检索结果-南通市图书馆

The role of bacteria and its derived biomaterials in cancer radiotherapy

Acta Pharmaceutica Sinica B 2023年第10期13卷 4149-4171页

作者： Yu Zhang ruizhe huang Yunchun Jiang Wenhao Shen Hailong Pei Guanglin Wang Pei Pei Kai Yang State Key Laboratory of Radiation Medicine and Protection School of Radiation Medicine and Protection&School for Radiological and Interdisciplinary Sciences(RAD-X)Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education InstitutionsSoochow UniversitySuzhou 215123China Teaching and Research Section of Nuclear Medicine School of Basic Medical SciencesAnhui Medical UniversityHefei 230032China

Bacteria-mediated anti-tumor therapy has received widespread attention due to its natural tumor-targeting ability and specific immune-activation characteristics.It has made significant progress in breaking the limitations of monotherapy and effectively eradicating tumors,especially when combined with traditional therapy,such as radiotherapy.According to their different biological characteristics,bacteria and their derivatives can not only improve the sensitivity of tumor radiotherapy but also protect normal tissues.Moreover,genetically engineered bacteria and bacteria-based biomaterials have further expanded the scope of their applications in radiotherapy.In this review,we have summarized relevant researches on the application of bacteria and its derivatives in radiotherapy in recent years,expounding that the bacteria,bacterial derivatives and bacteria-based biomaterials can not only directly enhance radiotherapy but also improve the anti-tumor effect by improving the tumor microenvironment(TME)and immune effects.Furthermore,some probiotics can also protect normal tissues and organs such as intestines from radiation via anti-inflammatory,anti-oxidation and apoptosis inhibition.In conclusion,the prospect of bacteria in radiotherapy will be very extensive,but its biological safety and mechanism need to be further evaluated and studied.

关键词： Bacterial therapy Radiotherapy Engineered bacteria Bacteria-based biomaterials Radio-protector Radio-sensitization Radiation-activation Synergy effect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High-performance flexible nanocomposites with superior fire safety and ultra-efficient electromagnetic interference shielding

引用

Journal of Materials Science & Technology 2023年第35期166卷 133-144页

作者： Miao Liu Kexin Chen Yongqian Shi Hengrui Wang Shijie Wu ruizhe huang Yuezhan Feng Longcheng Tang Xiaohuan Liu Pingan Song College of Environment and Safety Engineering Fuzhou UniversityFuzhou 350116China Key Laboratory of Materials Processing and Mold Ministry of Education National Engineering Research Center for Advanced Polymer Processing TechnologyZhengzhou UniversityZhengzhou 450002China Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education College of MaterialChemistry and Chemical EngineeringHangzhou Normal UniversityHangzhou 311121China College of Life Science Zhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and ConservationTaizhou UniversityTaizhou 318000China Centre for Future Materials University of Southern QueenslandSpringfieldQLD 4300Australia School of Agriculture and Environmental Science University of Southern QueenslandSpringfield4300Australia

High-performance multifunctional polymeric materials integrated with high fire safety,excel-lent mechanical performances and electromagnetic interference(EMI)shielding properties have great prospects in practical applications.However,designing highly fire-safe and mechanically ro-bust EMI shielding nanocomposites remains a great challenge.Herein,hierarchical thermoplastic polyurethane/cyclophosphazene functionalized titanium carbide/carbon fiber fabric(TPU/CP-Ti_(3)C_(2)T_(x)/CF)nanocomposites with high fire safety and mechanical strength and toughness were prepared through the methods of melt blending,layer-by-layer stacking and thermocompression.The TPU/CP-Ti_(3)C_(2)T_(x)showed improved thermal stability.Moreover,the peak of heat release rate and total heat release of the hi-erarchical TPU sample containing 4.0 wt.%CP-Ti_(3)C_(2)T_(x)were respectively reduced by 64.4%and 31.8%relative to those of pure TPU,which were far higher than those of other TPU-based nanocomposites.The averaged EMI shielding effectiveness value of the hierarchical TPU/CP-Ti_(3)C_(2)T_(x)-2.0/CF nanocomposite reached 30.0 dB,which could satisfy the requirement for commercial applications.Furthermore,the ten-sile strength of TPU/CP-Ti_(3)C_(2)T_(x)-2.0/CF achieved 43.2 MPa,and the ductility and toughness increased by 28.4%and 84.3%respectively compared to those of TPU/CF.Interfacial hydrogen bonding in combination with catalytic carbonization of CP-Ti_(3)C_(2)T_(x)nanosheets and continuous conductive network of CF were re-sponsible for the superior fire safety,excellent EMI shielding and outstanding mechanical performances.This work offers a promising strategy to prepare multifunctional TPU-based nanocomposites,which have the potential for large-scale application in the fields of electronics,electrical equipment and 5 G facilities.

关键词： Hierarchical structure Fire safety Electromagnetic interference shielding Mechanical strength and toughness Air assisted thermocompression

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Facile preparation of^(177)Lu-microspheres for hepatocellular carcinoma radioisotope therapy

引用

Chinese Chemical Letters 2022年第7期33卷 3492-3496页

作者： Manran Wu Kexin Shi ruizhe huang Chunyi Liu Lingling Yin Weipeng Yong Jing Sun Guanglin Wang Zhiyuan Zhong Mingyuan Gao State Key Laboratory of Radiation Medicine and Protection School of Radiation Medicine and Protection&School for Radiological and Interdisciplinary Sciences(RAD-X)Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education InstitutionsSoochow UniversitySuzhou 215123China Biomedical Polymers Laboratory College of ChemistryChemical Engineering and Materials ScienceState Key Laboratory of Radiation Medicine and ProtectionSoochow UniversitySuzhou 215123China

As one of the most common cancers in the world,hepatocellular carcinoma(HCC)has become a major threat to human health.Radioembolization is a first-line option for the treatment of HCC,especially when other conventional treatments fail or there exist some relative contraindications.Herein,we developed a facile and efficient method for preparing ^(177)Lu-microspheres potentially useful for precise radioembolization therapy of HCC.The radiolabeling efficiency of ^(177)Lu-microspheres was as high as 96.8%±0.5%,and the radiolabeling process did not alter the morphology of the mother microspheres.The SPECT/CT studies enabled by the unique emissions of ^(177)Lu suggested that almost no ^(177)Lu ion loaded by the microspheres was released over more than 32 d in vivo,which led to remarkable inhibition effect on the growth of HepG2 tumors subcutaneously transplanted in mice.The current approach may thus offer promising ^(177)Lu-microspheres for clinical radioembolization of HCC.

关键词： Radioisotope Radioactive microspheres Hepatocellular carcinoma SPECT/CT Radioembolization therapy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于生成式对抗网络和多模态注意力机制的扩频与常规调制信号识别方法

引用

电子与信息学报 2024年第4期46卷 1212-1221页

作者：王华华张睿哲黄永洪重庆邮电大学通信与信息工程学院重庆400065 移动通信技术重庆市重点实验室重庆400065 重庆邮电大学网络空间安全与信息法学院重庆400065

针对低信噪比条件下的扩频与常规调制信号分类精度低的问题,该文提出一种基于生成式对抗网络(GAN)、卷积神经网络(CNN)和长短期记忆(LSTM)网络的多模态注意力机制信号调制识别方法。首先生成待识别信号的时频图像(TFIs),并利用GAN实现T... 详细信息

针对低信噪比条件下的扩频与常规调制信号分类精度低的问题,该文提出一种基于生成式对抗网络(GAN)、卷积神经网络(CNN)和长短期记忆(LSTM)网络的多模态注意力机制信号调制识别方法。首先生成待识别信号的时频图像(TFIs),并利用GAN实现TFIs降噪处理;然后将信号的同相正交数据(I/Q data)与TFIs作为模型输入,并搭建基于CNN的TFIs识别支路和基于LSTM的I/Q数据识别支路;最后,在模型中添加注意力机制,增强I/Q数据和TFIs中重要特征对分类结果的决定作用。实验结果表明,该文所提方法相较于单模态识别模型以及其它基线模型,整体分类精度有效提升2%~7%,并在低信噪比条件下具备更强的特征表达能力和鲁棒性。

关键词：深度学习自动调制识别生成对抗网络(GAN) 多模态特征时频分布

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

多维度大容量超表面全息及光场变换

引用

光学学报 2024年第2期44卷 52-61页

作者：陈彦杰徐正琨赵睿哲李晓炜王涌天黄玲玲北京理工大学光电学院北京市混合现实与新型显示工程技术研究中心北京100081 北京理工大学光电学院光电成像技术与系统教育部重点实验室北京100081 北京理工大学光电学院信息光子技术工信部重点实验室北京100081 北京理工大学机械与车辆学院激光微纳制造实验室北京100081

超表面的设计与制造极大地推动了在片上紧凑光学系统中实现光场调控的应用。传统光学系统中的光学透镜、空间光调制器以及偏振光学元件虽具备光场调控的功能,但体积庞大、光场调控功能单一等因素限制了其应用。超表面为光场调控提供了... 详细信息

超表面的设计与制造极大地推动了在片上紧凑光学系统中实现光场调控的应用。传统光学系统中的光学透镜、空间光调制器以及偏振光学元件虽具备光场调控的功能,但体积庞大、光场调控功能单一等因素限制了其应用。超表面为光场调控提供了新平台,有望解决传统光学元件和系统向微型化、集成化和多功能化发展的瓶颈。主要围绕超表面的多维度全息混合复用、二维/三维光场变换、矢量光场的产生与操控三方面进行介绍。最后,对超表面的未来发展趋势进行了展望。

关键词：超表面多维度光场调控全息成像光束整形

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

^(125)I粒子近距离照射在口腔颌面部恶性肿瘤治疗中的临床应用进展

引用

中华核医学与分子影像杂志 2024年第4期44卷 253-256页

作者：魏婷倪前伟杨自更黄孝泳孙海涛孙睿哲马超蔡冰冰高瞻新疆医科大学研究生院乌鲁木齐830054 新疆军区总医院颌面外科乌鲁木齐830000 新疆军区总医院核医学科乌鲁木齐830000 北京大学第三医院肿瘤放疗科北京100191 新疆军区总医院医学影像科乌鲁木齐830000

口腔颌面部恶性肿瘤威胁患者生命健康,严重影响患者的吞咽、语言功能和面容。其治疗方法中,^(125)I粒子近距离照射治疗技术因手术创伤小,靶区组织剂量大分布均匀,对周边正常组织损伤小,可以减少医护人员辐射暴露等优点,受到广泛关注。利... 详细信息

口腔颌面部恶性肿瘤威胁患者生命健康,严重影响患者的吞咽、语言功能和面容。其治疗方法中,^(125)I粒子近距离照射治疗技术因手术创伤小,靶区组织剂量大分布均匀,对周边正常组织损伤小,可以减少医护人员辐射暴露等优点,受到广泛关注。利用^(125)I粒子对口腔颌面部肿瘤进行持续、低剂量的近距离照射治疗,可以有效减小肿瘤体积,延长患者的生存期,治疗效果显著。该文针对^(125)I粒子近距离照射在口腔颌面部恶性肿瘤的临床应用展开综述。

关键词：口腔肿瘤近距离放射疗法碘放射性同位素发展趋势

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Detail correction for Gross classification of esophageal atresia based on 434 cases in China

引用

Chinese Medical Journal 2022年第4期135卷 485-487页

作者： Shen Yang ruizhe Yang Xiaofan Ma Shuangfeng Yang Yun Peng Qiang Tao Kuai Chen Junfeng Tao Yanan Zhang Jingbin Du Jinshi huang Xiaoxia Peng Department of Neonatal Surgery Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijing 100045China Department of Otorhinolaryngology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Key Laboratory of Animal Ecology and Conservation Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Department of Radiology Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijing 100045China Department of Neonatal Surgery The Affiliated Children’s Hospital of Nanchang UniversityNanchangJiangxi 330006China Center for Clinical Epidemiology and Evidence-based Medicine Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijing 100045China

To the Editor:Esophageal atresia(EA)is the most common congenital abnormality of the esophagus.In 70%to 90%of those born with EA,a tracheoesophageal fistula(TEF)co-occurs.Since Vogt[1]recognized and classified the types of anomalies in 1929,many other classification systems have been proposed,including the Ladd,Gross,Swenson,and Kluth classification systems.[2]However,the Gross classification of anatomical patterns of EA/TEF proposed in 1953 is one of the most widely accepted and used classification systems[3]and has been cited in Pediatric Surgery.[4]While surgical and imaging techniques have evolved considerably over recent decades,434 consecutive cases of EA/TEF in China were reviewed.Through closely examining the imaging studies and the pathoanatomical configurations of these patients,we identified certain"defects"and details in the illustrations that need modification.

关键词： illustration details

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Anchoring Single Nickel Atoms on Carbon-vacant Carbon Nitride Nanosheets for Efficient Photocatalytic Hydrogen Evolution

引用

Chemical Research in Chinese Universities 2022年第5期38卷 1243-1250页

作者： LIN Zhi ZHANG Zhengqi WANG Yiqing PENG Zhiming WANG Xinxin WANG ruizhe huang Yu-Cheng MENG Fanqi LI Mingtao DONG Chung-Li ZHANG Qinghua GU Lin SHEN Shaohua International Research Center for Renewable Energy State Key Laboratory of Multiphase Flow in Power EngineeringXi'an Jiaotong UniversityXi'an 710049P.R.China Department of Physics Tamkang UniversityNew Taipei City 25137TaiwanP.R.China Institute of Physics Chinese Academy of SciencesBeijing 100190P.R.China

Polymeric carbon nitride(PCN)has emerged as a promising candidate for photocatalytic hydrogen evolution,but its dependence on scarce and high-cost noble metal co-catalysts severely limits its extensive application.It will be of great promise to develop non-noble metal single-atom co-catalysts with low-cost and high atom utilization to improve the photocatalytic performance over PCN.Herein,single Ni atoms are successfully anchored onto carbon-vacant PCN nanosheets(CCN-SANi)via a two-step ammonia thermal treatment and photo-deposition process.Theoretical calculations and experimental results demonstrate that the optical absorption property and the charge transfer ability of CCN-SANi have been significantly improved with the introduction of single Ni atoms to form Ni-N3 sites.In comparison to carbon-vacant PCN(CCN)loaded with Ni clusters,the obtained CCN-SANi exhibits 11.4 times increased photocatalytic performance,with the highest hydrogen evolution rate reaching 511μmol/(g·h),which is even 1.7 times higher than that of CCN loaded with Pt clusters.This research proposes an inspiring and reliable strategy to design novel single-atom semiconducting polymers with electronic structures manipulated for efficient photocatalysis.

关键词： Photocatalytic hydgogen evolution Single metal atom Polymeric carbon nitride

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Time-sequential color code division multiplexing holographic display with metasurface

引用

Opto-Electronic Advances 2023年第8期6卷 8-16页

作者： Xin Li Qinmiao Chen Xue Zhang ruizhe Zhao Shumin Xiao Yongtian Wang Lingling huang Beijing Engineering Research Center of Mixed Reality and Advanced Display School of Optics and PhotonicsBeijing Institute of TechnologyBeijing 100081China MoE Key Laboratory of Photoelectronic Imaging Technology and System and MIIT Key Laboratory of Photonics Information TechnologySchool of Optics and PhotonicsBeijing Institute of TechnologyBeijing 100081China State Key Laboratory on Tunable Laser Technology Ministry of Industry and Information Technology Key Lab of Micro-Nano Optoelectronic Information SystemHarbin Institute of Technology(Shenzhen)Shenzhen 518055China National Key Laboratory of Science and Technology on Advanced Composites in Special Environments Harbin Institute of TechnologyHarbin 150080China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China

Color metasurface holograms are powerful and versatile platforms for modulating the amplitude,phase,polarization,and other properties of light at multiple operating wavelengths.However,the current color metasurface holography can only realize static manipulation.In this study,we propose and demonstrate a multiplexing metasurface technique combined with multiwavelength code-division multiplexing(CDM)to realize dynamic manipulation.Multicolor code references are utilized to record information within a single metasurface and increase the information capacity and security for anticracks.A total of 48 monochrome images consisting of pure color characters and multilevel color video frames were reconstructed in dual polarization channels of the birefringent metasurface to exhibit high information density,and a video was displayed via sequential illumination of the corresponding code patterns to verify the ability of dynamic manipulation.Our approach demonstrates significant application potential in optical data storage,optical encryption,multiwavelengthversatile diffractive optical elements,and stimulated emission depletion microscopy.

关键词： metasurface color holography dynamic display code division multiplexing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

IMB模型联合延续性口腔健康教育在妊娠期妇女口腔管理中的应用

引用

宁夏医学杂志 2024年第6期46卷 511-515页

作者：李玲玲李梦媛焦姣张馨李亚荣米璇刘颖蓉黄瑞哲西安交通大学口腔医院陕西省颅颌面精准医学研究重点实验室陕西西安710004 西安交通大学口腔医院口腔预防保健中心陕西西安710004 宁夏银川市口腔医院预防保健科宁夏银川750002

目的探究并分析信息-动机-行为技巧(IMB)模型联合延续性口腔健康教育在妊娠期妇女口腔管理中的应用价值。方法选取妊娠期妇女440例,其中失访40例,最终入组400例,采用随机数字表法将其随机分为对照组和观察组,每组各200例。对照组均进... 详细信息

目的探究并分析信息-动机-行为技巧(IMB)模型联合延续性口腔健康教育在妊娠期妇女口腔管理中的应用价值。方法选取妊娠期妇女440例,其中失访40例,最终入组400例,采用随机数字表法将其随机分为对照组和观察组,每组各200例。对照组均进行传统口腔健康教育,观察组实施IMB模型联合延续性口腔健康教育,分别于干预前、干预后第3个月、第6个月对2组孕妇进行菌斑指数(PLI)、牙龈出血指数(GBI)、牙周袋深度(PD)、简化牙石指数(CI-S)、简化软垢指数(DI-S)、龋易感性检查(Cariostat值),并对2组口腔保健知识认知和口腔行为改变情况进行调查评估。结果 PLI、GBI、PD、CI-S和DI-S得分组间、时间及交互比较差异均有统计学意义(P0.05),干预后3个月、干预后6个月观察组PLI、GBI、PD、CI-S和DI-S得分均低于对照组(P0.05),干预后3个月、干预后6个月观察组Cariostat值均低于对照组(P0.05),干预后3个月及干预后6个月观察组认知自我效能较高人数多于较低和一般人数(P0.05),干预后3个月及干预后6个月观察组健康行为较好人数多于一般和较差人数(P<0.05)。结论 IMB模型联合延续性口腔健康教育在妊娠期妇女口腔管理中的应用价值较高,有利于改善孕妇口腔状况,提升孕妇对口腔保健知识的认知,促进其保持良好的口腔行为习惯。

关键词：信息-动机-行为技巧模型延续性口腔健康教育妊娠期口腔管理

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：