检索结果-南通市图书馆

Resource prediction and assessment based on 3D/4D big data modeling and deep integration in key ore districts of North China

在线全文

学校读者我要写书评

暂无评论

Science China Earth Sciences 2021年第9期64卷 1590-1606页

作者： Gongwen WANG Zhiqiang ZHANG ruixi li Junjian li Deming SHA Qingdong ZENG Zhenshan PANG Dapeng li Leilei HUANG School of Earth Sciences and Resources China University of Geosciences(Beijing)Beijing100083China Tianjin Geological Survey Center of China Geological Survey Tianjin300170China Shenyang Geological Survey Center of China Geological Survey Shenyang110000China Key Laboratory of Mineral Resources Institute of Geology and GeophysicsChinese Academy of SciencesBeijing100029China Institutions of Earth Science Chinese Academy of SciencesBeijing100029China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing100049China Development Research Center of China Geological Survey Beijing100037China Shandong Academy of Geological Sciences Jinan250013China

The North China district has been subjected to significant research with regard to the ore-forming dynamics,processes,and quantitative forecasting of gold deposits;it accounts for the highest number of gold reserves and annual products in *** on the top-level design of geoscience theory and the method adopted by the National Key R&D Project(deep process and metallogenic mechanism of North China Craton(NCC)metallogenic system),this paper systematically collects and constructs the geoscience data(district,camp,and deposit scales)in four key gold districts of North China(Jiaojia-Sanshandao,Southern Zhaoping,Wulong,and Qingchengzi).The settings associated with the geological dynamics of gold deposits were quantitatively and synthetically analyzed,namely:NCC destruction,metallogenic events,genetic models,and exploration ***-dimensional(3D)and four-dimensional(4D)geological modeling was performed using the big data on the districts,while the district-scale 3D exploration criteria were integrated to construct a quantitative exploration *** them,FLAC3D modelling and the Geo Cube software(version 3.0)were used to implement the numerical simulation of the 3D geological models and the constraints of the fluid saturation parameters of the Jiaojia fault to reconstruct the 4D fault structure models of the Jiaojia fault(with a depth of 5000 m).Using Geo Cube3.0,multiple integration modules(general weights of evidence(Wof E),Boost Wof E,Fuzzy Wof E,Logistic Regression,Information Entropy,and Random Forest)and exploration criteria were integrated,while the C-V fractal classification of A,B and C targets in four districts was carried *** research results are summarized in the following four areas:(1)Four gold districts in the study area have more than three targets(the depth is 3000 m),and the class A,B and C targets exhibit a good spatial correlation with gold bodies that are controlled by mining engineering at depths greater than 1000 m.(2)The Boost Wof

关键词： Geoscience big data 3D/4D modeling Weights of evidence Random forest Target optimization and resources assessment Gold district in North China

基于Node-RED的基建现场微气象监测与告警系统设计与实现

在线全文

学校读者我要写书评

暂无评论

科学技术创新 2024年第2期 119-122页

作者：李瑞喜何锐辛卫东张博北京洛斯达科技发展有限公司北京

为了更好地满足输变电工程基建现场应用中对现场环境数据监测与告警的需求,本文设计实现了一种基于Node-RED的基建现场微气象监测与告警系统。该系统通过搭建基于Node-RED的监测预警服务,能够快速完成设备接入,实时监测PM2.5等各项微气... 详细信息

为了更好地满足输变电工程基建现场应用中对现场环境数据监测与告警的需求,本文设计实现了一种基于Node-RED的基建现场微气象监测与告警系统。该系统通过搭建基于Node-RED的监测预警服务,能够快速完成设备接入,实时监测PM2.5等各项微气象指标,并且能够通过自动执行预设的处置策略就地进行告警或将数据推送至相关平台。该系统可以有效提升基建现场环境监测与告警的效率,在推进电力基建领域的数字化、智能化转型方面具有显著意义。

关键词： Node-RED 变电工程基建现场监测告警

The small GTPase RABA2a recruits SNARE proteins to regulate the secretory pathway in parallel with the exocyst complex in Arabidopsis

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2022年第3期15卷 398-418页

作者： Lei Pang Zhiming Ma Xi Zhang Yuanzhi Huang Ruili li Yansong Miao ruixi li Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes Institute of Plant and Food ScienceSchool of Life SciencesSouthern University of Science and TechnologyShenzhen 518055China School of Biological Sciences Nanyang Technological UniversitySingapore 637551Singapore College of Biological Sciences and Technology Beijing Forestry UniversityBeijing 100083China

Delivery of proteins to the plasma membrane occurs via secretion,which requires tethering,docking,priming,and fusion of *** yeast and mammalian cells,an evolutionarily conserved RAB GTPase activation cascade functions together with the exocyst and SNARE proteins to coordinate vesicle transport with fusion at the plasma ***,it is unclear whether this is the case in *** this study,we show that the small GTPase RABA2a recruits and interacts with the VAMP721/722-SYP121-SNAP33 SNARE ternary complex for membrane *** immunoprecipitation coupled with mass spectrometry analysis followed by the validatation with a series of biochemical assays,we identified the SNARE proteins VAMP721 and SYP121 as the interactors and downstream effectors of *** expreiments showed that RABA2a interacts with all members of the SNARE complex in its GTP-bound form and modulates the assembly of the VAMP721/722-SYP121-SNAP33 SNARE ternary ***,we did not observe the interaction of the exocyst subunits with either RABA2a or theSNARE proteins in several different *** RABA2a inactivation affects the subcellular localization or assembly of the exocystnor the exocyst subunit mutant exo84b shows the disrupted RABA2a-SNARE association or SNARE assembly,suggesting that the RABA2a-SNARE-and exocyst-mediated secretory pathways are largely ***,our live imaging experiments reveal that the two sets of proteins follow non-overlapping trafficking routes,and genetic and cell biologyanalyses indicate that the two pathways select different ***,we demonstrate that the plant-specific RABA2a-SNARE pathway is essential for the maintenance of potassium homeostasis in Arabisopsis ***,our findings imply that higher plants might have generated different endomembrane sorting pathways during evolution and may enable the highly conserved endomembrane proteins to participate in plant-specific traffi

关键词： exocyst RABA2a secretory process SNARE complex

超微粉碎技术在中药制备领域的应用与研究进展

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国医药工业杂志 2024年第2期55卷 187-195,216页

作者：李蕊汐王闯刘燕陈宇洲向蓓蓓天津中医药大学中药学院天津301617 沈阳药科大学中药学院辽宁沈阳110016 天津市中医药研究院附属医院药学部天津300120 天津市中药功效物质重点实验室天津300074

本综述介绍了常用超微粉碎设备的原理、结构及发展方向;概括了超微粉碎技术在中药制备领域的应用,如提高中药破壁率、优化中药理化性质、促进中药浸提、提高中药成分药效、便于中药后续加工。阐述了粒子设计技术与中药粉体技术的结合原... 详细信息

本综述介绍了常用超微粉碎设备的原理、结构及发展方向;概括了超微粉碎技术在中药制备领域的应用,如提高中药破壁率、优化中药理化性质、促进中药浸提、提高中药成分药效、便于中药后续加工。阐述了粒子设计技术与中药粉体技术的结合原理。此外,对中药超微粉末的粒径测定方法、细胞破壁率评价方法和药动学-药效学评价方法提出建议。最后,展望了超微粉碎技术的发展前景,总结了该技术亟待解决的问题,以期为超微粉碎技术在中药领域的应用提供支持。

关键词：超微粉碎技术超微粉碎设备中药粉末粒子设计技术质量评价

癌症患者人生目标调整能力及其对身心健康影响的研究新进展

在线全文

学校读者我要写书评

暂无评论

中国全科医学 2024年第23期27卷 2822-2828页

作者：冉倬睿孙睿歆贾婧怡车照宇黎芮希何亚平楚翘上海交通大学医学院附属瑞金医院上海市200025 上海交通大学医学院医学技术学院医学检验技术系上海市200025 上海交通大学医学院上海市200025 上海交通大学医学院公共卫生学院上海市200025 上海交通大学中国医院发展研究院卫生技术评估研究所上海市200025

罹患癌症是一件重大创伤事件,对个体人生目标的追求造成严重干扰,并导致多种情绪障碍。而合理地调整人生目标有利于患者重建人生方向,改善身心健康。本文通过文献综述的方式,梳理国内外有关癌症影响患者人生目标追求的研究现状,并归纳... 详细信息

罹患癌症是一件重大创伤事件,对个体人生目标的追求造成严重干扰,并导致多种情绪障碍。而合理地调整人生目标有利于患者重建人生方向,改善身心健康。本文通过文献综述的方式,梳理国内外有关癌症影响患者人生目标追求的研究现状,并归纳现有文献中有关癌症患者的目标调整行为及其对患者身心健康影响的研究进展。文献综述表明,确诊癌症对患者人生的目标追求造成的影响主要表现为对目标追求的自我效能感、目标追求能力及目标优先级设定的影响。而合理的目标调整行为有利于改善患者的身心健康,包括:促进积极情绪、缓解消极情绪、减轻躯体不适症状及提升生活质量。因此,未来针对癌症患者情绪健康的干预设计可立足于指导患者对人生目标进行重新规划和调整,以此提高患者的生活质量、促进情绪健康、改善疾病预后。

关键词：肿瘤目标调整心理健康生活质量疾病预后综述

Timing of formation of the Hongdonggou Pb-Zn polymetallic ore deposit,Henan Province,China:Evidence from Rb-Sr isotopic dating of sphalerites

在线全文

学校读者我要写书评

暂无评论

Geoscience Frontiers 2017年第3期8卷 605-616页

作者： Fan Yang Gongwen Wang Huawen Cao ruixi li li Tang Yufeng Huang Hao Zhang Fei Xue Wenjuan Jia Nana Guo School of Earth Sciences and Resources China University of Geosciences Beijing29 Xueyuan RoadBeijing 100083China Chengdu Center China Geological SurveyChengdu 610081China Luanchuan Bureau of Geology and Resources Luoyang 417500China

The Hongdonggou Pb-Zn polymetallic ore deposit, located in the southwestern part of the Luanchuan Mo-W-Pb-Zn-Ag polymetallic ore mineralization in Henan Province, China, is an important part of the East Qinling metallogenic belt. The orebodies in the deposit, which are vein, bedded and lenticular, are mainly hosted in the syenite porphyry, and formed within the carbonate and clastic rocks of the Yuku and Qiumugou formations partially. The genesis of the deposit has previously been argued to be of hydrothermal-vein type or of skarn-hydrothermal type. In this study, we report the results of Rb-Sr isotopic dating based on sphalerites from the main orebody of the Hongdonggou Pb-Zn polymetallic ore deposit, which yield an isochron age of 135.7 ± 3.2 Ma, constraining the timing of mineralization as early Cretaceous. The age is close to those reported for the Pb-Zn deposits in the Luanchuan ore belt. The （87Sr/86Sr）i values of the sphalerites （0.71127± 0.00010） are lower than that of terrigenous silicates （0.720） and higher than the mantle （0.707）, suggesting that the metallogenic components were mainly derived through crust-mantle mixing. Combining the results from this study with those from previous work, we propose that the Hongdonggou Pb-Zn polymetallic ore deposit is a hydrothermal-vein deposit associated with the early Cretaceous tectonothermal event, and the mineralization is controlled by NW- and near EW-trending faults in the Luanchuan Mo-W-Pb-Zn-Ag polymetallic ore concentration belt.

关键词： Sphalerite Rb-Sr geochronology Metallogeny Pb-Zn deposit Crust-mantle interaction Luanchuan ore belt

在线全文

学校读者我要写书评

暂无评论

生脉饮的化学成分、药理作用和临床应用进展

天津中医药大学学报 2024年第6期43卷 565-570页

作者：王萍赵姿雯王丁丁王韦博李蕊汐陈宇洲天津中医药大学中药学院天津301617 天津市中药功效物质重点实验室天津301617

生脉饮是由红参、麦冬、五味子3味药组成的常用中药经典方剂,具有益气复脉、养阴生津的作用。现代研究发现,生脉饮的化学成分主要包括皂苷类、木脂素类、高异黄酮类、多糖类和有机酸类等。相关药理学实验研究表明,生脉饮具有抗心律失常... 详细信息

生脉饮是由红参、麦冬、五味子3味药组成的常用中药经典方剂,具有益气复脉、养阴生津的作用。现代研究发现,生脉饮的化学成分主要包括皂苷类、木脂素类、高异黄酮类、多糖类和有机酸类等。相关药理学实验研究表明,生脉饮具有抗心律失常、抗心力衰竭、抗肿瘤等药理作用,临床上常与各类常规治疗药物联合使用发挥疗效,从而改善患者的临床症状。文章对近年来生脉饮的化学成分、药理作用和临床应用的研究进行了系统的阐述,以期为该方剂的进一步研究及开发利用提供支持和参考。

关键词：生脉饮化学成分药理作用临床应用

Terminals and synapses of A2A R-expressing neurons from caudate putamen in mouse lateral globus pallidus:a light and electron microscopic study

在线全文

学校读者我要写书评

暂无评论

Terminals and synapses of A2A R-expressing neurons from caud...

Rabies virus-traced monosynaptic inputs supplying vasopressin neurons in supraoptic nucleus

中国解剖学会2015年年会

作者： Yuan Xiangshan Huang Zhili li ruixi Departments of Anatomy Histology and Embryologyand PharmacologySchool of Basic Medical SciencesFudan University

Based on our previousresults that the neurons expressing adenosine Areceptors(AR) in caudate putamen(CPu)project their axons to lateral globus pallidus(LGP)and implicate in mediating the physiological sleep,we try fur...

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Rabies virus-traced monosynaptic inputs supplying vasopressi...