang Shu-Juan Liu qiang zhao College of Electronic and Optical Engineering and College of Flexible Electronics(Future Technology) Nanjing University of Posts and TelecommunicationsNanjing 210023China State Key Laboratory of Organic Electronics and Information Displays and Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials(IAM)Nanjing University of Posts and TelecommunicationsNanjing 210023China Zhe Jiang Topsun Logistic Control CO. LTD.Yuhuan 317600China Department of Rehabilitation Medicine School of Acupuncture-Moxibustion and Tuina and School of Health Preservation and RehabilitationNanjing University of Chinese MedicineNanjing 210023China

The growing interest in flexible devices has emerged as a global trend due to their advantages in flexibility,lightweight structure,and wearability,addressing the limitations of traditional *** wearable airflow sensors have been previously reported,the development of flexible fabric-based airflow sensors capable of functioning in environments with open flames—critical for fire rescue operations—has yet to be explored,largely due to the poor fire resistance of conventional *** this work,we first present a flexible,wearable,and multifunctional airflow sensor with excellent fire-resistant properties,fabricated through a simple direct laser writing *** sensor maintains airflow detection capabilities even in the presence of open ***,the fabrication of fabric-based sensors involves complex procedures such as carbon materials doping or vapor-phase deposition,leading to lengthy preparation cycles and high ***,fabric-based devices are inherently prone to *** address these challenges,we introduce twice-vertical laser-induced graphene(TVLIG)as a sensitive and reliable component for fire-resistant airflow *** resulting TVLIG/Kevlar fabric can be integrated into various garments,particularly protective suits,to form sensitive and fire-resistant airflow sensors capable of detecting airflow velocity and direction in both two-dimensional(2D)and three-dimensional(3D)spaces during fire ***,the TVLIG patterns can be expanded to multifunctional platforms,such as glucose detection for injured individuals,offering further applications in rescue *** functional expansion reduces the burden on rescue personnel and streamlines device *** its outstanding sensing capabilities,fire resistance,and expandability,the developed flexible airflow sensor shows great potential for various real-world rescue scenarios,promising advancements in wearable sensing technology for rescue enginee

关键词： flexible airflow sensor direct laser writing twice-vertical laser-induced graphene fire accident rescue Kevlar fabric

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

有限性与延展性:新中国国家安全思想的演进

国际安全研究 2025年第1期43卷 73-95,157页

作者：祁昊天赵书韫北京大学国际关系学院国家安全学系北京100871

文章从国家安全本体论、安全体系认识论与安全实践方法论三个维度考察新中国的国家安全思想,以社会主义革命和建设时期、改革开放和社会主义现代化建设新时期以及中国特色社会主义新时代进行时间分段,讨论新中国国家安全思想的演进。有... 详细信息

文章从国家安全本体论、安全体系认识论与安全实践方法论三个维度考察新中国的国家安全思想,以社会主义革命和建设时期、改革开放和社会主义现代化建设新时期以及中国特色社会主义新时代进行时间分段,讨论新中国国家安全思想的演进。有限性与延展性是这一演进过程中安全思想的连贯体现,分别涵盖了安全目标、认知与方法在各阶段静态与动态、横向与纵向的特征。虽然新中国在不同时期面临不同的安全环境和安全需求,安全形势愈加复杂,但是安全思想和实践总体符合安全有限、延展演进的特征。安全具有弹性但不可过载,不存在绝对安全的空间,而狭义的、单一领域或维度的安全亦无法有效支撑对国家安全的维护,特别是在愈加复杂和不确定的国家安全环境中更是如此。新中国国家安全思想“有限—延展”的演进特征反映了安全环境的客观变化与领导人主观能动的决策部署。

关键词：国家安全思想演进有限性延展性

Loss-of-function mutations of microRNA-142-3p promote ASH1L expression to induce immune evasion and hepatocellular carcinoma progression

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第1期31卷 126-145页

作者： Xing-Hui Yu Yan Xie Jian Yu Kun-Ning Zhang Zhou-Bo Guo Di Wang zhao-Xian Li Wei-qi Zhang Yu-Ying Tan Li Zhang Wen-Tao Jiang School of Medicine Nankai UniversityTianjin 300192China Tianjin Key Laboratory of Molecular Diagnosis and Treatment of Liver Cancer Tianjin First Center HospitalTianjin 300192China Department of Liver Transplantation Tianjin First Center HospitalTianjin 300192China First Central Clinical School Tianjin Medical UniversityTianjin 300192China

BACKGROUND Hepatocellular carcinoma(HCC)has been a pervasive malignancy throughout the world with elevated *** therapeutic targets are beneficial to treat and predict the ***,the exact molecular mechanisms leading to the progression of HCC are still *** has shown that the microRNA-142-3p level decreases in HCC,whereas bioinformatics analysis of the cancer genome atlas database shows the ASH1L expression increased among liver tumor *** this paper,we will explore the effects and mechanisms of microRNA-142-3p and ASH1L affect the prognosis of HCC patients and HCC cell bioactivity,and the association between *** To investigate the effects and mechanisms of microRNA-142-3p and ASH1L on the HCC cell bioactivity and prognosis of HCC *** In this study,we grouped HCC patients according to their immunohistochemistry results of ASH1L with pathological tissues,and retrospectively analyzed the prognosis of HCC ***,explored the roles and mechanisms of microRNA-142-3p and ASH1L by cellular and animal experiments,which involved the following experimental methods:Immunohistochemical staining,western blot,quantitative real-time-polymerase chain reaction,flow cytometric analysis,tumor xenografts in nude mice,*** statistical methods involved in this study contained t-test,one-way analysis of variance,theχ^(2)test,the Kaplan-Meier approach and the log-rank *** In this study,we found that HCC patients with high expression of ASH1L possess a more recurrence rate as well as a decreased overall survival ***1L promotes the tumorigenicity of HCC and microRNA-142-3p exhibits reduced expression in HCC tissues and interacts with ASH1L through targeting the ASH1L 3′untranslated ***,microRNA-142-3p promotes apoptosis and inhibits proliferation,invasion,and migration of HCC cell lines in vitro via *** the exploration mechanism,we found ASH1L may promote an immunosuppressive mi

关键词： Hepatocellular carcinoma MicroRNA-142-3p ASH1L Immune evasion Tumor immune microenvironment Apoptosis