检索结果-南通市图书馆

A systematic review of the role of TREM2 in Alzheimer’s disease

中华医学杂志(英文版) 2024年第14期137卷 1684-1694页

作者： Yin Yunsi Yang Hanchen li ruiyang Wu Guangshan Qin Qi Tang Yi Department of Neurology & Innovation Center for Neurological Disorders Xuanwu Hospital Capital Medical University National Center for Neurological Disorders Beijing China

Background: Given the established genetic linkage between triggering receptors expressed on myeloid cells 2 (TREM2) and Alzheimer’s disease (AD), an expanding research body has delved into the intricate role of TREM2 within the AD context. However, a conflicting landscape of outcomes has emerged from bothin vivo andin vitro investigations. This study aimed to elucidate the multifaceted nuances and gain a clearer comprehension of the role of ***: PubMed database was searched spanning from its inception to January 2022. The search criteria took the form of ( "Alzheimer’s disease" OR "AD" ) AND ( "transgenic mice model" OR "transgenic mouse model" ) AND ( "Triggering receptor expressed on myeloid cells" OR "TREM2" ). Inclusion criteria consisted of the following: (1) publication of original studies in English; (2) utilization of transgenic mouse models for AD research; and (3) reports addressing the subject of ***: A total of 43 eligible articles were identified. Our analysis addresses four pivotal queries concerning the interrelation of TREM2 with microglial function, Aβ accumulation, tau pathology, and inflammatory processes. However, the diverse inquiries posed yielded inconsistent responses. Nevertheless, the inconsistent roles of TREM2 within these AD mouse models potentially hinge upon factors such as age, sex, brain region, model type, and detection ***: This review substantiates the evolving understanding of TREM2’s disease progression-dependent impacts. Furthermore, it reviews the interplay between TREM2 and its effects across diverse tissues and temporal stages.

关键词： TREM2 Alzheimer’s disease Mouse model Microglia Amyloid-β accumulation Tau pathology Inflammation

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

特征提取与缩减在电力变压器异常状态检测的应用

引用

技术与市场 2024年第7期31卷 48-55页

作者：李瑞阳南京理工大学智能制造学院江苏南京210094

现有的三相干式变压器振动法状态检测,是一种利用从高频振动数据中提取特征,从而实现检测的方法。为了更准确地挖掘高频振动信号中的有效特征,提高诊断准确性,针对高频振动信号,将连续信号划分为独立的周期片段,从每一个周期中提取信号... 详细信息

现有的三相干式变压器振动法状态检测,是一种利用从高频振动数据中提取特征,从而实现检测的方法。为了更准确地挖掘高频振动信号中的有效特征,提高诊断准确性,针对高频振动信号,将连续信号划分为独立的周期片段,从每一个周期中提取信号的时域、频域和时频域特征;利用变压器振动原理分析,结合相关性分析给出特征选取策略;将筛选后的特征作为故障的特征值对振动进行实时的异常检测。结果表明:该方法可有效提取变压器振动信号特征,提高诊断准确率。

关键词：振动信号特征提取电力变压器异常检测

来源：

维普期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

基于Python+SQlite的文件整理软件设计与实现

引用

现代信息科技 2024年第1期8卷 28-31,38页

作者：李瑞洋周全兴凯里学院大数据工程学院贵州凯里556011

针对计算机中存储的文件日渐繁多,用于整理归纳的时间逐年上升的问题,采用Python中自带的os、date time、SQlite3、threading、hashlib和tkinter等数据库设计一款文件整理软件。该软件主要提供处理重复文件、提取目录下文件并重命名文... 详细信息

针对计算机中存储的文件日渐繁多,用于整理归纳的时间逐年上升的问题,采用Python中自带的os、date time、SQlite3、threading、hashlib和tkinter等数据库设计一款文件整理软件。该软件主要提供处理重复文件、提取目录下文件并重命名文件等功能。测试结果表明,该文件整理软件操作便捷,其整理效率远远高于传统整理方式,尤其是文件量大的情况下效果更明显。

关键词： Python SQlite数据库文件整理

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Physics-informed deep learning for solving phonon Boltzmann transport equation with large temperature non-equilibrium

引用

npj Computational Materials 2022年第1期8卷 245-254页

作者： ruiyang li Jian-Xun Wang Eungkyu Lee Tengfei Luo Department of Aerospace and Mechanical Engineering University of Notre DameNotre DameIN46556USA Department of Electronic Engineering Kyung Hee UniversityYongin-siGyeonggi-do17104South Korea Department of Chemical and Biomolecular Engineering University of Notre DameNotre DameIN46556USA Center for Sustainable Energy of Notre Dame(ND Energy) University of Notre DameNotre DameIN46556USA

Phonon Boltzmann transport equation(BTE)is a key tool for modeling multiscale phonon transport,which is critical to the thermal management of miniaturized integrated circuits,but assumptions about the system temperatures(i.e.,small temperature gradients)are usually made to ensure that it is computationally *** include the effects of large temperature non-equilibrium,we demonstrate a data-free deep learning scheme,physics-informed neural network(PINN),for solving stationary,mode-resolved phonon BTE with arbitrary temperature *** scheme uses the temperature-dependent phonon relaxation times and learns the solutions in parameterized spaces with both length scale and temperature gradient treated as input *** experiments suggest that the proposed PINN can accurately predict phonon transport(from 1D to 3D)under arbitrary temperature ***,the proposed scheme shows great promise in simulating device-level phonon heat conduction efficiently and can be potentially used for thermal design.

关键词： phonon equilibrium equation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

椭圆曲线y^(2)=(x-2)(x^(2)+2x+m)的整数点

引用

沈阳大学学报（自然科学版） 2024年第2期36卷 179-184页

作者：曹雅丽杨海李瑞阳西安工程大学理学院陕西西安710048

设p是满足p≡5(mod12)的奇素数,q=p-3/2为奇素数或1,m为正整数且m=3p-8。运用初等数论的方法及四次丢番图方程的相关结果,给出了椭圆曲线y^(2)=(x-2)(x^(2)+2x+m)的所有整数点(x,y)。

关键词：椭圆曲线同余整数点勒让德符号四次丢番图方程

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

不同储存温度和时间对鸡蛋品质的影响

引用

畜禽业 2024年第7期35卷 9-14页

作者：李瑞阳郭艳张进良商丘师范学院生物与食品学院河南商丘476000

目的研究不同储存温度和储存时间对鸡蛋品质的影响。方法选取健康柴鸡蛋60枚分为A、B 2组,规模化养殖鸡蛋60枚分为C、D 2组,其中A、C组于4℃保存,B、D组于25℃保存,试验的第0、7、14、21、28天测定鸡蛋品质指标。结果在4℃下,储存时间(0... 详细信息

目的研究不同储存温度和储存时间对鸡蛋品质的影响。方法选取健康柴鸡蛋60枚分为A、B 2组,规模化养殖鸡蛋60枚分为C、D 2组,其中A、C组于4℃保存,B、D组于25℃保存,试验的第0、7、14、21、28天测定鸡蛋品质指标。结果在4℃下,储存时间(0~28 d)对柴鸡蛋和规模化养殖鸡蛋没有明显影响。在25℃,柴鸡蛋随着储存时间的延长,气室高度、蛋壳相对重、蛋黄相对重分别在第21、14、14天出现显著差异,蛋黄指数、浓蛋白含量、蛋清相对重分别在第7、28、28天出现显著差异。而规模化养殖鸡蛋在25℃随着储存时间的延长,气室高度在第21天出现显著差异,蛋黄指数、浓蛋白含量、蛋清相对重分别在第7、14、7天出现显著差异。结论鸡蛋在4℃储存时,能够有效延长鸡蛋的储存时间,且柴鸡蛋比规模化养殖鸡蛋耐储存。

关键词：储存温度储存时间鸡蛋品质

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Promote the conductivity of solid polymer electrolyte at room temperature by constructing a dual range ionic conduction path

引用

Journal of Energy Chemistry 2022年第1期31卷 395-403,I0011页

作者： ruiyang li Haiming Hua Yuejing Zeng Jin Yang Zhiqiang Chen Peng Zhang Jinbao Zhao College of Chemistry and Chemical Engineering State-Province Joint Engineering Laboratory of Power Source Technology for New Energy VehicleState Key Laboratory of Physical Chemistry of Solid SurfacesEngineering Research Center of Electrochemical TechnologyMinistry of EducationCollaborative Innovation Center of Chemistry for Energy MaterialsXiamen UniversityXiamen 361005FujianChina College of Energy Xiamen UniversityXiamen 361102FujianChina

Poly(ethylene oxide)(PEO)is a classic matrix model for solid polymer electrolyte which can not only dissociate lithium-ions(li^(+)),but also can conduct li^(+) through segmental motion in ***,the crystal aggregation state of PEO restricts the conduction of li^(+) especially at room *** this work,an amorphous polymer electrolyte with ethylene oxide(EO)and propylene oxide(PO)block structure(B-PEG@DMC)synthesized by the transesterification is firstly obtained,showing an ionic conductivity value of 1.1×10^(5) S/cm at room temperature(25℃).According to the molecular dynamics(MD)simulation,the PO segments would lead to an inconsecutive and hampered conduction of li^(+),which is not beneficial to the short range conduction of li^(+).Thus the effect of transformation of aggregation state on the improveme nt of ionic conductivity is not eno ugh,it is n ecessary to further consider the differe nt coupled behaviours of EO and PO segments with li^(+).In this way,we blend this amorphous polymer(B-PEG@DMC)with PEO to obtain a dual range ionic conductive solid polymer electrolyte(D-SPE)with further improved ionic conductivity promoted by constructing a dual range fast ionic conduction,which eventually shows a further improved ionic conductivity value of 2.3×10^(5) S/cm at room temperature.

关键词： Solid polymer electrolyte Amorphous polymer Ionic conductivity Room temperature Arrhenius equation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Highly Conductive Poly(Imide–Imine)Hybrid Vitrimer-Graphene Aerogel Composites

引用

Chinese Journal of Chemistry 2023年第17期41卷 2125-2131页

作者： Yunlong Ma ruiyang li Shichang Luo Xiran Shen Rao Tao Yinghua Jin Wei Zhang li Qiu Yunnan Key Laboratory for Micro/Nano Materials&Technology National Centerfor International Research on Photoelectric and Energy MaterialsSchoolof Materialsand EnergyYunnan UniversityKunmingYunnan 650091China Department of Chemistry University of Colorado BoulderBoulderColorado 80309USA

Comprehensive Summary,Although polyimides(PIs)have shown great potential for a broad range of applications,it remains very challenging to achieve the malleability,rehealability and recyclability for PIs and their composites targeting various applications,particularly for the rapidly emerging flexible and stretchable ***,malleable conductive poly(imide-imine)hybrid(PIIH)vitrimer-graphene aerogel(GA)composites have been prepared,for the first time,via simple sol-gel film formation followed by *** resulting PIIH-GA composites exhibit not only the highly desired properties of thermosetting(strong mechanical strength)and thermoplastic(reprocessability)polymers,but also good conductivity enabled by the GA ***3-GA-10(with 10 wt%GA)showed one of the highest electrical conductivities(26.7 S/m)for PI-based composites,as well as good electromagnetic interference(EMI)shielding ***,the PIIH-GA films could maintain good performance during stretching and even after chemical recycling,which opens new opportunities for flexible and sustainable electronics development.

关键词： Sol-gel processes Thin films Sustainable chemistry Polyimide thermoset Dynamic covalent bond/Recyclable polymers EMI shielding

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Monolithic polyimine vitrimer/graphene aerogel composites

引用

Chinese Chemical Letters 2023年第2期34卷 529-533页

作者： Jinye Zhang Shichang Luo Yunlong Ma ruiyang li Yinghua Jin li Qiu Wei Zhang Yunnan Key Laboratory for Micro/Nano Materials&Technology National Center for International Research on Photoelectric and Energy MaterialsSchool of Materials and EnergyYunnan UniversityKunming 650091China Department of Chemistry University of Colorado BoulderBoulderCO 80309United States

Graphene-polymer composites have attracted great attention as sensing materials due to their tailorable electrical conductivity, physicochemical properties, and sensitivity to geometric and functional ***, we report the first example of cylindrical monolithic polyimine vitrimer/graphene composites with excellent mechanical, compressive, rehealable and recyclable, and piezoresistive properties via simple infiltration of polymer monomers into the pores of graphene aerogel followed by thermal curing. The composites exhibit excellent durable compressibility(negligible reduction in the compression properties even after 3000 consecutive compression cycles), rapid recovery to the original size upon stress released,high compressive strength(up to 1.2 MPa), and high conductivity(up to 79 S/m). Excellent piezoresistive properties were observed, displaying consistent and reliable change of the electrical resistance with the compression ratio. Furthermore, rehealing with ~100% recovery of the compressive strength and electric conductivity was achieved under mild rehealing conditions, which is highly desired but has rarely been reported for electronic materials. The facile strategy for fabrication of rehealable monolithic polymer/GAs can open new possibilities for the sustainable development of composites with high electrical conductivity for various applications such as sensing, health monitoring, and movement detection.

关键词： Vitrimer Graphene aerogel Polyimine Rehealable Piezoresistive Monolithic

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Critical Role of Fillers in Composite Polymer Electrolytes for lithium Battery

引用

Nano-Micro Letters 2023年第5期15卷 339-375页

作者： Xueying Yang Jiaxiang liu Nanbiao Pei Zhiqiang Chen ruiyang li lijun Fu Peng Zhang Jinbao Zhao College of Energy Xiamen UniversityXiamen 361102People’s Republic of China State Key Laboratory of Physical Chemistry of Solid Surfaces Collaborative Innovation Centre of Chemistry for Energy MaterialsState-Province Joint Engineering Laboratory of Power Source Technology for New Energy VehicleEngineering Research Center of Electrochemical TechnologyMinistry of EducationCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005People’s Republic of China College of Energy Nanjing Technical UniversityNanjing 211816People’s Republic of China

With excellent energy densities and highly safe performance,solidstate lithium batteries(SSLBs)have been hailed as promising energy storage ***-state electrolyte is the core component of SSLBs and plays an essential role in the safety and electrochemical performance of the *** polymer electrolytes(CPEs)are considered as one of the most promising candidates among all solid-state electrolytes due to their excellent comprehensive *** this review,we briefly introduce the components of CPEs,such as the polymer matrix and the species of fillers,as well as the integration of fillers in the *** particular,we focus on the two major obstacles that affect the development of CPEs:the low ionic conductivity of the electrolyte and high interfacial *** provide insight into the factors influencing ionic conductivity,in terms of macroscopic and microscopic aspects,including the aggregated structure of the polymer,ion migration rate and carrier *** addition,we also discuss the electrode-electrolyte interface and summarize methods for improving this *** is expected that this review will provide feasible solutions for modifying CPEs through further understanding of the ion conduction mechanism in CPEs and for improving the compatibility of the electrode-electrolyte interface.

关键词： Composite polymer electrolytes Fillers Ionic conductivity Electrode-electrolyte interface

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：