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Magnesium-reinforced Electrospun Synthetic-polymer Nanofibers Designed for Promoting Tissue Growth

Journal of Bionic Engineering 2024年第3期21卷 1412-1426页

作者： Muheeb Rafiq Anjum Hamid Rather rumysa saleem khan Taha Umair Wani Haseeb A.khan Abdullah S.Alhomida Faheem A.Sheikh Nanostructured and Biomimetic Lab Department of NanotechnologyUniversity of Kashmir HazratbalSrinagarJammu and Kashmir190006India Non-Clinical Evaluation Center Biomedical Research InstituteJeonbuk National University HospitalJeonjuJeollabuk-do54907South Korea College of Pharmacy and Research Institute of Pharmaceutical Sciences Gyeongsang National UniversityJinju52828South Korea Research Chair for Biomedical Applications of Nanomaterials Department of BiochemistryCollege of ScienceKing Saud UniversityRiyadh11451Saudi Arabia

The creation of 3D nanofibers offering desirable functions for bone regeneration is developed due to the latest improvisations to the electrospinning *** polymers are among the best choices for medical usage due to their lower costs,high tensile properties,and ease of spinnability compared to natural *** this communication,we report a series of interventions to polymers modified with Mg-based fillers for ideal tissue engineering *** literature survey indicated that these filler materials(e.g.,nano-sized particles)enhanced biocompatibility,antibacterial activity,tensile strength,and anti-corrosive *** review discusses electrospinning parameters,properties,and applications of the poly(ε-caprolactone),poly(lactic acid),poly(3-hydroxybutyric acid-co-3-hydroxy valeric acid),polyurethane,and poly(vinyl pyrrolidone)nanofibers when modified with Mg-based *** report encourages researchers to use synthetic polymers with Mg as fillers and validate them for tissue engineering applications.

关键词： Bone regeneration Magnesium Nanofibers Tissue engineering

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Recent progress in MXenes incorporated into electrospun nanofibers for biomedical application: Study focusing from 2017 to 2022

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Chinese Chemical Letters 2023年第7期34卷 38-44页

作者： Muheeb Rafiq Sami-ullah Rather Taha Umair Wani Anjum Hamid Rather rumysa saleem khan Anees Ellahi khan Ibtisam Hamid Haseeb A.khan Abdullah S.Alhomida Faheem A.Sheikh Nanostructured and Biomimetic Lab Department of NanotechnologyUniversity of Kashmir Hazratbal.Jammu and KashmirSrinagar 190006India Department of Chemical and Materials Engineering King Abdulaziz University.Jeddah 21589Saudi Arabia Research Chair for Biomedical Applications of Nanomaterials Department of BiochemistryCollege of ScienceKing Saud UniversityRiyadh 11451Saudi Arabia

After discovering a new class of two-dimensional(2D) material, i.e., MXene, a further new scope, came into existence for researchers. Due to their remarkable physical, chemical, and biological properties, MXenes find their role in almost every research discipline. They have been used in biosensors, bioimaging,tissue engineering, drug delivery systems, and other areas. The MXenes can be functionalized with a wide range of atoms/molecules, making them diverse materials. Therefore, the potential of using MXenes in nanofibers can be much more than expected. In this review, we will understand the structure, synthesis,and general properties of MXenes. We will explain using MXenes while encasing them into nanofibers,providing their specific properties. For instance, MXenes-incorporated nanofibers are used in biomedical applications, including soft and hard-tissue engineering and delivery of antimicrobials. Furthermore, MXenes, when incorporated into nanofibers, are used in promoting cellular differentiation, wound healing,and neural tissue restoration, which are briefly discussed in this communication.

关键词： MXenes Nanofibers Tissue engineering Antimicrobial Electrospinning

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